Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Beta cells is the predominant cell type in the pancreatic islets. The beta cells are particularly important because they make insulin.

Gene expression markers for Beta cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
16
Hs INS 0.009 1 0 0.047 0 1 Beta cells Endoderm Pancreas IDDM2 insulin Yflag
12
Mm Hs IAPP 0.023 1 1 0.035 0.018 3 Beta cells Endoderm Pancreas AMYLIN islet amyloid polypeptide flag
4
Mm INS2 0.02 0 0.833 0 0.023 1 Beta cells Endoderm Pancreas insulin II flag
2
Mm Hs NKX6-1 0.006 0.773 0.786 0.005 0.003 4 Beta cells Endoderm Pancreas Nkx6.1,NKX6A NK6 homeobox 1 flag
1
Mm Hs GJD2 0.005 0.591 0.452 0.002 0.004 2 Beta cells Endoderm Pancreas CX36,GJA9 gap junction protein delta 2 flag
1
Mm Hs PDX1 0.005 0.682 0.69 0.001 0.003 4 Beta cells Endoderm Pancreas IDX-1,STF-1,PDX-1,MODY4,IPF1 pancreatic and duodenal homeobox 1 Yflag
1
Mm Hs SLC2A2 0.007 0 0 0.002 0 3 Beta cells Endoderm Pancreas GLUT2 solute carrier family 2 member 2 Yflag
1
Mm INS1 0.018 0 1 0 0.02 1 Beta cells Endoderm Pancreas insulin I flag
1
Mm Hs NKX2-2 0.002 0.727 0.119 0.005 0 6 Beta cells Endoderm Pancreas NKX2.2,NKX2B NK2 homeobox 2 flag
1
Mm Hs NPY 0.015 0.136 0.238 0.005 0.016 6 Beta cells Endoderm Pancreas PYY4 neuropeptide Y flag
1
Mm Hs MAFA 0.002 0.5 0.667 0 0 1 Beta cells Endoderm Pancreas RIPE3b1,hMafA MAF bZIP transcription factor A flag
0
Mm Hs PFKFB2 0.001 0.273 0.071 0.003 0 1 Beta cells Endoderm Pancreas 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 flag
0
Mm Hs HOPX 0.033 0.864 0.333 0.086 0.021 10 Beta cells Endoderm Pancreas LAGY,OB1,NECC1,SMAP31 HOP homeobox flag
0
Mm Hs PAX6 0.049 0.909 0.786 0.008 0.057 8 Beta cells Endoderm Pancreas D11S812E,AN2 paired box 6 Yflag
0
Mm Hs MAFB 0.053 0.773 0.357 0.054 0.052 6 Beta cells Endoderm Pancreas KRML MAF bZIP transcription factor B Yflag
0
Mm Hs CASR 0.001 0.273 0.095 0 0 4 Beta cells Endoderm Pancreas FHH,NSHPT,GPRC2A,HHC,HHC1 calcium sensing receptor Yflag
0
Mm Hs EDARADD 0.001 0.045 0 0.002 0.001 1 Beta cells Endoderm Pancreas EDAR associated death domain Yflag
0
Hs SCGB2A1 0.003 0.818 0 0.012 0 3 Beta cells Endoderm Pancreas UGB3,LPHC,MGC71973,MGB2 secretoglobin family 2A member 1 flag
0
Mm Hs TGFBR3 0.019 0 0 0.016 0 1 Beta cells Endoderm Pancreas betaglycan,BGCAN transforming growth factor beta receptor 3 flag
0
Mm Hs ADCYAP1 0.003 0.773 0 0.001 0.003 1 Beta cells Endoderm Pancreas adenylate cyclase activating polypeptide 1 flag
0
Mm Hs SH3GL2 0.025 0.045 0 0.002 0 2 Beta cells Endoderm Pancreas SH3P4,SH3D2A,CNSA2,EEN-B1 SH3 domain containing GRB2 like 2, endophilin A1 flag
0
Mm Hs NEUROD1 0.038 0.909 0.786 0.017 0.041 8 Beta cells Endoderm Pancreas BETA2,BHF-1,NeuroD,bHLHa3,MODY6,NEUROD neuronal differentiation 1 Yflag
0
Mm Hs ISL1 0.028 0.682 0.738 0.009 0.029 13 Beta cells Endoderm Pancreas Isl-1,ISLET1 ISL LIM homeobox 1 flag
0
Mm Hs RGS16 0.01 0.136 0 0.02 0 3 Beta cells Endoderm Pancreas A28-RGS14,RGS-r regulator of G protein signaling 16 flag
0
Mm Hs SMAD9 0.002 0 0 0.009 0 2 Beta cells Endoderm Pancreas SMAD8,SMAD8/9,MADH9 SMAD family member 9 Yflag
0
Mm Hs SIX3 0.014 0.045 0 0.003 0 3 Beta cells Endoderm Pancreas HPE2 SIX homeobox 3 Yflag
0
Mm Hs BMP5 0.002 0.091 0 0.006 0.001 2 Beta cells Endoderm Pancreas bone morphogenetic protein 5 flag
0
Mm Hs PIR 0.011 0 0 0.016 0.009 1 Beta cells Endoderm Pancreas pirin flag
0
Mm Hs STXBP5 0.004 0 0 0.003 0 2 Beta cells Endoderm Pancreas tomosyn,LLGL3 syntaxin binding protein 5 flag
0
Mm Hs DLK1 0.055 0.682 0.333 0.042 0.057 5 Beta cells Endoderm Pancreas FA1,pG2,Pref-1,ZOG,Delta1 delta like non-canonical Notch ligand 1 flag
0
Mm Hs MEG3 0.288 0.909 0.833 0.11 0.334 3 Beta cells Endoderm Pancreas GTL2,NCRNA00023,LINC00023,onco-lncRNA-83 maternally expressed 3 flag
0
Mm Hs GCGR 0.001 0 0 0 0.001 1 Beta cells Endoderm Pancreas GGR glucagon receptor Yflag
0
Mm Hs LMX1A 0.003 0 0 0.001 0.003 2 Beta cells Endoderm Pancreas LMX1.1,LMX1 LIM homeobox transcription factor 1 alpha flag
0
Mm Hs JPH3 0.024 0 0 0 0.03 2 Beta cells Endoderm Pancreas JP-3,CAGL237,HDL2,JP3,TNRC22 junctophilin 3 Yflag
0
Mm Hs CD40 0.012 0 0 0.013 0.011 10 Beta cells Endoderm Pancreas Bp50,TNFRSF5 CD40 molecule Yflag
0
Mm Hs HAMP 0.002 0 0 0.004 0.002 4 Beta cells Endoderm Pancreas LEAP-1,HEPC,HFE2B,LEAP1 hepcidin antimicrobial peptide Yflag
0
Mm Hs EZH1 0.002 0 0 0.001 0.002 1 Beta cells Endoderm Pancreas KIAA0388,KMT6B enhancer of zeste 1 polycomb repressive complex 2 subunit flag
0
Mm Hs NTRK1 0.004 0 0 0 0.005 4 Beta cells Endoderm Pancreas TRKA,MTC neurotrophic receptor tyrosine kinase 1 Yflag
0
Mm Hs NKX6-2 0.024 0 0 0.001 0.03 3 Beta cells Endoderm Pancreas NKX6B,GTX,NKX6.1 NK6 homeobox 2 flag
0
Mm Hs FXYD2 0.025 0.364 0 0.002 0.031 6 Beta cells Endoderm Pancreas MGC12372,ATP1G1,HOMG2 FXYD domain containing ion transport regulator 2 Yflag
0
Mm Hs RIMS1 0.01 0 0 0.001 0 1 Beta cells Endoderm Pancreas KIAA0340,RIM1,RAB3IP2,CORD7 regulating synaptic membrane exocytosis 1 Yflag
0
Mm Hs EFNA5 0.029 0 0.024 0.025 0.03 3 Beta cells Endoderm Pancreas AF1,LERK7,EPLG7 ephrin A5 flag
0
Mm Hs NPTX2 0.008 0.818 0 0.013 0.007 2 Beta cells Endoderm Pancreas neuronal pentraxin 2 flag
0
Mm Hs PAX4 0.001 0 0 0 0.001 2 Beta cells Endoderm Pancreas MODY9 paired box 4 Yflag
0
Mm Hs PCSK2 0.032 0.909 0.857 0.019 0.033 4 Beta cells Endoderm Pancreas SPC2,NEC2 proprotein convertase subtilisin/kexin type 2 flag
0
Mm Hs G6PC2 0.004 0.864 0.786 0.005 0 1 Beta cells Endoderm Pancreas IGRP glucose-6-phosphatase catalytic subunit 2 flag
0
Mm Hs SLC30A8 0.005 0.909 0 0.009 0 2 Beta cells Endoderm Pancreas ZnT-8 solute carrier family 30 member 8 Yflag
0
Mm ERO1LB 0.007 0 0.786 0 0.007 1 Beta cells Endoderm Pancreas ERO1-like beta (S. cerevisiae) flag
0
Mm Hs PCSK1 0.008 0.818 0.786 0.004 0.006 5 Beta cells Endoderm Pancreas PC1,NEC1 proprotein convertase subtilisin/kexin type 1 Yflag
0
Mm Hs SCGN 0.014 1 0 0.023 0 6 Beta cells Endoderm Pancreas SECRET,DJ501N12.8,SEGN,CALBL secretagogin, EF-hand calcium binding protein flag
0
Mm Hs IGF2 0.013 0.045 0 0.046 0.001 8 Beta cells Endoderm Pancreas FLJ44734,IGF-II,C11orf43 insulin like growth factor 2 Yflag
0
Mm Hs SYT13 0.029 0.591 0 0.003 0 2 Beta cells Endoderm Pancreas KIAA1427 synaptotagmin 13 flag
0
Mm Hs FFAR2 0.01 0 0.429 0 0.011 3 Beta cells Endoderm Pancreas FFA2R,GPR43 free fatty acid receptor 2 flag
-1
Mm Hs SIX2 0.001 0 0 0.002 0 2 Beta cells Endoderm Pancreas SIX homeobox 2 flag

Datasets with computationally identified Beta cells

SRA SRS tissue cluster cell type p-value FDR View
SRA701877 SRS3279684 Pancreatic islets 0 Beta cells 6.81E-12 8.38E-9 view data
SRA701877 SRS3279694 Pancreatic islets 1 Beta cells 6.41E-7 1.69E-4 view data
SRA823298 SRS4144447 Beta cells 2 Beta cells 3.60E-11 2.50E-8 view data
SRA823298 SRS4144447 Beta cells 3 Beta cells 1.23E-7 4.26E-5 view data
SRA701877 SRS3279692 Pancreatic islets 0 Beta cells 3.63E-14 2.74E-11 view data
SRA701877 SRS3279692 Pancreatic islets 1 Beta cells 6.61E-15 6.67E-12 view data
SRA701877 SRS3279685 Pancreatic islets 0 Beta cells 2.02E-13 1.60E-10 view data
SRA745567 SRS3600294 Pancreatic islets 7 Beta cells 9.59E-11 1.61E-7 view data
SRA745567 SRS3600300 Pancreatic islets 4 Beta cells 6.67E-11 1.53E-8 view data
SRA745567 SRS3600300 Pancreatic islets 9 Beta cells 4.72E-6 4.18E-4 view data
SRA745567 SRS3600300 Pancreatic islets 19 Beta cells 5.28E-15 2.57E-12 view data
SRA745567 SRS3600297 Pancreatic islets 8 Beta cells 5.90E-12 4.52E-9 view data
SRA745567 SRS3600297 Pancreatic islets 14 Beta cells 1.32E-4 1.21E-2 view data
SRA701877 SRS3279686 Pancreatic islets 1 Beta cells 1.17E-10 5.81E-8 view data
SRA701877 SRS3279686 Pancreatic islets 2 Beta cells 6.62E-13 6.75E-10 view data
SRA745567 SRS3600295 Pancreatic islets 5 Beta cells 9.92E-5 1.19E-2 view data
SRA745567 SRS3600295 Pancreatic islets 10 Beta cells 4.45E-12 3.74E-9 view data
SRA585365 SRS3297652 Pancreas 10 Beta cells 1.41E-11 1.04E-8 view data
SRA701877 SRS3279691 Pancreatic islets 1 Beta cells 5.80E-15 6.67E-12 view data
SRA701877 SRS3279691 Pancreatic islets 2 Beta cells 1.74E-13 9.99E-11 view data
SRA585365 SRS3297653 Pancreas 9 Beta cells 3.99E-11 5.21E-8 view data
SRA653146 SRS2874280 Pancreas 0 Beta cells 6.09E-9 7.12E-7 view data
SRA653146 SRS2874280 Pancreas 8 Beta cells 2.29E-9 3.17E-7 view data
SRA653146 SRS2874280 Pancreas 9 Beta cells 2.43E-8 2.67E-6 view data
SRA653146 SRS2874280 Pancreas 11 Beta cells 2.44E-15 5.98E-13 view data
SRA653146 SRS2874280 Pancreas 17 Beta cells 4.70E-7 4.05E-5 view data
SRA784304 SRS3823099 Pancreatic progenitor cells 6 Beta cells 4.75E-9 3.76E-6 view data
SRA745567 SRS3600299 Pancreatic islets 7 Beta cells 4.90E-15 2.50E-12 view data
SRA745567 SRS3600299 Pancreatic islets 14 Beta cells 5.13E-10 1.16E-7 view data
SRA745567 SRS3600301 Pancreatic islets 3 Beta cells 1.44E-9 2.00E-7 view data
SRA745567 SRS3600301 Pancreatic islets 15 Beta cells 3.70E-6 3.17E-4 view data
SRA745567 SRS3600301 Pancreatic islets 20 Beta cells 1.44E-9 2.00E-7 view data
SRA745567 SRS3600301 Pancreatic islets 24 Beta cells 3.15E-5 2.08E-3 view data
SRA745567 SRS3600301 Pancreatic islets 25 Beta cells 4.08E-8 4.68E-6 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 1 Beta cells 1.33E-12 1.15E-9 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 3 Beta cells 1.50E-11 9.73E-9 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 5 Beta cells 3.67E-13 6.33E-10 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 8 Beta cells 1.53E-9 5.45E-7 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 9 Beta cells 4.88E-13 6.33E-10 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 10 Beta cells 3.02E-8 5.60E-6 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 11 Beta cells 4.38E-9 1.14E-6 view data
SRA784304 SRS3823097 Pancreatic progenitor cells 14 Beta cells 3.69E-11 1.92E-8 view data
SRA585365 SRS3297650 Pancreas 14 Beta cells 8.08E-12 4.17E-8 view data
SRA745567 SRS3600298 Pancreatic islets 5 Beta cells 9.20E-10 4.71E-7 view data
SRA745567 SRS3600298 Pancreatic islets 16 Beta cells 1.64E-4 1.58E-2 view data
SRA745567 SRS3600298 Pancreatic islets 22 Beta cells 6.63E-11 5.08E-8 view data
SRA701877 SRS3279688 Pancreatic islets 1 Beta cells 1.26E-7 6.67E-5 view data
SRA784304 SRS3823096 Pancreatic progenitor cells 3 Beta cells 3.65E-9 1.61E-6 view data
SRA638923 SRS2797103 Pancreas 4 Beta cells 7.29E-12 2.85E-9 view data
SRA745567 SRS3600296 Pancreatic islets 4 Beta cells 2.81E-11 3.49E-8 view data
SRA585365 SRS3297651 Pancreas 7 Beta cells 6.05E-10 3.44E-7 view data
SRA585365 SRS3297654 Pancreas 11 Beta cells 4.23E-11 6.02E-8 view data
SRA701877 SRS3279687 Pancreatic islets 0 Beta cells 3.19E-12 3.65E-9 view data
SRA745567 SRS3600293 Pancreatic islets 10 Beta cells 7.17E-9 7.58E-6 view data
SRA745567 SRS3600293 Pancreatic islets 17 Beta cells 2.46E-4 3.16E-2 view data
SRA701877 SRS3279689 Pancreatic islets 1 Beta cells 4.23E-16 7.53E-13 view data
SRA701877 SRS3279689 Pancreatic islets 2 Beta cells 3.87E-13 3.44E-10 view data
SRA701877 SRS3279695 Pancreatic islets 0 Beta cells 6.53E-11 5.01E-8 view data
SRA701877 SRS3279695 Pancreatic islets 9 Beta cells 2.67E-6 6.14E-4 view data
SRA701877 SRS3279695 Pancreatic islets 11 Beta cells 1.01E-4 1.11E-2 view data
SRA701877 SRS3279690 Pancreatic islets 0 Beta cells 6.30E-11 5.95E-8 view data
SRA701877 SRS3279690 Pancreatic islets 4 Beta cells 8.64E-10 4.08E-7 view data
SRA701877 SRS3279693 Pancreatic islets 1 Beta cells 6.08E-14 5.41E-11 view data
SRA701877 SRS3279693 Pancreatic islets 4 Beta cells 9.79E-5 8.55E-3 view data