Publications in the scientific literature

This list contains 4184 papers covering various topics of single cell sequencing. It is compiled by searching for keywords in abstracts and titles using data from ftp://ftp.ncbi.nlm.nih.gov/pubmed/updatefiles/ and ftp://ftp.ncbi.nlm.nih.gov/pubmed/baseline/. It is automatically updated daily. Rows in blue indicate papers in "high impact" journals.

Added within the last 24h to this list.

The study is about computer software/algorithm/database/pure bioinformatics.

The study is about a new method.

The study is a review or comment.

The study does not involve mammalian scRNA-seq data or raw data are not public.

Include studies:

First author Journal Title Pub. date DOI Citations Action
Debnath Methods Mol. Biol. Specimen Preparation for Single-Cell Sequencing Analysis of Skeletal Cells. 2021-09-01 10.1007/978-1-0716-0989-7_7 view
Yu Methods Mol. Biol. Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments. 2021-09-01 10.1007/978-1-0716-0849-4_9 view
Ferrall-Fairbanks Methods Mol. Biol. Investigating Inter- and Intrasample Diversity of Single-Cell RNA Sequencing Datasets. 2021-09-01 10.1007/978-1-0716-0849-4_10 view
Pinder Methods Mol. Biol. Use of Chlamydial Elementary Bodies as Probes to Isolate Pathogen-Specific Human Monoclonal Antibodies. 2021-09-01 10.1007/978-1-0716-0795-4_3 view
Massri Methods Mol. Biol. Methodologies for Following EMT In Vivo at Single Cell Resolution. 2021-09-01 10.1007/978-1-0716-0779-4_23 view
Dharmat Methods Mol. Biol. Single-Cell Capture, RNA-seq, and Transcriptome Analysis from the Neural Retina. 2020-12-01 10.1007/978-1-0716-0175-4_12 view
Hu NAR Genom Bioinform SIMPLEs: a single-cell RNA sequencing imputation strategy preserving gene modules and cell clusters variation. 2020-12-01 10.1093/nargab/lqaa077 view
Thibivilliers Curr Protoc Plant Biol Isolation of Plant Root Nuclei for Single Cell RNA Sequencing. 2020-12-01 10.1002/cppb.20120 view
Tanevski Life Sci Alliance Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data. 2020-11-01 10.26508/lsa.202000867 view
Leir Life Sci Alliance An atlas of human proximal epididymis reveals cell-specific functions and distinct roles for CFTR. 2020-11-01 10.26508/lsa.202000744 view
Tšuiko Reproduction PREIMPLANTATION GENETIC TESTING: Single-cell technologies at the forefront of PGT and embryo research. 2020-11-01 10.1530/REP-20-0102 view
Beaumont Application of Single-Cell Sequencing to Immunotherapy. 2020-11-01 10.1016/j.ucl.2020.07.005 view
Møller Life Sci Alliance Predicting gene regulatory networks from cell atlases. 2020-11-01 10.26508/lsa.202000658 view
Urrutia-Cabrera Neural Regen Res Using single cell transcriptomics to study the complexity of human retina. 2020-11-01 10.4103/1673-5374.282253 view
Park Am J Physiol Endocrinol Metab Holistic Characterization of Single Hepatocyte Transcriptome Responses to High Fat Diet. 2020-10-26 10.1152/ajpendo.00391.2020 view
Ste-Croix Phytopathology Genomic profiling of virulence in the soybean cyst nematode using single-nematode sequencing. 2020-10-25 10.1094/PHYTO-08-20-0348-FI view
Chen Bioinformatics Single-cell RNA-seq data semi-supervised clustering and annotation via structural regularized domain adaptation. 2020-10-24 10.1093/bioinformatics/btaa908 view
Fabian Science Lineage analysis reveals an endodermal contribution to the vertebrate pituitary. 2020-10-23 10.1126/science.aba4767 view
Vargo BMC Bioinformatics A rank-based marker selection method for high throughput scRNA-seq data. 2020-10-23 10.1186/s12859-020-03641-z view
Tang Development Neural crest lineage analysis: from past to future trajectory. 2020-10-23 10.1242/dev.193193 view
Rasouli Sci Immunol A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation. 2020-10-23 10.1126/sciimmunol.aba9953 view
McQuade Nat Commun Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. 2020-10-23 10.1038/s41467-020-19227-5 view
Xu Arterioscler Thromb Vasc Biol Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease. 2020-10-22 10.1161/ATVBAHA.120.314789 view
Chen Cancer Res Tumor fibroblast-derived FGF2 regulates expression of SPRY1 in esophageal tumor-infiltrating T cells and plays a role in T cell exhaustion. 2020-10-22 10.1158/0008-5472.CAN-20-1542 view
Johnson Sci Rep Spatial cell type composition in normal and Alzheimers human brains is revealed using integrated mouse and human single cell RNA sequencing. 2020-10-22 10.1038/s41598-020-74917-w view
Gu Sci Rep Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea. 2020-10-22 10.1038/s41598-020-75238-8 view
Zhao Cell Prolif Single-cell analysis identified lung progenitor cells in COVID-19 patients. 2020-10-22 10.1111/cpr.12931 view
Kalra FEBS J Challenges and possible solutions for decoding extranasal olfactory receptors. 2020-10-21 10.1111/febs.15606 view
Kubick Immun Inflamm Dis What has single-cell RNA sequencing revealed about microglial neuroimmunology? 2020-10-21 10.1002/iid3.362 view
Pervolarakis Cell Rep Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity. 2020-10-20 10.1016/j.celrep.2020.108273 view
Hamey Allergy Single-cell molecular profiling provides a high-resolution map of basophil and mast cell development. 2020-10-20 10.1111/all.14633 view
Tekman Gigascience A single-cell RNA-sequencing training and analysis suite using the Galaxy framework. 2020-10-20 10.1093/gigascience/giaa102 view
Zhang Glia Cell populations in neonatal rat peripheral nerves identified by single-cell transcriptomics. 2020-10-20 10.1002/glia.23928 view
Mould Am J Respir Crit Care Med Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults. 2020-10-20 10.1164/rccm.202005-1989OC view
Pariser J Clin Invest Lung megakaryocytes are immune modulatory cells. 2020-10-20 10.1172/JCI137377 view
Uddin ACS Chem Biol Visualizing HIF-1α mRNA in a Subpopulation of Bone Marrow-Derived Cells to Predict Retinal Neovascularization. 2020-10-20 10.1021/acschembio.0c00662 view
Swanson Acta Neuropathol Commun Identification of a dysfunctional microglial population in human Alzheimer's disease cortex using novel single-cell histology image analysis. 2020-10-20 10.1186/s40478-020-01047-9 view
Kapitansky Cells Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting. 2020-10-19 10.3390/cells9102320 view
Cambien PLoS Pathog Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics. 2020-10-19 10.1371/journal.ppat.1008660 view
Zhang Nat Commun Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development. 2020-10-19 10.1038/s41467-020-19012-4 view
Rodriques Nat Biotechnol RNA timestamps identify the age of single molecules in RNA sequencing. 2020-10-19 10.1038/s41587-020-0704-z view
Brbić Nat Methods MARS: discovering novel cell types across heterogeneous single-cell experiments. 2020-10-19 10.1038/s41592-020-00979-3 view
Amann-Zalcenstein Nat Immunol A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics. 2020-10-19 10.1038/s41590-020-0799-x view
Yang J Leukoc Biol Single-cell transcriptomics uncover distinct innate and adaptive cell subsets during tissue homeostasis and regeneration. 2020-10-18 10.1002/JLB.6MR0720-131R view
Lam J Am Heart Assoc Single-Cell Transcriptomics of Engineered Cardiac Tissues From Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveals Abnormal Developmental Trajectory and Intrinsic Contractile Defects in Hypoplastic Right Heart Syndrome. 2020-10-16 10.1161/JAHA.120.016528 view
Wu Cardiovasc Res Angiogenesis After Acute Myocardial Infarction. 2020-10-16 10.1093/cvr/cvaa287 view
Schmidt Genes (Basel) Developmental scRNAseq Trajectories in Gene- and Cell-State Space-The Flatworm Example. 2020-10-16 10.3390/genes11101214 view
Bulut Arterioscler Thromb Vasc Biol KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation. 2020-10-15 10.1161/ATVBAHA.120.314703 view
Borst Brain Pathol Deciphering the heterogeneity of myeloid cells during neuroinflammation in the single cell era. 2020-10-15 10.1111/bpa.12910 view
Fernández-Zapata Brain Pathol The use and limitations of single-cell mass cytometry for studying human microglia function. 2020-10-15 10.1111/bpa.12909 view
Tomar J Allergy Clin Immunol IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy. 2020-10-15 10.1016/j.jaci.2020.08.043 view
Kang Nat Biotechnol Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. 2020-10-14 10.1038/s41587-020-0715-9 view
Pool Nature The cellular basis of distinct thirst modalities. 2020-10-14 10.1038/s41586-020-2821-8 view
Song Nature Cell-type-specific 3D epigenomes in the developing human cortex. 2020-10-14 10.1038/s41586-020-2825-4 view
Kim Korean J Intern Med Single-cell transcriptomics: a new research technique for precision medicine in nephrology. 2020-10-14 10.3904/kjim.2020.415 view
Hughes Immunity Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. 2020-10-13 10.1016/j.immuni.2020.09.015 view
Fernandes Cell Rep Single-Cell Transcriptomics of Parkinson's Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses. 2020-10-13 10.1016/j.celrep.2020.108263 view
Panico Cardiovasc Res Defining circulating mononuclear cells in heart failure through single-cell RNA sequencing: new insights for an old disease. 2020-10-13 10.1093/cvr/cvaa156 view
Cooney Genome Biol Evol Single cell transcriptomics of ABEDINIUM reveals a new early-branching dinoflagellate lineage. 2020-10-12 10.1093/gbe/evaa196 view
Galletti Nat Immunol Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans. 2020-10-12 10.1038/s41590-020-0791-5 view
Soon Nat Immunol Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. 2020-10-12 10.1038/s41590-020-0800-8 view
Liu Nat Protoc Jointly defining cell types from multiple single-cell datasets using LIGER. 2020-10-12 10.1038/s41596-020-0391-8 view
Hie Cell Syst Leveraging Uncertainty in Machine Learning Accelerates Biological Discovery and Design. 2020-10-10 10.1016/j.cels.2020.09.007 view
Wang Int J Hematol Transcriptional heterogeneity of clonal plasma cells and immune evasion in immunoglobulin light chain amyloidosis. 2020-10-10 10.1007/s12185-020-03016-3 view
Aschenbrenner Gut Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance. 2020-10-09 10.1136/gutjnl-2020-321731 view
Sage Sci Rep Assessment of long non-coding RNA expression reveals novel mediators of the lung tumour immune response. 2020-10-09 10.1038/s41598-020-73787-6 view
Chattopadhyay Arterioscler Thromb Vasc Biol Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response. 2020-10-08 10.1161/ATVBAHA.120.315164 view
Xu Curr Osteoporos Rep The Effects of Calcitonin Gene-Related Peptide on Bone Homeostasis and Regeneration. 2020-10-08 10.1007/s11914-020-00624-0 view
Summers PLoS Biol Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system. 2020-10-08 10.1371/journal.pbio.3000859 view
Ma Mol Cancer Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing. 2020-10-08 10.1186/s12943-020-01264-9 view
Di Campli Eur Respir J The mononuclear phagocyte system contributes to fibrosis in post-transplant Obliterans Bronchiolitis. 2020-10-08 10.1183/13993003.00344-2020 view
Yao Nat Commun AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma. 2020-10-08 10.1038/s41467-020-18762-5 view
Chen Nat Commun Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma. 2020-10-08 10.1038/s41467-020-18916-5 view
Xiong Nat Commun A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response. 2020-10-08 10.1038/s41467-020-18546-x view
Shinozawa Gastroenterology High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids. 2020-10-08 10.1053/j.gastro.2020.10.002 view
Li J Allergy Clin Immunol Single Cell Transcriptomic Analysis Reveals Key Immune Cell Phenotypes in the lung of Asthma Exacerbation. 2020-10-08 10.1016/j.jaci.2020.09.032 view
Xu Methods Ensemble learning models that predict surface protein abundance from single-cell multimodal omics data. 2020-10-08 10.1016/j.ymeth.2020.10.001 view
Mevel Elife RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development. 2020-10-07 10.7554/eLife.60225 view
Wang IEEE/ACM Trans Comput Biol Bioinform Single-cell RNA Sequencing Data Clustering by Low-Rank Subspace Ensemble Framework. 2020-10-07 10.1109/TCBB.2020.3029187 view
Wang BMC Bioinformatics Impact of data preprocessing on cell-type clustering based on single-cell RNA-seq data. 2020-10-07 10.1186/s12859-020-03797-8 view
Kok Oncogenesis Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors. 2020-10-07 10.1038/s41389-020-00270-2 view
Li Nature Microglia-organized scar-free spinal cord repair in neonatal mice. 2020-10-07 10.1038/s41586-020-2795-6 view
Kobayashi J Autoimmun Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis. 2020-10-07 10.1016/j.jaut.2020.102547 view
Hong Am J Respir Crit Care Med Single-cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. 2020-10-06 10.1164/rccm.202006-2169OC view
Zhu Cell Death Dis Mesenchymal stem cells alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of Ly6C+ CD8+ T cells. 2020-10-06 10.1038/s41419-020-03036-1 view
Hou Nat Commun Predicting cell-to-cell communication networks using NATMI. 2020-10-06 10.1038/s41467-020-18873-z view
Kim Cell Rep Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies. 2020-10-06 10.1016/j.celrep.2020.108222 view
Wang Eur J Pharmacol Tissue distributions of antiviral drugs affect their capabilities of reducing viral loads in COVID-19 treatment. 2020-10-06 10.1016/j.ejphar.2020.173634 view
Li Stem Cell Reports Single-Cell RNA-Seq Reveals that CD9 Is a Negative Marker of Glucose-Responsive Pancreatic β-like Cells Derived from Human Pluripotent Stem Cells. 2020-10-06 10.1016/j.stemcr.2020.09.009 view
Carretta Int J Mol Sci Genomic Analysis of Hematopoietic Stem Cell at the Single-Cell Level: Optimization of Cell Fixation and Whole Genome Amplification (WGA) Protocol. 2020-10-06 10.3390/ijms21197366 view
Li Circulation Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue. 2020-10-06 10.1161/CIRCULATIONAHA.120.046528 view
Yasumizu Bioinformatics VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data. 2020-10-05 10.1093/bioinformatics/btaa859 view
Deng Nat Med Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas. 2020-10-05 10.1038/s41591-020-1061-7 view
Darden Shock Single Cell RNA-SEQ of Human Myeloid Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets with Unique Transcriptional Responses: A Pilot Study. 2020-10-05 10.1097/SHK.0000000000001671 view
Men Prospects for Use of Single-Cell Sequencing to Assess DNA Methylation in Asthma. 2020-10-03 10.12659/MSM.925514 view
Zhao SC2disease: a manually curated database of single-cell transcriptome for human diseases. 2020-10-03 10.1093/nar/gkaa838 view
Hémon Biochem Biophys Res Commun SLC7A11 as a biomarker and therapeutic target in HPV-positive head and neck Squamous Cell Carcinoma. 2020-10-03 10.1016/j.bbrc.2020.09.134 view
Zhao Generation of cortical neurons through large-scale expanding neuroepithelial stem cell from human pluripotent stem cells. 2020-10-02 10.1186/s13287-020-01939-6 view
Wu EMBO J. Stromal cell diversity associated with immune evasion in human triple-negative breast cancer. 2020-10-01 10.15252/embj.2019104063 view
Yilmaz Mol Syst Biol Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels. 2020-10-01 10.15252/msb.20209649 view
Venkatakrishnan Cell Death Discov Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2. 2020-10-01 10.1038/s41420-020-00321-y view
Kim Hepatol Commun Functionally Diverse Inflammatory Responses in Peripheral and Liver Monocytes in Alcohol-Associated Hepatitis. 2020-10-01 10.1002/hep4.1563 view
Kadota Front Genet Commentary: A Systematic Evaluation of Single Cell RNA-Seq Analysis Pipelines. 2020-10-01 10.3389/fgene.2020.00941 view
Wu PeerJ A robust semi-supervised NMF model for single cell RNA-seq data. 2020-10-01 10.7717/peerj.10091 view
Ray Brain Behav Immun A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction. 2020-10-01 10.1016/j.bbi.2020.05.078 view
Qiu Massively parallel and time-resolved RNA sequencing in single cells with scNT-seq. 2020-10-01 10.1038/s41592-020-0935-4 view
Kalinich Recent Results Cancer Res. Quantitative Analysis of Circulating Tumor Cells Using RNA-Based Digital Scoring. 2020-10-01 10.1007/978-3-030-26439-0_4 view
Yosef PLoS One Isolation and transcriptional characterization of mouse perivascular astrocytes. 2020-10-01 10.1371/journal.pone.0240035 view
Nagaoka J Immunother Cancer Deep immunophenotyping at the single-cell level identifies a combination of anti-IL-17 and checkpoint blockade as an effective treatment in a preclinical model of data-guided personalized immunotherapy. 2020-10-01 10.1136/jitc-2020-001358 view
Weber PhyDOSE: Design of follow-up single-cell sequencing experiments of tumors. 2020-10-01 10.1371/journal.pcbi.1008240 view
Zhang Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts. 2020-10-01 10.1093/jmcb/mjaa052 view
Patruno A review of computational strategies for denoising and imputation of single-cell transcriptomic data. 2020-10-01 10.1093/bib/bbaa222 view
Wu Comput Struct Biotechnol J Joint learning of multiple gene networks from single-cell gene expression data. 2020-10-01 10.1016/j.csbj.2020.09.004 view
Qi A spectral clustering with self-weighted multiple kernel learning method for single-cell RNA-seq data. 2020-10-01 10.1093/bib/bbaa216 view
Ramamoorthy EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism. 2020-10-01 10.1101/gad.340216.120 view
Zerrouk Identification of putative master regulators in rheumatoid arthritis synovial fibroblasts using gene expression data and network inference. 2020-10-01 10.1038/s41598-020-73147-4 view
Ibrahim Front Oncol Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. 2020-10-01 10.3389/fonc.2020.569985 view
Osborne Defining the First Part of the Oncogenic KRAS Journey. 2020-10-01 10.1016/j.stem.2020.09.009 view
Li Front Med (Lausanne) Evaluating Distribution and Prognostic Value of New Tumor-Infiltrating Lymphocytes in HCC Based on a scRNA-Seq Study With CIBERSORTx. 2020-10-01 10.3389/fmed.2020.00451 view
Attaf Front Immunol Corrigendum: FB5P-seq: FACS-Based 5-Prime End Single-Cell RNA-seq for Integrative Analysis of Transcriptome and Antigen Receptor Repertoire in B and T Cells. 2020-10-01 10.3389/fimmu.2020.02047 view
Li Front Immunol The Regulation of Exosome-Derived miRNA on Heterogeneity of Macrophages in Atherosclerotic Plaques. 2020-10-01 10.3389/fimmu.2020.02175 view
Wu Front Immunol Human Liver Macrophage Subsets Defined by CD32. 2020-10-01 10.3389/fimmu.2020.02108 view
Milichko Front Cell Dev Biol Novel Glial Cell Functions: Extensive Potency, Stem Cell-Like Properties, and Participation in Regeneration and Transdifferentiation. 2020-10-01 10.3389/fcell.2020.00809 view
Xu Cell Discov The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing. 2020-10-01 10.1038/s41421-020-00225-2 view
Kobak Mach Learn Knowl Discov Databases Heavy-tailed kernels reveal a finer cluster structure in t-SNE visualisations. 2020-10-01 10.1007/978-3-030-46150-8_8 view
Ebert Clin Transl Immunology Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy. 2020-10-01 10.1002/cti2.1191 view
Lu Cell Discov Single-cell transcriptome atlas of lung adenocarcinoma featured with ground glass nodules. 2020-10-01 10.1038/s41421-020-00200-x view
Teschendorff NPJ Genom Med Improved detection of tumor suppressor events in single-cell RNA-Seq data. 2020-10-01 10.1038/s41525-020-00151-y view
Li J Mol Cell Biol A new bioinformatics tool to recover missing gene expression in single-cell RNA sequencing data. 2020-09-30 10.1093/jmcb/mjaa053 view
Zhao Cancer Res. Transient activation of the Hedgehog-Gli pathway rescues radiotherapy-induced dry mouth via recovering salivary gland resident macrophages. 2020-09-30 10.1158/0008-5472.CAN-20-0503 view
Syage J. Virol. Single-cell RNA sequencing reveals the diversity of the immunological landscape following CNS infection by a murine coronavirus. 2020-09-30 10.1128/JVI.01295-20 view
Thrupp Cell Rep Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans. 2020-09-29 10.1016/j.celrep.2020.108189 view
Wolf Circulation Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100-Reactive CD4+ T-Regulatory Cells. 2020-09-29 10.1161/CIRCULATIONAHA.119.042863 view
Wong Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. 2020-09-29 10.1016/j.immuni.2020.09.001 view
Lin Genome Med Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions. 2020-09-29 10.1186/s13073-020-00776-9 view
Van Buren Genet. Epidemiol. TWO-SIGMA: A novel two-component single cell model-based association method for single-cell RNA-seq data. 2020-09-29 10.1002/gepi.22361 view
Phan Elife Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds. 2020-09-29 10.7554/eLife.60066 view
Gyllborg Nucleic Acids Res. Hybridization-based in situ sequencing (HybISS) for spatially resolved transcriptomics in human and mouse brain tissue. 2020-09-29 10.1093/nar/gkaa792 view
Depuydt Circ. Res. Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics. 2020-09-28 10.1161/CIRCRESAHA.120.316770 view
Vazquez-Armendariz EMBO J. Multilineage murine stem cells generate complex organoids to model distal lung development and disease. 2020-09-28 10.15252/embj.2019103476 view
Song The HDAC Inhibitor Domatinostat Promotes Cell Cycle Arrest, Induces Apoptosis and Increases Immunogenicity of Merkel Cell Carcinoma Cells. 2020-09-28 10.1016/j.jid.2020.08.023 view
Courtney Small Bowel Resection Increases Paracellular Gut Barrier Permeability via Alterations of Tight Junction Complexes Mediated by Intestinal TLR4. 2020-09-28 10.1016/j.jss.2020.08.049 view
Kalra PLoS Genet. Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty. 2020-09-28 10.1371/journal.pgen.1009025 view
Hu Proc. Natl. Acad. Sci. U.S.A. Genetic landscape and autoimmunity of monocytes in developing Vogt-Koyanagi-Harada disease. 2020-09-28 10.1073/pnas.2002476117 view
Schumann Nat. Immunol. Functional CRISPR dissection of gene networks controlling human regulatory T cell identity. 2020-09-28 10.1038/s41590-020-0784-4 view
Jiang Expert Rev Respir Med Recent developments in the pathobiology of lung myofibroblasts. 2020-09-27 10.1080/17476348.2021.1829972 view
Ruiz-Villalba Circulation Single-Cell RNA-seq Analysis Reveals a Crucial Role for Collagen Triple Helix Repeat Containing 1 (CTHRC1) Cardiac Fibroblasts after Myocardial Infarction. 2020-09-25 10.1161/CIRCULATIONAHA.119.044557 view
Wendt Science A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding. 2020-09-25 10.1126/science.abb7709 view
Wang Signal Transduct Target Ther Nanoparticle enhanced combination therapy for stem-like progenitors defined by single-cell transcriptomics in chemotherapy-resistant osteosarcoma. 2020-09-25 10.1038/s41392-020-00248-x view
Cosgrove Hum. Mol. Genet. Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons. 2020-09-25 10.1093/hmg/ddaa213 view
Sun Bioinformatics BP4RNAseq: a babysitter package for retrospective and newly generated RNA-seq data analyses using both alignment-based and alignment-free quantification method. 2020-09-25 10.1093/bioinformatics/btaa832 view
Song Nucleic Acids Res. STAB: a spatio-temporal cell atlas of the human brain. 2020-09-25 10.1093/nar/gkaa762 view
Partel FEBS J. Spage2vec: Unsupervised representation of localized spatial gene expression signatures. 2020-09-25 10.1111/febs.15572 view
Feng Stem Cell Res Ther Immunosuppressive effects of mesenchymal stem cells on lung B cell gene expression in LPS-induced acute lung injury. 2020-09-25 10.1186/s13287-020-01934-x view
Conway J. Am. Soc. Nephrol. Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease. 2020-09-25 10.1681/ASN.2020060806 view
Milner Proc. Natl. Acad. Sci. U.S.A. Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population. 2020-09-25 10.1073/pnas.2008571117 view
Verrillo J. Neurosci. Methods A reliable strategy for single-cell RNA sequencing analysis using cryoconserved primary cortical cells. 2020-09-25 10.1016/j.jneumeth.2020.108960 view
Dangi JCI Insight Single-cell transcriptomics of mouse kidney transplants reveals a myeloid cell pathway for transplant rejection. 2020-09-24 10.1172/jci.insight.141321 view
Castagnola Genome Res. Agonist-induced Functional Analysis and Cell Sorting coupled with single-cell transcriptomics characterizes cell subtypes in normal and pathological brain. 2020-09-24 10.1101/gr.262717.120 view
Bengtsson Gonzales Sci Rep Intrinsic electrophysiological properties predict variability in morphology and connectivity among striatal Parvalbumin-expressing Pthlh-cells. 2020-09-24 10.1038/s41598-020-72588-1 view
Sharma Cell Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma. 2020-09-24 10.1016/j.cell.2020.08.040 view
Smith-Edwards Gastroenterology Sympathetic input to multiple cell types in mouse and human colon produces region-specific responses. 2020-09-24 10.1053/j.gastro.2020.09.030 view
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