Publications in the scientific literature

This list contains 4184 papers covering various topics of single cell sequencing. It is compiled by searching for keywords in abstracts and titles using data from and It is automatically updated daily. Rows in blue indicate papers in "high impact" journals.

Added within the last 24h to this list.

The study is about computer software/algorithm/database/pure bioinformatics.

The study is about a new method.

The study is a review or comment.

The study does not involve mammalian scRNA-seq data or raw data are not public.

Include studies:

First author Journal Title Pub. date DOI Citations Action
Debnath Methods Mol. Biol. Specimen Preparation for Single-Cell Sequencing Analysis of Skeletal Cells. 2021-09-01 10.1007/978-1-0716-0989-7_7 view
Yu Methods Mol. Biol. Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments. 2021-09-01 10.1007/978-1-0716-0849-4_9 view
Ferrall-Fairbanks Methods Mol. Biol. Investigating Inter- and Intrasample Diversity of Single-Cell RNA Sequencing Datasets. 2021-09-01 10.1007/978-1-0716-0849-4_10 view
Pinder Methods Mol. Biol. Use of Chlamydial Elementary Bodies as Probes to Isolate Pathogen-Specific Human Monoclonal Antibodies. 2021-09-01 10.1007/978-1-0716-0795-4_3 view
Massri Methods Mol. Biol. Methodologies for Following EMT In Vivo at Single Cell Resolution. 2021-09-01 10.1007/978-1-0716-0779-4_23 view
Dharmat Methods Mol. Biol. Single-Cell Capture, RNA-seq, and Transcriptome Analysis from the Neural Retina. 2020-12-01 10.1007/978-1-0716-0175-4_12 view
Hu NAR Genom Bioinform SIMPLEs: a single-cell RNA sequencing imputation strategy preserving gene modules and cell clusters variation. 2020-12-01 10.1093/nargab/lqaa077 view
Thibivilliers Curr Protoc Plant Biol Isolation of Plant Root Nuclei for Single Cell RNA Sequencing. 2020-12-01 10.1002/cppb.20120 view
Tanevski Life Sci Alliance Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data. 2020-11-01 10.26508/lsa.202000867 view
Leir Life Sci Alliance An atlas of human proximal epididymis reveals cell-specific functions and distinct roles for CFTR. 2020-11-01 10.26508/lsa.202000744 view
Tšuiko Reproduction PREIMPLANTATION GENETIC TESTING: Single-cell technologies at the forefront of PGT and embryo research. 2020-11-01 10.1530/REP-20-0102 view
Beaumont Application of Single-Cell Sequencing to Immunotherapy. 2020-11-01 10.1016/j.ucl.2020.07.005 view
Møller Life Sci Alliance Predicting gene regulatory networks from cell atlases. 2020-11-01 10.26508/lsa.202000658 view
Urrutia-Cabrera Neural Regen Res Using single cell transcriptomics to study the complexity of human retina. 2020-11-01 10.4103/1673-5374.282253 view
Park Am J Physiol Endocrinol Metab Holistic Characterization of Single Hepatocyte Transcriptome Responses to High Fat Diet. 2020-10-26 10.1152/ajpendo.00391.2020 view
Ste-Croix Phytopathology Genomic profiling of virulence in the soybean cyst nematode using single-nematode sequencing. 2020-10-25 10.1094/PHYTO-08-20-0348-FI view
Chen Bioinformatics Single-cell RNA-seq data semi-supervised clustering and annotation via structural regularized domain adaptation. 2020-10-24 10.1093/bioinformatics/btaa908 view
Fabian Science Lineage analysis reveals an endodermal contribution to the vertebrate pituitary. 2020-10-23 10.1126/science.aba4767 view
Vargo BMC Bioinformatics A rank-based marker selection method for high throughput scRNA-seq data. 2020-10-23 10.1186/s12859-020-03641-z view
Tang Development Neural crest lineage analysis: from past to future trajectory. 2020-10-23 10.1242/dev.193193 view
Rasouli Sci Immunol A distinct GM-CSF+ T helper cell subset requires T-bet to adopt a TH1 phenotype and promote neuroinflammation. 2020-10-23 10.1126/sciimmunol.aba9953 view
McQuade Nat Commun Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease. 2020-10-23 10.1038/s41467-020-19227-5 view
Xu Arterioscler Thromb Vasc Biol Cell-Type Transcriptome Atlas of Human Aortic Valves Reveal Cell Heterogeneity and Endothelial to Mesenchymal Transition Involved in Calcific Aortic Valve Disease. 2020-10-22 10.1161/ATVBAHA.120.314789 view
Chen Cancer Res Tumor fibroblast-derived FGF2 regulates expression of SPRY1 in esophageal tumor-infiltrating T cells and plays a role in T cell exhaustion. 2020-10-22 10.1158/0008-5472.CAN-20-1542 view
Johnson Sci Rep Spatial cell type composition in normal and Alzheimers human brains is revealed using integrated mouse and human single cell RNA sequencing. 2020-10-22 10.1038/s41598-020-74917-w view
Gu Sci Rep Characterization of rare spindle and root cell transcriptional profiles in the stria vascularis of the adult mouse cochlea. 2020-10-22 10.1038/s41598-020-75238-8 view
Zhao Cell Prolif Single-cell analysis identified lung progenitor cells in COVID-19 patients. 2020-10-22 10.1111/cpr.12931 view
Kalra FEBS J Challenges and possible solutions for decoding extranasal olfactory receptors. 2020-10-21 10.1111/febs.15606 view
Kubick Immun Inflamm Dis What has single-cell RNA sequencing revealed about microglial neuroimmunology? 2020-10-21 10.1002/iid3.362 view
Pervolarakis Cell Rep Integrated Single-Cell Transcriptomics and Chromatin Accessibility Analysis Reveals Regulators of Mammary Epithelial Cell Identity. 2020-10-20 10.1016/j.celrep.2020.108273 view
Hamey Allergy Single-cell molecular profiling provides a high-resolution map of basophil and mast cell development. 2020-10-20 10.1111/all.14633 view
Tekman Gigascience A single-cell RNA-sequencing training and analysis suite using the Galaxy framework. 2020-10-20 10.1093/gigascience/giaa102 view
Zhang Glia Cell populations in neonatal rat peripheral nerves identified by single-cell transcriptomics. 2020-10-20 10.1002/glia.23928 view
Mould Am J Respir Crit Care Med Airspace Macrophages and Monocytes Exist in Transcriptionally Distinct Subsets in Healthy Adults. 2020-10-20 10.1164/rccm.202005-1989OC view
Pariser J Clin Invest Lung megakaryocytes are immune modulatory cells. 2020-10-20 10.1172/JCI137377 view
Uddin ACS Chem Biol Visualizing HIF-1α mRNA in a Subpopulation of Bone Marrow-Derived Cells to Predict Retinal Neovascularization. 2020-10-20 10.1021/acschembio.0c00662 view
Swanson Acta Neuropathol Commun Identification of a dysfunctional microglial population in human Alzheimer's disease cortex using novel single-cell histology image analysis. 2020-10-20 10.1186/s40478-020-01047-9 view
Kapitansky Cells Single Cell ADNP Predictive of Human Muscle Disorders: Mouse Knockdown Results in Muscle Wasting. 2020-10-19 10.3390/cells9102320 view
Cambien PLoS Pathog Identification of oncolytic vaccinia restriction factors in canine high-grade mammary tumor cells using single-cell transcriptomics. 2020-10-19 10.1371/journal.ppat.1008660 view
Zhang Nat Commun Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development. 2020-10-19 10.1038/s41467-020-19012-4 view
Rodriques Nat Biotechnol RNA timestamps identify the age of single molecules in RNA sequencing. 2020-10-19 10.1038/s41587-020-0704-z view
Brbić Nat Methods MARS: discovering novel cell types across heterogeneous single-cell experiments. 2020-10-19 10.1038/s41592-020-00979-3 view
Amann-Zalcenstein Nat Immunol A new lymphoid-primed progenitor marked by Dach1 downregulation identified with single cell multi-omics. 2020-10-19 10.1038/s41590-020-0799-x view
Yang J Leukoc Biol Single-cell transcriptomics uncover distinct innate and adaptive cell subsets during tissue homeostasis and regeneration. 2020-10-18 10.1002/JLB.6MR0720-131R view
Lam J Am Heart Assoc Single-Cell Transcriptomics of Engineered Cardiac Tissues From Patient-Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes Reveals Abnormal Developmental Trajectory and Intrinsic Contractile Defects in Hypoplastic Right Heart Syndrome. 2020-10-16 10.1161/JAHA.120.016528 view
Wu Cardiovasc Res Angiogenesis After Acute Myocardial Infarction. 2020-10-16 10.1093/cvr/cvaa287 view
Schmidt Genes (Basel) Developmental scRNAseq Trajectories in Gene- and Cell-State Space-The Flatworm Example. 2020-10-16 10.3390/genes11101214 view
Bulut Arterioscler Thromb Vasc Biol KLF4 (Kruppel-Like Factor 4)-Dependent Perivascular Plasticity Contributes to Adipose Tissue inflammation. 2020-10-15 10.1161/ATVBAHA.120.314703 view
Borst Brain Pathol Deciphering the heterogeneity of myeloid cells during neuroinflammation in the single cell era. 2020-10-15 10.1111/bpa.12910 view
Fernández-Zapata Brain Pathol The use and limitations of single-cell mass cytometry for studying human microglia function. 2020-10-15 10.1111/bpa.12909 view
Tomar J Allergy Clin Immunol IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy. 2020-10-15 10.1016/j.jaci.2020.08.043 view
Kang Nat Biotechnol Author Correction: Multiplexed droplet single-cell RNA-sequencing using natural genetic variation. 2020-10-14 10.1038/s41587-020-0715-9 view
Pool Nature The cellular basis of distinct thirst modalities. 2020-10-14 10.1038/s41586-020-2821-8 view
Song Nature Cell-type-specific 3D epigenomes in the developing human cortex. 2020-10-14 10.1038/s41586-020-2825-4 view
Kim Korean J Intern Med Single-cell transcriptomics: a new research technique for precision medicine in nephrology. 2020-10-14 10.3904/kjim.2020.415 view
Hughes Immunity Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies. 2020-10-13 10.1016/j.immuni.2020.09.015 view
Fernandes Cell Rep Single-Cell Transcriptomics of Parkinson's Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses. 2020-10-13 10.1016/j.celrep.2020.108263 view
Panico Cardiovasc Res Defining circulating mononuclear cells in heart failure through single-cell RNA sequencing: new insights for an old disease. 2020-10-13 10.1093/cvr/cvaa156 view
Cooney Genome Biol Evol Single cell transcriptomics of ABEDINIUM reveals a new early-branching dinoflagellate lineage. 2020-10-12 10.1093/gbe/evaa196 view
Galletti Nat Immunol Two subsets of stem-like CD8+ memory T cell progenitors with distinct fate commitments in humans. 2020-10-12 10.1038/s41590-020-0791-5 view
Soon Nat Immunol Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory. 2020-10-12 10.1038/s41590-020-0800-8 view
Liu Nat Protoc Jointly defining cell types from multiple single-cell datasets using LIGER. 2020-10-12 10.1038/s41596-020-0391-8 view
Hie Cell Syst Leveraging Uncertainty in Machine Learning Accelerates Biological Discovery and Design. 2020-10-10 10.1016/j.cels.2020.09.007 view
Wang Int J Hematol Transcriptional heterogeneity of clonal plasma cells and immune evasion in immunoglobulin light chain amyloidosis. 2020-10-10 10.1007/s12185-020-03016-3 view
Aschenbrenner Gut Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance. 2020-10-09 10.1136/gutjnl-2020-321731 view
Sage Sci Rep Assessment of long non-coding RNA expression reveals novel mediators of the lung tumour immune response. 2020-10-09 10.1038/s41598-020-73787-6 view
Chattopadhyay Arterioscler Thromb Vasc Biol Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response. 2020-10-08 10.1161/ATVBAHA.120.315164 view
Xu Curr Osteoporos Rep The Effects of Calcitonin Gene-Related Peptide on Bone Homeostasis and Regeneration. 2020-10-08 10.1007/s11914-020-00624-0 view
Summers PLoS Biol Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system. 2020-10-08 10.1371/journal.pbio.3000859 view
Ma Mol Cancer Identification of a distinct luminal subgroup diagnosing and stratifying early stage prostate cancer by tissue-based single-cell RNA sequencing. 2020-10-08 10.1186/s12943-020-01264-9 view
Di Campli Eur Respir J The mononuclear phagocyte system contributes to fibrosis in post-transplant Obliterans Bronchiolitis. 2020-10-08 10.1183/13993003.00344-2020 view
Yao Nat Commun AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma. 2020-10-08 10.1038/s41467-020-18762-5 view
Chen Nat Commun Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma. 2020-10-08 10.1038/s41467-020-18916-5 view
Xiong Nat Commun A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response. 2020-10-08 10.1038/s41467-020-18546-x view
Shinozawa Gastroenterology High-Fidelity Drug Induced Liver Injury Screen Using Human PSC-derived Organoids. 2020-10-08 10.1053/j.gastro.2020.10.002 view
Li J Allergy Clin Immunol Single Cell Transcriptomic Analysis Reveals Key Immune Cell Phenotypes in the lung of Asthma Exacerbation. 2020-10-08 10.1016/j.jaci.2020.09.032 view
Xu Methods Ensemble learning models that predict surface protein abundance from single-cell multimodal omics data. 2020-10-08 10.1016/j.ymeth.2020.10.001 view
Mevel Elife RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development. 2020-10-07 10.7554/eLife.60225 view
Wang IEEE/ACM Trans Comput Biol Bioinform Single-cell RNA Sequencing Data Clustering by Low-Rank Subspace Ensemble Framework. 2020-10-07 10.1109/TCBB.2020.3029187 view
Wang BMC Bioinformatics Impact of data preprocessing on cell-type clustering based on single-cell RNA-seq data. 2020-10-07 10.1186/s12859-020-03797-8 view
Kok Oncogenesis Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors. 2020-10-07 10.1038/s41389-020-00270-2 view
Li Nature Microglia-organized scar-free spinal cord repair in neonatal mice. 2020-10-07 10.1038/s41586-020-2795-6 view
Kobayashi J Autoimmun Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis. 2020-10-07 10.1016/j.jaut.2020.102547 view
Hong Am J Respir Crit Care Med Single-cell Study of Two Rat Models of Pulmonary Arterial Hypertension Reveals Connections to Human Pathobiology and Drug Repositioning. 2020-10-06 10.1164/rccm.202006-2169OC view
Zhu Cell Death Dis Mesenchymal stem cells alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of Ly6C+ CD8+ T cells. 2020-10-06 10.1038/s41419-020-03036-1 view
Hou Nat Commun Predicting cell-to-cell communication networks using NATMI. 2020-10-06 10.1038/s41467-020-18873-z view
Kim Cell Rep Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies. 2020-10-06 10.1016/j.celrep.2020.108222 view
Wang Eur J Pharmacol Tissue distributions of antiviral drugs affect their capabilities of reducing viral loads in COVID-19 treatment. 2020-10-06 10.1016/j.ejphar.2020.173634 view
Li Stem Cell Reports Single-Cell RNA-Seq Reveals that CD9 Is a Negative Marker of Glucose-Responsive Pancreatic β-like Cells Derived from Human Pluripotent Stem Cells. 2020-10-06 10.1016/j.stemcr.2020.09.009 view
Carretta Int J Mol Sci Genomic Analysis of Hematopoietic Stem Cell at the Single-Cell Level: Optimization of Cell Fixation and Whole Genome Amplification (WGA) Protocol. 2020-10-06 10.3390/ijms21197366 view
Li Circulation Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue. 2020-10-06 10.1161/CIRCULATIONAHA.120.046528 view
Yasumizu Bioinformatics VIRTUS: a pipeline for comprehensive virus analysis from conventional RNA-seq data. 2020-10-05 10.1093/bioinformatics/btaa859 view
Deng Nat Med Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas. 2020-10-05 10.1038/s41591-020-1061-7 view
Darden Shock Single Cell RNA-SEQ of Human Myeloid Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets with Unique Transcriptional Responses: A Pilot Study. 2020-10-05 10.1097/SHK.0000000000001671 view
Men Prospects for Use of Single-Cell Sequencing to Assess DNA Methylation in Asthma. 2020-10-03 10.12659/MSM.925514 view
Zhao SC2disease: a manually curated database of single-cell transcriptome for human diseases. 2020-10-03 10.1093/nar/gkaa838 view
Hémon Biochem Biophys Res Commun SLC7A11 as a biomarker and therapeutic target in HPV-positive head and neck Squamous Cell Carcinoma. 2020-10-03 10.1016/j.bbrc.2020.09.134 view
Zhao Generation of cortical neurons through large-scale expanding neuroepithelial stem cell from human pluripotent stem cells. 2020-10-02 10.1186/s13287-020-01939-6 view
Wu EMBO J. Stromal cell diversity associated with immune evasion in human triple-negative breast cancer. 2020-10-01 10.15252/embj.2019104063 view
Yilmaz Mol Syst Biol Modeling tissue-relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels. 2020-10-01 10.15252/msb.20209649 view
Venkatakrishnan Cell Death Discov Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2. 2020-10-01 10.1038/s41420-020-00321-y view
Kim Hepatol Commun Functionally Diverse Inflammatory Responses in Peripheral and Liver Monocytes in Alcohol-Associated Hepatitis. 2020-10-01 10.1002/hep4.1563 view
Kadota Front Genet Commentary: A Systematic Evaluation of Single Cell RNA-Seq Analysis Pipelines. 2020-10-01 10.3389/fgene.2020.00941 view
Wu PeerJ A robust semi-supervised NMF model for single cell RNA-seq data. 2020-10-01 10.7717/peerj.10091 view
Ray Brain Behav Immun A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction. 2020-10-01 10.1016/j.bbi.2020.05.078 view
Qiu Massively parallel and time-resolved RNA sequencing in single cells with scNT-seq. 2020-10-01 10.1038/s41592-020-0935-4 view
Kalinich Recent Results Cancer Res. Quantitative Analysis of Circulating Tumor Cells Using RNA-Based Digital Scoring. 2020-10-01 10.1007/978-3-030-26439-0_4 view
Yosef PLoS One Isolation and transcriptional characterization of mouse perivascular astrocytes. 2020-10-01 10.1371/journal.pone.0240035 view
Nagaoka J Immunother Cancer Deep immunophenotyping at the single-cell level identifies a combination of anti-IL-17 and checkpoint blockade as an effective treatment in a preclinical model of data-guided personalized immunotherapy. 2020-10-01 10.1136/jitc-2020-001358 view
Weber PhyDOSE: Design of follow-up single-cell sequencing experiments of tumors. 2020-10-01 10.1371/journal.pcbi.1008240 view
Zhang Imputing single-cell RNA-seq data by considering cell heterogeneity and prior expression of dropouts. 2020-10-01 10.1093/jmcb/mjaa052 view
Patruno A review of computational strategies for denoising and imputation of single-cell transcriptomic data. 2020-10-01 10.1093/bib/bbaa222 view
Wu Comput Struct Biotechnol J Joint learning of multiple gene networks from single-cell gene expression data. 2020-10-01 10.1016/j.csbj.2020.09.004 view
Qi A spectral clustering with self-weighted multiple kernel learning method for single-cell RNA-seq data. 2020-10-01 10.1093/bib/bbaa216 view
Ramamoorthy EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism. 2020-10-01 10.1101/gad.340216.120 view
Zerrouk Identification of putative master regulators in rheumatoid arthritis synovial fibroblasts using gene expression data and network inference. 2020-10-01 10.1038/s41598-020-73147-4 view
Ibrahim Front Oncol Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. 2020-10-01 10.3389/fonc.2020.569985 view
Osborne Defining the First Part of the Oncogenic KRAS Journey. 2020-10-01 10.1016/j.stem.2020.09.009 view
Li Front Med (Lausanne) Evaluating Distribution and Prognostic Value of New Tumor-Infiltrating Lymphocytes in HCC Based on a scRNA-Seq Study With CIBERSORTx. 2020-10-01 10.3389/fmed.2020.00451 view
Attaf Front Immunol Corrigendum: FB5P-seq: FACS-Based 5-Prime End Single-Cell RNA-seq for Integrative Analysis of Transcriptome and Antigen Receptor Repertoire in B and T Cells. 2020-10-01 10.3389/fimmu.2020.02047 view
Li Front Immunol The Regulation of Exosome-Derived miRNA on Heterogeneity of Macrophages in Atherosclerotic Plaques. 2020-10-01 10.3389/fimmu.2020.02175 view
Wu Front Immunol Human Liver Macrophage Subsets Defined by CD32. 2020-10-01 10.3389/fimmu.2020.02108 view
Milichko Front Cell Dev Biol Novel Glial Cell Functions: Extensive Potency, Stem Cell-Like Properties, and Participation in Regeneration and Transdifferentiation. 2020-10-01 10.3389/fcell.2020.00809 view
Xu Cell Discov The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing. 2020-10-01 10.1038/s41421-020-00225-2 view
Kobak Mach Learn Knowl Discov Databases Heavy-tailed kernels reveal a finer cluster structure in t-SNE visualisations. 2020-10-01 10.1007/978-3-030-46150-8_8 view
Ebert Clin Transl Immunology Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy. 2020-10-01 10.1002/cti2.1191 view
Lu Cell Discov Single-cell transcriptome atlas of lung adenocarcinoma featured with ground glass nodules. 2020-10-01 10.1038/s41421-020-00200-x view
Teschendorff NPJ Genom Med Improved detection of tumor suppressor events in single-cell RNA-Seq data. 2020-10-01 10.1038/s41525-020-00151-y view
Li J Mol Cell Biol A new bioinformatics tool to recover missing gene expression in single-cell RNA sequencing data. 2020-09-30 10.1093/jmcb/mjaa053 view
Zhao Cancer Res. Transient activation of the Hedgehog-Gli pathway rescues radiotherapy-induced dry mouth via recovering salivary gland resident macrophages. 2020-09-30 10.1158/0008-5472.CAN-20-0503 view
Syage J. Virol. Single-cell RNA sequencing reveals the diversity of the immunological landscape following CNS infection by a murine coronavirus. 2020-09-30 10.1128/JVI.01295-20 view
Thrupp Cell Rep Single-Nucleus RNA-Seq Is Not Suitable for Detection of Microglial Activation Genes in Humans. 2020-09-29 10.1016/j.celrep.2020.108189 view
Wolf Circulation Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B100-Reactive CD4+ T-Regulatory Cells. 2020-09-29 10.1161/CIRCULATIONAHA.119.042863 view
Wong Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses. 2020-09-29 10.1016/j.immuni.2020.09.001 view
Lin Genome Med Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions. 2020-09-29 10.1186/s13073-020-00776-9 view
Van Buren Genet. Epidemiol. TWO-SIGMA: A novel two-component single cell model-based association method for single-cell RNA-seq data. 2020-09-29 10.1002/gepi.22361 view
Phan Elife Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate wounds. 2020-09-29 10.7554/eLife.60066 view
Gyllborg Nucleic Acids Res. Hybridization-based in situ sequencing (HybISS) for spatially resolved transcriptomics in human and mouse brain tissue. 2020-09-29 10.1093/nar/gkaa792 view
Depuydt Circ. Res. Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics. 2020-09-28 10.1161/CIRCRESAHA.120.316770 view
Vazquez-Armendariz EMBO J. Multilineage murine stem cells generate complex organoids to model distal lung development and disease. 2020-09-28 10.15252/embj.2019103476 view
Song The HDAC Inhibitor Domatinostat Promotes Cell Cycle Arrest, Induces Apoptosis and Increases Immunogenicity of Merkel Cell Carcinoma Cells. 2020-09-28 10.1016/j.jid.2020.08.023 view
Courtney Small Bowel Resection Increases Paracellular Gut Barrier Permeability via Alterations of Tight Junction Complexes Mediated by Intestinal TLR4. 2020-09-28 10.1016/j.jss.2020.08.049 view
Kalra PLoS Genet. Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty. 2020-09-28 10.1371/journal.pgen.1009025 view
Hu Proc. Natl. Acad. Sci. U.S.A. Genetic landscape and autoimmunity of monocytes in developing Vogt-Koyanagi-Harada disease. 2020-09-28 10.1073/pnas.2002476117 view
Schumann Nat. Immunol. Functional CRISPR dissection of gene networks controlling human regulatory T cell identity. 2020-09-28 10.1038/s41590-020-0784-4 view
Jiang Expert Rev Respir Med Recent developments in the pathobiology of lung myofibroblasts. 2020-09-27 10.1080/17476348.2021.1829972 view
Ruiz-Villalba Circulation Single-Cell RNA-seq Analysis Reveals a Crucial Role for Collagen Triple Helix Repeat Containing 1 (CTHRC1) Cardiac Fibroblasts after Myocardial Infarction. 2020-09-25 10.1161/CIRCULATIONAHA.119.044557 view
Wendt Science A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding. 2020-09-25 10.1126/science.abb7709 view
Wang Signal Transduct Target Ther Nanoparticle enhanced combination therapy for stem-like progenitors defined by single-cell transcriptomics in chemotherapy-resistant osteosarcoma. 2020-09-25 10.1038/s41392-020-00248-x view
Cosgrove Hum. Mol. Genet. Genes influenced by MEF2C contribute to neurodevelopmental disease via gene expression changes that affect multiple types of cortical excitatory neurons. 2020-09-25 10.1093/hmg/ddaa213 view
Sun Bioinformatics BP4RNAseq: a babysitter package for retrospective and newly generated RNA-seq data analyses using both alignment-based and alignment-free quantification method. 2020-09-25 10.1093/bioinformatics/btaa832 view
Song Nucleic Acids Res. STAB: a spatio-temporal cell atlas of the human brain. 2020-09-25 10.1093/nar/gkaa762 view
Partel FEBS J. Spage2vec: Unsupervised representation of localized spatial gene expression signatures. 2020-09-25 10.1111/febs.15572 view
Feng Stem Cell Res Ther Immunosuppressive effects of mesenchymal stem cells on lung B cell gene expression in LPS-induced acute lung injury. 2020-09-25 10.1186/s13287-020-01934-x view
Conway J. Am. Soc. Nephrol. Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease. 2020-09-25 10.1681/ASN.2020060806 view
Milner Proc. Natl. Acad. Sci. U.S.A. Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population. 2020-09-25 10.1073/pnas.2008571117 view
Verrillo J. Neurosci. Methods A reliable strategy for single-cell RNA sequencing analysis using cryoconserved primary cortical cells. 2020-09-25 10.1016/j.jneumeth.2020.108960 view
Dangi JCI Insight Single-cell transcriptomics of mouse kidney transplants reveals a myeloid cell pathway for transplant rejection. 2020-09-24 10.1172/jci.insight.141321 view
Castagnola Genome Res. Agonist-induced Functional Analysis and Cell Sorting coupled with single-cell transcriptomics characterizes cell subtypes in normal and pathological brain. 2020-09-24 10.1101/gr.262717.120 view
Bengtsson Gonzales Sci Rep Intrinsic electrophysiological properties predict variability in morphology and connectivity among striatal Parvalbumin-expressing Pthlh-cells. 2020-09-24 10.1038/s41598-020-72588-1 view
Sharma Cell Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma. 2020-09-24 10.1016/j.cell.2020.08.040 view
Smith-Edwards Gastroenterology Sympathetic input to multiple cell types in mouse and human colon produces region-specific responses. 2020-09-24 10.1053/j.gastro.2020.09.030 view
AbdelMassih Obes Med Single cell sequencing unraveling genetic basis of shared immunologic switch between Severe COVID19 and Obesity. 2020-09-24 10.1016/j.obmed.2020.100303 view
Zhang Exp. Cell Res. Single-cell transcriptome profiling reveals the mechanism of abnormal proliferation of epithelial cells in congenital cystic adenomatoid malformation. 2020-09-23 10.1016/j.yexcr.2020.112299 view
Pan Circulation Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human. 2020-09-23 10.1161/CIRCULATIONAHA.120.048378 view
Gandhi Elife Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration. 2020-09-23 10.7554/eLife.57779 view
Khazaei Cancer Discov H3.3G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in Giant Cell Tumour of Bone. 2020-09-23 10.1158/2159-8290.CD-20-0461 view
Magill Nat Commun Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma. 2020-09-23 10.1038/s41467-020-18582-7 view
Singh Cell Rep A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors. 2020-09-22 10.1016/j.celrep.2020.108175 view
Ni IEEE/ACM Trans Comput Biol Bioinform scLRTD : A novel low rank tensor decomposition method for imputing missing values in single-cell multi-omics sequencing data. 2020-09-22 10.1109/TCBB.2020.3025804 view
Xu BMC Genomics Multi-scale supervised clustering-based feature selection for tumor classification and identification of biomarkers and targets on genomic data. 2020-09-22 10.1186/s12864-020-07038-3 view
Ha Cell Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans. 2020-09-22 10.1016/j.cell.2020.09.009 view
Tian Methods Model-Based Autoencoders for Imputing Discrete single-cell RNA-seq Data. 2020-09-21 10.1016/j.ymeth.2020.09.010 view
Niu Genomics Single-cell RNA-seq reveals different subsets of non-specific cytotoxic cells in teleost. 2020-09-21 10.1016/j.ygeno.2020.09.031 view
Timshel Elife Genetic mapping of etiologic brain cell types for obesity. 2020-09-21 10.7554/eLife.55851 view
Abdelaal Nucleic Acids Res. SpaGE: Spatial Gene Enhancement using scRNA-seq. 2020-09-21 10.1093/nar/gkaa740 view
Wang Aging (Albany NY) Glioblastoma cell differentiation trajectory predicts the immunotherapy response and overall survival of patients. 2020-09-21 10.18632/aging.103695 view
Takeshima Clin Epigenetics Low-dose DNA demethylating therapy induces reprogramming of diverse cancer-related pathways at the single-cell level. 2020-09-21 10.1186/s13148-020-00937-y view
Ngo Proc. Natl. Acad. Sci. U.S.A. Circulating testican-2 is a podocyte-derived marker of kidney health. 2020-09-21 10.1073/pnas.2009606117 view
Penkava Nat Commun Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis. 2020-09-21 10.1038/s41467-020-18513-6 view
Beumer Nat. Rev. Mol. Cell Biol. Cell fate specification and differentiation in the adult mammalian intestine. 2020-09-21 10.1038/s41580-020-0278-0 view
Ortiz EBioMedicine Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract. 2020-09-21 10.1016/j.ebiom.2020.102976 view
Xia Hum. Reprod. Endosialin defines human stem Leydig cells with regenerative potential. 2020-09-20 10.1093/humrep/deaa174 view
Deng Breast Cancer Res. Treat. Serial single-cell profiling analysis of metastatic TNBC during Nab-paclitaxel and pembrolizumab treatment. 2020-09-19 10.1007/s10549-020-05936-4 view
Wang Emerg Microbes Infect An Atlas of Immune Cell Exhaustion in HIV-Infected Individuals Revealed by Single-Cell Transcriptomics. 2020-09-19 10.1080/22221751.2020.1826361 view
Burchill Cell Mol Gastroenterol Hepatol Oxidized Low-Density Lipoprotein drives dysfunction of the liver lymphatic system. 2020-09-19 10.1016/j.jcmgh.2020.09.007 view
Heavner Proc. Natl. Acad. Sci. U.S.A. Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes. 2020-09-18 10.1073/pnas.2008013117 view
Erickson AbSeq Protocol Using the Nano-Well Cartridge-Based Rhapsody Platform to Generate Protein and Transcript Expression Data on the Single-Cell Level. 2020-09-18 10.1016/j.xpro.2020.100092 view
Forte Protocol for Isolation of Cardiac Interstitial Cells from Adult Murine Hearts for Unbiased Single Cell Profiling. 2020-09-18 10.1016/j.xpro.2020.100077 view
Min Biochem. Biophys. Res. Commun. Phenotype-based single cell sequencing identifies diverse genetic subclones in CD133 positive cancer stem cells. 2020-09-18 10.1016/j.bbrc.2020.09.005 view
Zanini Sci Rep Northstar enables automatic classification of known and novel cell types from tumor samples. 2020-09-17 10.1038/s41598-020-71805-1 view
Fernandes Sci Rep Single-cell RNA-seq identifies unique transcriptional landscapes of human nucleus pulposus and annulus fibrosus cells. 2020-09-17 10.1038/s41598-020-72261-7 view
Mahalingam J. Cell. Physiol. Single-cell RNA sequencing analysis of SARS-CoV-2 entry receptors in human organoids. 2020-09-17 10.1002/jcp.30054 view
Cavagnero Ann. Allergy Asthma Immunol. Lipid-mediated innate lymphoid cell recruitment and activation in AERD. 2020-09-17 10.1016/j.anai.2020.09.011 view
Tan Curr. Opin. Cell Biol. A single-cell view of spermatogonial stem cells. 2020-09-17 10.1016/ view
Alsina Curr. Opin. Cell Biol. Mechanisms of cell specification and differentiation in vertebrate cranial sensory systems. 2020-09-17 10.1016/ view
Chen BMC Bioinformatics EnClaSC: a novel ensemble approach for accurate and robust cell-type classification of single-cell transcriptomes. 2020-09-17 10.1186/s12859-020-03679-z view
Van Phan Fixed single-cell RNA sequencing for understanding virus infection and host response. 2020-09-17 10.1101/2020.09.17.302232 view
Bamias Clin. Gastroenterol. Hepatol. Exploring the early phase of Crohn's disease. 2020-09-16 10.1016/j.cgh.2020.09.023 view
Nguyen Brief Bioinform A comprehensive survey of regulatory network inference methods using single-cell RNA sequencing data. 2020-09-16 10.1093/bib/bbaa190 view
Rai Sci Rep The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells. 2020-09-16 10.1038/s41598-020-72181-6 view
Liu Nature Reprogramming roadmap reveals route to human induced trophoblast stem cells. 2020-09-16 10.1038/s41586-020-2734-6 view
Li Wiley Interdiscip Rev Dev Biol Single-cell RNA sequencing in Drosophila: Technologies and applications. 2020-09-16 10.1002/wdev.396 view
Dong Cancer Cell Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma. 2020-09-15 10.1016/j.ccell.2020.08.014 view
Jacobs Exp. Hematol. Detection of chemotherapy-resistant patient-derived acute lymphoblastic leukemia clones in murine xenografts using cellular barcodes. 2020-09-15 10.1016/j.exphem.2020.09.188 view
Kashima Exp. Mol. Med. Single-cell sequencing techniques from individual to multiomics analyses. 2020-09-15 10.1038/s12276-020-00499-2 view
Panina Exp. Mol. Med. Human Cell Atlas and cell-type authentication for regenerative medicine. 2020-09-15 10.1038/s12276-020-0421-1 view
Fan Exp. Mol. Med. Single-cell transcriptomics in cancer: computational challenges and opportunities. 2020-09-15 10.1038/s12276-020-0422-0 view
Paik Circulation Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells. 2020-09-15 10.1161/CIRCULATIONAHA.119.041433 view
Bi Integr Biol (Camb) Tumor-on-a-chip platform to interrogate the role of macrophages in tumor progression. 2020-09-15 10.1093/intbio/zyaa017 view
Xu Stem Cells Single-cell profiling of lncRNAs and their cell lineage commitment roles via RNA-DNA-DNA triplex formation in mammary epithelium. 2020-09-15 10.1002/stem.3274 view
Chen Lab Chip μCB-seq: microfluidic cell barcoding and sequencing for high-resolution imaging and sequencing of single cells. 2020-09-15 10.1039/d0lc00169d view
Encarnação Mol Genet Genomic Med NPC1 silent variant induces skipping of exon 11 (p.V562V) and unfolded protein response was found in a specific Niemann-Pick type C patient. 2020-09-15 10.1002/mgg3.1451 view
Jiang Clin. Exp. Allergy Gene signatures from scRNA-seq accurately quantify mast cells in biopsies in asthma. 2020-09-15 10.1111/cea.13732 view
Helmke Eur. J. Immunol. Peritoneal dialysate-range hypertonic glucose promotes T cell IL-17 production that induces mesothelial inflammation. 2020-09-14 10.1002/eji.202048733 view
Guo BMC Genomics RNA-seq analysis of galaninergic neurons from ventrolateral preoptic nucleus identifies expression changes between sleep and wake. 2020-09-14 10.1186/s12864-020-07050-7 view
Ravenscroft J. Neurosci. Drosophila voltage-gated sodium channels are only expressed in active neurons and are localized to distal axonal initial segment-like domains. 2020-09-14 10.1523/JNEUROSCI.0142-20.2020 view
Song bioRxiv Immunologically distinct responses occur in the CNS of COVID-19 patients. 2020-09-12 10.1101/2020.09.11.293464 view
Hwang Wiley Interdiscip Rev Syst Biol Med The shifting shape and functional specializations of the cell cycle during lineage development. 2020-09-11 10.1002/wsbm.1504 view
Weinberger Nat Commun Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation. 2020-09-11 10.1038/s41467-020-18287-x view
Kalra Commun Biol Analysis of single-cell transcriptomes links enrichment of olfactory receptors with cancer cell differentiation status and prognosis. 2020-09-11 10.1038/s42003-020-01232-5 view
Omori Cell Metab. Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo. 2020-09-11 10.1016/j.cmet.2020.09.006 view
Zarinsefat bioRxiv Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation. 2020-09-11 10.1101/2020.09.11.281782 view
Radtke Mol Ther Methods Clin Dev Purification of Human CD34+CD90+ HSCs Reduces Target Cell Population and Improves Lentiviral Transduction for Gene Therapy. 2020-09-11 10.1016/j.omtm.2020.07.010 view
Parker Cell Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies. 2020-09-11 10.1016/j.cell.2020.08.022 view
Nguyen Cancer Immunol. Immunother. Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma. 2020-09-11 10.1007/s00262-020-02713-6 view
Zhang Cell Oncol (Dordr) 1p/19q co-deletion status is associated with distinct tumor-associated macrophage infiltration in IDH mutated lower-grade gliomas. 2020-09-11 10.1007/s13402-020-00561-1 view
Akiba Curr. Opin. Gastroenterol. Duodenal chemosensory system: enterocytes, enteroendocrine cells, and tuft cells. 2020-09-10 10.1097/MOG.0000000000000685 view
Huang Genome Biol. Natural display of nuclear-encoded RNA on the cell surface and its impact on cell interaction. 2020-09-10 10.1186/s13059-020-02145-6 view
McAndrews EMBO J. A map of human breast cancer: new players in stromal-immune crosstalk. 2020-09-10 10.15252/embj.2020106368 view
Shankar Kidney Int. Human kidney organoids produce functional renin. 2020-09-09 10.1016/j.kint.2020.08.008 view
Dadaneh BMC Genomics Bayesian gamma-negative binomial modeling of single-cell RNA sequencing data. 2020-09-09 10.1186/s12864-020-06938-8 view
Chen Am. J. Physiol., Cell Physiol. Heterogeneous groups of alveolar type II cells in lung homeostasis and repair. 2020-09-09 10.1152/ajpcell.00341.2020 view
Tran PLoS Comput. Biol. Tempora: Cell trajectory inference using time-series single-cell RNA sequencing data. 2020-09-09 10.1371/journal.pcbi.1008205 view
Griss Mol. Cell Proteomics ReactomeGSA - Efficient Multi-Omics Comparative Pathway Analysis. 2020-09-09 10.1074/mcp.TIR120.002155 view
Schlesinger Nat Commun Single-cell transcriptomes of pancreatic preinvasive lesions and cancer reveal acinar metaplastic cells' heterogeneity. 2020-09-09 10.1038/s41467-020-18207-z view
Palikuqi Nature Adaptable haemodynamic endothelial cells for organogenesis and tumorigenesis. 2020-09-09 10.1038/s41586-020-2712-z view
Maiuri Neuron Single Cell Technologies Define New Therapeutic Avenues for Huntington's Disease. 2020-09-09 10.1016/j.neuron.2020.08.007 view
Wen PLoS Comput. Biol. VALERIE: Visual-based inspection of alternative splicing events at single-cell resolution. 2020-09-08 10.1371/journal.pcbi.1008195 view
Cho Nat Commun Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila. 2020-09-08 10.1038/s41467-020-18135-y view
Bagnall Cell Syst Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling. 2020-09-07 10.1016/j.cels.2020.08.007 view
Wang J. Cell Biol. Different lineage contexts direct common pro-neural factors to specify distinct retinal cell subtypes. 2020-09-07 10.1083/jcb.202003026 view
Voigt Exp. Eye Res. Spectacle: An interactive resource for ocular single-cell RNA sequencing data analysis. 2020-09-07 10.1016/j.exer.2020.108204 view
Wang J. Exp. Med. Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model. 2020-09-07 10.1084/jem.20200785 view
Baron Cell Syst The Stress-Like Cancer Cell State Is a Consistent Component of Tumorigenesis. 2020-09-05 10.1016/j.cels.2020.08.018 view
Arunachalam Science Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans. 2020-09-04 10.1126/science.abc6261 view
Teschendorff Genome Biol. EPISCORE: cell type deconvolution of bulk tissue DNA methylomes from single-cell RNA-Seq data. 2020-09-04 10.1186/s13059-020-02126-9 view
Wang Science Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates. 2020-09-04 10.1126/science.aaz3090 view
Chan Circulation Prioritizing Candidates of Post-Myocardial Infarction Heart Failure Using Plasma Proteomics and Single-Cell Transcriptomics. 2020-09-04 10.1161/CIRCULATIONAHA.119.045158 view
Davis JCI Insight Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair. 2020-09-03 10.1172/jci.insight.138443 view
Zhao Blood Tumor intrinsic and extrinsic determinants of response to blinatumomab in adults with B-ALL. 2020-09-03 10.1182/blood.2020006287 view
Chen J. Am. Soc. Nephrol. Two Tales of Single-Cell RNA Sequencing: Gene Expression and Alternative Splicing in Mouse Kidney Development. 2020-09-03 10.1681/ASN.2020081180 view
Pei Cell Stem Cell Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding. 2020-09-03 10.1016/j.stem.2020.07.018 view
Keyvani Chahi Cell Stem Cell Hematopoiesis in High Definition: Combining State and Fate Mapping. 2020-09-03 10.1016/j.stem.2020.08.010 view
Mi Chin. Med. J. Application of single-cell sequencing in autoimmune diseases. 2020-09-03 10.1097/CM9.0000000000001050 view
Meyer Gastroenterology Group 2 innate lymphoid cells coordinate damage response in the stomach. 2020-09-03 10.1053/j.gastro.2020.08.051 view
Zaccaria Nat. Biotechnol. Characterizing allele- and haplotype-specific copy numbers in single cells with CHISEL. 2020-09-02 10.1038/s41587-020-0661-6 view
Min iScience p63 and Its Target Follistatin Maintain Salivary Gland Stem/Progenitor Cell Function through TGF-β/Activin Signaling. 2020-09-02 10.1016/j.isci.2020.101524 view
Huo Front Med Effects of vitrification and cryostorage duration on single-cell RNA-Seq profiling of vitrified-thawed human metaphase II oocytes. 2020-09-02 10.1007/s11684-020-0792-7 view
Postlethwait bioRxiv An intestinal cell type in zebrafish is the nexus for the SARS-CoV-2 receptor and the Renin-Angiotensin-Aldosterone System that contributes to COVID-19 comorbidities. 2020-09-02 10.1101/2020.09.01.278366 view
Wen Am. J. Respir. Crit. Care Med. In Vivo Generation of Lung and Thyroid Tissues from Embryonic Stem Cells using Blastocyst Complementation. 2020-09-02 10.1164/rccm.201909-1836OC view
Mentkowski Am. J. Physiol., Cell Physiol. Monocyte recruitment and fate specification after myocardial infarction. 2020-09-02 10.1152/ajpcell.00330.2020 view
De Micheli Am. J. Physiol., Cell Physiol. Single-cell Transcriptomic Analyses Identifies Extensive Heterogeneity in the Cellular Composition of Mouse Achilles Tendons. 2020-09-02 10.1152/ajpcell.00372.2020 view
Yazicioglu Am. J. Physiol. Lung Cell Mol. Physiol. Aging impairs alveolar epithelial type II cell function in acute lung injury. 2020-09-02 10.1152/ajplung.00093.2020 view
Son Cancer Immunol Res Tumor-Infiltrating Regulatory T Cell Accumulation in the Tumor Microenvironment is Mediated by IL33/ST2 Signaling. 2020-09-02 10.1158/2326-6066.CIR-19-0828 view
Sayols Development Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors. 2020-09-02 10.1242/dev.188839 view
Ariss J. Cell. Sci. Amalgam regulates the receptor tyrosine kinase pathway through Sprouty in glial cell development. 2020-09-02 10.1242/jcs.250837 view
Xing Sci Adv Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing. 2020-09-01 10.1126/sciadv.aba1190 view
Han Methods Mol. Biol. The Adaptome as Biomarker for Assessing Cancer Immunity and Immunotherapy. 2020-09-01 10.1007/978-1-4939-9773-2_17 1 view
Zhang Front Genet Single Cell RNA-seq Data Analysis Reveals the Potential Risk of SARS-CoV-2 Infection Among Different Respiratory System Conditions. 2020-09-01 10.3389/fgene.2020.00942 view
Ashary Front Cell Dev Biol Single-Cell RNA-seq Identifies Cell Subsets in Human Placenta That Highly Expresses Factors Driving Pathogenesis of SARS-CoV-2. 2020-09-01 10.3389/fcell.2020.00783 view
Ren Comput Biol Chem L2,1-Extreme Learning Machine: An Efficient Robust Classifier for Tumor Classification. 2020-09-01 10.1016/j.compbiolchem.2020.107368 view
Das Cancers (Basel) Cancer-Specific Immune Prognostic Signature in Solid Tumors and Its Relation to Immune Checkpoint Therapies. 2020-09-01 10.3390/cancers12092476 view
Zhang Nat. Immunol. Single-cell landscape of immunological responses in patients with COVID-19. 2020-09-01 10.1038/s41590-020-0762-x view
Yu Adv. Exp. Med. Biol. Understanding Diseases from Single-Cell Sequencing and Methylation. 2020-09-01 10.1007/978-981-15-4494-1_1 view
Pensold Adv. Exp. Med. Biol. Methods for Single-Cell Isolation and Preparation. 2020-09-01 10.1007/978-981-15-4494-1_2 1 view
Pang Cancer Manag Res S1PR2 Knockdown Promotes Migration and Invasion in Multiple Myeloma Cells via NF-κB Activation. 2020-09-01 10.2147/CMAR.S237330 view
Gupta Adv. Exp. Med. Biol. Single-Cell Sequencing of T cell Receptors: A Perspective on the Technological Development and Translational Application. 2020-09-01 10.1007/978-981-15-4494-1_3 view
Wu Adv. Exp. Med. Biol. Single Cell Sequencing: A New Dimension in Cancer Diagnosis and Treatment. 2020-09-01 10.1007/978-981-15-4494-1_9 view
Savulescu Front Mol Biosci Pinpointing Cell Identity in Time and Space. 2020-09-01 10.3389/fmolb.2020.00209 view
Luo Adv. Exp. Med. Biol. Application of Single-Cell RNA Sequencing in Pancreatic Cancer and the Endocrine Pancreas. 2020-09-01 10.1007/978-981-15-4494-1_12 view
Murphy Adv. Exp. Med. Biol. Single-Cell Sequencing in Genitourinary Malignancies. 2020-09-01 10.1007/978-981-15-4494-1_13 view
Bagger Adv. Exp. Med. Biol. Single Cell Sequencing in Cancer Diagnostics. 2020-09-01 10.1007/978-981-15-4494-1_15 view
Garcia Adv. Exp. Med. Biol. Single Cell RNA Sequencing in Human Disease: Renal, Pancreatic, and Viral Diseases. 2020-09-01 10.1007/978-981-15-4494-1_16 view
Singh Adv. Exp. Med. Biol. Single-Cell Sequencing in Human Genital Infections. 2020-09-01 10.1007/978-981-15-4494-1_17 view
Chang Adv. Exp. Med. Biol. Values of Single-Cell RNA Sequencing in Development of Cerebral Cortex. 2020-09-01 10.1007/978-981-15-4494-1_19 view
Chiffelle Curr. Opin. Biotechnol. T-cell repertoire analysis and metrics of diversity and clonality. 2020-09-01 10.1016/j.copbio.2020.07.010 view
Bounab Nat Protoc Dynamic single-cell phenotyping of immune cells using the microfluidic platform DropMap. 2020-09-01 10.1038/s41596-020-0354-0 view
Zhou Onco Targets Ther HSPA12B Secreted by Tumor-Associated Endothelial Cells Might Induce M2 Polarization of Macrophages via Activating PI3K/Akt/mTOR Signaling. 2020-09-01 10.2147/OTT.S254985 view
Healy Front Immunol Transcriptional Profiling of CD8+ CMV-Specific T Cell Functional Subsets Obtained Using a Modified Method for Isolating High-Quality RNA From Fixed and Permeabilized Cells. 2020-09-01 10.3389/fimmu.2020.01859 view
Park Front Immunol Re-analysis of Single Cell Transcriptome Reveals That the NR3C1-CXCL8-Neutrophil Axis Determines the Severity of COVID-19. 2020-09-01 10.3389/fimmu.2020.02145 view
Chiba Front Cell Dev Biol Single-Cell RNA-Sequencing From Mouse Incisor Reveals Dental Epithelial Cell-Type Specific Genes. 2020-09-01 10.3389/fcell.2020.00841 view
Paez J Open Source Softw scTree: An R package to generate antibody-compatible classifiers from single-cell sequencing data. 2020-09-01 10.21105/joss.02061 view
Qie Theranostics Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis. 2020-09-01 10.7150/thno.45614 view
Borcherding F1000Res scRepertoire: An R-based toolkit for single-cell immune receptor analysis. 2020-09-01 10.12688/f1000research.22139.2 view
Gustafsson PLoS ONE Sources of variation in cell-type RNA-Seq profiles. 2020-09-01 10.1371/journal.pone.0239495 view
Parikh J Immunother Cancer Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma. 2020-09-01 10.1136/jitc-2020-001048 view
Seirup PLoS ONE Reproducibility across single-cell RNA-seq protocols for spatial ordering analysis. 2020-09-01 10.1371/journal.pone.0239711 view
Mandrycky Sci Adv 3D curvature-instructed endothelial flow response and tissue vascularization. 2020-09-01 10.1126/sciadv.abb3629 view
Germain Genome Biol. pipeComp, a general framework for the evaluation of computational pipelines, reveals performant single cell RNA-seq preprocessing tools. 2020-09-01 10.1186/s13059-020-02136-7 view
O'Leary Elife Extensive and spatially variable within-cell-type heterogeneity across the basolateral amygdala. 2020-09-01 10.7554/eLife.59003 view
Kim Genomics Inform A semi-automatic cell type annotation method for single-cell RNA sequencing dataset. 2020-09-01 10.5808/GI.2020.18.3.e26 view
He Genome Biol. CSS: cluster similarity spectrum integration of single-cell genomics data. 2020-09-01 10.1186/s13059-020-02147-4 view
Shin Cell Rep Controlled Cycling and Quiescence Enables Efficient HDR in Engraftment-Enriched Adult Hematopoietic Stem and Progenitor Cells. 2020-09-01 10.1016/j.celrep.2020.108093 view
Kim Nat Commun The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development. 2020-08-31 10.1038/s41467-020-18231-z view
Lee Nat Commun Single-cell RNA sequencing identifies shared differentiation paths of mouse thymic innate T cells. 2020-08-31 10.1038/s41467-020-18155-8 view
Hoffman Cell Mol Gastroenterol Hepatol The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice. 2020-08-31 10.1016/j.jcmgh.2020.08.011 view
Lantz Sci Rep Single-cell RNA sequencing uncovers heterogenous transcriptional signatures in macrophages during efferocytosis. 2020-08-31 10.1038/s41598-020-70353-y view
Bonnay Cell Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis. 2020-08-30 10.1016/j.cell.2020.07.039 view
Suter Neurobiol. Dis. Epigenetic pathways and plasticity in brain tumors. 2020-08-30 10.1016/j.nbd.2020.105060 view
Zhou J. Mol. Cell. Cardiol. Reading the heart at single-cell resolution. 2020-08-29 10.1016/j.yjmcc.2020.08.010 view
Schmid J Pharmacol Toxicol Methods Characterization of iCell cardiomyocytes using single-cell RNA-sequencing methods. 2020-08-29 10.1016/j.vascn.2020.106915 view
Ramesh Proc. Natl. Acad. Sci. U.S.A. A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis. 2020-08-28 10.1073/pnas.2008523117 view
Manoranjan Nat Commun Wnt activation as a therapeutic strategy in medulloblastoma. 2020-08-28 10.1038/s41467-020-17953-4 view
Vandenbon Nat Commun A clustering-independent method for finding differentially expressed genes in single-cell transcriptome data. 2020-08-28 10.1038/s41467-020-17900-3 view
Januszyk Micromachines (Basel) Characterization of Diabetic and Non-Diabetic Foot Ulcers Using Single-Cell RNA-Sequencing. 2020-08-28 10.3390/mi11090815 view
Mohammed Int J Mol Sci Δ9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression. 2020-08-28 10.3390/ijms21176244 view
Hou Genome Biol. A systematic evaluation of single-cell RNA-sequencing imputation methods. 2020-08-27 10.1186/s13059-020-02132-x view
Yoda Microbiol Resour Announc High-Quality Draft Single-Cell Genome Sequences of Two Gammaproteobacteria Strains Sampled from Soil in a Strawberry Farm. 2020-08-27 10.1128/MRA.00743-20 view
McFarland Nat Commun Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action. 2020-08-27 10.1038/s41467-020-17440-w view
Aldridge Nat Commun Single cell transcriptomics comes of age. 2020-08-27 10.1038/s41467-020-18158-5 view
Han Nat Commun Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis. 2020-08-27 10.1038/s41467-020-17968-x view
Drag BMC Neurol A longitudinal study of the post-stroke immune response and cognitive functioning: the StrokeCog study protocol. 2020-08-26 10.1186/s12883-020-01897-9 view
McIntyre Proc. Natl. Acad. Sci. U.S.A. β2 Integrins differentially regulate γδ T cell subset thymic development and peripheral maintenance. 2020-08-26 10.1073/pnas.1921930117 view
Chen Int J Mol Sci Conventional Co-Housing Modulates Murine Gut Microbiota and Hematopoietic Gene Expression. 2020-08-26 10.3390/ijms21176143 view
Xi Elife m6A RNA methylation impacts fate choices during skin morphogenesis. 2020-08-26 10.7554/eLife.56980 view
Andreatta Bioinformatics STACAS: Sub-Type Anchor Correction for Alignment in Seurat to integrate single-cell RNA-seq data. 2020-08-26 10.1093/bioinformatics/btaa755 view
Park Cell Rep Single-Cell Transcriptome Analysis of Colon Cancer Cell Response to 5-Fluorouracil-Induced DNA Damage. 2020-08-25 10.1016/j.celrep.2020.108077 view
Sandu Cell Rep Landscape of Exhausted Virus-Specific CD8 T Cells in Chronic LCMV Infection. 2020-08-25 10.1016/j.celrep.2020.108078 view
Narayanan J Vis Exp Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq. 2020-08-25 10.3791/61542 view
Cho J Vis Exp Preparation of Adipose Progenitor Cells from Mouse Epididymal Adipose Tissues. 2020-08-25 10.3791/61694 view
Dibaeinia Cell Syst SERGIO: A Single-Cell Expression Simulator Guided by Gene Regulatory Networks. 2020-08-25 10.1016/j.cels.2020.08.003 view
Pham Brief. Bioinformatics The winning methods for predicting cellular position in the DREAM single-cell transcriptomics challenge. 2020-08-25 10.1093/bib/bbaa181 view
Yeo Elife Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer. 2020-08-25 10.7554/eLife.58810 view
Baran-Gale Elife Ageing compromises mouse thymus function and remodels epithelial cell differentiation. 2020-08-25 10.7554/eLife.56221 view
Osorio Bioinformatics Systematic determination of the mitochondrial proportion in human and mice tissues for single-cell RNA sequencing data quality control. 2020-08-25 10.1093/bioinformatics/btaa751 view
Eikmans HLA Got your mother in a whirl: the role of maternal T cells and myeloid cells in pregnancy. 2020-08-25 10.1111/tan.14055 view
Wang Nat Commun Single cell transcriptomics of human epidermis identifies basal stem cell transition states. 2020-08-25 10.1038/s41467-020-18075-7 view
Hossain Med Res Rev Reinvigorating exhausted CD8+ cytotoxic T lymphocytes in the tumor microenvironment and current strategies in cancer immunotherapy. 2020-08-25 10.1002/med.21727 view
Raimundo Genome Biol. Tuning parameters of dimensionality reduction methods for single-cell RNA-seq analysis. 2020-08-24 10.1186/s13059-020-02128-7 view
Lawson Elife An improved zebrafish transcriptome annotation for sensitive and comprehensive detection of cell type-specific genes. 2020-08-24 10.7554/eLife.55792 view
Li PLoS Comput. Biol. A novel single-cell based method for breast cancer prognosis. 2020-08-24 10.1371/journal.pcbi.1008133 view
Yuste Nat. Neurosci. A community-based transcriptomics classification and nomenclature of neocortical cell types. 2020-08-24 10.1038/s41593-020-0685-8 1 view
Holloway Dev. Cell Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells. 2020-08-24 10.1016/j.devcel.2020.07.023 view
Yang Theriogenology Single cell RNA-seq reveals molecular pathways altered by 7, 12-dimethylbenz[a]anthracene treatment on pig oocytes. 2020-08-21 10.1016/j.theriogenology.2020.08.020 view
Deng Brief. Bioinformatics LncAS2Cancer: a comprehensive database for alternative splicing of lncRNAs across human cancers. 2020-08-21 10.1093/bib/bbaa179 view
Meng Circulation A Reservoir of Fibroblasts Promotes Recovery from Limb Ischemia. 2020-08-21 10.1161/CIRCULATIONAHA.120.046872 view
Hao Hum. Mol. Genet. Integrative Analysis of scRNA-seq and GWAS Data Pinpoints Periportal Hepatocytes as the Relevant Liver Cell Types for Blood Lipids. 2020-08-21 10.1093/hmg/ddaa188 view
Brechbuhl Mol. Carcinog. Analysis of circulating breast cancer cell heterogeneity and interactions with peripheral blood mononuclear cells. 2020-08-21 10.1002/mc.23242 view
Ye Cells Detecting Interactive Gene Groups for Single-Cell RNA-Seq Data Based on Co-Expression Network Analysis and Subgraph Learning. 2020-08-21 10.3390/cells9091938 view
Maucourant Sci Immunol Natural killer cell immunotypes related to COVID-19 disease severity. 2020-08-21 10.1126/sciimmunol.abd6832 view
Mazzara Nat Commun Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neurons. 2020-08-21 10.1038/s41467-020-17954-3 view
Faure Nat Commun Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates. 2020-08-21 10.1038/s41467-020-17929-4 view
Bockerstett Gastroenterology Single Cell Transcriptional Analyses Identify Lineage-Specific Epithelial Responses to Inflammation and Metaplastic Development in the Gastric Corpus. 2020-08-21 10.1053/j.gastro.2020.08.027 view
Cutillo BMC Bioinformatics OscoNet: inferring oscillatory gene networks. 2020-08-21 10.1186/s12859-020-03561-y view
Rocha-Resende JCI Insight Developmental changes in myocardial B cells mirror changes in B cells associated with different organs. 2020-08-20 10.1172/jci.insight.139377 view
Hirata iScience The Brain Microenvironment Induces DNMT1 Suppression and Indolence of Metastatic Cancer Cells. 2020-08-20 10.1016/j.isci.2020.101480 view
Katzenelenbogen Cell Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer. 2020-08-20 10.1016/j.cell.2020.06.032 view
Molgora Cell TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy. 2020-08-20 10.1016/j.cell.2020.07.013 view
Banerjee Gastroenterology Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation. 2020-08-20 10.1053/j.gastro.2020.08.029 view
Vafadarnejad Circ. Res. Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction. 2020-08-19 10.1161/CIRCRESAHA.120.317200 view
Tong Virchows Arch. FOXI1 expression in chromophobe renal cell carcinoma and renal oncocytoma: a study of The Cancer Genome Atlas transcriptome-based outlier mining and immunohistochemistry. 2020-08-19 10.1007/s00428-020-02900-x view
Perillo Elife Regulation of dynamic pigment cell states at single-cell resolution. 2020-08-19 10.7554/eLife.60388 view
Mahadevaiah Nature A single-cell transcriptome atlas of marsupial embryogenesis and X inactivation. 2020-08-19 10.1038/s41586-020-2629-6 view
Zappia EMBO Rep. A cell atlas of adult muscle precursors uncovers early events in fibre-type divergence in Drosophila. 2020-08-19 10.15252/embr.201949555 view
Sekula BMC Bioinformatics A sparse Bayesian factor model for the construction of gene co-expression networks from single-cell RNA sequencing count data. 2020-08-18 10.1186/s12859-020-03707-y view
Francisco Fluids Barriers CNS Advancing brain barriers RNA sequencing: guidelines from experimental design to publication. 2020-08-18 10.1186/s12987-020-00207-2 view
Aubert Nat Commun Gene editing and elimination of latent herpes simplex virus in vivo. 2020-08-18 10.1038/s41467-020-17936-5 view
Foster Development A single cell RNA-seq resource for early sea urchin development. 2020-08-18 10.1242/dev.191528 view
Nip Genome Res. RNA-Bloom enables reference-free and reference-guided sequence assembly for single-cell transcriptomes. 2020-08-17 10.1101/gr.260174.119 view
Liddelow Trends Immunol. Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime? 2020-08-17 10.1016/ view
Garcia-Recio J. Clin. Invest. FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease. 2020-08-17 10.1172/JCI130323 view
Koenitzer Am. J. Respir. Cell Mol. Biol. Single Nucleus RNASeq Profiling of Mouse Lung: Reduced Dissociation Bias and Improved Rare Cell Type Detection Compared with Single Cell RNASeq. 2020-08-17 10.1165/rcmb.2020-0095MA view
Ciccolella Bioinformatics Inferring Cancer Progression from Single-Cell Sequencing while Allowing Mutation Losses. 2020-08-17 10.1093/bioinformatics/btaa722 view
Imdahl Nat Microbiol Single-cell RNA-sequencing reports growth-condition-specific global transcriptomes of individual bacteria. 2020-08-17 10.1038/s41564-020-0774-1 view
Guo Nat. Genet. Single-cell transcriptomics identifies a distinct luminal progenitor cell type in distal prostate invagination tips. 2020-08-17 10.1038/s41588-020-0642-1 view
Peics J Vis Exp Isolation of Adipogenic and Fibro-Inflammatory Stromal Cell Subpopulations from Murine Intra-Abdominal Adipose Depots. 2020-08-16 10.3791/61610 view
Hu Biochem. Biophys. Res. Commun. Single-cell RNA sequencing reveals the regenerative potential of thyroid follicular epithelial cells in metastatic thyroid carcinoma. 2020-08-15 10.1016/j.bbrc.2020.06.050 view
Wang Cancer Biol Med Single-cell RNA-seq reveals the immune escape and drug resistance mechanisms of mantle cell lymphoma. 2020-08-15 10.20892/j.issn.2095-3941.2020.0073 view
Nam Chemometr Intell Lab Syst hubViz: A Novel Tool for Hub-centric Visualization. 2020-08-15 10.1016/j.chemolab.2020.104071 view
Wang ACS Pharmacol Transl Sci SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral Epithelium. 2020-08-14 10.1021/acsptsci.0c00062 view
Li J Bioinform Comput Biol Single-cell RNA-seq data clustering: A survey with performance comparison study. 2020-08-14 10.1142/S0219720020400053 view
Zhao Cell Death Dis XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia-reperfusion injury. 2020-08-14 10.1038/s41419-020-02871-6 view
Hong Nat Commun Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi. 2020-08-14 10.1038/s41467-020-17886-y view
Conrad Commun Biol Maximizing transcription of nucleic acids with efficient T7 promoters. 2020-08-14 10.1038/s42003-020-01167-x view
Peterson Dis Model Mech Disturbed NO signalling gives rise to congenital bicuspid aortic valve and aortopathy. 2020-08-14 10.1242/dmm.044990 view
Wu Medicine (Baltimore) Identification of the key gene and pathways associated with osteoarthritis via single-cell RNA sequencing on synovial fibroblasts. 2020-08-14 10.1097/MD.0000000000021707 view
Zhou Nat Commun Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. 2020-08-13 10.1038/s41467-020-17890-2 view
Foster Nat Commun Elucidating the fundamental fibrotic processes driving abdominal adhesion formation. 2020-08-13 10.1038/s41467-020-17883-1 view
Aska iScience Single-Cell Sequencing of Mouse Thymocytes Reveals Mutational Landscape Shaped by Replication Errors, Mismatch Repair, and H3K36me3. 2020-08-13 10.1016/j.isci.2020.101452 view
Lodish Exp. Hematol. Over Sixty Years of Experimental Hematology (Without a License). 2020-08-13 10.1016/j.exphem.2020.08.005 view
Martyniuk Comp. Biochem. Physiol. B, Biochem. Mol. Biol. Perspectives on transcriptomics in animal physiology studies. 2020-08-13 10.1016/j.cbpb.2020.110490 view
Lebrigand Nat Commun High throughput error corrected Nanopore single cell transcriptome sequencing. 2020-08-12 10.1038/s41467-020-17800-6 view
Palla iScience Latent Factor Modeling of scRNA-Seq Data Uncovers Dysregulated Pathways in Autoimmune Disease Patients. 2020-08-12 10.1016/j.isci.2020.101451 view
Parekh Am. J. Physiol., Cell Physiol. Stem Cells and Lung Regeneration. 2020-08-12 10.1152/ajpcell.00036.2020 view
Liu Int J Mol Sci Visualizing Single-Cell RNA-seq Data with Semisupervised Principal Component Analysis. 2020-08-12 10.3390/ijms21165797 view
Gillen Cell Rep Single-Cell RNA Sequencing of Childhood Ependymoma Reveals Neoplastic Cell Subpopulations That Impact Molecular Classification and Etiology. 2020-08-11 10.1016/j.celrep.2020.108023 view
Zheng Protein Cell A human circulating immune cell landscape in aging and COVID-19. 2020-08-11 10.1007/s13238-020-00762-2 view
Chen Cell Rep Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling. 2020-08-11 10.1016/j.celrep.2020.108007 view
Tan Elife The role of the NMD factor UPF3B in olfactory sensory neurons. 2020-08-10 10.7554/eLife.57525 view
Scharer Nat Commun Antibody-secreting cell destiny emerges during the initial stages of B-cell activation. 2020-08-10 10.1038/s41467-020-17798-x view
Brandão J. Leukoc. Biol. Neuroinflammation at single cell level: What is new? 2020-08-10 10.1002/JLB.3MR0620-035R view
Lo Cancers (Basel) Single-Cell RNA-seq Reveals Obesity-Induced Alterations in the Brca1-Mutated Mammary Gland Microenvironment. 2020-08-10 10.3390/cancers12082235 view
Sun J. Clin. Endocrinol. Metab. Sexually dimorphic crosstalk at the maternal-fetal interface. 2020-08-09 10.1210/clinem/dgaa503 view
Shangguan Genomics Application of single-cell RNA sequencing in embryonic development. 2020-08-08 10.1016/j.ygeno.2020.08.007 view
Maynard Cell Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing. 2020-08-07 10.1016/j.cell.2020.07.017 view
Sawada Mol. Psychiatry Developmental excitation-inhibition imbalance underlying psychoses revealed by single-cell analyses of discordant twins-derived cerebral organoids. 2020-08-07 10.1038/s41380-020-0844-z view
Wang Genome Biol. Integrative analyses of single-cell transcriptome and regulome using MAESTRO. 2020-08-07 10.1186/s13059-020-02116-x view
Couturier Nat Commun Author Correction: Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy. 2020-08-07 10.1038/s41467-020-17979-8 view
Monsanto Nat Commun Enhancing myocardial repair with CardioClusters. 2020-08-07 10.1038/s41467-020-17742-z view
Tillie Curr. Opin. Lipidol. Fibroblasts in atherosclerosis: heterogeneous and plastic participants. 2020-08-06 10.1097/MOL.0000000000000700 view
Villanueva Cell Finding a Needle in a Haystack: Identification of a Beige Fat Progenitor. 2020-08-06 10.1016/j.cell.2020.07.014 view
Theocharidis Diabetes Integrated Skin Transcriptomics and Serum Multiplex Assays Reveal Novel Mechanisms of Wound Healing in Diabetic Foot Ulcers. 2020-08-06 10.2337/db20-0188 view
Li J. Am. Soc. Nephrol. Integration of GWAS Summary Statistics and Gene Expression Reveals Target Cell Types Underlying Kidney Function Traits. 2020-08-06 10.1681/ASN.2020010051 view
Silvin Cell Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19. 2020-08-05 10.1016/j.cell.2020.08.002 view
Schulte-Schrepping Cell Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. 2020-08-05 10.1016/j.cell.2020.08.001 17 view
Lau Dev. Cell Single-Cell RNA Sequencing of the Cynomolgus Macaque Testis Reveals Conserved Transcriptional Profiles during Mammalian Spermatogenesis. 2020-08-05 10.1016/j.devcel.2020.07.018 view
Kortekaas Cancer Immunol Res CD39 identifies the CD4+ tumor-specific T cell population in human cancer. 2020-08-05 10.1158/2326-6066.CIR-20-0270 view
Choi BMC Bioinformatics scTyper: a comprehensive pipeline for the cell typing analysis of single-cell RNA-seq data. 2020-08-04 10.1186/s12859-020-03700-5 view
Brubaker Sci Signal An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease. 2020-08-04 10.1126/scisignal.aay3258 view
Peng Gene Clinical and genomic landscape of hepatocellular carcinoma subtypes with various proportions of nonleukocyte stromal cells. 2020-08-04 10.1016/j.gene.2020.145028 view
Wiseman EBioMedicine Chronic myelomonocytic leukaemia stem cell transcriptomes anticipate disease morphology and outcome. 2020-08-04 10.1016/j.ebiom.2020.102904 1 view
Fortelny Genome Biol. Knowledge-primed neural networks enable biologically interpretable deep learning on single-cell sequencing data. 2020-08-03 10.1186/s13059-020-02100-5 view
Geistlinger Cancer Res. Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinoma. 2020-08-03 10.1158/0008-5472.CAN-20-0521 view
Jiang Proc. Natl. Acad. Sci. U.S.A. Multidimensional study of the heterogeneity of leukemia cells in t(8;21) acute myelogenous leukemia identifies the subtype with poor outcome. 2020-08-03 10.1073/pnas.2003900117 view
Bergen Nat. Biotechnol. Generalizing RNA velocity to transient cell states through dynamical modeling. 2020-08-03 10.1038/s41587-020-0591-3 view
Nehar-Belaid Nat. Immunol. Mapping systemic lupus erythematosus heterogeneity at the single-cell level. 2020-08-03 10.1038/s41590-020-0743-0 view
Corridoni Nat. Med. Single-cell atlas of colonic CD8+ T cells in ulcerative colitis. 2020-08-03 10.1038/s41591-020-1003-4 view
Tristan bioRxiv Robotic High-Throughput Biomanufacturing and Functional Differentiation of Human Pluripotent Stem Cells. 2020-08-03 10.1101/2020.08.03.235242 view
Lai Cell Regen Mapping a mammalian adult adrenal gland hierarchy across species by microwell-seq. 2020-08-03 10.1186/s13619-020-00042-8 view
He Mol Genet Genomic Med Single-cell RNA sequencing analysis of human kidney reveals the presence of ACE2 receptor: A potential pathway of COVID-19 infection. 2020-08-03 10.1002/mgg3.1442 3 view
Magnusson Elife Activation of a neural stem cell transcriptional program in parenchymal astrocytes. 2020-08-03 10.7554/eLife.59733 view
Ge Dev. Dyn. Two new genetically modified mouse alleles labeling distinct phases of retinal ganglion cell development by fluorescent proteins. 2020-08-02 10.1002/dvdy.233 view
Wazny Open Biol Vascular underpinning of COVID-19. 2020-08-01 10.1098/rsob.200208 view
Centonze Nature Heterotypic cell-cell communication regulates glandular stem cell multipotency. 2020-08-01 10.1038/s41586-020-2632-y view
Kreimann Front Immunol Ischemia Reperfusion Injury Triggers CXCL13 Release and B-Cell Recruitment After Allogenic Kidney Transplantation. 2020-08-01 10.3389/fimmu.2020.01204 view
Fastrès Front Immunol Characterization of the Bronchoalveolar Lavage Fluid by Single Cell Gene Expression Analysis in Healthy Dogs: A Promising Technique. 2020-08-01 10.3389/fimmu.2020.01707 view
Wu Front Immunol Redefining Tumor-Associated Macrophage Subpopulations and Functions in the Tumor Microenvironment. 2020-08-01 10.3389/fimmu.2020.01731 view
Chen Front Genet Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts. 2020-08-01 10.3389/fgene.2020.00867 view
Hao Adv. Exp. Med. Biol. Neural Regulation of Feeding Behavior. 2020-08-01 10.1007/978-981-15-7086-5_3 view
Wlodarczyk J Oncol Gaps and Doubts in Search to Recognize Glioblastoma Cellular Origin and Tumor Initiating Cells. 2020-08-01 10.1155/2020/6783627 view
Hu Comput Struct Biotechnol J Integration of single-cell multi-omics for gene regulatory network inference. 2020-08-01 10.1016/j.csbj.2020.06.033 view
Zhou J Immunol Res Single-Cell Transcriptome Analysis Profile of Meniscal Tissue Macrophages in Human Osteoarthritis. 2020-08-01 10.1155/2020/8127281 view
Fischer Mol. Syst. Biol. Predicting antigen specificity of single T cells based on TCR CDR3 regions. 2020-08-01 10.15252/msb.20199416 view
Xu Cell Death Discov Digestive symptoms of COVID-19 and expression of ACE2 in digestive tract organs. 2020-08-01 10.1038/s41420-020-00307-w view
Wouters Nat. Cell Biol. Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma. 2020-08-01 10.1038/s41556-020-0547-3 1 view
Zolfaghari Emameh Biol Proced Online Expansion of Single Cell Transcriptomics Data of SARS-CoV Infection in Human Bronchial Epithelial Cells to COVID-19. 2020-08-01 10.1186/s12575-020-00127-3 view
Huang Theranostics Stem cell programs in cancer initiation, progression, and therapy resistance. 2020-08-01 10.7150/thno.41648 view
Liu Theranostics Single-cell analysis reveals immune landscape in kidneys of patients with chronic transplant rejection. 2020-08-01 10.7150/thno.48201 view
Zhang Ann Transl Med Identification of hub genes in diabetic kidney disease via multiple-microarray analysis. 2020-08-01 10.21037/atm-20-5171 view
Zou Ann Transl Med Percutaneous liver biopsy: another option of hepatic sample collection approach in single-cell sequencing studies? 2020-08-01 10.21037/atm.2020.04.23 view
Na Theranostics Reciprocal change in Glucose metabolism of Cancer and Immune Cells mediated by different Glucose Transporters predicts Immunotherapy response. 2020-08-01 10.7150/thno.48954 view
Chittezhath J. Endocrinol. TLR4 signals through islet macrophages to alter cytokine secretion during diabetes. 2020-08-01 10.1530/JOE-20-0131 view
Lee Immune Netw Effects of Cryopreservation and Thawing on Single-Cell Transcriptomes of Human T Cells. 2020-08-01 10.4110/in.2020.20.e34 view
Macedo Gigascience The intersectional genetics landscape for humans. 2020-08-01 10.1093/gigascience/giaa083 view
Noé J Immunol Res The Application of Single-Cell RNA Sequencing in Vaccinology. 2020-08-01 10.1155/2020/8624963 view
Arai J. Cereb. Blood Flow Metab. Can oligodendrocyte precursor cells be a therapeutic target for mitigating cognitive decline in cerebrovascular disease? 2020-08-01 10.1177/0271678X20929432 view
Fu F1000Res clustifyr: an R package for automated single-cell RNA sequencing cluster classification. 2020-08-01 10.12688/f1000research.22969.1 view
Sheng Sci Adv Social reprogramming in ants induces longevity-associated glia remodeling. 2020-08-01 10.1126/sciadv.aba9869 view
Zhou Int. J. Biol. Sci. Encoding Method of Single-cell Spatial Transcriptomics Sequencing. 2020-08-01 10.7150/ijbs.43887 view
de Vries Front Oncol Unraveling the Complexity of the Cancer Microenvironment With Multidimensional Genomic and Cytometric Technologies. 2020-08-01 10.3389/fonc.2020.01254 view
Regan NPJ Breast Cancer Integrating single-cell RNA-sequencing and functional assays to decipher mammary cell states and lineage hierarchies. 2020-08-01 10.1038/s41523-020-00175-8 view
Chu Hepatology The Power of Single Cell Analysis for the Study of Liver Pathobiology. 2020-08-01 10.1002/hep.31485 view
Arsenio Methods Mol. Biol. Single-Cell Transcriptomics of Immune Cells: Cell Isolation and cDNA Library Generation for scRNA-Seq. 2020-08-01 10.1007/978-1-0716-0802-9_1 view
Kleino Methods Mol. Biol. The Conjugation of Antibodies for the Simultaneous Detection of Surface Proteins and Transcriptome Analysis at a Single-Cell Level. 2020-08-01 10.1007/978-1-0716-0802-9_3 view
Rassek Cancers (Basel) Single-Cell Heterogeneity of Cutaneous T-Cell Lymphomas Revealed Using RNA-Seq Technologies. 2020-07-31 10.3390/cancers12082129 view
Abbasi Cell Stem Cell Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. 2020-07-31 10.1016/j.stem.2020.07.008 view
Ge J. Am. Soc. Nephrol. LIM-Nebulette Reinforces Podocyte Structural Integrity by Linking Actin and Vimentin Filaments. 2020-07-31 10.1681/ASN.2019121261 view
Brann Sci Adv Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia. 2020-07-31 10.1126/sciadv.abc5801 view
Smits Cell Tissue Res. Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids. 2020-07-31 10.1007/s00441-020-03249-y view
Gruber Immunity Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. 2020-07-30 10.1016/j.immuni.2020.07.006 view
McLellan Circulation High-Resolution Transcriptomic Profiling of the Heart During Chronic Stress Reveals Cellular Drivers of Cardiac Fibrosis and Hypertrophy. 2020-07-30 10.1161/CIRCULATIONAHA.119.045115 view
Zamboni Cell Stem Cell A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury. 2020-07-30 10.1016/j.stem.2020.07.006 view
Melton Bioinformatics Discovering a sparse set of pairwise discriminating features in high dimensional data. 2020-07-30 10.1093/bioinformatics/btaa690 view
Xin Genome Biol. GMM-Demux: sample demultiplexing, multiplet detection, experiment planning, and novel cell-type verification in single cell sequencing. 2020-07-30 10.1186/s13059-020-02084-2 view
Crosby Clin. Cancer Res. Stimulation of Oncogene-Specific Tumor-Infiltrating T Cells through Combined Vaccine and αPD-1 Enable Sustained Antitumor Responses against Established HER2 Breast Cancer. 2020-07-30 10.1158/1078-0432.CCR-20-0389 view
Yao Nat Commun Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis. 2020-07-30 10.1038/s41467-020-17630-6 view
Van Hove Diabetologia Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy. 2020-07-30 10.1007/s00125-020-05218-0 view
Gao bioRxiv SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors. 2020-07-30 10.1101/2020.07.29.227462 view
Avrahami Mol Metab Single cell transcriptomics of human islet ontogeny defines the molecular basis of β cell dedifferentiation in T2D. 2020-07-30 10.1016/j.molmet.2020.101057 view
Zhang J Cachexia Sarcopenia Muscle Age-related decline of interferon-gamma responses in macrophage impairs satellite cell proliferation and regeneration. 2020-07-29 10.1002/jcsm.12584 view
Wattrus Zebrafish A Transgenic System for Rapid Magnetic Enrichment of Rare Embryonic Cells. 2020-07-29 10.1089/zeb.2020.1904 view
Choi Cell Stem Cell Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration. 2020-07-29 10.1016/j.stem.2020.06.020 view
Dong Bioinformatics netAE: Semi-supervised dimensionality reduction of single-cell RNA sequencing to facilitate cell labeling. 2020-07-29 10.1093/bioinformatics/btaa669 view
Zuo Respir. Res. Cell-specific expression of lung disease risk-related genes in the human small airway epithelium. 2020-07-29 10.1186/s12931-020-01442-9 view
Lemme-Dumit mSphere mSphere of Influence: Organoids and Single-Cell Sequencing, a Powerful Combination To Uncover Epithelial and Immune Cell Interactions in the Human Gut Environment. 2020-07-29 10.1128/mSphere.00722-20 view
Lee Proc. Natl. Acad. Sci. U.S.A. Single-cell RNA-seq analysis revealed long-lasting adverse effects of tamoxifen on neurogenesis in prenatal and adult brains. 2020-07-29 10.1073/pnas.1918883117 view
Muciño-Olmos Sci Rep Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq. 2020-07-29 10.1038/s41598-020-69026-7 view
Aragona Nature Mechanisms of stretch-mediated skin expansion at single-cell resolution. 2020-07-29 10.1038/s41586-020-2555-7 view
Grosswendt Nature Epigenetic regulator function through mouse gastrulation. 2020-07-29 10.1038/s41586-020-2552-x view
Selmi Clin Rev Allergy Immunol Autoimmunity in 2019. 2020-07-29 10.1007/s12016-020-08808-3 view
Iwanaga Am. J. Respir. Crit. Care Med. Spelunking in Sputum: Single Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis. 2020-07-28 10.1164/rccm.202006-2456ED view
León-Rivera mBio Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities. 2020-07-28 10.1128/mBio.01037-20 view
Sheng Cell Rep Cycling Stem Cells Are Radioresistant and Regenerate the Intestine. 2020-07-28 10.1016/j.celrep.2020.107952 view
Zhao FASEB J. Single-cell RNA sequencing reveals the landscape of early female germ cell development. 2020-07-27 10.1096/fj.202001034RR view
Zheng PLoS Comput. Biol. scPADGRN: A preconditioned ADMM approach for reconstructing dynamic gene regulatory network using single-cell RNA sequencing data. 2020-07-27 10.1371/journal.pcbi.1007471 view
Choi Genome Biol. Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics. 2020-07-27 10.1186/s13059-020-02103-2 view
He J Hematol Oncol Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies. 2020-07-27 10.1186/s13045-020-00924-z view
Fei Cell Death Dis High-dimensional single-cell analysis delineates radiofrequency ablation induced immune microenvironmental remodeling in pancreatic cancer. 2020-07-27 10.1038/s41419-020-02787-1 view
Xie Nat. Immunol. Single-cell transcriptome profiling reveals neutrophil heterogeneity in homeostasis and infection. 2020-07-27 10.1038/s41590-020-0736-z view
Zarei Lab. Invest. Early pathogenesis of cystic fibrosis gallbladder disease in a porcine model. 2020-07-27 10.1038/s41374-020-0474-8 view
Li J Genet Genomics Landscape of transcript isoforms in single T cells infiltrating in non-small-cell lung cancer. 2020-07-27 10.1016/j.jgg.2020.06.006 view
Ravasz Cereb. Cortex Cell Surface Protein mRNAs Show Differential Transcription in Pyramidal and Fast-Spiking Cells as Revealed by Single-Cell Sequencing. 2020-07-27 10.1093/cercor/bhaa195 view
Salahudeen bioRxiv Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures. 2020-07-27 10.1101/2020.07.27.212076 view
Iqbal Cytometry A Status and Potential of Single-cell Transcriptomics for Understanding Plant Development and Functional Biology. 2020-07-26 10.1002/cyto.a.24196 view
Boroughs Mol. Ther. A Distinct Transcriptional Program in Human CAR T Cells Bearing the 4-1BB Signaling Domain Revealed by scRNA-Seq. 2020-07-25 10.1016/j.ymthe.2020.07.023 view
Atamian Semin. Cell Dev. Biol. Taming human brain organoids one cell at a time. 2020-07-24 10.1016/j.semcdb.2020.05.022 view
Yao medRxiv Cell type-specific immune dysregulation in severely ill COVID-19 patients. 2020-07-24 10.1101/2020.07.23.20161182 view
Manresa Gastroenterology Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype. 2020-07-23 10.1053/j.gastro.2020.07.035 view
Dubois J. Invest. Dermatol. Defining the Skin Cellular Community Using Single-Cell Genomics to Advance Precision Medicine. 2020-07-23 10.1016/j.jid.2020.05.104 view
Pedroza Arterioscler. Thromb. Vasc. Biol. Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm. 2020-07-23 10.1161/ATVBAHA.120.314670 view
Guo Cancer Med TOX correlates with prognosis, immune infiltration, and T cells exhaustion in lung adenocarcinoma. 2020-07-23 10.1002/cam4.3324 view
Peyvandipour Sci Rep Identification of cell types from single cell data using stable clustering. 2020-07-23 10.1038/s41598-020-66848-3 view
Giadone Stem Cell Reports Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease. 2020-07-23 10.1016/j.stemcr.2020.07.003 view
An bioRxiv Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2. 2020-07-23 10.1101/2020.07.23.212357 view
Fung J. Neurogenet. Cell-type-specific promoters for C. elegans glia. 2020-07-22 10.1080/01677063.2020.1781851 view
Song Genome Biol. Single-cell RNA-seq analysis reveals ploidy-dependent and cell-specific transcriptome changes in Arabidopsis female gametophytes. 2020-07-22 10.1186/s13059-020-02094-0 view
Townes Genome Biol. Author Correction: Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model. 2020-07-22 10.1186/s13059-020-02109-w view
Xing Genome Res. Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility. 2020-07-22 10.1101/gr.257840.119 view
Gupta Cells Biological and Medical Importance of Cellular Heterogeneity Deciphered by Single-Cell RNA Sequencing. 2020-07-22 10.3390/cells9081751 view
He Ocul Surf Tissue engineered corneal epithelium derived from clinical-grade human embryonic stem cells. 2020-07-22 10.1016/j.jtos.2020.07.009 view
Cai Circ. Res. Impact of Local Allo-Immunity and Recipient Cells in Transplant Arteriosclerosis. 2020-07-21 10.1161/CIRCRESAHA.119.316470 view
Carraro Am. J. Respir. Crit. Care Med. Single Cell Reconstruction of Human Basal Cell Diversity in Normal and IPF Lung. 2020-07-21 10.1164/rccm.201904-0792OC 2 view
Verma BMC Bioinformatics A robust nonlinear low-dimensional manifold for single cell RNA-seq data. 2020-07-21 10.1186/s12859-020-03625-z view
Michel Cell Rep Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction. 2020-07-21 10.1016/j.celrep.2020.107912 view
Zagozewski Nat Commun An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate. 2020-07-20 10.1038/s41467-020-17357-4 view
Chen Cell Res. Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma. 2020-07-20 10.1038/s41422-020-0374-x view
Wang Cell Res. Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level. 2020-07-20 10.1038/s41422-020-0378-6 view
Abbas Nat. Immunol. The activation trajectory of plasmacytoid dendritic cells in vivo during a viral infection. 2020-07-20 10.1038/s41590-020-0731-4 view
Skinnider Nat. Biotechnol. Cell type prioritization in single-cell data. 2020-07-20 10.1038/s41587-020-0605-1 view
Legouis Nat Metab Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality. 2020-07-20 10.1038/s42255-020-0238-1 view
Garman Curr Opin Pulm Med Recent advances in sarcoidosis genomics: epigenetics, gene expression, and gene by environment (G × E) interaction studies. 2020-07-20 10.1097/MCP.0000000000000719 view
Pasciuto Cell Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition. 2020-07-20 10.1016/j.cell.2020.06.026 1 view
Abplanalp Nucleic Acid Ther Efficiency and Target Derepression of Anti-miR-92a: Results of a First in Human Study. 2020-07-20 10.1089/nat.2020.0871 view
Cochrane J. Pathol. Single cell transcriptomes of normal endometrial derived organoids uncover novel cell type markers and cryptic differentiation of primary tumours. 2020-07-19 10.1002/path.5511 view
Zhang Aging (Albany NY) PDIA3 correlates with clinical malignant features and immune signature in human gliomas. 2020-07-19 10.18632/aging.103601 view
Lavker Exp. Eye Res. Corneal epithelial biology: Lessons stemming from old to new. 2020-07-19 10.1016/j.exer.2020.108094 view
Zhu Immunity Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients. 2020-07-19 10.1016/j.immuni.2020.07.009 view
Moudgil Cell Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells. 2020-07-18 10.1016/j.cell.2020.06.037 view
Zernecke Circ. Res. Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas. 2020-07-17 10.1161/CIRCRESAHA.120.316903 view
Alencar Circulation The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis. 2020-07-17 10.1161/CIRCULATIONAHA.120.046672 view
Chi Science Cancer cells deploy lipocalin-2 to collect limiting iron in leptomeningeal metastasis. 2020-07-17 10.1126/science.aaz2193 2 view
Zhao Cardiovasc. Res. Single cell RNA sequencing reveals the cellular heterogeneity of aneurysmal infrarenal abdominal aorta. 2020-07-17 10.1093/cvr/cvaa214 view
Mahata Nat Commun Tumors induce de novo steroid biosynthesis in T cells to evade immunity. 2020-07-17 10.1038/s41467-020-17339-6 1 view
Bao Cancer Immunol. Immunother. Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels tumour heterogeneity plus M2-like tumour-associated macrophage infiltration and aggressiveness in TNBC. 2020-07-17 10.1007/s00262-020-02669-7 view
Han Protein Cell Bi-FoRe: an efficient bidirectional knockin strategy to generate pairwise conditional alleles with fluorescent indicators. 2020-07-17 10.1007/s13238-020-00747-1 view
Orange N. Engl. J. Med. RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares. 2020-07-16 10.1056/NEJMoa2004114 view
Huber J. Clin. Invest. Immobilization after injury alters extracellular matrix and stem cell fate. 2020-07-16 10.1172/JCI136142 view
Aguiar Eur. Respir. J. Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue. 2020-07-16 10.1183/13993003.01123-2020 view
Strunz Nat Commun Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis. 2020-07-16 10.1038/s41467-020-17358-3 view
Deng Cancers (Basel) Cylindromatosis Lysine 63 Deubiquitinase (CYLD) Regulates NF-kB Signaling Pathway and Modulates Fibroblast and Endothelial Cells Recruitment in Nasopharyngeal Carcinoma. 2020-07-16 10.3390/cancers12071924 view
Eyler Genome Biol. Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. 2020-07-15 10.1186/s13059-020-02085-1 view
Malone J. Am. Soc. Nephrol. Harnessing Expressed Single Nucleotide Variation and Single Cell RNA Sequencing To Define Immune Cell Chimerism in the Rejecting Kidney Transplant. 2020-07-15 10.1681/ASN.2020030326 view
Tiklová Nat Commun Author Correction: Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. 2020-07-15 10.1038/s41467-020-17421-z view
Rodriguez-Fraticelli Nature Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis. 2020-07-15 10.1038/s41586-020-2503-6 view
Schaum Nature Ageing hallmarks exhibit organ-specific temporal signatures. 2020-07-15 10.1038/s41586-020-2499-y view
Hao J. Assist. Reprod. Genet. Culture of human ovarian tissue in xeno-free conditions using laminin components of the human ovarian extracellular matrix. 2020-07-15 10.1007/s10815-020-01886-4 view
Haftbaradaran Esfahani Biophys Rev Cell shape: effects on gene expression and signaling. 2020-07-15 10.1007/s12551-020-00722-4 view
Pfefferlé J. Clin. Invest. Hemolysis transforms liver macrophages into anti-inflammatory erythrophagocytes. 2020-07-14 10.1172/JCI137282 view
Loeuillard J. Clin. Invest. Targeting tumor-associated macrophages and granulocytic-myeloid-derived suppressor cells augments pd-1 blockade in cholangiocarcinoma. 2020-07-14 10.1172/JCI137110 view
Arroyo Hornero Commun Biol CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells. 2020-07-14 10.1038/s42003-020-1097-8 view
Chen Genes (Basel) Integrating Deep Supervised, Self-Supervised and Unsupervised Learning for Single-Cell RNA-seq Clustering and Annotation. 2020-07-14 10.3390/genes11070792 view
Smith Curr. Opin. Neurobiol. New light on cortical neuropeptides and synaptic network plasticity. 2020-07-14 10.1016/j.conb.2020.04.002 view
Li Curr. Opin. Genet. Dev. Lessons from single cell sequencing in CNS cell specification and function. 2020-07-14 10.1016/j.gde.2020.05.043 view
Yang Clin Transl Med Analysis of single-cell RNAseq identifies transitional states of T cells associated with hepatocellular carcinoma. 2020-07-13 10.1002/ctm2.133 view
Tan Proc. Natl. Acad. Sci. U.S.A. Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro. 2020-07-13 10.1073/pnas.2000362117 view
Kobayashi Nat. Cell Biol. Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis. 2020-07-13 10.1038/s41556-020-0542-8 view
Sacher Cancer Cell Cytotoxic CD4+ T Cells in Bladder Cancer-A New License to Kill. 2020-07-13 10.1016/j.ccell.2020.06.013 view
Gojo Cancer Cell Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma. 2020-07-13 10.1016/j.ccell.2020.06.004 view
Green Oncogene Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer. 2020-07-13 10.1038/s41388-020-1379-0 view
Liu J. Cell. Physiol. Weighted gene co-expression network analysis can sort cancer-associated fibroblast-specific markers promoting bladder cancer progression. 2020-07-13 10.1002/jcp.29939 view
Ding Cancer Commun (Lond) Single-cell RNA sequencing in breast cancer: Understanding tumor heterogeneity and paving roads to individualized therapy. 2020-07-12 10.1002/cac2.12078 view
Zhong Clin Transl Oncol Immune cell infiltration features and related marker genes in lung cancer based on single-cell RNA-seq. 2020-07-12 10.1007/s12094-020-02435-2 view
Cuarental J Clin Med Tacrolimus Prevents TWEAK-Induced PLA2R Expression in Cultured Human Podocytes. 2020-07-10 10.3390/jcm9072178 view
He Genome Biol. DISC: a highly scalable and accurate inference of gene expression and structure for single-cell transcriptomes using semi-supervised deep learning. 2020-07-10 10.1186/s13059-020-02083-3 view
Vanarsa Ann. Rheum. Dis. Quantitative planar array screen of 1000 proteins uncovers novel urinary protein biomarkers of lupus nephritis. 2020-07-10 10.1136/annrheumdis-2019-216312 view
Lee Sci Immunol Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19. 2020-07-10 10.1126/sciimmunol.abd1554 view
Wineberg J. Am. Soc. Nephrol. Single-Cell RNA Sequencing Reveals mRNA Splice Isoform Switching during Kidney Development. 2020-07-10 10.1681/ASN.2019080770 view
Chung J. Am. Soc. Nephrol. Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury. 2020-07-10 10.1681/ASN.2020020220 view
Cao Nat Commun Searching large-scale scRNA-seq databases via unbiased cell embedding with Cell BLAST. 2020-07-10 10.1038/s41467-020-17281-7 view
Vieira JCI Insight Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes. 2020-07-09 10.1172/jci.insight.137230 view
Fang Anal. Chem. A single-cell multimodal analytical approach by integrating Raman optical tweezers and RNA sequencing. 2020-07-09 10.1021/acs.analchem.0c00912 view
Chen Environ. Sci. Technol. Single-cell sequencing reveals heterogeneity effects of bisphenol A on zebrafish embryonic development. 2020-07-09 10.1021/acs.est.0c02428 view
Tsoi JCI Insight IL-18-containing five-gene signature distinguishes histologically identical dermatomyositis and lupus erythematosus skin lesions. 2020-07-09 10.1172/jci.insight.139558 view
Liu Genome Biol. Genome-wide studies reveal the essential and opposite roles of ARID1A in controlling human cardiogenesis and neurogenesis from pluripotent stem cells. 2020-07-09 10.1186/s13059-020-02082-4 view
Klimovich Proc. Natl. Acad. Sci. U.S.A. Prototypical pacemaker neurons interact with the resident microbiota. 2020-07-09 10.1073/pnas.1920469117 view
Ellison Pancreas Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel. 2020-07-09 10.1097/MPA.0000000000001612 view
Edil BMC Med Genomic and single cell sequencing facilitate the dissection of heterogeneity of pancreatic tumors. 2020-07-08 10.1186/s12916-020-01637-3 view
Hou Zygote Maternal ageing causes changes in DNA methylation and gene expression profiles in mouse oocytes. 2020-07-08 10.1017/S0967199420000143 view
Abplanalp JAMA Cardiol Association of Clonal Hematopoiesis of Indeterminate Potential With Inflammatory Gene Expression in Patients With Severe Degenerative Aortic Valve Stenosis or Chronic Postischemic Heart Failure. 2020-07-08 10.1001/jamacardio.2020.2468 view
Can BMC Genomics Comparative analysis of single-cell transcriptomics in human and Zebrafish oocytes. 2020-07-08 10.1186/s12864-020-06860-z view
Patrick Genome Biol. Sierra: discovery of differential transcript usage from polyA-captured single-cell RNA-seq data. 2020-07-08 10.1186/s13059-020-02071-7 view
Starostik Genome Res. Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism. 2020-07-08 10.1101/gr.262774.120 view
Couturier Nat Commun Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy. 2020-07-08 10.1038/s41467-020-17186-5 view
Cho J Cachexia Sarcopenia Muscle Single-cell deconstruction of post-sepsis skeletal muscle and adipose tissue microenvironments. 2020-07-08 10.1002/jcsm.12596 view
Pérez Mol. Psychiatry Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids. 2020-07-07 10.1038/s41380-020-0807-4 view
Fonseca Costa Brief Funct Genomics Single-cell transcriptomics allows novel insights into aging and circadian processes. 2020-07-07 10.1093/bfgp/elaa014 view
Frost Nucleic Acids Res. Variance-adjusted Mahalanobis (VAM): a fast and accurate method for cell-specific gene set scoring. 2020-07-07 10.1093/nar/gkaa582 view
Beisang Sci Rep Single-cell RNA sequencing reveals that lung mesenchymal progenitor cells in IPF exhibit pathological features early in their differentiation trajectory. 2020-07-07 10.1038/s41598-020-66630-5 view
Song Int. J. Cancer Cellular Heterogeneity Landscape in Laryngeal Squamous Cell Carcinoma. 2020-07-07 10.1002/ijc.33192 view
Holmes Cell Rep Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis. 2020-07-07 10.1016/j.celrep.2020.107871 view
Jackson Cell Rep Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma. 2020-07-07 10.1016/j.celrep.2020.107872 view
Qu Cell Rep Baseline Frequency of Inflammatory Cxcl9-Expressing Tumor-Associated Macrophages Predicts Response to Avelumab Treatment. 2020-07-07 10.1016/j.celrep.2020.107873 view
Renand J. Hepatol. Integrative molecular profiling of autoreactive CD4 T cells in autoimmune hepatitis. 2020-07-07 10.1016/j.jhep.2020.05.053 view
Terabayashi Cell. Signal. Pathway identification through transcriptome analysis. 2020-07-07 10.1016/j.cellsig.2020.109701 view
Li Cell Regen (Lond) Comparison of Scanpy-based algorithms to remove the batch effect from single-cell RNA-seq data. 2020-07-06 10.1186/s13619-020-00041-9 view
DeSisto Dev. Cell Single-Cell Transcriptomic Analyses of the Developing Meninges Reveal Meningeal Fibroblast Diversity and Function. 2020-07-06 10.1016/j.devcel.2020.06.009 view
De Micheli Skelet Muscle A reference single-cell transcriptomic atlas of human skeletal muscle tissue reveals bifurcated muscle stem cell populations. 2020-07-06 10.1186/s13395-020-00236-3 view
Deutsch Int J Mol Sci The Impact of Single-Cell Genomics on Adipose Tissue Research. 2020-07-05 10.3390/ijms21134773 view
Li Gene Single cell sequencing revealed the underlying pathogenesis of the development of osteoarthritis. 2020-07-05 10.1016/j.gene.2020.144939 view
Matsuda Food Chem. Toxicol. The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix. 2020-07-05 10.1016/j.fct.2020.111556 view
Zhang Clin Transl Med How far is single-cell sequencing from clinical application? 2020-07-05 10.1002/ctm2.117 view
Alexander Glia Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma. 2020-07-04 10.1002/glia.23866 view
Ji Genome Biol. Single-cell ATAC-seq signal extraction and enhancement with SCATE. 2020-07-03 10.1186/s13059-020-02075-3 view
Townes Genome Biol. Quantile normalization of single-cell RNA-seq read counts without unique molecular identifiers. 2020-07-03 10.1186/s13059-020-02078-0 view
Alvarez Sci Rep Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM. 2020-07-03 10.1038/s41598-020-67513-5 view
Su Bioinformatics Simulation, Power Evaluation, and Sample Size Recommendation for Single Cell RNA-seq. 2020-07-02 10.1093/bioinformatics/btaa607 view
Fidanza Blood Single cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs. 2020-07-02 10.1182/blood.2020006229 view
Southard-Smith BMC Genomics Dual indexed library design enables compatibility of in-Drop single-cell RNA-sequencing with exAMP chemistry sequencing platforms. 2020-07-02 10.1186/s12864-020-06843-0 view
Chou Sci Rep Synovial cell cross-talk with cartilage plays a major role in the pathogenesis of osteoarthritis. 2020-07-02 10.1038/s41598-020-67730-y view
Patir Sci Rep The transcriptional signature associated with human motile cilia. 2020-07-02 10.1038/s41598-020-66453-4 view
Tikhonova Cell Stem Cell Cell-by-Cell Deconstruction of Stem Cell Niches. 2020-07-02 10.1016/j.stem.2020.06.013 view
Strong Bone Small molecule inhibition of non-canonical (TAK1-mediated) BMP signaling results in reduced chondrogenic ossification and heterotopic ossification in a rat model of blast-associated combat-related lower limb trauma. 2020-07-02 10.1016/j.bone.2020.115517 view
Zhou ChemRxiv A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19. 2020-07-02 10.26434/chemrxiv.12579137.v1 view
Zhang Cell Biol. Toxicol. Single-cell sequencing reveals novel mechanisms of Aflatoxin B1-induced hepatotoxicity in S phase-arrested L02 cells. 2020-07-01 10.1007/s10565-020-09547-z view
Meng Bioinformatics GPress: a framework for querying General Feature Format (GFF) files and expression files in a compressed form. 2020-07-01 10.1093/bioinformatics/btaa604 view
Ge Theranostics Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. 2020-07-01 10.7150/thno.44306 view
Sagar Annu Rev Biomed Data Sci Deciphering Cell Fate Decision by Integrated Single-Cell Sequencing Analysis. 2020-07-01 10.1146/annurev-biodatasci-111419-091750 view
Rath Sci Adv Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8αβ-engineered human CD4+ T cells. 2020-07-01 10.1126/sciadv.aaz7809 view
Niebler BMC Bioinformatics RainDrop: Rapid activation matrix computation for droplet-based single-cell RNA-seq reads. 2020-07-01 10.1186/s12859-020-03593-4 view
Canu Genome Biol. Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation. 2020-07-01 10.1186/s13059-020-02058-4 view
Luo Cancer Discov Utility of Human-Derived Models for Glioblastoma. 2020-07-01 10.1158/2159-8290.CD-20-0493 view
Zhang Cell. Mol. Immunol. The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications. 2020-07-01 10.1038/s41423-020-0488-6 view
Song Nat Commun Flexible experimental designs for valid single-cell RNA-sequencing experiments allowing batch effects correction. 2020-07-01 10.1038/s41467-020-16905-2 view
Schetters J Immunother Cancer Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy. 2020-07-01 10.1136/jitc-2020-000588 view
Liang Bioinformatics BEM: Mining Coregulation Patterns in Transcriptomics via Boolean Matrix Factorization. 2020-07-01 10.1093/bioinformatics/btz977 view
Eura Front Neurosci Brainstem Organoids From Human Pluripotent Stem Cells. 2020-07-01 10.3389/fnins.2020.00538 view
Bowman Proteomics Advanced Cell Mapping Visualizations for Single Cell Functional Proteomics Enabling Patient Stratification. 2020-07-01 10.1002/pmic.201900270 view
Zheng Adv Sci (Weinh) Trajectory and Functional Analysis of PD-1high CD4+CD8+ T Cells in Hepatocellular Carcinoma by Single-Cell Cytometry and Transcriptome Sequencing. 2020-07-01 10.1002/advs.202000224 view
He Nature The changing mouse embryo transcriptome at whole tissue and single-cell resolution. 2020-07-01 10.1038/s41586-020-2536-x view
Seweryn Comput Struct Biotechnol J Application of information theoretical approaches to assess diversity and similarity in single-cell transcriptomics. 2020-07-01 10.1016/j.csbj.2020.05.005 view
Habermann Sci Adv Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis. 2020-07-01 10.1126/sciadv.aba1972 view
Adams Sci Adv Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis. 2020-07-01 10.1126/sciadv.aba1983 view
Menden Sci Adv Deep learning-based cell composition analysis from tissue expression profiles. 2020-07-01 10.1126/sciadv.aba2619 2 view
Garrido-Martin J Immunother Cancer M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer. 2020-07-01 10.1136/jitc-2020-000778 view
Ásgrímsdóttir Front Cell Dev Biol Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells. 2020-07-01 10.3389/fcell.2020.00463 view
Stanley Fertil. Steril. Coronavirus disease-19 and fertility: viral host entry protein expression in male and female reproductive tissues. 2020-07-01 10.1016/j.fertnstert.2020.05.001 view
Cardoso Front Cell Dev Biol Toward Generating Subtype-Specific Mesencephalic Dopaminergic Neurons in vitro. 2020-07-01 10.3389/fcell.2020.00443 view
Sagar EMBO J. Deciphering the regulatory landscape of fetal and adult γδ T-cell development at single-cell resolution. 2020-07-01 10.15252/embj.2019104159 view
Bao J Immunother Cancer ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19. 2020-07-01 10.1136/jitc-2020-001020 view
Capdevila Methods Mol. Biol. Single-Cell Transcriptional Profiling of the Intestinal Epithelium. 2020-07-01 10.1007/978-1-0716-0747-3_8 view
Norkin Methods Mol. Biol. Single-Cell Studies of Intestinal Stem Cell Heterogeneity During Homeostasis and Regeneration. 2020-07-01 10.1007/978-1-0716-0747-3_9 view
Tawil Thromb. Res. Genetic and epigenetic regulation of cancer coagulome - lessons from heterogeneity of cancer cell populations. 2020-07-01 10.1016/S0049-3848(20)30405-9 view
Sadeqi Azer Bioinformatics PhISCS-BnB: a fast branch and bound algorithm for the perfect tumor phylogeny reconstruction problem. 2020-07-01 10.1093/bioinformatics/btaa464 view
Hodzic Bioinformatics Identification of conserved evolutionary trajectories in tumors. 2020-07-01 10.1093/bioinformatics/btaa453 view
DeMeo Bioinformatics Hopper: a mathematically optimal algorithm for sketching biological data. 2020-07-01 10.1093/bioinformatics/btaa408 view
Lian Bioinformatics Artificial-cell-type aware cell-type classification in CITE-seq. 2020-07-01 10.1093/bioinformatics/btaa467 view
Myers Bioinformatics Identifying tumor clones in sparse single-cell mutation data. 2020-07-01 10.1093/bioinformatics/btaa449 view
Tao Bioinformatics Robust and accurate deconvolution of tumor populations uncovers evolutionary mechanisms of breast cancer metastasis. 2020-07-01 10.1093/bioinformatics/btaa396 view
Srivastava Bioinformatics A Bayesian framework for inter-cellular information sharing improves dscRNA-seq quantification. 2020-07-01 10.1093/bioinformatics/btaa450 view
Wainer-Katsir Bioinformatics BIRD: identifying cell doublets via biallelic expression from single cells. 2020-07-01 10.1093/bioinformatics/btaa474 view
Todorov Bioinformatics TinGa: fast and flexible trajectory inference with Growing Neural Gas. 2020-07-01 10.1093/bioinformatics/btaa463 view
Esaulova Neurol Neuroimmunol Neuroinflamm Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation. 2020-07-01 10.1212/NXI.0000000000000732 view
Gandhi Int J Mol Sci Contribution of Immune Cells to Glucocorticoid Receptor Expression in Breast Cancer. 2020-06-30 10.3390/ijms21134635 view
Vitrinel ACS Omega Simple Method to Quantify Protein Abundances from 1000 Cells. 2020-06-30 10.1021/acsomega.0c01191 view
Alexander Eur Respir Rev Breathing fresh air into respiratory research with single-cell RNA sequencing. 2020-06-30 10.1183/16000617.0060-2020 view
Zhang Crit. Rev. Oncol. Hematol. Revealing the molecular mechanism of central nervous system leukemia with single-cell technology. 2020-06-30 10.1016/j.critrevonc.2020.103046 view
Liegeois Elife An atlas for hemocytes in an insect. 2020-06-30 10.7554/eLife.59113 view
Schupp Am. J. Respir. Crit. Care Med. Single Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis. 2020-06-30 10.1164/rccm.202004-0991OC view
Alda-Catalinas Cell Syst A Single-Cell Transcriptomics CRISPR-Activation Screen Identifies Epigenetic Regulators of the Zygotic Genome Activation Program. 2020-06-29 10.1016/j.cels.2020.06.004 view
Buen Abad Najar Elife Coverage-dependent bias creates the appearance of binary splicing in single cells. 2020-06-29 10.7554/eLife.54603 view
Calls Neuro-oncology Cisplatin-induced peripheral neuropathy is associated to neuronal senescence-like response. 2020-06-29 10.1093/neuonc/noaa151 view
Onsbring BMC Genomics An efficient single-cell transcriptomics workflow for microbial eukaryotes benchmarked on Giardia intestinalis cells. 2020-06-29 10.1186/s12864-020-06858-7 view
Yousif BMC Bioinformatics NASQAR: a web-based platform for high-throughput sequencing data analysis and visualization. 2020-06-29 10.1186/s12859-020-03577-4 view
Kaspi BMC Genomics mitch: multi-contrast pathway enrichment for multi-omics and single-cell profiling data. 2020-06-29 10.1186/s12864-020-06856-9 view
Gupta Proc. Natl. Acad. Sci. U.S.A. Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism. 2020-06-29 10.1073/pnas.2003603117 view
Alivernini Nat. Med. Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis. 2020-06-29 10.1038/s41591-020-0939-8 view
Laidlaw Nat. Immunol. The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development. 2020-06-29 10.1038/s41590-020-0713-6 view
Shen J. Cell. Mol. Med. The ACE2 expression in Sertoli cells and germ cells may cause male reproductive disorder after SARS-CoV-2 infection. 2020-06-28 10.1111/jcmm.15541 view
Bigaeva Hum. Mol. Genet. Understanding human gut diseases at single-cell resolution. 2020-06-26 10.1093/hmg/ddaa130 view
Xu Nucleic Acids Res. scIGANs: single-cell RNA-seq imputation using generative adversarial networks. 2020-06-26 10.1093/nar/gkaa506 view
Cheng Cardiovasc. Res. Single-cell RNA sequencing reveals cell type- and artery-specific vascular remodeling in male spontaneously hypertensive rats. 2020-06-26 10.1093/cvr/cvaa164 view
Chua Nat. Biotechnol. COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis. 2020-06-26 10.1038/s41587-020-0602-4 view
Yang Brief. Bioinformatics SMNN: batch effect correction for single-cell RNA-seq data via supervised mutual nearest neighbor detection. 2020-06-26 10.1093/bib/bbaa097 view
Zhang Cancer Immunol. Immunother. Dynamics of peripheral T cell clones during PD-1 blockade in non-small cell lung cancer. 2020-06-26 10.1007/s00262-020-02642-4 view
Oguri Cell CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling. 2020-06-26 10.1016/j.cell.2020.06.021 view
Zheng World J Stem Cells Recent advances of single-cell RNA sequencing technology in mesenchymal stem cell research. 2020-06-26 10.4252/wjsc.v12.i6.438 view
Cowman Clin. Cancer Res. Macrophage HIF-1α is an independent prognostic indicator in kidney cancer. 2020-06-25 10.1158/1078-0432.CCR-19-3890 view
Velazquez-Villarreal Commun Biol Single-cell sequencing of genomic DNA resolves sub-clonal heterogeneity in a melanoma cell line. 2020-06-25 10.1038/s42003-020-1044-8 view
Liu Mol Plant Global Dynamic Molecular Profiles of Stomatal Lineage Cell Development by Single-Cell RNA Sequencing. 2020-06-24 10.1016/j.molp.2020.06.010 1 view
Shin Cell. Immunol. IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8+ T cells in high dimensional analysis. 2020-06-24 10.1016/j.cellimm.2020.104155 view
Hertzano Laryngoscope Cell Type-Specific Expression Analysis of the Inner Ear: A Technical Report. 2020-06-24 10.1002/lary.28765 1 view
Chen Genome Biol. Single-cell transcriptome and antigen-immunoglobin analysis reveals the diversity of B cells in non-small cell lung cancer. 2020-06-24 10.1186/s13059-020-02064-6 1 view
Trzupek Genome Med Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis. 2020-06-24 10.1186/s13073-020-00756-z 1 view
Bian Development A single cell transcriptional atlas of early synovial joint development. 2020-06-24 10.1242/dev.185777 view
Sekine Sci Rep Robust detection of undifferentiated iPSC among differentiated cells. 2020-06-24 10.1038/s41598-020-66845-6 view
Wu Blood Adv Sequencing of RNA in single cells reveals a distinct transcriptome signature of hematopoiesis in GATA2 deficiency. 2020-06-23 10.1182/bloodadvances.2019001352 view
Chen J. Infect. Molecular identification of Cryptococcus gattii from cerebrospinal fluid using single-cell sequencing: a case study. 2020-06-23 10.1016/j.jinf.2020.06.040 view
Sun Mol Omics LRSK: a low-rank self-representation K-means method for clustering single-cell RNA-sequencing data. 2020-06-23 10.1039/d0mo00034e view
Patra Biol Open Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations. 2020-06-23 10.1242/bio.052993 view
Cheng Cell Rep NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma. 2020-06-23 10.1016/j.celrep.2020.107782 view
Mizrak Cell Rep Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator. 2020-06-23 10.1016/j.celrep.2020.107805 view
Goad bioRxiv Female reproductive tract has low concentration of SARS-CoV2 receptors. 2020-06-22 10.1101/2020.06.20.163097 view
Okaty Elife A single-cell transcriptomic and anatomic atlas of mouse dorsal raphe Pet1 neurons. 2020-06-22 10.7554/eLife.55523 view
Wen J. Bone Miner. Res. Runx2 regulates mouse tooth root development via activation of WNT inhibitor Notum. 2020-06-22 10.1002/jbmr.4120 view
Spakowicz Genome Biol. Approaches for integrating heterogeneous RNA-seq data reveal cross-talk between microbes and genes in asthmatic patients. 2020-06-22 10.1186/s13059-020-02033-z view
Griffiths Proc. Natl. Acad. Sci. U.S.A. Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy. 2020-06-22 10.1073/pnas.1918937117 1 view
Liu Nat Commun An entropy-based metric for assessing the purity of single cell populations. 2020-06-22 10.1038/s41467-020-16904-3 view
Izar Nat. Med. A single-cell landscape of high-grade serous ovarian cancer. 2020-06-22 10.1038/s41591-020-0926-0 view
Biasini iScience The Contribution of lincRNAs at the Interface between Cell Cycle Regulation and Cell State Maintenance. 2020-06-20 10.1016/j.isci.2020.101291 view
Schüler Mech. Ageing Dev. Stem Cell Aging: The Upcoming Era of Proteins and Metabolites. 2020-06-20 10.1016/j.mad.2020.111288 view
Bain Sci Immunol Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages. 2020-06-19 10.1126/sciimmunol.abc4466 view
Qian Cell Res. A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling. 2020-06-19 10.1038/s41422-020-0355-0 view
Van de Sande Nat Protoc A scalable SCENIC workflow for single-cell gene regulatory network analysis. 2020-06-19 10.1038/s41596-020-0336-2 view
Bernstein Cell Syst Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning. 2020-06-19 10.1016/j.cels.2020.05.010 view
Cosacak STAR Protoc Protocol for Dissection and Dissociation of Zebrafish Telencephalon for Single-Cell Sequencing. 2020-06-19 10.1016/j.xpro.2020.100042 view
Ji Cell Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma. 2020-06-19 10.1016/j.cell.2020.05.039 7 view
Kempski Gastroenterology IL22BP Mediates the Anti-Tumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans. 2020-06-18 10.1053/j.gastro.2020.06.033 view
Hao Am. J. Respir. Crit. Care Med. GWAS Functional Variant rs2076295 Regulates Desmoplakin (DSP) Expression in Airway Epithelial Cells. 2020-06-18 10.1164/rccm.201910-1958OC view
Gray J. Biol. Chem. Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells. 2020-06-18 10.1074/jbc.RA120.014368 view
Pang Genome Res. Coexpression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders. 2020-06-18 10.1101/gr.254987.119 view
Jiang JCI Insight Single cell rna sequencing identifies an early monocyte gene signature in acute respiratory distress syndrome. 2020-06-18 10.1172/jci.insight.135678 view
Deng Curr Atheroscler Rep New Classification of Macrophages in Plaques: a Revolution. 2020-06-18 10.1007/s11883-020-00850-y view
Aubin-Frankowski Bioinformatics Gene regulation inference from single-cell RNA-seq data with linear differential equations and velocity inference. 2020-06-17 10.1093/bioinformatics/btaa576 view
Hong J. Immunol. IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice. 2020-06-17 10.4049/jimmunol.2000280 view
Yan Sci Rep Cell Atlas of The Human Fovea and Peripheral Retina. 2020-06-17 10.1038/s41598-020-66092-9 view
Bica Sci Rep Unsupervised generative and graph representation learning for modelling cell differentiation. 2020-06-17 10.1038/s41598-020-66166-8 1 view
Hu Nature Lineage dynamics of the endosymbiotic cell type in the soft coral Xenia. 2020-06-17 10.1038/s41586-020-2385-7 view
Rodgers Exp. Cell Res. Identification of immune and non-immune cells in regenerating axolotl limbs by single-cell sequencing. 2020-06-17 10.1016/j.yexcr.2020.112149 view
Li Cell Rep Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites. 2020-06-16 10.1016/j.celrep.2020.107765 view
Le Immunity Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineage Specification Trajectories and a Commitment Spectrum in T Cell Development. 2020-06-16 10.1016/j.immuni.2020.05.010 2 view
Jin Emerg Microbes Infect Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site. 2020-06-16 10.1080/22221751.2020.1781551 1 view
Zafar Nat Commun Single-cell lineage tracing by integrating CRISPR-Cas9 mutations with transcriptomic data. 2020-06-16 10.1038/s41467-020-16821-5 view
Hwang Bone Activin A does not drive post-traumatic heterotopic ossification. 2020-06-15 10.1016/j.bone.2020.115473 view
Al Tanoury Development Differentiation of the human PAX7-positive myogenic precursors/satellite cell lineage in vitro. 2020-06-15 10.1242/dev.187344 view
Ren Cell Res. Reconstruction of cell spatial organization from single-cell RNA sequencing data based on ligand-receptor mediated self-assembly. 2020-06-15 10.1038/s41422-020-0353-2 view
Roider Nat. Cell Biol. Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels. 2020-06-15 10.1038/s41556-020-0532-x view
Lorenzo Nucleic Acids Res. Combining single-cell RNA-sequencing with a molecular atlas unveils new markers for Caenorhabditis elegans neuron classes. 2020-06-15 10.1093/nar/gkaa486 view
Summers FASEB J. Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling. 2020-06-13 10.1096/fj.202000629R view
Yi Oncogene Integrative multi-omics analysis of a colon cancer cell line with heterogeneous Wnt activity revealed RUNX2 as an epigenetic regulator of EMT. 2020-06-13 10.1038/s41388-020-1351-z view
Delley Lab Chip Microfluidic particle zipper enables controlled loading of droplets with distinct particle types. 2020-06-12 10.1039/d0lc00339e view
Aguirre-Gamboa BMC Bioinformatics Deconvolution of bulk blood eQTL effects into immune cell subpopulations. 2020-06-12 10.1186/s12859-020-03576-5 view
Srinivasan RNA A Hybrid Deep Clustering Approach for Robust Cell Type Profiling Using Single-cell RNA-seq Data. 2020-06-12 10.1261/rna.074427.119 2 view
Li Cancer Immunol Res The Mincle/Syk/NF-κB Signalling Circuit is Essential for Maintaining the Protumoral Activities of Tumor-associated Macrophages. 2020-06-12 10.1158/2326-6066.CIR-19-0782 view
Zhang Gut Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing. 2020-06-12 10.1136/gutjnl-2019-320368 view
Kim J. Dermatol. Sci. Application of single-cell RNA sequencing on human skin: Technical evolution and challenges. 2020-06-12 10.1016/j.jdermsci.2020.06.002 view
Pollard Biochem. J. Thermogenic adipocytes: lineage, function and therapeutic potential. 2020-06-12 10.1042/BCJ20200298 view
Qi BMC Bioinformatics A flexible network-based imputing-and-fusing approach towards the identification of cell types from single-cell RNA-seq data. 2020-06-11 10.1186/s12859-020-03547-w view
Pellegrini Science Human CNS barrier-forming organoids with cerebrospinal fluid production. 2020-06-11 10.1126/science.aaz5626 view
Takayama Sci Rep Selective Induction of Human Autonomic Neurons Enables Precise Control of Cardiomyocyte Beating. 2020-06-11 10.1038/s41598-020-66303-3 view
Lee Genes (Basel) Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract. 2020-06-11 10.3390/genes11060645 view
Saviano J. Hepatol. Single-cell genomics and spatial transcriptomics: discovery of novel cell states and cellular interactions in liver physiology and disease biology. 2020-06-10 10.1016/j.jhep.2020.06.004 view
Jackson-Weaver Cell Rep PRMT1-p53 Pathway Controls Epicardial EMT and Invasion. 2020-06-09 10.1016/j.celrep.2020.107739 view
Voigt Microvasc. Res. Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype. 2020-06-09 10.1016/j.mvr.2020.104031 view
Kuwahara Elife Delineating the early transcriptional specification of the mammalian trachea and esophagus. 2020-06-09 10.7554/eLife.55526 view
Barwinska J Vis Exp Application of Laser Microdissection to Uncover Regional Transcriptomics in Human Kidney Tissue. 2020-06-09 10.3791/61371 view
Hagey Nat Commun CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment. 2020-06-09 10.1038/s41467-020-16597-8 view
Jung Int. J. Cancer Neuronal signatures in cancer. 2020-06-08 10.1002/ijc.33138 view
Guo J. Cell. Physiol. Single-cell RNA analysis on ACE2 expression provides insights into SARS-CoV-2 potential entry into the bloodstream and heart injury. 2020-06-08 10.1002/jcp.29802 view
Song Genome Biol. Direct-seq: programmed gRNA scaffold for streamlined scRNA-seq in CRISPR screen. 2020-06-08 10.1186/s13059-020-02044-w view
Ni Genome Biol. CB2 improves power of cell detection in droplet-based single-cell RNA sequencing data. 2020-06-08 10.1186/s13059-020-02054-8 view
Tan Proc. Natl. Acad. Sci. U.S.A. Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma. 2020-06-08 10.1073/pnas.2005353117 view
Schnepp Mol. Cancer Res. Single Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells. 2020-06-08 10.1158/1541-7786.MCR-20-0051 view
Wilk Nat. Med. A single-cell atlas of the peripheral immune response in patients with severe COVID-19. 2020-06-08 10.1038/s41591-020-0944-y view
Hsu Toxicol. Sci. Single cell RNA-seq analysis reveals that prenatal arsenic exposure results in long-term, adverse effects on immune gene expression in response to Influenza A infection. 2020-06-08 10.1093/toxsci/kfaa080 view
Zhao Methods Mol. Biol. Interactions of Hematopoietic Stem Cells with Bone Marrow Niche. 2020-06-06 10.1007/7651_2020_298 view
Hu PLoS Comput. Biol. Detecting differential alternative splicing events in scRNA-seq with or without Unique Molecular Identifiers. 2020-06-05 10.1371/journal.pcbi.1007925 view
Hjorton Arthritis Res. Ther. The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells. 2020-06-05 10.1186/s13075-020-02186-z view
LaMarche Cell Metab. Distinct iNKT Cell Populations Use IFNγ or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis. 2020-06-05 10.1016/j.cmet.2020.05.017 2 view
Zhang J. Hepatol. Single cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinoma. 2020-06-04 10.1016/j.jhep.2020.05.039 view
Teves Mol. Cells Mapping Cellular Coordinates through Advances in Spatial Transcriptomics Technology. 2020-06-04 10.14348/molcells.2020.0020 view
Joseph Prostate Urethral luminal epithelia are castration-insensitive cells of the proximal prostate. 2020-06-04 10.1002/pros.24020 view
Dimitrov-Markov Mol. Cancer Ther. Discovery of new targets to control metastasis in pancreatic cancer by single cell transcriptomics analysis of circulating tumor cells. 2020-06-04 10.1158/1535-7163.MCT-19-1166 view
Ye Biochem. Biophys. Res. Commun. Single-cell transcriptional profiling identifies a cluster of potential metastasis-associated UBE2C+ cells in immature ovarian teratoma. 2020-06-03 10.1016/j.bbrc.2020.05.144 view
Sanborn Sci Rep Analysis of cell-associated DENV RNA by oligo(dT) primed 5' capture scRNAseq. 2020-06-03 10.1038/s41598-020-65939-5 view
Lee Nature Hair-bearing human skin generated entirely from pluripotent stem cells. 2020-06-03 10.1038/s41586-020-2352-3 view
Wu Antiviral Res. A novel recombinant cccDNA-based mouse model with long term maintenance of rcccDNA and antigenemia. 2020-06-02 10.1016/j.antiviral.2020.104826 view
Collin Ocul Surf Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface. 2020-06-02 10.1016/j.jtos.2020.05.013 view
Shami Dev. Cell Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian Spermatogenesis. 2020-06-02 10.1016/j.devcel.2020.05.010 view
Engel JCI Insight Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD. 2020-06-02 10.1172/jci.insight.137990 view
Hsu JCI Insight Endogenous CCN family member WISP-1 inhibits trauma-induced heterotopic ossification. 2020-06-02 10.1172/jci.insight.135432 view
Denisenko Genome Biol. Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows. 2020-06-02 10.1186/s13059-020-02048-6 view
Chen J. Biol. Chem. Early cleavage of preimplantation embryos is regulated by tRNAGln-TTG-derived small RNAs present in mature spermatozoa. 2020-06-02 10.1074/jbc.RA120.013003 view
Xiong CNS Neurosci Ther Effect of intra- and inter-tumoral heterogeneity on molecular characteristics of primary IDH-wild type glioblastoma revealed by single-cell analysis. 2020-06-02 10.1111/cns.13396 view
Wesely Cell Rep Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells. 2020-06-02 10.1016/j.celrep.2020.107688 view
Seow J Indian Inst Sci Single-Cell RNA Sequencing for Precision Oncology: Current State-of-Art. 2020-06-02 10.1007/s41745-020-00178-1 view
Zhao Front Genet MFCNV: A New Method to Detect Copy Number Variations From Next-Generation Sequencing Data. 2020-06-01 10.3389/fgene.2020.00434 view
Kanton Methods Cell Biol. Single-cell genomic analysis of human cerebral organoids. 2020-06-01 10.1016/bs.mcb.2020.03.013 view
Lin Heliyon Establishment and transcriptomic analyses of a cattle rumen epithelial primary cells (REPC) culture by bulk and single-cell RNA sequencing to elucidate interactions of butyrate and rumen development. 2020-06-01 10.1016/j.heliyon.2020.e04112 view
Wang Front Bioeng Biotechnol Analysis of Gene Signatures of Tumor Microenvironment Yields Insight Into Mechanisms of Resistance to Immunotherapy. 2020-06-01 10.3389/fbioe.2020.00348 view
Zhou Front Cell Dev Biol Single-Cell RNA-Seq Analysis Uncovers Distinct Functional Human NKT Cell Sub-Populations in Peripheral Blood. 2020-06-01 10.3389/fcell.2020.00384 view
Zakharov J. Exp. Med. Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes. 2020-06-01 10.1084/jem.20192362 view
Hellings J. Allergy Clin. Immunol. Epithelial barriers in allergy and asthma. 2020-06-01 10.1016/j.jaci.2020.04.010 view
Cano-Gamez Front Genet From GWAS to Function: Using Functional Genomics to Identify the Mechanisms Underlying Complex Diseases. 2020-06-01 10.3389/fgene.2020.00424 view
Cao Front Genet SCSA: A Cell Type Annotation Tool for Single-Cell RNA-seq Data. 2020-06-01 10.3389/fgene.2020.00490 view
Andor NAR Genom Bioinform Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution. 2020-06-01 10.1093/nargab/lqaa016 view
Lin Mol. Syst. Biol. scClassify: sample size estimation and multiscale classification of cells using single and multiple reference. 2020-06-01 10.15252/msb.20199389 1 view
Wang Elife Tissue resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice. 2020-06-01 10.7554/eLife.57438 view
Mohanraj Nucleic Acids Res. CReSCENT: CanceR Single Cell ExpressioN Toolkit. 2020-06-01 10.1093/nar/gkaa437 view
Farouni Nat Commun Model-based analysis of sample index hopping reveals its widespread artifacts in multiplexed single-cell RNA-sequencing. 2020-06-01 10.1038/s41467-020-16522-z view
Schraivogel Nat. Methods Targeted Perturb-seq enables genome-scale genetic screens in single cells. 2020-06-01 10.1038/s41592-020-0837-5 view
Alonso F1000Res Prediction of cell position using single-cell transcriptomic data: an iterative procedure. 2020-06-01 10.12688/f1000research.20715.1 view
Wen Cell Discov Erratum: Author Correction: Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing. 2020-06-01 10.1038/s41421-020-00187-5 view
Ochiai Sci Adv Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells. 2020-06-01 10.1126/sciadv.aaz6699 view
Pyle Laryngoscope Investig Otolaryngol Applications of single-cell sequencing for the field of otolaryngology: A contemporary review. 2020-06-01 10.1002/lio2.388 view
Hagemann-Jensen Nat. Biotechnol. Single-cell RNA counting at allele and isoform resolution using Smart-seq3. 2020-06-01 10.1038/s41587-020-0497-0 view
Mereu Nat. Biotechnol. Benchmarking single-cell RNA-sequencing protocols for cell atlas projects. 2020-06-01 10.1038/s41587-020-0469-4 view
Londono J Immunol Regen Med Single Cell Sequencing Analysis of Lizard Phagocytic Cell Populations and Their Role in Tail Regeneration. 2020-06-01 10.1016/j.regen.2020.100029 view
Banerjee Front Cell Neurosci Increased Connexin36 Phosphorylation in AII Amacrine Cell Coupling of the Mouse Myopic Retina. 2020-06-01 10.3389/fncel.2020.00124 view
Chen Int. J. Biol. Sci. Ligand-receptor interaction atlas within and between tumor cells and T cells in lung adenocarcinoma. 2020-06-01 10.7150/ijbs.42080 view
Rollins Curr Protoc Immunol T Cell Receptor Engineered Lymphocytes for Cancer Therapy. 2020-06-01 10.1002/cpim.97 view
Choueiry J Immunother Cancer CD200 promotes immunosuppression in the pancreatic tumor microenvironment. 2020-06-01 10.1136/jitc-2019-000189 view
Lei Front Cell Dev Biol Cathepsin S and Protease-Activated Receptor-2 Drive Alloimmunity and Immune Regulation in Kidney Allograft Rejection. 2020-06-01 10.3389/fcell.2020.00398 view
Kosaric Mol. Ther. Macrophage Subpopulation Dynamics Shift following Intravenous Infusion of Mesenchymal Stromal Cells. 2020-05-30 10.1016/j.ymthe.2020.05.022 view
Messerschmidt Int. J. Cancer Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC. 2020-05-29 10.1002/ijc.33123 view
Foltz Nat Commun Evolution and structure of clinically relevant gene fusions in multiple myeloma. 2020-05-29 10.1038/s41467-020-16434-y view
Xu Development Unifying Developmental Programs for Embryonic and Post-Embryonic Neurogenesis in the Zebrafish Retina. 2020-05-28 10.1242/dev.185660 view
Zhang Cell Biol. Toxicol. Single-cell transcriptomics uncovers potential marker genes of ochratoxin A-sensitive renal cells in an acute toxicity rat model. 2020-05-28 10.1007/s10565-020-09531-7 view
An Int J Mol Sci CSI NGS Portal: An Online Platform for Automated NGS Data Analysis and Sharing. 2020-05-28 10.3390/ijms21113828 view
Gutmann Antioxid. Redox Signal. The Landscape of Coding and Non-coding RNAs in Platelets. 2020-05-28 10.1089/ars.2020.8139 view
Venkatakrishnan Elife Knowledge synthesis of 100 million biomedical documents augments the deep expression profiling of coronavirus receptors. 2020-05-28 10.7554/eLife.58040 view
De Smet J. Hepatol. Single cell RNA sequencing analysis did not predict hepatocyte infection by SARS-CoV-2. 2020-05-27 10.1016/j.jhep.2020.05.030 view
Heijink Allergy Epithelial cell dysfunction, a major driver of asthma development. 2020-05-27 10.1111/all.14421 view
Bridges Am. J. Physiol. Lung Cell Mol. Physiol. Glucocorticoid Regulates Mesenchymal Cell Differentiation Required for Perinatal Lung Morphogenesis and Function. 2020-05-27 10.1152/ajplung.00459.2019 view
Lee Genome Med Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient. 2020-05-27 10.1186/s13073-020-00741-6 view
Cain Dis Model Mech Quantitative single-cell interactomes in normal and virus-infected mouse lungs. 2020-05-27 10.1242/dmm.044404 1 view
Shao Nat Commun Genome and single-cell RNA-sequencing of the earthworm Eisenia andrei identifies cellular mechanisms underlying regeneration. 2020-05-27 10.1038/s41467-020-16454-8 view
Anand Elife SARS-CoV-2 strategically mimics proteolytic activation of human ENaC. 2020-05-26 10.7554/eLife.58603 view
Zhou Circulation Single-Cell Transcriptomics: New Insights in Heart Research. 2020-05-26 10.1161/CIRCULATIONAHA.120.046043 view
Borcherding JCI Insight A transcriptomic map of murine and human alopecia areata. 2020-05-26 10.1172/jci.insight.137424 view
Liu Sci Signal Myeloma cells shift osteoblastogenesis to adipogenesis by inhibiting the ubiquitin ligase MURF1 in mesenchymal stem cells. 2020-05-26 10.1126/scisignal.aay8203 view
Chen Proc. Natl. Acad. Sci. U.S.A. Forward genetic analysis using OCT screening identifies Sfxn3 mutations leading to progressive outer retinal degeneration in mice. 2020-05-26 10.1073/pnas.1921224117 view
Huang Proc. Natl. Acad. Sci. U.S.A. Putative regulators for the continuum of erythroid differentiation revealed by single-cell transcriptome of human BM and UCB cells. 2020-05-26 10.1073/pnas.1915085117 view
Karagiannis Nat Commun Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program. 2020-05-26 10.1038/s41467-020-16159-y view
Song Cell Res. The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget's disease. 2020-05-26 10.1038/s41422-020-0334-5 view
Rai IEEE/ACM Trans Comput Biol Bioinform SelfE: Gene Selection via Self-Expression for Single-Cell Data. 2020-05-25 10.1109/TCBB.2020.2997326 view
Winge Am J Med Genet C Semin Med Genet Integration and reanalysis of transcriptomics and methylomics data derived from blood and testis tissue of men with 47,XXY Klinefelter syndrome indicates the primary involvement of Sertoli cells in the testicular pathogenesis. 2020-05-25 10.1002/ajmg.c.31793 view
David Nucleic Acids Res. ASAP 2020 update: an open, scalable and interactive web-based portal for (single-cell) omics analyses. 2020-05-25 10.1093/nar/gkaa412 view
Mangale Glia Microglia influence host defense, disease, and repair following murine coronavirus infection of the central nervous system. 2020-05-25 10.1002/glia.23844 view
Wu Genome Biol. Accounting for cell type hierarchy in evaluating single cell RNA-seq clustering. 2020-05-25 10.1186/s13059-020-02027-x view
Blattman Nat Microbiol Prokaryotic single-cell RNA sequencing by in situ combinatorial indexing. 2020-05-25 10.1038/s41564-020-0729-6 view
Rifes Nat. Biotechnol. Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient. 2020-05-25 10.1038/s41587-020-0525-0 view
Gerard BMC Bioinformatics Data-based RNA-seq simulations by binomial thinning. 2020-05-24 10.1186/s12859-020-3450-9 view
Pfister Curr. Biol. Odorant Receptor Inhibition Is Fundamental to Odor Encoding. 2020-05-23 10.1016/j.cub.2020.04.086 view
Schuler bioRxiv Age-related expression of SARS-CoV-2 priming protease TMPRSS2 in the developing lung. 2020-05-23 10.1101/2020.05.22.111187 view
Arivazhagan Circ. Res. An Eclectic Cast of Cellular Actors Orchestrates Innate Immune Responses in the Mechanisms Driving Obesity and Metabolic Perturbation. 2020-05-22 10.1161/CIRCRESAHA.120.315900 view
Kim Circulation The Environment-Sensing Aryl-Hydrocarbon Receptor Inhibits the Chondrogenic Fate of Modulated Smooth Muscle Cells in Atherosclerotic Lesions. 2020-05-22 10.1161/CIRCULATIONAHA.120.045981 view
Song J. Med. Virol. Systematic Analysis of ACE2 and TMPRSS2 Expression in Salivary Glands Reveals Underlying Transmission Mechanism Caused by SARS-CoV-2. 2020-05-22 10.1002/jmv.26045 view
Corbin Sci Immunol IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation. 2020-05-22 10.1126/sciimmunol.aax6085 view
Sato Sci Rep Characterization of radioresistant epithelial stem cell heterogeneity in the damaged mouse intestine. 2020-05-22 10.1038/s41598-020-64987-1 view
Wang Nat Commun Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation. 2020-05-22 10.1038/s41467-020-16204-w view
Luo Trends Plant Sci. Single-Cell Genomics and Epigenomics: Technologies and Applications in Plants. 2020-05-22 10.1016/j.tplants.2020.04.016 view
Bai ACS Nano An Integrated Dielectrophoresis -Trapping and Nanowell Transfer Approach to Enable Double-Sub-Poisson Single-Cell RNA-Sequencing. 2020-05-21 10.1021/acsnano.0c02953 view
Zhang Bioinformatics scTPA: A web tool for single-cell transcriptome analysis of pathway activation signatures. 2020-05-21 10.1093/bioinformatics/btaa532 view
Patel Proc. Natl. Acad. Sci. U.S.A. Molecular taxonomy of human ocular outflow tissues defined by single-cell transcriptomics. 2020-05-21 10.1073/pnas.2001896117 view
Manialawy J. Biol. Chem. The magnesium transporter NIPAL1 is a pancreatic islet-expressed protein that conditionally impacts insulin secretion. 2020-05-21 10.1074/jbc.RA120.013277 view
Zhang J Vis Exp High Throughput Yeast Strain Phenotyping with Droplet-Based RNA Sequencing. 2020-05-21 10.3791/61014 view
Soliman Matrix Biol. Cardiac fibroblast diversity in health and disease. 2020-05-21 10.1016/j.matbio.2020.05.003 view
Sebastian Cancers (Basel) Single-Cell Transcriptomic Analysis of Tumor-Derived Fibroblasts and Normal Tissue-Resident Fibroblasts Reveals Fibroblast Heterogeneity in Breast Cancer. 2020-05-21 10.3390/cancers12051307 view
Adhyatmika Pharmaceutics Osteoprotegerin is More than a Possible Serum Marker in Liver Fibrosis: A Study into its Function in Human and Murine Liver. 2020-05-21 10.3390/pharmaceutics12050471 view
Yeo Cell Stem Cell A Multiplexed Barcodelet Single-Cell RNA-Seq Approach Elucidates Combinatorial Signaling Pathways that Drive ESC Differentiation. 2020-05-21 10.1016/j.stem.2020.04.020 view
Shao Protein Cell New avenues for systematically inferring cell-cell communication: through single-cell transcriptomics data. 2020-05-21 10.1007/s13238-020-00727-5 1 view
Bian Nature Deciphering human macrophage development at single-cell resolution. 2020-05-20 10.1038/s41586-020-2316-7 view
Mandric iScience BATMAN: Fast and Accurate Integration of Single-Cell RNA-Seq Datasets via Minimum-Weight Matching. 2020-05-20 10.1016/j.isci.2020.101185 view
Ni Immunity Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity. 2020-05-20 10.1016/j.immuni.2020.05.001 view
Hua Circulation Single-Cell RNA Sequencing to Dissect the Immunological Network of Autoimmune Myocarditis. 2020-05-20 10.1161/CIRCULATIONAHA.119.043545 view
Wang Bioengineered Dendritic cells in tumor microenvironment promoted the neuropathic pain via paracrine inflammatory and growth factors. 2020-05-20 10.1080/21655979.2020.1771068 view
Jeong Comput Biol Chem Effective single-cell clustering through ensemble feature selection and similarity measurements. 2020-05-19 10.1016/j.compbiolchem.2020.107283 view
Riccetti Matrix Biol. The Elephant in the Lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration. 2020-05-19 10.1016/j.matbio.2020.05.002 view
Xu Anal. Chem. A Highly Sensitive, Accurate and Automated Single-cell RNA Sequencing Platform with Digital Microfluidics. 2020-05-19 10.1021/acs.analchem.0c01613 view
Ayturk J. Bone Miner. Res. SINGLE CELL RNA SEQUENCING OF CALVARIAL AND LONG BONE ENDOCORTICAL CELLS. 2020-05-19 10.1002/jbmr.4052 view
Goldfarbmuren Nat Commun Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium. 2020-05-19 10.1038/s41467-020-16239-z 1 view
Macosko Nat. Biotechnol. Single-cell RNA sequencing at isoform resolution. 2020-05-19 10.1038/s41587-020-0553-9 view
Ovchinnikova Genome Res. Exploring dimension-reduced embeddings with Sleepwalk. 2020-05-19 10.1101/gr.251447.119 view
Xiong Curr Cardiol Rep Single-Cell Transcriptomic Analysis of Cardiac Progenitor Differentiation. 2020-05-19 10.1007/s11886-020-01285-2 view
Milner Immunity Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy. 2020-05-19 10.1016/j.immuni.2020.04.007 view
Davidson Cell Rep Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. 2020-05-19 10.1016/j.celrep.2020.107628 view
Ding Cell Rep Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis. 2020-05-19 10.1016/j.celrep.2020.107648 view
Huang Gene Single-cell profiling reveals sex diversity in human renal proximal tubules. 2020-05-18 10.1016/j.gene.2020.144790 view
Jariani Elife A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast. 2020-05-18 10.7554/eLife.55320 view
Schulz iScience Cellular and Molecular Changes of Brain Metastases-Associated Myeloid Cells during Disease Progression and Therapeutic Response. 2020-05-18 10.1016/j.isci.2020.101178 view
Inclan-Rico PLoS Pathog. Trichinella spiralis-induced mastocytosis and erythropoiesis are simultaneously supported by a bipotent mast cell/erythrocyte precursor cell. 2020-05-18 10.1371/journal.ppat.1008579 view
Ma Nucleic Acids Res. IRIS3: integrated cell-type-specific regulon inference server from single-cell RNA-Seq. 2020-05-18 10.1093/nar/gkaa394 view
Knudsen Gut Targeting dual signalling pathways in concert with immune checkpoints for the treatment of pancreatic cancer. 2020-05-18 10.1136/gutjnl-2020-321000 view
Miao Nat. Methods Putative cell type discovery from single-cell gene expression data. 2020-05-18 10.1038/s41592-020-0825-9 view
Wingo Nat. Neurosci. Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. 2020-05-18 10.1038/s41593-020-0635-5 view
Cao Cell Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells. 2020-05-18 10.1016/j.cell.2020.05.025 view
Collins Clin Transl Sci Interindividual Variability in Lymphocyte Stimulation and Transcriptomic Response Predicts Mycophenolic Acid Sensitivity in Healthy Volunteers. 2020-05-16 10.1111/cts.12795 view
Grønbech Bioinformatics scVAE: Variational auto-encoders for single-cell gene expression data. 2020-05-16 10.1093/bioinformatics/btaa293 view
Smith Dev. Cell Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract. 2020-05-16 10.1016/j.devcel.2020.05.012 view
Mitsialis Gastroenterology Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease. 2020-05-16 10.1053/j.gastro.2020.04.074 view
Li Int. J. Radiat. Oncol. Biol. Phys. Radiation-enhanced expression of CCL22 in nasopharyngeal carcinoma is associated with CCR4+ CD8 T cell recruitment. 2020-05-16 10.1016/j.ijrobp.2020.05.001 view
Ekiz BMC Bioinformatics CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments. 2020-05-15 10.1186/s12859-020-3538-2 view
Kurd Sci Immunol Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing. 2020-05-15 10.1126/sciimmunol.aaz6894 view
Tiklová Nat Commun Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease. 2020-05-15 10.1038/s41467-020-16225-5 view
Xu medRxiv Single-cell Transcriptome Analysis Indicates New Potential Regulation Mechanism of ACE2 and NPs signaling among heart failure patients infected with SARS-CoV-2. 2020-05-15 10.1101/2020.04.30.20081257 view
Johnston Gene Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia. 2020-05-15 10.1016/j.gene.2020.144758 view
Singh bioRxiv Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection. 2020-05-14 10.1101/2020.05.13.092536 view
Björn Genes (Basel) Single-Cell RNA Sequencing of Hematopoietic Stem and Progenitor Cells Treated with Gemcitabine and Carboplatin. 2020-05-14 10.3390/genes11050549 view
Yang Elife Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature. 2020-05-14 10.7554/eLife.51339 view
Ye Oncoimmunology Endogenous retroviral proteins provide an immunodominant but not requisite antigen in a murine immunotherapy tumor model. 2020-05-13 10.1080/2162402X.2020.1758602 view
Bingham Matrix Biol. Spatial-omics: Novel Approaches to Probe Cell Heterogeneity and Extracellular Matrix Biology. 2020-05-13 10.1016/j.matbio.2020.04.004 1 view
Baslan Elife Novel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing. 2020-05-13 10.7554/eLife.51480 view
Shi PLoS Biol. Vascularized human cortical organoids (vOrganoids) model cortical development in vivo. 2020-05-13 10.1371/journal.pbio.3000705 view
Park Exp. Mol. Med. MAPS-seq: magnetic bead-assisted parallel single-cell gene expression profiling. 2020-05-13 10.1038/s12276-020-0433-x view
Tattikota Elife A single-cell survey of Drosophila blood. 2020-05-12 10.7554/eLife.54818 1 view
Fava JCI Insight Integrated urine proteomics and renal single-cell genomics identify an interferon-γ response gradient in lupus nephritis. 2020-05-12 10.1172/jci.insight.138345 view
Vobořil Nat Commun Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation. 2020-05-12 10.1038/s41467-020-16081-3 view
Notter Mol. Psychiatry Neuronal activity increases translocator protein (TSPO) levels. 2020-05-12 10.1038/s41380-020-0745-1 view
Liao Nat. Med. Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19. 2020-05-12 10.1038/s41591-020-0901-9 view
Chen Bioinformatics An ultrasensitive T-cell receptor detection method for TCR-Seq and RNA-Seq data. 2020-05-12 10.1093/bioinformatics/btaa432 view
Vink Cell Rep Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells. 2020-05-12 10.1016/j.celrep.2020.107627 1 view
Katebi iScience Random Parametric Perturbations of Gene Regulatory Circuit Uncover State Transitions in Cell Cycle. 2020-05-11 10.1016/j.isci.2020.101150 view
Zhu Blood Developmental trajectory of pre-hematopoietic stem cell formation from endothelium. 2020-05-11 10.1182/blood.2020004801 view
Erbe Nucleic Acids Res. Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets. 2020-05-11 10.1093/nar/gkaa349 view
Hu BMC Bioinformatics SCeQTL: an R package for identifying eQTL from single-cell parallel sequencing data. 2020-05-11 10.1186/s12859-020-3534-6 view
Fiock eNeuro Increased Tau Expression Correlates with Neuronal Maturation in the Developing Human Cerebral Cortex. 2020-05-11 10.1523/ENEURO.0058-20.2020 view
Li Nat Commun Deep learning enables accurate clustering with batch effect removal in single-cell RNA-seq analysis. 2020-05-11 10.1038/s41467-020-15851-3 11 view
Adam Nat. Cell Biol. NFI transcription factors provide chromatin access to maintain stem cell identity while preventing unintended lineage fate choices. 2020-05-11 10.1038/s41556-020-0513-0 view
Chi Genes (Basel) Sparsity-Penalized Stacked Denoising Autoencoders for Imputing Single-Cell RNA-Seq Data. 2020-05-11 10.3390/genes11050532 view
Xi Cell Stem Cell A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. 2020-05-10 10.1016/j.stem.2020.04.017 view
Corridoni Inflamm. Bowel Dis. Inflammatory Bowel Disease Through the Lens of Single-cell RNA-seq Technologies. 2020-05-09 10.1093/ibd/izaa089 view
Kim Nat Commun Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma. 2020-05-08 10.1038/s41467-020-16164-1 view
Mazzu Mol Oncol Ribonucleotide reductase small subunit M2 is a master driver of aggressive prostate cancer. 2020-05-08 10.1002/1878-0261.12706 view
Bost Cell Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients. 2020-05-08 10.1016/j.cell.2020.05.006 view
Federico Nanomaterials (Basel) Transcriptomics in Toxicogenomics, Part II: Preprocessing and Differential Expression Analysis for High Quality Data. 2020-05-08 10.3390/nano10050903 view
Wang Nucleic Acids Res. BREM-SC: a bayesian random effects mixture model for joint clustering single cell multi-omics data. 2020-05-07 10.1093/nar/gkaa314 view
Chakraborty Cell Biol. Int. Single-cell sequencing of miRNAs: A modified technology. 2020-05-07 10.1002/cbin.11376 view
Dambroise J. Bone Miner. Res. Fgfr3 is a positive regulator of osteoblast expansion and differentiation during zebrafish skull vault development. 2020-05-07 10.1002/jbmr.4042 view
Uchigashima J. Biol. Chem. Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus. 2020-05-07 10.1074/jbc.AC120.012571 view
Kim Nat Commun Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease. 2020-05-07 10.1038/s41467-020-16115-w view
Shu Mol. Cell Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. 2020-05-07 10.1016/j.molcel.2020.04.027 view
Ravindra bioRxiv Single-cell longitudinal analysis of SARS-CoV-2 infection in human bronchial epithelial cells. 2020-05-07 10.1101/2020.05.06.081695 view
Nazaraliyev Curr. Opin. Hematol. In-vivo differentiation of adult hematopoietic stem cells from a single-cell point of view. 2020-05-07 10.1097/MOH.0000000000000587 view
Romanov Nature Molecular design of hypothalamus development. 2020-05-06 10.1038/s41586-020-2266-0 view
Bobyn BMC Med. Genet. Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer. 2020-05-06 10.1186/s12881-020-01033-x view
Marquina-Sanchez Genome Biol. Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets. 2020-05-06 10.1186/s13059-020-02006-2 view
Leir Cell Tissue Res. An organoid model to assay the role of CFTR in the human epididymis epithelium. 2020-05-06 10.1007/s00441-020-03208-7 view
Galow Cells Integrative Cluster Analysis of Whole Hearts Reveals Proliferative Cardiomyocytes in Adult Mice. 2020-05-06 10.3390/cells9051144 view
Heiser Cell Rep A Quantitative Framework for Evaluating Single-Cell Data Structure Preservation by Dimensionality Reduction Techniques. 2020-05-05 10.1016/j.celrep.2020.107576 view
Camps Cell Rep Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles. 2020-05-05 10.1016/j.celrep.2020.107597 view
Lee Cell Rep Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors. 2020-05-05 10.1016/j.celrep.2020.107605 view
Patterson medRxiv Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19. 2020-05-05 10.1101/2020.05.02.20084673 view
Xu J Mol Cell Biol Landscape of genomic imprinting and its functions in the mouse mammary gland. 2020-05-05 10.1093/jmcb/mjaa020 view
Cheng JCI Insight Identification of pathogenic TRAIL-expressing innate immune cells during HIV-1 infection in humanized mice by scRNA-seq. 2020-05-05 10.1172/jci.insight.135344 view
Choi Cells Single-Cell RNA Sequencing and Its Combination with Protein and DNA Analyses. 2020-05-04 10.3390/cells9051130 view
von Buchholtz Pain Assigning transcriptomic class in the trigeminal ganglion using multiplex in situ hybridization and machine learning. 2020-05-04 10.1097/j.pain.0000000000001911 view
Do iScience Sphetcher: Spherical Thresholding Improves Sketching of Single-Cell Transcriptomic Heterogeneity. 2020-05-04 10.1016/j.isci.2020.101126 view
Thiry Neuroscience Characterization of human iPSC-derived spinal motor neurons by single-cell RNA sequencing. 2020-05-04 10.1016/j.neuroscience.2020.04.041 view
Jardine Mol. Immunol. Reconstructing human DC, monocyte and macrophage development in utero using single cell technologies. 2020-05-04 10.1016/j.molimm.2020.04.023 view
Kagohara Br. J. Cancer Integrated single-cell and bulk gene expression and ATAC-seq reveals heterogeneity and early changes in pathways associated with resistance to cetuximab in HNSCC-sensitive cell lines. 2020-05-04 10.1038/s41416-020-0851-5 view
Forcato Brief. Bioinformatics Computational methods for the integrative analysis of single-cell data. 2020-05-04 10.1093/bib/bbaa042 view
Ran Bioinformatics scDoc: correcting drop-out events in single-cell RNA-seq data. 2020-05-04 10.1093/bioinformatics/btaa283 view
Lu Pediatr. Res. Rho/SMAD/mTOR triple inhibition enables long-term expansion of human neonatal tracheal aspirate-derived airway basal cell-like cells. 2020-05-04 10.1038/s41390-020-0925-3 1 view
Joe BMC Bioinformatics Prediction model construction of mouse stem cell pluripotency using CpG and non-CpG DNA methylation markers. 2020-05-04 10.1186/s12859-020-3448-3 view
Ligon Mucosal Immunol Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation. 2020-05-04 10.1038/s41385-020-0290-x view
Heaton Nat. Methods Souporcell: robust clustering of single-cell RNA-seq data by genotype without reference genotypes. 2020-05-04 10.1038/s41592-020-0820-1 view
Wang Cell Res. Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer. 2020-05-04 10.1038/s41422-020-0312-y view
Dong Nat. Cell Biol. Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis. 2020-05-04 10.1038/s41556-020-0512-1 view
Ge Cell. Mol. Life Sci. Dissecting the initiation of female meiosis in the mouse at single-cell resolution. 2020-05-04 10.1007/s00018-020-03533-8 view
Gandhi Dev. Cell Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects. 2020-05-04 10.1016/j.devcel.2020.04.005 view
Bockerstett Cell Mol Gastroenterol Hepatol Interleukin 27 Protects from Gastric Atrophy and Metaplasia during Chronic Autoimmune Gastritis. 2020-05-03 10.1016/j.jcmgh.2020.04.014 view
Choueiri J. Natl. Cancer Inst. Summary from the First Kidney Cancer Research Summit, September 12-13, 2019: A Focus on Translational Research. 2020-05-02 10.1093/jnci/djaa064 view
Wen Cell Discov Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing. 2020-05-01 10.1038/s41421-020-0168-9 116 view
Loving Front Physiol Lipid and Lipoprotein Metabolism in Microglia. 2020-05-01 10.3389/fphys.2020.00393 view
Yuan Front Bioeng Biotechnol Identifying Cell-Type Specific Genes and Expression Rules Based on Single-Cell Transcriptomic Atlas Data. 2020-05-01 10.3389/fbioe.2020.00350 view
Vrahatis Adv. Exp. Med. Biol. A Systems Biology Approach for the Identification of Active Molecular Pathways During the Progression of Alzheimer's Disease. 2020-05-01 10.1007/978-3-030-32622-7_28 view
Ye Comput Struct Biotechnol J Discovery of alternative polyadenylation dynamics from single cell types. 2020-05-01 10.1016/j.csbj.2020.04.009 view
Karthaus Science Regenerative potential of prostate luminal cells revealed by single-cell analysis. 2020-05-01 10.1126/science.aay0267 view
Pessoa Rodrigues Sci Adv Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. 2020-05-01 10.1126/sciadv.aaz4815 view
Ramirez Front Mol Biosci Toward Modeling Context-Specific EMT Regulatory Networks Using Temporal Single Cell RNA-Seq Data. 2020-05-01 10.3389/fmolb.2020.00054 1 view
Chen Curr. Top. Dev. Biol. Gene regulatory networks during the development of the Drosophila visual system. 2020-05-01 10.1016/bs.ctdb.2020.02.010 view
Zhang J. Immunol. UHRF1 Controls Thymocyte Fate Decisions through the Epigenetic Regulation of EGR1 Expression. 2020-05-01 10.4049/jimmunol.1901471 view
Cook Nat Commun Context specificity of the EMT transcriptional response. 2020-05-01 10.1038/s41467-020-16066-2 view
Cosacak Neural Regen Res Alzheimer's disease, neural stem cells and neurogenesis: cellular phase at single-cell level. 2020-05-01 10.4103/1673-5374.268896 view
Lu Life Sci Alliance Dynamic changes in the regulatory T-cell heterogeneity and function by murine IL-2 mutein. 2020-05-01 10.26508/lsa.201900520 view
Chen Front Genet Single-Cell Transcriptome Data Clustering via Multinomial Modeling and Adaptive Fuzzy K-Means Algorithm. 2020-05-01 10.3389/fgene.2020.00295 view
Podojil Oncoimmunology Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma. 2020-05-01 10.1080/2162402X.2020.1744897 view
Ku Sci Adv A single-cell view on alga-virus interactions reveals sequential transcriptional programs and infection states. 2020-05-01 10.1126/sciadv.aba4137 view
Thong Front Cell Dev Biol Hybrid Stem Cell States: Insights Into the Relationship Between Mammary Development and Breast Cancer Using Single-Cell Transcriptomics. 2020-05-01 10.3389/fcell.2020.00288 view
Kim Neuron Extraction of Distinct Neuronal Cell Types from within a Genetically Continuous Population. 2020-05-01 10.1016/j.neuron.2020.04.018 view
Qi Front Genet Single-Cell Transcriptomic Analysis Reveals Mitochondrial Dynamics in Oocytes of Patients With Polycystic Ovary Syndrome. 2020-05-01 10.3389/fgene.2020.00396 view
Zheng Front Genet An Adaptive Sparse Subspace Clustering for Cell Type Identification. 2020-05-01 10.3389/fgene.2020.00407 view
Liu Oncoimmunology Heterogeneity of exhausted T cells in the tumor microenvironment is linked to patient survival following resection in hepatocellular carcinoma. 2020-05-01 10.1080/2162402X.2020.1746573 view
Xiang Front Cardiovasc Med A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature. 2020-05-01 10.3389/fcvm.2020.00052 view
Bravo González-Blas Mol. Syst. Biol. Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics. 2020-05-01 10.15252/msb.20209438 view
Stevens J. Allergy Clin. Immunol. Activation of the 15-Lipoxygenase Pathway in Aspirin Exacerbated Respiratory Disease. 2020-05-01 10.1016/j.jaci.2020.04.031 1 view
Slyper Nat. Med. A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors. 2020-05-01 10.1038/s41591-020-0844-1 view
Yuen Nat. Med. High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade. 2020-05-01 10.1038/s41591-020-0860-1 view
Qadir Proc. Natl. Acad. Sci. U.S.A. Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche. 2020-04-30 10.1073/pnas.1918314117 view
Zhang Nat Commun Highly parallel and efficient single cell mRNA sequencing with paired picoliter chambers. 2020-04-30 10.1038/s41467-020-15765-0 view
Ramirez Nat Commun Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity. 2020-04-30 10.1038/s41467-020-16019-9 view
Liu Sci China Life Sci Single-cell transcriptome analysis of the novel coronavirus (SARS-CoV-2) associated gene ACE2 expression in normal and non-obstructive azoospermia (NOA) human male testes. 2020-04-30 10.1007/s11427-020-1705-0 view
Wilbrey-Clark Biochem. J. Cell Atlas technologies and insights into tissue architecture. 2020-04-30 10.1042/BCJ20190341 view
Ghinia Tegla Elife OTX2 represses sister cell fate choices in the developing retina to promote photoreceptor specification. 2020-04-29 10.7554/eLife.54279 view
Dragon J Biomol Tech Bioinformatics Core Survey Highlights the Challenges Facing Data Analysis Facilities. 2020-04-29 10.7171/jbt.20-3102-005 view
Jeong Bioinformatics PRIME: a probabilistic imputation method to reduce dropout effects in single cell RNA sequencing. 2020-04-29 10.1093/bioinformatics/btaa278 1 view
Toma eNeuro Peripheral Nerve Single Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth. 2020-04-29 10.1523/ENEURO.0066-20.2020 view
Cang Nat Commun Inferring spatial and signaling relationships between cells from single cell transcriptomic data. 2020-04-29 10.1038/s41467-020-15968-5 view
Liu Protein Cell Integrative analysis of in vivo recording with single-cell RNA-seq data reveals molecular properties of light-sensitive neurons in mouse V1. 2020-04-29 10.1007/s13238-020-00720-y view
Zhang IEEE J Biomed Health Inform SCCLRR: A Robust Computational Method for Accurate Clustering Single Cell RNA-seq Data. 2020-04-29 10.1109/JBHI.2020.2991172 view
Liu Neurobiol. Dis. Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis. 2020-04-29 10.1016/j.nbd.2020.104877 view
Hu Mol. Ther. Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes. 2020-04-29 10.1016/j.ymthe.2020.04.023 view
Furlan Blood Adv IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer. 2020-04-28 10.1182/bloodadvances.2019001248 view
Lu Dev. Cell Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development. 2020-04-28 10.1016/j.devcel.2020.04.009 view
Ajani Gut YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition. 2020-04-27 10.1136/gutjnl-2019-319748 view
Ziegler Cell SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues. 2020-04-27 10.1016/j.cell.2020.04.035 view
Sharma Circ. Res. Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression. 2020-04-27 10.1161/CIRCRESAHA.119.316461 4 view
Kakebeen Elife Chromatin accessibility dynamics and single cell RNA-Seq reveal new regulators of regeneration in neural progenitors. 2020-04-27 10.7554/eLife.52648 view
Peng Annu Rev Genomics Hum Genet Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development. 2020-04-27 10.1146/annurev-genom-120219-083220 view
Zhang PLoS Comput. Biol. Scedar: A scalable Python package for single-cell RNA-seq exploratory data analysis. 2020-04-27 10.1371/journal.pcbi.1007794 1 view
Jevitt PLoS Biol. A single-cell atlas of adult Drosophila ovary identifies transcriptional programs and somatic cell lineage regulating oogenesis. 2020-04-27 10.1371/journal.pbio.3000538 view
Koth Development Runx1 promotes scar deposition and inhibits myocardial proliferation and survival during zebrafish heart regeneration. 2020-04-27 10.1242/dev.186569 view
van Zyl Proc. Natl. Acad. Sci. U.S.A. Cell atlas of aqueous humor outflow pathways in eyes of humans and four model species provides insight into glaucoma pathogenesis. 2020-04-27 10.1073/pnas.2001250117 view
Rojahn J. Allergy Clin. Immunol. Single-cell transcriptomics combined with interstitial fluid proteomics defines cell-type-specific immune regulation in atopic dermatitis. 2020-04-25 10.1016/j.jaci.2020.03.041 view
Song bioRxiv Expression of ACE2, the SARS-CoV-2 receptor, and TMPRSS2 in prostate epithelial cells. 2020-04-25 10.1101/2020.04.24.056259 14 view
Dong BMC Bioinformatics GiniClust3: a fast and memory-efficient tool for rare cell type identification. 2020-04-25 10.1186/s12859-020-3482-1 view
Chang Molecules Induced Pluripotent Stem Cell (iPSC)-Based Neurodegenerative Disease Models for Phenotype Recapitulation and Drug Screening. 2020-04-24 10.3390/molecules25082000 view
Williams Circ. Res. Single Cell RNA Sequencing in Atherosclerosis Research. 2020-04-24 10.1161/CIRCRESAHA.119.315940 view
Song Nucleic Acids Res. Prediction of condition-specific regulatory genes using machine learning. 2020-04-24 10.1093/nar/gkaa264 view
Bauernfeind Evol. Anthropol. Metabolic changes in human brain evolution. 2020-04-24 10.1002/evan.21831 view
Darby Bioinformatics scHLAcount: Allele-specific HLA expression from single-cell gene expression data. 2020-04-24 10.1093/bioinformatics/btaa264 view
Jew Nat Commun Accurate estimation of cell composition in bulk expression through robust integration of single-cell information. 2020-04-24 10.1038/s41467-020-15816-6 view
Cautivo Curr. Opin. Immunol. Immune outposts in the adventitia: One foot in sea and one on shore. 2020-04-24 10.1016/j.coi.2020.03.005 view
Amann Int. Immunol. The origin, fate and function of macrophages in the peripheral nervous system - an update. 2020-04-23 10.1093/intimm/dxaa030 view
Abouhashem Antioxid. Redox Signal. Is Low Alveolar Type II Cell SOD3 in the Lungs of Elderly Linked to the Observed Severity of COVID-19? 2020-04-23 10.1089/ars.2020.8111 view
Huffman JCI Insight CCL5 mediates CD40-driven CD4+ T-cell tumor infiltration and immunity. 2020-04-23 10.1172/jci.insight.137263 view
Franzén Bioinformatics alona: a web server for single cell RNA-seq analysis. 2020-04-23 10.1093/bioinformatics/btaa269 view
Ye Hum. Reprod. Single-cell multiomic analysis of in vivo and in vitro matured human oocytes. 2020-04-23 10.1093/humrep/deaa044 view
Solé-Boldo Commun Biol Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming. 2020-04-23 10.1038/s42003-020-0922-4 view
Chen Lab. Invest. Identification of differentially expressed genes in lung adenocarcinoma cells using single-cell RNA sequencing not detected using traditional RNA sequencing and microarray. 2020-04-23 10.1038/s41374-020-0428-1 view
Sungnak Nat. Med. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. 2020-04-23 10.1038/s41591-020-0868-6 66 view
Wilk medRxiv A single-cell atlas of the peripheral immune response to severe COVID-19. 2020-04-23 10.1101/2020.04.17.20069930 view
Petrus-Reurer Stem Cells Transl Med Preclinical safety studies of human embryonic stem cell-derived retinal pigment epithelial cells for the treatment of age-related macular degeneration. 2020-04-22 10.1002/sctm.19-0396 view
Maxwell Sci Transl Med Gene-edited human stem cell-derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice. 2020-04-22 10.1126/scitranslmed.aax9106 view
Bahar Halpern Nat Commun Lgr5+ telocytes are a signaling source at the intestinal villus tip. 2020-04-22 10.1038/s41467-020-15714-x view
Nieuwenhuis Nat Commun Consistent RNA sequencing contamination in GTEx and other data sets. 2020-04-22 10.1038/s41467-020-15821-9 view
Satas Cell Syst SCARLET: Single-cell tumor phylogeny inference with copy-number constrained mutation losses. 2020-04-22 10.1016/j.cels.2020.04.001 view
Qiu Cells Association Analysis of Single-Cell RNA Sequencing and Proteomics Reveals a Vital Role of Ca2+ Signaling in the Determination of Skeletal Muscle Development Potential. 2020-04-22 10.3390/cells9041045 view
Wei Nature Notch signalling drives synovial fibroblast identity and arthritis pathology. 2020-04-22 10.1038/s41586-020-2222-z view
Allen Elife A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord. 2020-04-21 10.7554/eLife.54074 view
Owen EMBO Rep. Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone. 2020-04-21 10.15252/embr.202050162 view
Hor iScience Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells. 2020-04-21 10.1016/j.isci.2020.101083 view
Tsukui Nat Commun Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. 2020-04-21 10.1038/s41467-020-15647-5 8 view
Hinkel J. Am. Coll. Cardiol. AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury. 2020-04-21 10.1016/j.jacc.2020.02.041 1 view
Shang PLoS Genet. Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies. 2020-04-20 10.1371/journal.pgen.1008734 2 view
Abplanalp Cardiovasc. Res. Single cell RNA sequencing reveals profound changes in circulating immune cells in patients with heart failure. 2020-04-20 10.1093/cvr/cvaa101 3 view
Hsiao Genome Res. Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis. 2020-04-20 10.1101/gr.247759.118 view
Kallio Cancer Res. Blocking angiopoietin-2 promotes vascular damage and growth inhibition in mouse tumors treated with small doses of radiation. 2020-04-20 10.1158/0008-5472.CAN-20-0497 view
Wang Sci Rep Impacts of ciliary neurotrophic factor on the retinal transcriptome in a mouse model of photoreceptor degeneration. 2020-04-20 10.1038/s41598-020-63519-1 view
Shin Dev. Cell Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. 2020-04-20 10.1016/j.devcel.2020.03.019 view
Van Nieuwenhove J. Allergy Clin. Immunol. Defective SEC61α1 underlies a novel cause of autosomal dominant severe congenital neutropenia. 2020-04-20 10.1016/j.jaci.2020.03.034 view
Wygrecka Cell. Signal. Between life and death: Epithelial cells in lung pathologies. 2020-04-20 10.1016/j.cellsig.2020.109652 view
Chiu FASEB J. Identification of calcium and integrin-binding protein 1 as a novel regulator of production of amyloid β peptide using CRISPR/Cas9-based screening system. 2020-04-19 10.1096/fj.201902966RR view
Waickman EBioMedicine Transcriptional and clonal characterization of B cell plasmablast diversity following primary and secondary natural DENV infection. 2020-04-18 10.1016/j.ebiom.2020.102733 view
Qi Cancer Immunol. Immunother. Tumor-infiltrating CD39+CD8+ T cells determine poor prognosis and immune evasion in clear cell renal cell carcinoma patients. 2020-04-18 10.1007/s00262-020-02563-2 view
Davizon-Castillo Arterioscler. Thromb. Vasc. Biol. Megakaryocyte and Platelet Transcriptomics for Discoveries in Human Health and Disease. 2020-04-16 10.1161/ATVBAHA.119.313280 view
Krieger Neuro-oncology Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics. 2020-04-16 10.1093/neuonc/noaa091 view
Hussain FEBS J. Regulation of adipocyte thermogenesis: mechanisms controlling obesity. 2020-04-16 10.1111/febs.15331 view
Zhang Cell Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer. 2020-04-16 10.1016/j.cell.2020.03.048 view
Buschur Bioinformatics Causal network perturbations for instance-specific analysis of single cell and disease samples. 2020-04-15 10.1093/bioinformatics/btz949 view
Eisenstein Nat. Biotechnol. Publisher Correction: Single-cell RNA-seq analysis software providers scramble to offer solutions. 2020-04-15 10.1038/s41587-020-0510-7 view
Luo Neurosci Bull Single-Cell RNA Sequencing Reveals Cell-Type-Specific Mechanisms of Neurological Diseases. 2020-04-15 10.1007/s12264-020-00496-5 view
Kinaret Nanomaterials (Basel) Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects. 2020-04-15 10.3390/nano10040750 view
Shook Cell Stem Cell Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. 2020-04-15 10.1016/j.stem.2020.03.013 view
Philpott Curr Opin Chem Biol Advances and challenges in epigenomic single-cell sequencing applications. 2020-04-15 10.1016/j.cbpa.2020.01.013 view
He Elife Chloride channels regulate differentiation and barrier functions of the mammalian airway. 2020-04-14 10.7554/eLife.53085 view
Zhong Elife Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment. 2020-04-14 10.7554/eLife.54695 view
Li Nat Commun SciBet as a portable and fast single cell type identifier. 2020-04-14 10.1038/s41467-020-15523-2 view
Cano-Gamez Nat Commun Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines. 2020-04-14 10.1038/s41467-020-15543-y view
Hanamsagar Sci Rep Publisher Correction: An optimized workflow for single-cell transcriptomics and repertoire profiling of purified lymphocytes from clinical samples. 2020-04-14 10.1038/s41598-020-62066-z 1 view
Alakwaa mSystems Repurposing Didanosine as a Potential Treatment for COVID-19 Using Single-Cell RNA Sequencing Data. 2020-04-14 10.1128/mSystems.00297-20 view
Jackson-Jones Immunity Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants. 2020-04-14 10.1016/j.immuni.2020.03.011 2 view
Smith Blood Adv Diversity of peripheral blood human NK cells identified by single-cell RNA sequencing. 2020-04-14 10.1182/bloodadvances.2019000699 view
Ydens Nat. Neurosci. Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury. 2020-04-13 10.1038/s41593-020-0618-6 view
Sladitschek Cell MorphoSeq: Full Single-Cell Transcriptome Dynamics Up to Gastrulation in a Chordate. 2020-04-13 10.1016/j.cell.2020.03.055 view
Lim Cancer Cell Advancing Cancer Research and Medicine with Single-Cell Genomics. 2020-04-13 10.1016/j.ccell.2020.03.008 view
Camunas-Soler Cell Metab. Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes. 2020-04-13 10.1016/j.cmet.2020.04.005 3 view
Lavaert Immunity Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes. 2020-04-13 10.1016/j.immuni.2020.03.019 view
Wu Mol. Ther. CD39 Produced from Human GMSCs Regulates the Balance of Osteoclasts and Osteoblasts through the Wnt/β-Catenin Pathway in Osteoporosis. 2020-04-11 10.1016/j.ymthe.2020.04.003 view
Olivares-Chauvet Int. J. Biochem. Cell Biol. Inclusion of temporal information in single cell transcriptomics. 2020-04-10 10.1016/j.biocel.2020.105745 view
Wang Cells scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells. 2020-04-09 10.3390/cells9040920 20 view
Chen Stem Cell Reports Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System. 2020-04-09 10.1016/j.stemcr.2020.03.020 view
Evans Stem Cells Transl Med Alveolar wars: The rise of in vitro models to understand human lung alveolar maintenance, regeneration, and disease. 2020-04-09 10.1002/sctm.19-0433 1 view
Yu J. Leukoc. Biol. Unravelling the heterogeneity and dynamic relationships of tumor-infiltrating T cells by single-cell RNA sequencing analysis. 2020-04-09 10.1002/JLB.6MR0320-234R view
Krämer Mol Oncol Cell type-specific transcriptomics of esophageal adenocarcinoma as a scalable alternative for single cell transcriptomics. 2020-04-07 10.1002/1878-0261.12680 view
Naessens Am. J. Respir. Crit. Care Med. Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis During COPD. 2020-04-07 10.1164/rccm.201906-1123OC 2 view
Mair Cell Rep A Targeted Multi-omic Analysis Approach Measures Protein Expression and Low-Abundance Transcripts on the Single-Cell Level. 2020-04-07 10.1016/j.celrep.2020.03.063 view
Estermann Cell Rep Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo. 2020-04-07 10.1016/j.celrep.2020.03.055 view
Rohlenova Cell Metab. Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis. 2020-04-07 10.1016/j.cmet.2020.03.009 2 view
He Biochem. Biophys. Res. Commun. Adverse effects of nicotine on cardiogenic differentiation from human embryonic stem cells detected by single-cell RNA sequencing. 2020-04-07 10.1016/j.bbrc.2020.03.149 view
Fujimoto PLoS Biol. Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes. 2020-04-06 10.1371/journal.pbio.3000704 2 view
de Vries PLoS Pathog. Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response. 2020-04-06 10.1371/journal.ppat.1008408 view
Sun Stem Cell Res Ther Single-cell RNA-seq highlights heterogeneity in human primary Wharton's jelly mesenchymal stem/stromal cells cultured in vitro. 2020-04-06 10.1186/s13287-020-01660-4 view
Pine Cancer Discov Tumor microenvironment is critical for the maintenance of cellular states found in primary glioblastomas. 2020-04-06 10.1158/2159-8290.CD-20-0057 1 view
Ding Nat. Biotechnol. Systematic comparison of single-cell and single-nucleus RNA-sequencing methods. 2020-04-06 10.1038/s41587-020-0465-8 view
Dekoninck Cell Defining the Design Principles of Skin Epidermis Postnatal Growth. 2020-04-05 10.1016/j.cell.2020.03.015 view
Di Filippo Int J Mol Sci Zeb2 Regulates Myogenic Differentiation in Pluripotent Stem Cells. 2020-04-05 10.3390/ijms21072525 view
Wu Bioinformatics Joint learning dimension reduction and clustering of single-cell RNA-sequencing data. 2020-04-04 10.1093/bioinformatics/btaa231 view
Zemmour Curr. Opin. Immunol. CD4+ teff cell heterogeneity: the perspective from single-cell transcriptomics. 2020-04-04 10.1016/j.coi.2020.02.004 view
Lukassen EMBO J. SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells. 2020-04-04 10.15252/embj.20105114 view
Jun Commun Biol Single-cell analysis of a mutant library generated using CRISPR-guided deaminase in human melanoma cells. 2020-04-02 10.1038/s42003-020-0888-2 1 view
Lu J Mol Diagn Genomic Analysis of Circulating Tumor Cells at the Single-Cell Level. 2020-04-02 10.1016/j.jmoldx.2020.02.013 view
Feng Mol Metab Characterizing pancreatic β-cell heterogeneity in the streptozotocin model by single-cell transcriptomic analysis. 2020-04-02 10.1016/j.molmet.2020.100982 view
Yang J. Cell. Physiol. Long noncoding RNA 2193 regulates meiosis through global epigenetic modification and cytoskeleton organization in pig oocytes. 2020-04-02 10.1002/jcp.29675 view
Carmona Oncoimmunology Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq. 2020-04-01 10.1080/2162402X.2020.1737369 view
Ko J. Heart Lung Transplant. Single-Cell RNA-seq of Human Cardiomyocytes Revealed DNA Damage Response as a Novel Predictor for Therapeutic Prognosis in Heart Failure Patients with Dilated Cardiomyopathy. 2020-04-01 10.1016/j.healun.2020.01.1155 view
Moshkelgosha J. Heart Lung Transplant. Uncovering Salient Cellular Heterogeneity in Human Lung Transplantation Using Single-Cell RNA Sequencing. 2020-04-01 10.1016/j.healun.2020.01.1157 view
Zhao J. Heart Lung Transplant. Single Cell RNA Sequencing of Human Pulmonary Endarterectomy Specimen Reveals Distinct Cell Populations and Gene Profiles. 2020-04-01 10.1016/j.healun.2020.01.1181 view
Nykanen J. Heart Lung Transplant. Postoperative Heparinization Monitoring by Anti-Xa is More Accurate Than by APTT after Pulmonary Endarterectomy - Role of Increased Systemic and Endothelial Production of Factor VIII. 2020-04-01 10.1016/j.healun.2020.01.1184 view
Conrad J. Heart Lung Transplant. Use of Single Cell RNA Sequencing to Discern Molecular Pathways of Fibrosis and Predicting Emergence of CLAD. 2020-04-01 10.1016/j.healun.2020.01.313 view
Smirnova J. Heart Lung Transplant. Single Cell Profiling Identifies Novel B Cell Populations That Drive Chronic Rejection after Lung Transplantation. 2020-04-01 10.1016/j.healun.2020.01.022 view
van der Ven Adv. Exp. Med. Biol. Non-coding RNAs in Cardiac Regeneration. 2020-04-01 10.1007/978-981-15-1671-9_9 view
Motwani Front Immunol Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood. 2020-04-01 10.3389/fimmu.2020.00611 view
Zhang Front Immunol Association of Urine sCD163 With Proliferative Lupus Nephritis, Fibrinoid Necrosis, Cellular Crescents and Intrarenal M2 Macrophages. 2020-04-01 10.3389/fimmu.2020.00671 view
Ryan Front Genet Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection. 2020-04-01 10.3389/fgene.2020.00358 view
Zhao Cell Discov Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human. 2020-04-01 10.1038/s41421-020-0157-z view
Roulis Nature Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. 2020-04-01 10.1038/s41586-020-2166-3 view
Chen Comput Struct Biotechnol J A comparison of methods accounting for batch effects in differential expression analysis of UMI count based single cell RNA sequencing. 2020-04-01 10.1016/j.csbj.2020.03.026 view
Chavkin Front Cardiovasc Med Single Cell Analysis in Vascular Biology. 2020-04-01 10.3389/fcvm.2020.00042 view
Wu Comput Struct Biotechnol J Cellular, transcriptomic and isoform heterogeneity of breast cancer cell line revealed by full-length single-cell RNA sequencing. 2020-04-01 10.1016/j.csbj.2020.03.005 1 view
Gibellini Front Immunol Single-Cell Approaches to Profile the Response to Immune Checkpoint Inhibitors. 2020-04-01 10.3389/fimmu.2020.00490 view
Paraiso Front Cell Neurosci Isolation of Mouse Cerebral Microvasculature for Molecular and Single-Cell Analysis. 2020-04-01 10.3389/fncel.2020.00084 view
Mann Front Immunol Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System. 2020-04-01 10.3389/fimmu.2020.00633 view
Liu J Cancer Improved Prognostic Prediction of Glioblastoma using a PAS Detected from Single-cell RNA-seq. 2020-04-01 10.7150/jca.44034 view
Wang Adv Sci (Weinh) Dissolvable Polyacrylamide Beads for High-Throughput Droplet DNA Barcoding. 2020-04-01 10.1002/advs.201903463 view
van Essen PLoS Genet. Deconstructing cerebellar development cell by cell. 2020-04-01 10.1371/journal.pgen.1008630 view
Li PLoS ONE The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study. 2020-04-01 10.1371/journal.pone.0230295 70 view
Maier Nature A conserved dendritic-cell regulatory program limits antitumour immunity. 2020-04-01 10.1038/s41586-020-2134-y 1 view
Sen Sci Adv Linking indirect effects of cytomegalovirus in transplantation to modulation of monocyte innate immune function. 2020-04-01 10.1126/sciadv.aax9856 view
Barruet Elife Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. 2020-04-01 10.7554/eLife.51576 view
Zemek Nat Protoc Bilateral murine tumor models for characterizing the response to immune checkpoint blockade. 2020-04-01 10.1038/s41596-020-0299-3 view
Zand Genes (Basel) Network-Based Single-Cell RNA-Seq Data Imputation Enhances Cell Type Identification. 2020-03-31 10.3390/genes11040377 view
Wang Brief Funct Genomics Identifying cell types to interpret scRNA-seq data: how, why and more possibilities. 2020-03-31 10.1093/bfgp/elaa003 view
Zhang Nucleic Acids Res. Uncovering the key dimensions of high-throughput biomolecular data using deep learning. 2020-03-31 10.1093/nar/gkaa191 view
Chen Cell Rep Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues. 2020-03-31 10.1016/j.celrep.2020.03.012 view
Zhang Cell Rep Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog. 2020-03-31 10.1016/j.celrep.2020.03.027 view
Wagner Nat. Rev. Genet. Lineage tracing meets single-cell omics: opportunities and challenges. 2020-03-31 10.1038/s41576-020-0223-2 view
Kiss Geroscience Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain. 2020-03-31 10.1007/s11357-020-00177-1 view
Atchison Am. J. Physiol. Renal Physiol. Hypertension Induces Glomerulosclerosis in Phospholipase C Epsilon 1 Deficiency. 2020-03-30 10.1152/ajprenal.00541.2019 view
Paik Nat Rev Cardiol Single-cell RNA sequencing in cardiovascular development, disease and medicine. 2020-03-30 10.1038/s41569-020-0359-y view
Replogle Nat. Biotechnol. Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing. 2020-03-30 10.1038/s41587-020-0470-y view
Deng Aging Cell Mossy cell synaptic dysfunction causes memory imprecision via miR-128 inhibition of STIM2 in Alzheimer's disease mouse model. 2020-03-28 10.1111/acel.13144 view
Martin Curr Osteoporos Rep Transcriptomics: a Solution for Renal Osteodystrophy? 2020-03-28 10.1007/s11914-020-00583-6 view
Yu Biochim Biophys Acta Mol Basis Dis Essential gene expression pattern of head and neck squamous cell carcinoma revealed by tumor-specific expression rule based on single-cell RNA sequencing. 2020-03-28 10.1016/j.bbadis.2020.165791 view
Du G3 (Bethesda) Evaluation of STAR and Kallisto on Single Cell RNA-Seq Data Alignment. 2020-03-27 10.1534/g3.120.401160 view
Xu Nat Commun Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain. 2020-03-27 10.1038/s41467-020-15411-9 1 view
Ma Nat Commun Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies. 2020-03-27 10.1038/s41467-020-15298-6 view
Wu Nat Rev Nephrol Tools for the analysis of high-dimensional single-cell RNA sequencing data. 2020-03-27 10.1038/s41581-020-0262-0 view
Chapuy Cells Single-Cell Protein and RNA Expression Analysis of Mononuclear Phagocytes in Intestinal Mucosa and Mesenteric Lymph Nodes of Ulcerative Colitis and Crohn's Disease Patients. 2020-03-27 10.3390/cells9040813 view
Iwanaga JCI Insight Host immunology and rational immunotherapy for carbapenem-resistant Klebsiella pneumoniae infection. 2020-03-26 10.1172/jci.insight.135591 view
Peired Sci Transl Med Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells. 2020-03-25 10.1126/scitranslmed.aaw6003 view
Angerer Bioinformatics Automatic identification of relevant genes from low-dimensional embeddings of single cell RNAseq data. 2020-03-24 10.1093/bioinformatics/btaa198 view
Venkatasubramanian Bioinformatics Resolving single-cell heterogeneity from hundreds of thousands of cells through sequential hybrid clustering and NMF. 2020-03-24 10.1093/bioinformatics/btaa201 2 view
Jiang Am. J. Respir. Cell Mol. Biol. Phenotypic Diversity Caused by Differential Expression of SFTPC-Cre Transgenic Alleles. 2020-03-24 10.1165/rcmb.2019-0416MA view
Bellissimo Blood Adv Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling. 2020-03-24 10.1182/bloodadvances.2019000785 view
Greaney Cell Rep Platform Effects on Regeneration by Pulmonary Basal Cells as Evaluated by Single-Cell RNA Sequencing. 2020-03-24 10.1016/j.celrep.2020.03.004 view
Ma Plant Physiol. PscB: A Browser to Explore Plant Single Cell RNA-Sequencing Datasets. 2020-03-24 10.1104/pp.20.00250 view
Izzo Nat. Genet. DNA methylation disruption reshapes the hematopoietic differentiation landscape. 2020-03-23 10.1038/s41588-020-0595-4 1 view
Hoffman Cancers (Basel) Analysis of Dual Class I Histone Deacetylase and Lysine Demethylase Inhibitor Domatinostat (4SC-202) on Growth and Cellular and Genomic Landscape of Atypical Teratoid/Rhabdoid. 2020-03-23 10.3390/cancers12030756 view
Westoby Genome Biol. Obstacles to detecting isoforms using full-length scRNA-seq data. 2020-03-23 10.1186/s13059-020-01981-w view
Cuomo Nat Commun Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression. 2020-03-23 10.1038/s41467-020-15098-y view
Kazer Nat. Med. Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection. 2020-03-23 10.1038/s41591-020-0799-2 1 view
Feng Int J Mol Sci Dimension Reduction and Clustering Models for Single-Cell RNA Sequencing Data: A Comparative Study. 2020-03-22 10.3390/ijms21062181 2 view
Hou Cell Res. Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses. 2020-03-20 10.1038/s41422-020-0300-2 view
Yifan J. Mol. Cell. Cardiol. Visualization of cardiovascular development, physiology and disease at the single-cell level: Opportunities and future challenges. 2020-03-20 10.1016/j.yjmcc.2020.03.005 view
Oprescu iScience Temporal Dynamics and Heterogeneity of Cell Populations during Skeletal Muscle Regeneration. 2020-03-20 10.1016/j.isci.2020.100993 view
Zhang Yi Chuan Single-cell sequencing and its application in breast cancer. 2020-03-20 10.16288/j.yczz.19-268 view
Qu Yi Chuan Applications of single-cell RNA sequencing in virology. 2020-03-20 10.16288/j.yczz.19-223 view
Cabello-Aguilar Nucleic Acids Res. SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics. 2020-03-20 10.1093/nar/gkaa183 view
Smith BMC Bioinformatics Standard machine learning approaches outperform deep representation learning on phenotype prediction from transcriptomics data. 2020-03-20 10.1186/s12859-020-3427-8 view
Kimmel Development Aging induces aberrant state transition kinetics in murine muscle stem cells. 2020-03-20 10.1242/dev.183855 4 view
Kim Clin. Cancer Res. B-cells improve overall survival in HPV-associated squamous cell carcinomas and are activated by radiation and PD-1 blockade. 2020-03-19 10.1158/1078-0432.CCR-19-3211 view
Ho Protein Cell Single-cell transcriptomic analysis of adult mouse pituitary reveals sexual dimorphism and physiologic demand-induced cellular plasticity. 2020-03-19 10.1007/s13238-020-00705-x 1 view
Wang Cell Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors. 2020-03-19 10.1016/j.cell.2020.02.048 view
Duren Genome Res. Time course regulatory analysis based on paired expression and chromatin accessibility data. 2020-03-18 10.1101/gr.257063.119 view
Liang Nat Commun Latent periodic process inference from single-cell RNA-seq data. 2020-03-18 10.1038/s41467-020-15295-9 view
Ilsley Sci Rep Finding cell-specific expression patterns in the early Ciona embryo with single-cell RNA-seq. 2020-03-18 10.1038/s41598-020-61591-1 view
Wuggenig Commun Biol Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice. 2020-03-18 10.1038/s42003-020-0842-3 view
Qi Biochem. Biophys. Res. Commun. Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses. 2020-03-18 10.1016/j.bbrc.2020.03.044 view
Buchheit J. Allergy Clin. Immunol. IL-5Rα marks nasal polyp IgG4 and IgE-expressing cells in aspirin-exacerbated respiratory disease. 2020-03-18 10.1016/j.jaci.2020.02.035 view
Hess Biotechnol. Adv. Library preparation for next generation sequencing: A review of automation strategies. 2020-03-18 10.1016/j.biotechadv.2020.107537 view
Tao Prog. Neurobiol. MeCP2 mediates transgenerational transmission of chronic pain. 2020-03-18 10.1016/j.pneurobio.2020.101790 view
Zhu Proteomics Single-cell RNA Sequencing in Hematological Diseases. 2020-03-17 10.1002/pmic.201900228 view
Shrestha J. Clin. Invest. Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. 2020-03-17 10.1172/JCI134874 view
Nam Neural Dev Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life. 2020-03-17 10.1186/s13064-020-00139-5 2 view
Haensel Cell Rep Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics. 2020-03-17 10.1016/j.celrep.2020.02.091 view
Stamataki Immunology The Liver as an Immunological Barrier Redefined by Single Cell Analysis. 2020-03-16 10.1111/imm.13193 view
Basilico Nat Commun Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML. 2020-03-16 10.1038/s41467-020-15220-0 1 view
McCarthy Nat. Methods Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes. 2020-03-16 10.1038/s41592-020-0766-3 2 view
Slevin J Crohns Colitis Lymphocyte activation gene (LAG)-3 is associated with mucosal inflammation and disease activity in ulcerative colitis. 2020-03-16 10.1093/ecco-jcc/jjaa054 view
Bayraktar Nat. Neurosci. Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map. 2020-03-16 10.1038/s41593-020-0602-1 view
Lei J. Comput. Biol. Tumor Copy Number Deconvolution Integrating Bulk and Single-Cell Sequencing Data. 2020-03-16 10.1089/cmb.2019.0302 6 view
Torres Int J Mol Sci Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview. 2020-03-16 10.3390/ijms21062027 view
Suffee Circ. Res. Reactivation of the Epicardium at the Origin of Myocardial Fibro-Fatty Infiltration During the Atrial Cardiomyopathy. 2020-03-16 10.1161/CIRCRESAHA.119.316251 2 view
Svensson Bioinformatics Interpretable factor models of single-cell RNA-seq via variational autoencoders. 2020-03-16 10.1093/bioinformatics/btaa169 3 view
Hu Genome Biol Evol Significant Evolutionary Constraints on Neuron Cells Revealed by Single Cell Transcriptomics. 2020-03-16 10.1093/gbe/evaa054 view
Hum Cancers (Basel) Comparative Molecular Analysis of Cancer Behavior Cultured In Vitro, In Vivo, and Ex Vivo. 2020-03-14 10.3390/cancers12030690 view
Deng Cell. Mol. Life Sci. Single-cell gene profiling and lineage tracing analyses revealed novel mechanisms of endothelial repair by progenitors. 2020-03-13 10.1007/s00018-020-03480-4 view
Lefort Biochem. Soc. Trans. Targeting BMP signaling in the bone marrow microenvironment of myeloid leukemia. 2020-03-13 10.1042/BST20190223 view
Hoffman Commun Biol Single-cell RNA sequencing reveals a heterogeneous response to Glucocorticoids in breast cancer cells. 2020-03-13 10.1038/s42003-020-0837-0 view
Cattenoz EMBO J. Temporal specificity and heterogeneity of Drosophila immune cells. 2020-03-12 10.15252/embj.2020104486 4 view
Zheng Compr Physiol Single-Cell Transcriptomic Analysis. 2020-03-12 10.1002/cphy.c190037 view
Ha Small Mass Cytometry and Single-Cell RNA-seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles. 2020-03-12 10.1002/smll.201907674 view
Baumann Development Role of nutrient-driven O-GlcNAc-posttranslational modification in pancreatic exocrine and endocrine islet development. 2020-03-12 10.1242/dev.186643 view
Liu J. Neurosci. Res. Single-cell RNA sequencing study of retinal immune regulators identified CD47 and CD59a expression in photoreceptors-Implications in subretinal immune regulation. 2020-03-12 10.1002/jnr.24618 view
Zou Front Med Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection. 2020-03-12 10.1007/s11684-020-0754-0 view
Chen Bioinformatics RobustClone: A robust PCA method for tumor clone and evolution inference from single-cell sequencing data. 2020-03-11 10.1093/bioinformatics/btaa172 view
Ekiz J. Immunol. T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation. 2020-03-11 10.4049/jimmunol.1901484 view
Nicolet Proc. Natl. Acad. Sci. U.S.A. CD29 identifies IFN-γ-producing human CD8+ T cells with an increased cytotoxic potential. 2020-03-11 10.1073/pnas.1913940117 view
Calandrini Nat Commun An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity. 2020-03-11 10.1038/s41467-020-15155-6 view
Ediriwickrema Blood Adv Single-cell mutational profiling enhances the clinical evaluation of AML MRD. 2020-03-10 10.1182/bloodadvances.2019001181 view
Roberts Circ. Res. Deep Phenotyping by Mass Cytometry and Single Cell RNA-Sequencing Reveals LYN Regulated Signaling Profiles Underlying Monocyte Subset Heterogeneity and Lifespan. 2020-03-10 10.1161/CIRCRESAHA.119.315708 view
Alteio mSystems Complementary Metagenomic Approaches Improve Reconstruction of Microbial Diversity in a Forest Soil. 2020-03-10 10.1128/mSystems.00768-19 1 view
Chong Nat Commun Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes. 2020-03-10 10.1038/s41467-020-14968-9 view
De Micheli Cell Rep Single-Cell Analysis of the Muscle Stem Cell Hierarchy Identifies Heterotypic Communication Signals Involved in Skeletal Muscle Regeneration. 2020-03-10 10.1016/j.celrep.2020.02.067 view
Liu Micromachines (Basel) Cell Lysis Based on an Oscillating Microbubble Array. 2020-03-10 10.3390/mi11030288 view
Zou Cancers (Basel) Molecular Heterogeneity and Cellular Diversity: Implications for Precision Treatment in Medulloblastoma. 2020-03-10 10.3390/cancers12030643 view
Fang IEEE/ACM Trans Comput Biol Bioinform An Effective Biclustering-based Framework for Identifying Cell Subpopulations from scRNA-seq Data. 2020-03-10 10.1109/TCBB.2020.2979717 view
Wakhloo Nat Commun Functional hypoxia drives neuroplasticity and neurogenesis via brain erythropoietin. 2020-03-09 10.1038/s41467-020-15041-1 view
Tsuyuzaki Nat Commun Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast. 2020-03-09 10.1038/s41467-020-15060-y view
Giladi Nat. Biotechnol. Dissecting cellular crosstalk by sequencing physically interacting cells. 2020-03-09 10.1038/s41587-020-0442-2 view
van der Wijst Elife The single-cell eQTLGen consortium. 2020-03-09 10.7554/eLife.52155 view
Fu J Genet Genomics Single-cell RNA sequencing identifies novel cell types in Drosophila blood. 2020-03-09 10.1016/j.jgg.2020.02.004 view
Terkelsen Hepatology Transcriptional dynamics of hepatic sinusoid-associated cells after liver injury. 2020-03-07 10.1002/hep.31215 view
Chung Bioinformatics Statistical significance of cluster membership for unsupervised evaluation of single cell identities. 2020-03-06 10.1093/bioinformatics/btaa087 view
Ryan Stem Cell Reports Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection. 2020-03-06 10.1016/j.stemcr.2020.02.010 view
Zhu Hum. Gene Ther. Single-Cell Transcriptome Analysis of Mouse Liver Cell-Specific Tropism and Transcriptional Dysregulation Following Intravenous Administration of AAVrh.10 Vectors. 2020-03-06 10.1089/hum.2019.366 view
Künzli Sci Immunol Long-lived T follicular helper cells retain plasticity and help sustain humoral immunity. 2020-03-06 10.1126/sciimmunol.aay5552 9 view
Yang Genome Biol. Decontamination of ambient RNA in single-cell RNA-seq with DecontX. 2020-03-05 10.1186/s13059-020-1950-6 view
Van den Berge Nat Commun Trajectory-based differential expression analysis for single-cell sequencing data. 2020-03-05 10.1038/s41467-020-14766-3 view
Batiuk Nat Commun Identification of region-specific astrocyte subtypes at single cell resolution. 2020-03-05 10.1038/s41467-019-14198-8 1 view
Tirosh Cell Stem Cell Tackling the Many Facets of Glioblastoma Heterogeneity. 2020-03-05 10.1016/j.stem.2020.02.005 view
Chang Cancer Epidemiol. Biomarkers Prev. Environmental Carcinogenesis at the Single Cell Level. 2020-03-04 10.1158/1055-9965.EPI-19-1364 view
Xu Stem Cells Genome-Wide CRISPR Screen Identifies ZIC2 As An Essential Gene That Controls The Cell-Fate of Early Mesodermal Precursors To Human Heart Progenitors. 2020-03-04 10.1002/stem.3168 view
Anderson Cell Rep Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development. 2020-03-03 10.1016/j.celrep.2020.02.030 1 view
Ozaki BMC Genomics Millefy: visualizing cell-to-cell heterogeneity in read coverage of single-cell RNA sequencing datasets. 2020-03-03 10.1186/s12864-020-6542-z 3 view
Qiu Nat Commun Embracing the dropouts in single-cell RNA-seq analysis. 2020-03-03 10.1038/s41467-020-14976-9 7 view
Azad Hepatology Targeted Apoptosis Of Ductular Reactive Cells Reduces Hepatic Fibrosis In A Mouse Model of Cholestasis. 2020-03-03 10.1002/hep.31211 view
Byrne J. Exp. Med. Dynamics of human monocytes and airway macrophages during healthy aging and after transplant. 2020-03-02 10.1084/jem.20191236 3 view
Chen J. Exp. Med. Re-evaluation of human BDCA-2+ DC during acute sterile skin inflammation. 2020-03-02 10.1084/jem.20190811 view
Chen Bioinformatics scRMD: Imputation for single cell RNA-seq data via robust matrix decomposition. 2020-03-02 10.1093/bioinformatics/btaa139 view
Lawlor Bioinformatics V-SVA: an R Shiny application for detecting and annotating hidden sources of variation in single cell RNA-seq data. 2020-03-02 10.1093/bioinformatics/btaa128 view
Davies Annu Rev Genomics Hum Genet The Long Journey from Diagnosis to Therapy. 2020-03-02 10.1146/annurev-genom-112019-083518 view
Ghaedi J. Exp. Med. Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets. 2020-03-02 10.1084/jem.20182293 4 view
Montoro Cold Spring Harb Perspect Biol A Synthesis Concerning Conservation and Divergence of Cell Types across Epithelia. 2020-03-02 10.1101/cshperspect.a035733 view
Gorick Proc. Natl. Acad. Sci. U.S.A. Sonoselective transfection of cerebral vasculature without blood-brain barrier disruption. 2020-03-02 10.1073/pnas.1914595117 1 view
Schwartz Nat. Methods TooManyCells identifies and visualizes relationships of single-cell clades. 2020-03-02 10.1038/s41592-020-0748-5 view
Tomoiaga NPJ Genom Med Single-cell sperm transcriptomes and variants from fathers of children with and without autism spectrum disorder. 2020-03-01 10.1038/s41525-020-0117-4 view
Mashkaryan Front Cell Dev Biol Type 1 Interleukin-4 Signaling Obliterates Mouse Astroglia in vivo but Not in vitro. 2020-03-01 10.3389/fcell.2020.00114 view
Eisenstein Nat. Biotechnol. Single-cell RNA-seq analysis software providers scramble to offer solutions. 2020-03-01 10.1038/s41587-020-0449-8 view
Zhang Front Oncol Corrigendum: The Tumor Suppressor Role of Zinc Finger Protein 671 (ZNF671) in Multiple Tumors Based on Cancer Single-Cell Sequencing. 2020-03-01 10.3389/fonc.2020.00339 view
Gay Sci Adv Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing. 2020-03-01 10.1126/sciadv.aay3704 view
Abidi Front Immunol Characterization of Rat ILCs Reveals ILC2 as the Dominant Intestinal Subset. 2020-03-01 10.3389/fimmu.2020.00255 view
Peng RNA Biol Single-cell RNA-seq clustering: datasets, models, and algorithms. 2020-03-01 10.1080/15476286.2020.1728961 view
Wang Int. J. Biol. Sci. Single-cell RNA-sequencing analysis identifies host long noncoding RNA MAMDC2-AS1 as a co-factor for HSV-1 nuclear transport. 2020-03-01 10.7150/ijbs.42556 view
Hoa Front Mol Neurosci Characterizing Adult Cochlear Supporting Cell Transcriptional Diversity Using Single-Cell RNA-Seq: Validation in the Adult Mouse and Translational Implications for the Adult Human Cochlea. 2020-03-01 10.3389/fnmol.2020.00013 view
Liang Theranostics CD8+ T-cell plasticity regulates vascular regeneration in type-2 diabetes. 2020-03-01 10.7150/thno.40663 3 view
Yang Front Genet High-Throughput Transcriptome Profiling in Drug and Biomarker Discovery. 2020-03-01 10.3389/fgene.2020.00019 view
Lytal Front Genet Normalization Methods on Single-Cell RNA-seq Data: An Empirical Survey. 2020-03-01 10.3389/fgene.2020.00041 view
Xiao Oncoimmunology Metabolism in the tumor microenvironment: insights from single-cell analysis. 2020-03-01 10.1080/2162402X.2020.1726556 view
Obermayer PeerJ SCelVis: exploratory single cell data analysis on the desktop and in the cloud. 2020-03-01 10.7717/peerj.8607 view
Xing Front Bioeng Biotechnol Dynamic Alternative Splicing During Mouse Preimplantation Embryo Development. 2020-03-01 10.3389/fbioe.2020.00035 view
Attaf Front Immunol FB5P-seq: FACS-Based 5-Prime End Single-Cell RNA-seq for Integrative Analysis of Transcriptome and Antigen Receptor Repertoire in B and T Cells. 2020-03-01 10.3389/fimmu.2020.00216 view
Murray Front Immunol Myeloid Cells Enriched for a Dendritic Cell Population From People Living With HIV Have Altered Gene Expression Not Restored by Antiretroviral Therapy. 2020-03-01 10.3389/fimmu.2020.00261 view
Zhao Theranostics Alginate oligosaccharides improve germ cell development and testicular microenvironment to rescue busulfan disrupted spermatogenesis. 2020-03-01 10.7150/thno.43189 view
Cheng Front Bioeng Biotechnol Identification and Analysis of Glioblastoma Biomarkers Based on Single Cell Sequencing. 2020-03-01 10.3389/fbioe.2020.00167 view
Thibaut Nat Cancer Bystander IFN-γ activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment. 2020-03-01 10.1038/s43018-020-0038-2 view
Saygin Pulm Circ Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension. 2020-03-01 10.1177/2045894020908782 view
Badsha Quant Biol Imputation of single-cell gene expression with an autoencoder neural network. 2020-03-01 10.1007/s40484-019-0192-7 view
Racle Methods Mol. Biol. EPIC: A Tool to Estimate the Proportions of Different Cell Types from Bulk Gene Expression Data. 2020-03-01 10.1007/978-1-0716-0327-7_17 view
Liu Kidney360 Profiling APOL1 Nephropathy Risk Variants in Genome-Edited Kidney Organoids with Single-Cell Transcriptomics. 2020-03-01 10.34067/kid.0000422019 view
Davis Nat. Cell Biol. Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing. 2020-03-01 10.1038/s41556-020-0477-0 10 view
Turki Comput. Biol. Med. SCGRNs: Novel supervised inference of single-cell gene regulatory networks of complex diseases. 2020-03-01 10.1016/j.compbiomed.2020.103656 view
Tieng Front Pharmacol Single Cell Transcriptome in Colorectal Cancer-Current Updates on Its Application in Metastasis, Chemoresistance and the Roles of Circulating Tumor Cells. 2020-03-01 10.3389/fphar.2020.00135 view
Tian Cell Biosci Alternative splicing signatures in preimplantation embryo development. 2020-03-01 10.1186/s13578-020-00399-y view
Fisher Cancer Discov Unraveling the Architecture of Classic Hodgkin Lymphoma One Cell at a Time. 2020-03-01 10.1158/2159-8290.CD-19-1538 view
Kokkaliaris Curr Opin Oncol Dissecting the spatial bone marrow microenvironment of hematopoietic stem cells. 2020-03-01 10.1097/CCO.0000000000000605 view
Zhu Bioinformatics 2DImpute: Imputation in Single Cell RNA-Seq Data from Correlations in Two Dimensions. 2020-02-28 10.1093/bioinformatics/btaa148 view
Wang Genome Med A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles. 2020-02-28 10.1186/s13073-020-0720-0 1 view
Lu Mucosal Immunol IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia. 2020-02-28 10.1038/s41385-020-0273-y view
Deng Chin. Med. J. Single-cell RNA sequencing data suggest a role for angiotensin-converting enzyme 2 in kidney impairment in patients infected with 2019-nCoV. 2020-02-28 10.1097/CM9.0000000000000783 view
Wang Bioinformatics Ensemble learning for classifying single-cell data and projection across reference atlases. 2020-02-27 10.1093/bioinformatics/btaa137 view
Menon JCI Insight Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker. 2020-02-27 10.1172/jci.insight.133267 view
Zhang PLoS Pathog. Two waves of pro-inflammatory factors are released during the influenza A virus (IAV)-driven pulmonary immunopathogenesis. 2020-02-26 10.1371/journal.ppat.1008334 view
Chen Exp. Lung Res. TGF-β1 increases sialidase 3 expression in human lung epithelial cells by decreasing its degradation and upregulating its translation. 2020-02-26 10.1080/01902148.2020.1733135 view
Wu Nature Peripheral T cell expansion predicts tumour infiltration and clinical response. 2020-02-26 10.1038/s41586-020-2056-8 view
Efremova Nat Protoc CellPhoneDB: inferring cell-cell communication from combined expression of multi-subunit ligand-receptor complexes. 2020-02-26 10.1038/s41596-020-0292-x 3 view
Liang Cell Stem Cell Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency. 2020-02-26 10.1016/j.stem.2020.01.013 2 view
Cai EBioMedicine Single-cell transcriptomics of blood reveals a natural killer cell subset depletion in tuberculosis. 2020-02-26 10.1016/j.ebiom.2020.102686 2 view
Zhang Aging (Albany NY) Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality. 2020-02-25 10.18632/aging.102864 view
M Genes (Basel) Estimating the Allele-Specific Expression of SNVs From 10× Genomics Single-Cell RNA-Sequencing Data. 2020-02-25 10.3390/genes11030240 view
Gu Environ. Sci. Technol. Single-cell RNA sequencing reveals size-dependent effects of polystyrene microplastics on immune and secretory cell populations from zebrafish intestines. 2020-02-24 10.1021/acs.est.9b06386 view
Zhang Genome Biol. Linked optical and gene expression profiling of single cells at high-throughput. 2020-02-24 10.1186/s13059-020-01958-9 view
Holowiecki Development Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation. 2020-02-24 10.1242/dev.185652 view
Tambalo Development A single cell transcriptome atlas of the developing zebrafish hindbrain. 2020-02-24 10.1242/dev.184143 view
Goel Proc. Natl. Acad. Sci. U.S.A. Interferon lambda promotes immune dysregulation and tissue inflammation in TLR7-induced lupus. 2020-02-24 10.1073/pnas.1916897117 view
Ge Proc. Natl. Acad. Sci. U.S.A. The aging skin microenvironment dictates stem cell behavior. 2020-02-24 10.1073/pnas.1901720117 view
Hogrebe Nat. Biotechnol. Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells. 2020-02-24 10.1038/s41587-020-0430-6 14 view
Tiraboschi Epilepsia New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome. 2020-02-24 10.1111/epi.16456 view
Lord Dev. Cell Metabolic Changes Accompanying Spermatogonial Stem Cell Differentiation. 2020-02-24 10.1016/j.devcel.2020.01.014 view
Johnson Dev. Cell Cellular Heterogeneity and Lineage Restriction during Mouse Digit Tip Regeneration at Single-Cell Resolution. 2020-02-24 10.1016/j.devcel.2020.01.026 view
Zhu Interdiscip Sci Single-Cell Clustering Based on Shared Nearest Neighbor and Graph Partitioning. 2020-02-22 10.1007/s12539-019-00357-4 view
Mangolini Int J Mol Sci Bone Marrow Stromal Cells Drive Key Hallmarks of B Cell Malignancies. 2020-02-21 10.3390/ijms21041466 view
Park Science A cell atlas of human thymic development defines T cell repertoire formation. 2020-02-21 10.1126/science.aay3224 view
Wilkinson Sci Rep Persistent features of intermittent transcription. 2020-02-21 10.1038/s41598-020-60094-3 view
Joshi J. Leukoc. Biol. Frontline Science: Cxxc5 expression alters cell cycle and myeloid differentiation of mouse hematopoietic stem and progenitor cells. 2020-02-21 10.1002/JLB.1HI0120-169R view
Lin BMC Bioinformatics A deep adversarial variational autoencoder model for dimensionality reduction in single-cell RNA sequencing analysis. 2020-02-21 10.1186/s12859-020-3401-5 view
Alshetaiwi Sci Immunol Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics. 2020-02-21 10.1126/sciimmunol.aay6017 view
Giacobassi Proc. Natl. Acad. Sci. U.S.A. An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses. 2020-02-20 10.1073/pnas.1911382117 view
Traniello Sci Rep Meta-analysis of honey bee neurogenomic response links Deformed wing virus type A to precocious behavioral maturation. 2020-02-20 10.1038/s41598-020-59808-4 view
Wolf J Cardiovasc Transl Res Atherosclerosis: Insights into Vascular Pathobiology and Outlook to Novel Treatments. 2020-02-19 10.1007/s12265-020-09961-y view
Guo J. Pathol. Characteristics, dynamic changes, and prognostic significance of TCR repertoire profiling in renal cell carcinoma patients. 2020-02-19 10.1002/path.5396 view
Hakes Elife Tailless/TLX reverts intermediate neural progenitors to stem cells driving tumourigenesis via repression of asense/ASCL1. 2020-02-19 10.7554/eLife.53377 view
Jin Bioinformatics scTSSR: gene expression recovery for single-cell RNA sequencing using two-side sparse self-representation. 2020-02-19 10.1093/bioinformatics/btaa108 view
Xu Bioinformatics CMF-Impute: An accurate imputation tool for single cell RNA-seq data. 2020-02-19 10.1093/bioinformatics/btaa109 view
van den Brink Nature Single-cell and spatial transcriptomics reveal somitogenesis in gastruloids. 2020-02-19 10.1038/s41586-020-2024-3 view
Lin PLoS Comput. Biol. Inferring TF activation order in time series scRNA-Seq studies. 2020-02-18 10.1371/journal.pcbi.1007644 view
Lopes BMC Bioinformatics Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data. 2020-02-18 10.1186/s12859-020-3390-4 2 view
Samir BMC Med Genomics Exploring and analysing single cell multi-omics data with VDJView. 2020-02-18 10.1186/s12920-020-0696-z 1 view
Dicks Stem Cell Res Ther Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter. 2020-02-18 10.1186/s13287-020-01597-8 view
Iemolo J. Comp. Neurol. A cell type-specific expression map of NCoR1 and SMRT transcriptional co-repressors in the mouse brain. 2020-02-18 10.1002/cne.24886 view
Suenkel Cell Rep A Highly Conserved Circular RNA Is Required to Keep Neural Cells in a Progenitor State in the Mammalian Brain. 2020-02-18 10.1016/j.celrep.2020.01.083 view
Jorstad Cell Rep STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina. 2020-02-18 10.1016/j.celrep.2020.01.075 view
Pasquini Int J Mol Sci Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in vivo Genome Editing. 2020-02-18 10.3390/ijms21041380 2 view
Tsakmaki Mol Metab ISX-9 manipulates endocrine progenitor fate revealing conserved intestinal lineages in mouse and human organoids. 2020-02-17 10.1016/j.molmet.2020.01.012 view
Xue Elife A single-parasite transcriptional atlas of Toxoplasma gondii reveals novel control of antigen expression. 2020-02-17 10.7554/eLife.54129 1 view
Assefa Bioinformatics SPsimSeq: semi-parametric simulation of bulk and single cell RNA sequencing data. 2020-02-17 10.1093/bioinformatics/btaa105 view
Fendler Nat Commun Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients. 2020-02-17 10.1038/s41467-020-14700-7 view
Reyes Nat. Med. An immune-cell signature of bacterial sepsis. 2020-02-17 10.1038/s41591-020-0752-4 1 view
Wen Nat. Neurosci. Spatiotemporal single-cell analysis of gene expression in the mouse suprachiasmatic nucleus. 2020-02-17 10.1038/s41593-020-0586-x view
Durante Nat. Neurosci. Single-cell analysis of olfactory neurogenesis and differentiation in adult humans. 2020-02-17 10.1038/s41593-020-0587-9 view
Marisca Nat. Neurosci. Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation. 2020-02-17 10.1038/s41593-019-0581-2 10 view
Xie Biomolecules Kernel Differential Subgraph Analysis to Reveal the Key Period Affecting Glioblastoma. 2020-02-17 10.3390/biom10020318 view
Chen Cancer Biol Med The role of bone marrow-derived cells in the origin of liver cancer revealed by single-cell sequencing. 2020-02-15 10.20892/j.issn.2095-3941.2019.0369 view
Joost Cell Stem Cell The Molecular Anatomy of Mouse Skin during Hair Growth and Rest. 2020-02-15 10.1016/j.stem.2020.01.012 view
Sathe Clin. Cancer Res. Single cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment. 2020-02-14 10.1158/1078-0432.CCR-19-3231 2 view
Boufea iScience scID Uses Discriminant Analysis to Identify Transcriptionally Equivalent Cell Types across Single-Cell RNA-Seq Data with Batch Effect. 2020-02-14 10.1016/j.isci.2020.100914 view
Rondini Biochem. J. Single cell approaches to address adipose tissue stromal cell heterogeneity. 2020-02-14 10.1042/BCJ20190467 view
McCarthy Cell Stem Cell Distinct Mesenchymal Cell Populations Generate the Essential Intestinal BMP Signaling Gradient. 2020-02-14 10.1016/j.stem.2020.01.008 3 view
Murata Cell Stem Cell Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells. 2020-02-14 10.1016/j.stem.2019.12.011 view
Rees J. Leukoc. Biol. How do immune and mesenchymal cells influence the intestinal epithelial cell compartment in inflammatory bowel disease? Let's crosstalk about it! 2020-02-14 10.1002/JLB.3MIR0120-567R view
Cao Bioinformatics GeneSwitches: Ordering gene-expression and functional events in single-cell experiments. 2020-02-14 10.1093/bioinformatics/btaa099 view
Zhao Cancer Lett. Single cell RNA-seq reveals the landscape of tumor and infiltrating immune cells in nasopharyngeal cancer. 2020-02-13 10.1016/j.canlet.2020.02.010 view
Voigt Cells Single-Cell RNA Sequencing in Human Retinal Degeneration Reveals Distinct Glial Cell Populations. 2020-02-13 10.3390/cells9020438 view
do Valle Duraes JCI Insight Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis. 2020-02-13 10.1172/jci.insight.130651 view
Liang Mol Ther Nucleic Acids Machine Learning of Single-Cell Transcriptome Highly Identifies mRNA Signature by Comparing F-Score Selection with DGE Analysis. 2020-02-13 10.1016/j.omtn.2020.02.004 view
Zhang Bioinformatics ZIAQ: A quantile regression method for differential expression analysis of single-cell RNA-seq data. 2020-02-13 10.1093/bioinformatics/btaa098 view
Fei Bioinformatics scBatch: Batch Effect Correction of RNA-seq Data through Sample Distance Matrix Adjustment. 2020-02-13 10.1093/bioinformatics/btaa097 view
Rao Cold Spring Harb Mol Case Stud Comparative scRNA-seq Reveals Liver Metastasis-Specific Targets in a Patient with Small Intestinal Neuroendocrine Cancer. 2020-02-13 10.1101/mcs.a004978 view
Weinberger Dev. Cell Functional Heterogeneity within the Developing Zebrafish Epicardium. 2020-02-12 10.1016/j.devcel.2020.01.023 2 view
Tarca BMC Med Genomics Amniotic fluid cell-free transcriptome: a glimpse into fetal development and placental cellular dynamics during normal pregnancy. 2020-02-12 10.1186/s12920-020-0690-5 view
Holland Genome Biol. Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data. 2020-02-12 10.1186/s13059-020-1949-z view
Zhou Proc. Natl. Acad. Sci. U.S.A. Occludin protects secretory cells from ER stress by facilitating SNARE-dependent apical protein exocytosis. 2020-02-12 10.1073/pnas.1909731117 view
Dang Mol. Psychiatry Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids. 2020-02-12 10.1038/s41380-020-0676-x view
Norimoto Nature A claustrum in reptiles and its role in slow-wave sleep. 2020-02-12 10.1038/s41586-020-1993-6 2 view
Wheeler Nature MAFG-driven astrocytes promote CNS inflammation. 2020-02-12 10.1038/s41586-020-1999-0 3 view
Kong Nat Protoc CellTagging: combinatorial indexing to simultaneously map lineage and identity at single-cell resolution. 2020-02-12 10.1038/s41596-019-0247-2 4 view
Wang Stem Cell Reports Adult Human Glioblastomas Harbor Radial Glia-like Cells. 2020-02-11 10.1016/j.stemcr.2020.01.007 2 view
Aynaud Cell Rep Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution. 2020-02-11 10.1016/j.celrep.2020.01.049 view
Kalucka Cell Single-Cell Transcriptome Atlas of Murine Endothelial Cells. 2020-02-10 10.1016/j.cell.2020.01.015 7 view
LeBleu FASEB J. Origin and functional heterogeneity of fibroblasts. 2020-02-10 10.1096/fj.201903188R view
Walker J Transl Med CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq. 2020-02-10 10.1186/s12967-020-02247-6 1 view
Fu Aging (Albany NY) Single-cell RNA sequencing of immune cells in gastric cancer patients. 2020-02-10 10.18632/aging.102774 view
Tallquist Annu. Rev. Physiol. Cardiac Fibroblast Diversity. 2020-02-10 10.1146/annurev-physiol-021119-034527 2 view
Andersson Cancer Res. Extensive clonal branching shapes the evolutionary history of high-risk pediatric cancers. 2020-02-10 10.1158/0008-5472.CAN-19-3468 view
Chandra Cancer Res. Clonal ZEB1-driven mesenchymal transition promotes targetable oncologic anti-angiogenic therapy resistance. 2020-02-10 10.1158/0008-5472.CAN-19-1305 view
Cuomo Nat Commun Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression. 2020-02-10 10.1038/s41467-020-14457-z view
Hanamsagar Sci Rep An optimized workflow for single-cell transcriptomics and repertoire profiling of purified lymphocytes from clinical samples. 2020-02-10 10.1038/s41598-020-58939-y 1 view
Fairfax Nat. Med. Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma. 2020-02-10 10.1038/s41591-019-0734-6 view
Hu Cancer Cell The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells. 2020-02-10 10.1016/j.ccell.2020.01.003 3 view
Lähnemann Genome Biol. Eleven grand challenges in single-cell data science. 2020-02-07 10.1186/s13059-020-1926-6 2 view
Hanchate Proc. Natl. Acad. Sci. U.S.A. Connect-seq to superimpose molecular on anatomical neural circuit maps. 2020-02-07 10.1073/pnas.1912176117 view
Zhang Nat Commun Determining sequencing depth in a single-cell RNA-seq experiment. 2020-02-07 10.1038/s41467-020-14482-y view
Kozak Curr. Biol. Epithelial Planar Bipolarity Emerges from Notch-Mediated Asymmetric Inhibition of Emx2. 2020-02-07 10.1016/j.cub.2020.01.027 view
Schwabe Gastroenterology Mechanisms of Fibrosis Development in NASH. 2020-02-07 10.1053/j.gastro.2019.11.311 1 view
Chen Stem Cell Reports High-Resolution Dissection of Chemical Reprogramming from Mouse Embryonic Fibroblasts into Fibrocartilaginous Cells. 2020-02-07 10.1016/j.stemcr.2020.01.013 view
Ye J Genet Genomics Defining endogenous barcoding sites for CRISPR/Cas9-based cell lineage tracing in zebrafish. 2020-02-07 10.1016/j.jgg.2019.11.012 view
Posada Mol. Biol. Evol. CellCoal: coalescent simulation of single-cell sequencing samples. 2020-02-06 10.1093/molbev/msaa025 view
Kim Sci Rep Robust RNA-Seq of aRNA-amplified single cell material collected by patch clamp. 2020-02-06 10.1038/s41598-020-58715-y view
Jue Sci Rep Two-phase wash to solve the ubiquitous contaminant-carryover problem in commercial nucleic-acid extraction kits. 2020-02-06 10.1038/s41598-020-58586-3 view
Li Neuropharmacology The hypocretin (orexin) system: from a neural circuitry perspective. 2020-02-06 10.1016/j.neuropharm.2020.107993 view
Li IEEE/ACM Trans Comput Biol Bioinform Evolving Transcriptomic Profiles from Single-cell RNA-seq Data using Nature-Inspired Multiobjective Optimization. 2020-02-06 10.1109/TCBB.2020.2971993 view
He J. Allergy Clin. Immunol. Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. 2020-02-06 10.1016/j.jaci.2020.01.042 view
Vila Ellis Dev. Cell Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. 2020-02-04 10.1016/j.devcel.2020.01.009 view
Shao iScience scCATCH: Automatic Annotation on Cell Types of Clusters from Single-Cell RNA Sequencing Data. 2020-02-04 10.1016/j.isci.2020.100882 3 view
Masuda Cell Rep Microglia Heterogeneity in the Single-Cell Era. 2020-02-04 10.1016/j.celrep.2020.01.010 11 view
Ali Cell Rep Cell Lineage Tracing Identifies Hormone-Regulated and Wnt-Responsive Vaginal Epithelial Stem Cells. 2020-02-04 10.1016/j.celrep.2020.01.003 view
Yartseva Cell Rep Heterogeneity of Satellite Cells Implicates DELTA1/NOTCH2 Signaling in Self-Renewal. 2020-02-04 10.1016/j.celrep.2019.12.100 1 view
Sridhar Cell Rep Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures. 2020-02-04 10.1016/j.celrep.2020.01.007 view
Sui J. Cell. Physiol. Inhibition of HDAC6 by tubastatin A disrupts mouse oocyte meiosis via regulating histone modifications and mRNA expression. 2020-02-04 10.1002/jcp.29599 view
Janssen Cancer Immunol Res γδ T-cell receptors derived from breast cancer-infiltrating T lymphocytes mediate antitumor reactivity. 2020-02-04 10.1158/2326-6066.CIR-19-0513 2 view
Li Curr. Biol. Single-Cell Transcriptomes Reveal Diverse Regulatory Strategies for Olfactory Receptor Expression and Axon Targeting. 2020-02-03 10.1016/j.cub.2020.01.049 view
He J. Exp. Med. Atlas of the human intestine. 2020-02-03 10.1084/jem.20191997 view
Jophlin Hepatology The transcriptome of hepatic fibrosis revealed by single cell RNA sequencing. 2020-02-03 10.1002/hep.31155 view
Moshkovskii Biochemistry Mosc. Single Cell Proteogenomics - Immediate Prospects. 2020-02-01 10.1134/S0006297920020029 view
Siegel Trends Parasitol. Single cell sequencing shines a light on malaria parasite relatedness in complex infections. 2020-02-01 10.1016/ 1 view
Wen Comput Struct Biotechnol J Technological advances and computational approaches for alternative splicing analysis in single cells. 2020-02-01 10.1016/j.csbj.2020.01.009 view
Maehara J Korean Assoc Oral Maxillofac Surg Review of a novel disease entity, immunoglobulin G4-related disease. 2020-02-01 10.5125/jkaoms.2020.46.1.3 view
Sachs Nat Metab Targeted pharmacological therapy restores β-cell function for diabetes remission. 2020-02-01 10.1038/s42255-020-0171-3 view
Zong PLoS ONE Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering. 2020-02-01 10.1371/journal.pone.0228112 view
Carr Front Med (Lausanne) New Developments in Transcriptomic Analysis of Synovial Tissue. 2020-02-01 10.3389/fmed.2020.00021 view
Ha Heliyon Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer. 2020-02-01 10.1016/j.heliyon.2020.e03350 view
Sidhaye Am. J. Respir. Cell Mol. Biol. Jumping on the Single-Cell RNA-Sequencing Bandwagon: Take Care Not to Put the Cart before the Horse. 2020-02-01 10.1165/rcmb.2019-0389LE view
Deeke J Bioinform Comput Biol Stably expressed genes in single-cell RNA sequencing. 2020-02-01 10.1142/S0219720020400041 1 view
Wen Ann Transl Med Single-cell transcriptomics reveals the alteration of peripheral blood mononuclear cells driven by sepsis. 2020-02-01 10.21037/atm.2020.02.35 1 view
Yan Oncol Lett Tracking the important role of JUNB in hepatocellular carcinoma by single-cell sequencing analysis. 2020-02-01 10.3892/ol.2019.11235 view
Willemsen J. Pathol. Macrophage subsets in atherosclerosis as defined by single-cell technologies. 2020-01-31 10.1002/path.5392 view
Zhou Nat Commun Surface protein imputation from single cell transcriptomes by deep neural networks. 2020-01-31 10.1038/s41467-020-14391-0 view
Mallampalli JCI Insight Cigarette smoke exposure enhances transforming acidic coiled-coil-containing protein 2 turnover and thereby promotes emphysema. 2020-01-30 10.1172/jci.insight.125895 view
Xiong Hepatology A single-cell perspective of the mammalian liver in health and disease. 2020-01-30 10.1002/hep.31149 view
Jeanpierre Haematologica The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission. 2020-01-30 10.3324/haematol.2019.232793 view
Selewa Sci Rep Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation. 2020-01-30 10.1038/s41598-020-58327-6 6 view
Yamada Biochem. Biophys. Res. Commun. Tissue substructure-specific deposition of the β3-containing laminin-332 in the biliary epithelium of human and mouse livers. 2020-01-30 10.1016/j.bbrc.2020.01.104 view
Alberio Theriogenology Untangling early embryo development using single cell genomics. 2020-01-30 10.1016/j.theriogenology.2020.01.062 view
Turgeon J. Immunol. Epigenetic Heterogeneity and Mitotic Heritability Prime Endothelial Cell Gene Induction. 2020-01-29 10.4049/jimmunol.1900744 view
Oatley Nat Commun Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition. 2020-01-29 10.1038/s41467-019-14171-5 view
Buono Bioessays Retina Development in Vertebrates: Systems Biology Approaches to Understanding Genetic Programs: On the Contribution of Next-Generation Sequencing Methods to the Characterization of the Regulatory Networks Controlling Vertebrate Eye Development. 2020-01-29 10.1002/bies.201900187 view
McBride J. Pathol. Radiation-Induced Tissue Damage and Response. 2020-01-28 10.1002/path.5389 1 view
Kurial Hepatology Transcriptomic traces of adult human liver progenitor cells. 2020-01-28 10.1002/hep.31143 view
Wu Clin J Am Soc Nephrol Single Cell Sequencing and Kidney Organoids Generated from Pluripotent Stem Cells. 2020-01-28 10.2215/CJN.07470619 view
Elyanow Genome Res. netNMF-sc: leveraging gene-gene interactions for imputation and dimensionality reduction in single-cell expression analysis. 2020-01-28 10.1101/gr.251603.119 view
Wan Genome Res. SHARP: hyper-fast and accurate processing of single-cell RNA-seq data via ensemble random projection. 2020-01-28 10.1101/gr.254557.119 view
Wolfien Cells Single-Nucleus Sequencing of an Entire Mammalian Heart: Cell Type Composition and Velocity. 2020-01-28 10.3390/cells9020318 view
Domingues Elife Loss of Kat2a enhances transcriptional noise and depletes acute myeloid leukaemia stem-like cells. 2020-01-27 10.7554/eLife.51754 view
Jackson Elife Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments. 2020-01-27 10.7554/eLife.51254 3 view
Mullokandov Proc. Natl. Acad. Sci. U.S.A. High-complexity extracellular barcoding using a viral hemagglutinin. 2020-01-27 10.1073/pnas.1919182117 view
McGinn Oncogene Cytokeratin 5 alters β-catenin dynamics in breast cancer cells. 2020-01-27 10.1038/s41388-020-1164-0 view
Flores Nat Nanotechnol Pro-efferocytic nanoparticles are specifically taken up by lesional macrophages and prevent atherosclerosis. 2020-01-27 10.1038/s41565-019-0619-3 6 view
Hurley Cell Stem Cell Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors. 2020-01-27 10.1016/j.stem.2019.12.009 view
Gulati Science Single-cell transcriptional diversity is a hallmark of developmental potential. 2020-01-24 10.1126/science.aax0249 4 view
Yang Genome Biol. scMAGeCK links genotypes with multiple phenotypes in single-cell CRISPR screens. 2020-01-24 10.1186/s13059-020-1928-4 2 view
Tam Development Cellular diversity and lineage trajectory: insights from mouse single cell transcriptomes. 2020-01-24 10.1242/dev.179788 view
Durante Nat Commun Single-cell analysis reveals new evolutionary complexity in uveal melanoma. 2020-01-24 10.1038/s41467-019-14256-1 5 view
Wang Sci Rep Adaptive Landscape Shaped by Core Endogenous Network Coordinates Complex Early Progenitor Fate Commitments in Embryonic Pancreas. 2020-01-24 10.1038/s41598-020-57903-0 view
Ægidius Sci Rep Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis. 2020-01-24 10.1038/s41598-020-58059-7 1 view
Früh Vet. Immunol. Immunopathol. Elevated circulating Th2 but not group 2 innate lymphoid cell responses characterize canine atopic dermatitis. 2020-01-24 10.1016/j.vetimm.2020.110015 view
Weinreb Science Lineage tracing on transcriptional landscapes links state to fate during differentiation. 2020-01-23 10.1126/science.aaw3381 56 view
Ting Proc. Natl. Acad. Sci. U.S.A. A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease. 2020-01-23 10.1073/pnas.1914308117 1 view
Post Cell Snake Venom Gland Organoids. 2020-01-23 10.1016/j.cell.2019.11.038 view
Liu Genomics Single-cell alternative splicing analysis reveals dominance of single transcript variant. 2020-01-22 10.1016/j.ygeno.2020.01.014 view
Shnayder Elife Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state. 2020-01-22 10.7554/eLife.52168 1 view
Horns Cell Rep Memory B Cell Activation, Broad Anti-influenza Antibodies, and Bystander Activation Revealed by Single-Cell Transcriptomics. 2020-01-21 10.1016/j.celrep.2019.12.063 7 view
Czermiński Dev. Cell Silencing Trisomy 21 with XIST in Neural Stem Cells Promotes Neuronal Differentiation. 2020-01-21 10.1016/j.devcel.2019.12.015 view
Bangru Semin. Cell Dev. Biol. Cellular and molecular basis of liver regeneration. 2020-01-21 10.1016/j.semcdb.2019.12.004 2 view
Tan Development Single-cell RNAseq analysis of testicular germ and somatic cell development during the perinatal period. 2020-01-21 10.1242/dev.183251 view
Vigneron Proc. Natl. Acad. Sci. U.S.A. Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigens. 2020-01-21 10.1073/pnas.1914423117 view
Mashiko Sci Rep Chromosome segregation error during early cleavage in mouse pre-implantation embryo does not necessarily cause developmental failure after blastocyst stage. 2020-01-21 10.1038/s41598-020-57817-x view
Tsuyuzaki Genome Biol. Benchmarking principal component analysis for large-scale single-cell RNA-sequencing. 2020-01-20 10.1186/s13059-019-1900-3 2 view
Perlman Glia Developmental trajectory of oligodendrocyte progenitor cells in the human brain revealed by single cell RNA sequencing. 2020-01-20 10.1002/glia.23777 view
Kim Nat. Med. Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report. 2020-01-20 10.1038/s41591-019-0733-7 6 view
Pocha Clin. Cancer Res. Surfactant expression defines an inflamed subtype of lung adenocarcinoma brain metastases that correlates with prolonged survival. 2020-01-17 10.1158/1078-0432.CCR-19-2184 view
Yasen Infect. Genet. Evol. Progress and applications of single-cell sequencing techniques. 2020-01-17 10.1016/j.meegid.2020.104198 view
Jambusaria Elife Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation. 2020-01-16 10.7554/eLife.51413 view
Tran Genome Biol. A benchmark of batch-effect correction methods for single-cell RNA sequencing data. 2020-01-16 10.1186/s13059-019-1850-9 17 view
Matsushita Nat Commun A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration. 2020-01-16 10.1038/s41467-019-14029-w view
Soraggi Hum. Genet. Evaluating genetic causes of azoospermia: What can we learn from a complex cellular structure and single-cell transcriptomics of the human testis? 2020-01-16 10.1007/s00439-020-02116-8 3 view
Yang Stem Cell Reports Enhancing Hematopoiesis from Murine Embryonic Stem Cells through MLL1-Induced Activation of a Rac/Rho/Integrin Signaling Axis. 2020-01-16 10.1016/j.stemcr.2019.12.009 view
Zhu ACS Appl Mater Interfaces Dynamically Monitoring the Clonal Evolution of Lung Cancer Based on the Molecular Characterization of Circulating Tumor Cells using Aptamer Cocktail-Modified Nanosubstrates. 2020-01-15 10.1021/acsami.9b22234 view
Zhong Nature Decoding the development of the human hippocampus. 2020-01-15 10.1038/s41586-019-1917-5 view
Helmink Nature B cells and tertiary lymphoid structures promote immunotherapy response. 2020-01-15 10.1038/s41586-019-1922-8 view
Zhou Genome Biol. DENDRO: genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing. 2020-01-14 10.1186/s13059-019-1922-x view
Wang mBio Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection. 2020-01-14 10.1128/mBio.02880-19 view
Schafflick Nat Commun Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis. 2020-01-14 10.1038/s41467-019-14118-w view
Rubenstein Sci Rep Single-cell transcriptional profiles in human skeletal muscle. 2020-01-14 10.1038/s41598-019-57110-6 view
Svensson Nat. Biotechnol. Droplet scRNA-seq is not zero-inflated. 2020-01-14 10.1038/s41587-019-0379-5 view
Jost Nat. Biotechnol. Titrating gene expression using libraries of systematically attenuated CRISPR guide RNAs. 2020-01-13 10.1038/s41587-019-0387-5 view
Moncada Nat. Biotechnol. Integrating microarray-based spatial transcriptomics and single-cell RNA-seq reveals tissue architecture in pancreatic ductal adenocarcinomas. 2020-01-13 10.1038/s41587-019-0392-8 view
Ko Nat Protoc FLOW-MAP: a graph-based, force-directed layout algorithm for trajectory mapping in single-cell time course datasets. 2020-01-13 10.1038/s41596-019-0246-3 view
Goveia Cancer Cell An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates. 2020-01-13 10.1016/j.ccell.2019.12.001 1 view
Vorstandlechner FASEB J. Deciphering the functional heterogeneity of skin fibroblasts using single-cell RNA sequencing. 2020-01-12 10.1096/fj.201902001RR 1 view
Zaragosi Biochem. Soc. Trans. Using single-cell RNA sequencing to unravel cell lineage relationships in the respiratory tract. 2020-01-10 10.1042/BST20191010 view
Sheih Nat Commun Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy. 2020-01-10 10.1038/s41467-019-13880-1 view
Dong Brief. Bioinformatics SCDC: bulk gene expression deconvolution by multiple single-cell RNA sequencing references. 2020-01-10 10.1093/bib/bbz166 view
Nakagawa Curr. Hypertens. Rep. The Renin-Angiotensin System in the Central Nervous System and Its Role in Blood Pressure Regulation. 2020-01-10 10.1007/s11906-019-1011-2 view
Slaidina Genes Dev. A single-cell atlas of the developing Drosophila ovary identifies follicle stem cell progenitors. 2020-01-09 10.1101/gad.330464.119 2 view
Marouf Nat Commun Realistic in silico generation and augmentation of single-cell RNA-seq data using generative adversarial networks. 2020-01-09 10.1038/s41467-019-14018-z 9 view
Jarret Cell Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity. 2020-01-09 10.1016/j.cell.2019.12.016 5 view
Liu Blood Nivolumab treatment for relapsed/refractory Epstein-Barr virus-associated hemophagocytic lymphohistocytosis in adults. 2020-01-08 10.1182/blood.2019003886 1 view
Chen eNeuro Single-cell molecular and cellular architecture of the mouse neurohypophysis. 2020-01-08 10.1523/ENEURO.0345-19.2019 view
Hung Proc. Natl. Acad. Sci. U.S.A. A cell atlas of the adult Drosophila midgut. 2020-01-08 10.1073/pnas.1916820117 14 view
Gate Nature Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease. 2020-01-08 10.1038/s41586-019-1895-7 view
Diaz-Cuadros Nature In vitro characterization of the human segmentation clock. 2020-01-08 10.1038/s41586-019-1885-9 view
Han ACS Appl Mater Interfaces Photoactivated Selective Release of Droplets from Microwell Arrays. 2020-01-08 10.1021/acsami.9b17575 view
Li Elife Comprehensive transcriptome analysis of cochlear spiral ganglion neurons at multiple ages. 2020-01-08 10.7554/eLife.50491 view
Feng J Vis Exp Multiplexed Single Cell mRNA Sequencing Analysis of Mouse Embryonic Cells. 2020-01-07 10.3791/60647 view
Kupke Viruses Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. 2020-01-07 10.3390/v12010071 view
Faustino Martins Cell Stem Cell Self-Organizing 3D Human Trunk Neuromuscular Organoids. 2020-01-07 10.1016/j.stem.2019.12.007 view
Lederer Curr. Opin. Biotechnol. The emergence and promise of single-cell temporal-omics approaches. 2020-01-06 10.1016/j.copbio.2019.12.005 view
Rosado-Olivieri Cell Metab. Identification of a LIF-Responsive, Replication-Competent Subpopulation of Human β Cells. 2020-01-06 10.1016/j.cmet.2019.12.009 view
Bhattarai PLoS Biol. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain. 2020-01-06 10.1371/journal.pbio.3000585 view
Dou Nat. Biotechnol. Accurate detection of mosaic variants in sequencing data without matched controls. 2020-01-06 10.1038/s41587-019-0368-8 view
Yahara Nat. Cell Biol. Erythromyeloid progenitors give rise to a population of osteoclasts that contribute to bone homeostasis and repair. 2020-01-06 10.1038/s41556-019-0437-8 2 view
Motazedian Nat. Cell Biol. Multipotent RAG1+ progenitors emerge directly from haemogenic endothelium in human pluripotent stem cell-derived haematopoietic organoids. 2020-01-06 10.1038/s41556-019-0445-8 view
Pratapa Nat. Methods Benchmarking algorithms for gene regulatory network inference from single-cell transcriptomic data. 2020-01-06 10.1038/s41592-019-0690-6 view
Lange Development Single cell sequencing of radial glia progeny reveals diversity of newborn neurons in the adult zebrafish brain. 2020-01-06 10.1242/dev.185595 view
Serin Harmanci Nat Commun CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data. 2020-01-03 10.1038/s41467-019-13779-x view
Zhao Mucosal Immunol Single-cell RNA sequencing analysis reveals alginate oligosaccharides preventing chemotherapy-induced mucositis. 2020-01-03 10.1038/s41385-019-0248-z view
Delacher Immunity Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF. 2020-01-02 10.1016/j.immuni.2019.12.002 6 view
Liao Sci Data Single-cell RNA sequencing of human kidney. 2020-01-02 10.1038/s41597-019-0351-8 9 view
Bhaduri Cell Stem Cell Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. 2020-01-02 10.1016/j.stem.2019.11.015 view
Redick FASEB J. Recovery of viable endocrine-specific cells and transcriptomes from human pancreatic islet-engrafted mice. 2020-01-01 10.1096/fj.201901022RR view
Kong FASEB J. Lineage specification and pluripotency revealed by transcriptome analysis from oocyte to blastocyst in pig. 2020-01-01 10.1096/fj.201901818RR view
Hollenhorst FASEB J. Tracheal brush cells release acetylcholine in response to bitter tastants for paracrine and autocrine signaling. 2020-01-01 10.1096/fj.201901314RR 3 view
Zhou Adv Sci (Weinh) Chemical Cocktail Induces Hematopoietic Reprogramming and Expands Hematopoietic Stem/Progenitor Cells. 2020-01-01 10.1002/advs.201901785 view
Ubags ERJ Open Res ERS International Congress, Madrid, 2019: highlights from the Basic and Translational Science Assembly. 2020-01-01 10.1183/23120541.00350-2019 view
Vijay Nat Metab Single-cell analysis of human adipose tissue identifies depot and disease specific cell types. 2020-01-01 10.1038/s42255-019-0152-6 1 view
Bonnycastle Biol Methods Protoc Single-cell transcriptomics from human pancreatic islets: sample preparation matters. 2020-01-01 10.1093/biomethods/bpz019 view
Filippo Methods Mol. Biol. Single-cell Digital Twins for Cancer Preclinical Investigation. 2020-01-01 10.1007/978-1-0716-0159-4_15 view
Luo Methods Mol. Biol. Simultaneous Measurement of Surface Proteins and Gene Expression from Single Cells. 2020-01-01 10.1007/978-1-0716-0266-9_3 view
Ferguson Methods Mol. Biol. Analysis of Transcriptional Profiling of Immune Cells at the Single-Cell Level. 2020-01-01 10.1007/978-1-0716-0266-9_4 3 view
Goldberg Nat Metab Ketogenesis activates metabolically protective γδ T cells in visceral adipose tissue. 2020-01-01 10.1038/s42255-019-0160-6 6 view
Plemel Sci Adv Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion. 2020-01-01 10.1126/sciadv.aay6324 7 view
González-Silva Trends Cancer Tumor Functional Heterogeneity Unraveled by scRNA-seq Technologies. 2020-01-01 10.1016/j.trecan.2019.11.010 4 view
Bykov Meth. Enzymol. Preparation of single cells from tumors for single-cell RNA sequencing. 2020-01-01 10.1016/bs.mie.2019.05.057 view
Araya Meth. Enzymol. Characterization of the tumor immune infiltrate by multiparametric flow cytometry and unbiased high-dimensional data analysis. 2020-01-01 10.1016/bs.mie.2019.11.012 1 view
Alessio Int J Mol Sci A Single Cell but Many Different Transcripts: A Journey into the World of Long Non-Coding RNAs. 2020-01-01 10.3390/ijms21010302 view
Geoghegan MethodsX Method for RNA extraction and transcriptomic analysis of single fungal spores. 2020-01-01 10.1016/j.mex.2019.12.002 view
Zhu Curr. Genomics Novel Approaches to Profile Functional Long Noncoding RNAs Associated with Stem Cell Pluripotency. 2020-01-01 10.2174/1389202921666200210142840 view
Zhou Methods Mol. Biol. Visualization of Single Cell RNA-Seq Data Using t-SNE in R. 2020-01-01 10.1007/978-1-0716-0301-7_8 view
Zhong Methods Mol. Biol. Use of SuperCT for Enhanced Characterization of Single-Cell Transcriptomic Profiles. 2020-01-01 10.1007/978-1-0716-0301-7_9 view
Madissoon Genome Biol. scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation. 2019-12-31 10.1186/s13059-019-1906-x 4 view
Yang BMC Genomics Cloud accelerated alignment and assembly of full-length single-cell RNA-seq data using Falco. 2019-12-30 10.1186/s12864-019-6341-6 view
Mieth Sci Rep Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data. 2019-12-30 10.1038/s41598-019-56911-z view
Liu J. Int. Med. Res. Identification of key genes and pathways in abdominal aortic aneurysm by integrated bioinformatics analysis. 2019-12-29 10.1177/0300060519894437 view
Luo Nephrol. Dial. Transplant. A single-cell map for the transcriptomic signatures of peripheral blood mononuclear cells in end-stage renal disease. 2019-12-28 10.1093/ndt/gfz227 1 view
Du Eur. J. Paediatr. Neurol. Differential excitatory vs inhibitory SCN expression at single cell level regulates brain sodium channel function in neurodevelopmental disorders. 2019-12-28 10.1016/j.ejpn.2019.12.019 view
Yuan Breast Cancer Res. S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis. 2019-12-27 10.1186/s13058-019-1238-5 view
Brierley Curr Opin Oncol Single-cell sequencing in hematology. 2019-12-27 10.1097/CCO.0000000000000613 view
Wang BMC Genomics Exploring the changing landscape of cell-to-cell variation after CTCF knockdown via single cell RNA-seq. 2019-12-26 10.1186/s12864-019-6379-5 view
Tang Cell Stem Cell Arterial Sca1+ Vascular Stem Cells Generate De Novo Smooth Muscle for Artery Repair and Regeneration. 2019-12-26 10.1016/j.stem.2019.11.010 view
Hoof J. Allergy Clin. Immunol. Allergen-specific IgG+ memory B cells are temporally linked to IgE memory responses. 2019-12-26 10.1016/j.jaci.2019.11.046 view
Lee Cytokine Bulk and single cell transcriptomic data indicate that a dichotomy between inflammatory pathways in peripheral blood and arthritic joints complicates biomarker discovery. 2019-12-24 10.1016/j.cyto.2019.154960 1 view
Geddes BMC Bioinformatics Autoencoder-based cluster ensembles for single-cell RNA-seq data analysis. 2019-12-24 10.1186/s12859-019-3179-5 view
Cao BMC Bioinformatics scDC: single cell differential composition analysis. 2019-12-24 10.1186/s12859-019-3211-9 view
Kim BMC Genomics scReClassify: post hoc cell type classification of single-cell rNA-seq data. 2019-12-24 10.1186/s12864-019-6305-x view
Yan MBio Single-Cell Transcriptomics Reveal a Correlation between Genome Architecture and Gene Family Evolution in Ciliates. 2019-12-24 10.1128/mBio.02524-19 view
Chen Cell Rep Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. 2019-12-24 10.1016/j.celrep.2019.11.083 2 view
Honkoop Elife Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart. 2019-12-23 10.7554/eLife.50163 view
Townes Genome Biol. Feature selection and dimension reduction for single-cell RNA-Seq based on a multinomial model. 2019-12-23 10.1186/s13059-019-1861-6 21 view
Hafemeister Genome Biol. Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression. 2019-12-23 10.1186/s13059-019-1874-1 61 view
Perez-Rodriguez Acta Neuropathol Commun Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing. 2019-12-23 10.1186/s40478-019-0873-5 1 view
Sun Ann. Rheum. Dis. Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration. 2019-12-23 10.1136/annrheumdis-2019-215926 view
Haftbaradaran Esfahani Basic Res. Cardiol. Cell shape determines gene expression: cardiomyocyte morphotypic transcriptomes. 2019-12-23 10.1007/s00395-019-0765-7 view
Gehring Nat. Biotechnol. Highly multiplexed single-cell RNA-seq by DNA oligonucleotide tagging of cellular proteins. 2019-12-23 10.1038/s41587-019-0372-z 6 view
Goswami Nat. Med. Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma. 2019-12-23 10.1038/s41591-019-0694-x 7 view
Chen Stem Cell Res Ther Menstrual blood-derived stem cells: toward therapeutic mechanisms, novel strategies, and future perspectives in the treatment of diseases. 2019-12-21 10.1186/s13287-019-1503-7 3 view
Kelly Matrix Biol. Single cell RNA-sequencing reveals cellular heterogeneity and trajectories of lineage specification during murine embryonic limb development. 2019-12-21 10.1016/j.matbio.2019.12.004 view
Zhang BMC Bioinformatics M3S: a comprehensive model selection for multi-modal single-cell RNA sequencing data. 2019-12-20 10.1186/s12859-019-3243-1 1 view
Ocasio Nat Commun scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy. 2019-12-20 10.1038/s41467-019-13657-6 view
Liu Theriogenology Inhibition of lysine-specific histone demethylase 1A results in meiotic aberration during oocyte maturation in vitro in goats. 2019-12-19 10.1016/j.theriogenology.2019.12.011 view
Walzer PLoS Genet. Latent transcriptional variations of individual Plasmodium falciparum uncovered by single-cell RNA-seq and fluorescence imaging. 2019-12-19 10.1371/journal.pgen.1008506 2 view
Xu Genome Biol. Genotype-free demultiplexing of pooled single-cell RNA-seq. 2019-12-19 10.1186/s13059-019-1852-7 6 view
Aoki Cancer Discov Single cell transcriptome analysis reveals disease-defining T cell subsets in the tumor microenvironment of classic Hodgkin lymphoma. 2019-12-19 10.1158/2159-8290.CD-19-0680 3 view
Osorio Cells Single-Cell Expression Variability Implies Cell Function. 2019-12-19 10.3390/cells9010014 view
Nguyen Sci Transl Med Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells. 2019-12-18 10.1126/scitranslmed.aax4077 view
Rao Nat Rev Nephrol Design and application of single-cell RNA sequencing to study kidney immune cells in lupus nephritis. 2019-12-18 10.1038/s41581-019-0232-6 1 view
Jia J. Cell. Mol. Med. Identification of differentially expressed genes by single-cell transcriptional profiling of umbilical cord and synovial fluid mesenchymal stem cells. 2019-12-17 10.1111/jcmm.14891 view
Feng Bioinformatics scTIM: Seeking Cell-Type-Indicative Marker from single cell RNA-seq data by consensus optimization. 2019-12-17 10.1093/bioinformatics/btz936 view
Gerrits Glia Transcriptional profiling of microglia; current state of the art and future perspectives. 2019-12-17 10.1002/glia.23767 view
Liang Nat Commun Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling. 2019-12-17 10.1038/s41467-019-12917-9 5 view
Melcher Acta Neuropathol. Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance. 2019-12-17 10.1007/s00401-019-02116-7 2 view
Fukushima Cell Rep Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium. 2019-12-17 10.1016/j.celrep.2019.11.061 view
Guo Cell Rep The Cellular Diversity and Transcription Factor Code of Drosophila Enteroendocrine Cells. 2019-12-17 10.1016/j.celrep.2019.11.048 1 view
Bajpai J Vis Exp Isolation of Macrophage Subsets and Stromal Cells from Human and Mouse Myocardial Specimens. 2019-12-17 10.3791/60015 view
Heng Proc. Natl. Acad. Sci. U.S.A. Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing. 2019-12-16 10.1073/pnas.1915571116 view
van Es Proc. Natl. Acad. Sci. U.S.A. Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion. 2019-12-16 10.1073/pnas.1801888117 view
Wünnemann Nat. Genet. Loss of ADAMTS19 causes progressive non-syndromic heart valve disease. 2019-12-16 10.1038/s41588-019-0536-2 3 view
Pang Cancers (Basel) Discovering Rare Genes Contributing to Cancer Stemness and Invasive Potential by GBM Single-Cell Transcriptional Analysis. 2019-12-16 10.3390/cancers11122025 view
Diaz-Hernandez J. Cell. Physiol. Derivation of notochordal cells from human embryonic stem cells reveals unique regulatory networks by single cell-transcriptomics. 2019-12-16 10.1002/jcp.29411 3 view
Torii Plant Cell Physiol. Time-series single-cell RNA-seq data reveal auxin fluctuation during endocycle. 2019-12-16 10.1093/pcp/pcz228 view
Andrianova Int J Mol Sci Kidney Cells Regeneration: Dedifferentiation of Tubular Epithelium, Resident Stem Cells and Possible Niches for Renal Progenitors. 2019-12-15 10.3390/ijms20246326 view
Gambardella Development BNC1 regulates cell heterogeneity in human pluripotent stem cell-derived epicardium. 2019-12-13 10.1242/dev.174441 view
Huang Genome Biol. Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference. 2019-12-13 10.1186/s13059-019-1865-2 5 view
Halaby Sci Immunol GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment. 2019-12-13 10.1126/sciimmunol.aax8189 2 view
Barry Nat Commun Molecular determinants of nephron vascular specialization in the kidney. 2019-12-13 10.1038/s41467-019-12872-5 1 view
Alquicira-Hernandez Genome Biol. scPred: accurate supervised method for cell-type classification from single-cell RNA-seq data. 2019-12-12 10.1186/s13059-019-1862-5 view
Pique-Regi Elife Single cell transcriptional signatures of the human placenta in term and preterm parturition. 2019-12-12 10.7554/eLife.52004 view
Li Clin. Cancer Res. Investigation of antigen-specific T cell receptor clusters in human cancers. 2019-12-12 10.1158/1078-0432.CCR-19-3249 view
Stewart Nat Rev Nephrol Using single-cell technologies to map the human immune system - implications for nephrology. 2019-12-12 10.1038/s41581-019-0227-3 1 view
Asp Cell A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart. 2019-12-12 10.1016/j.cell.2019.11.025 5 view
Corley Sci Rep QuantSeq. 3' Sequencing combined with Salmon provides a fast, reliable approach for high throughput RNA expression analysis. 2019-12-11 10.1038/s41598-019-55434-x view
Taguchi Curr. Pharm. Des. Neurological disorder drug discovery from gene expression with tensor decomposition. 2019-12-10 10.2174/1381612825666191210160906 view
Sun Genome Biol. Accuracy, robustness and scalability of dimensionality reduction methods for single-cell RNA-seq analysis. 2019-12-10 10.1186/s13059-019-1898-6 view
Dumas J. Am. Soc. Nephrol. Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation. 2019-12-09 10.1681/ASN.2019080832 6 view
de Andrade JCI Insight Discovery of specialized NK cell populations infiltrating human melanoma metastases. 2019-12-05 10.1172/jci.insight.133103 view
Ryan Wiley Interdiscip Rev Syst Biol Med Functional genomic approaches to elucidate the role of enhancers during development. 2019-12-05 10.1002/wsbm.1467 view
Scott Cell Stem Cell Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration. 2019-12-05 10.1016/j.stem.2019.11.004 view
Stanley Neuron Continuous and Discrete Neuron Types of the Adult Murine Striatum. 2019-12-05 10.1016/j.neuron.2019.11.004 6 view
Sun Nucleic Acids Res. Allele-specific single-cell RNA sequencing reveals different architectures of intrinsic and extrinsic gene expression noises. 2019-12-04 10.1093/nar/gkz1134 2 view
Xu J. Leukoc. Biol. Dissecting the human immune system with single cell RNA sequencing technology. 2019-12-04 10.1002/JLB.5MR1019-179R 1 view
Freytag Bioinformatics schex avoids overplotting for large single cell RNA-sequencing datasets. 2019-12-03 10.1093/bioinformatics/btz907 view
Zerti Curr. Eye Res. Understanding the complexity of retina and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospective. 2019-12-03 10.1080/02713683.2019.1697453 1 view
Fouillade Clin. Cancer Res. FLASH irradiation spares lung progenitor cells and limits the incidence of radio-induced senescence. 2019-12-03 10.1158/1078-0432.CCR-19-1440 2 view
Li Cell Rep IL-33 Signaling Alters Regulatory T Cell Diversity in Support of Tumor Development. 2019-12-03 10.1016/j.celrep.2019.10.120 2 view
Zhou J Vis Exp Isolation of Region-specific Microglia from One Adult Mouse Brain Hemisphere for Deep Single-cell RNA Sequencing. 2019-12-03 10.3791/60347 view
Kang PLoS Comput. Biol. CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data. 2019-12-02 10.1371/journal.pcbi.1007510 1 view
La Manno Nat. Biotechnol. From single-cell RNA-seq to transcriptional regulation. 2019-12-02 10.1038/s41587-019-0327-4 view
Ngo Trong J. Comput. Biol. Semisupervised Generative Autoencoder for Single-Cell Data. 2019-12-02 10.1089/cmb.2019.0337 view
Todorov Methods Mol. Biol. Network Inference from Single-Cell Transcriptomic Data. 2019-12-01 10.1007/978-1-4939-8882-2_10 11 view
Sivakumar Curr Stem Cell Rep Paradigms that define lung epithelial progenitor cell fate in development and regeneration. 2019-12-01 10.1007/s40778-019-00166-x view
Yu Adv. Exp. Med. Biol. Identification of a Unique Subretinal Microglia Type in Retinal Degeneration Using Single Cell RNA-Seq. 2019-12-01 10.1007/978-3-030-27378-1_30 view
Duclos Sci Adv Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. 2019-12-01 10.1126/sciadv.aaw3413 5 view
Deng Aging Dis AmpliSeq Transcriptome of Laser Captured Neurons from Alzheimer Brain: Comparison of Single Cell Versus Neuron Pools. 2019-12-01 10.14336/AD.2019.0225 view
Tu Nat. Immunol. TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures. 2019-12-01 10.1038/s41590-019-0544-5 view
Hu PLoS ONE HeLa-CCL2 cell heterogeneity studied by single-cell DNA and RNA sequencing. 2019-12-01 10.1371/journal.pone.0225466 view
Elmentaite Curr Opin Syst Biol Studying immune to non-immune cell cross-talk using single-cell technologies. 2019-12-01 10.1016/j.coisb.2019.10.005 view
Qi Front Genet Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System. 2019-12-01 10.3389/fgene.2019.01202 view
Moon Nat. Biotechnol. Visualizing structure and transitions in high-dimensional biological data. 2019-12-01 10.1038/s41587-019-0336-3 54 view
Hayward Front Cell Infect Microbiol Early Transcriptional Landscapes of Chlamydia trachomatis-Infected Epithelial Cells at Single Cell Resolution. 2019-12-01 10.3389/fcimb.2019.00392 view
Liu Cancers (Basel) Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer. 2019-12-01 10.3390/cancers11121910 1 view
Zhang Anim Cells Syst (Seoul) Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus. 2019-12-01 10.1080/19768354.2019.1696406 view
Kang Ann Transl Med The application of single-cell sequencing technology in the diagnosis and treatment of hepatocellular carcinoma. 2019-12-01 10.21037/atm.2019.11.116 view
Bakhti Mol Metab Establishment of a high-resolution 3D modeling system for studying pancreatic epithelial cell biology in vitro. 2019-12-01 10.1016/j.molmet.2019.09.005 2 view
Cho Life Sci Alliance Refining the adipose progenitor cell landscape in healthy and obese visceral adipose tissue using single-cell gene expression profiling. 2019-12-01 10.26508/lsa.201900561 view
Li Onco Targets Ther Siglecs, Novel Immunotherapy Targets, Potentially Enhance The Effectiveness of Existing Immune Checkpoint Inhibitors in Glioma Immunotherapy. 2019-12-01 10.2147/OTT.S223406 view
Espinosa-Medina Open Biol High-throughput dense reconstruction of cell lineages. 2019-12-01 10.1098/rsob.190229 1 view
Etherington Gigascience A Galaxy-based training resource for single-cell RNA-sequencing quality control and analyses. 2019-12-01 10.1093/gigascience/giz144 view
Guthmiller Methods Mol. Biol. An Efficient Method to Generate Monoclonal Antibodies from Human B Cells. 2019-12-01 10.1007/978-1-4939-8958-4_5 1 view
Ismail Quant Biol Algorithmic approaches to clonal reconstruction in heterogeneous cell populations. 2019-12-01 10.1007/s40484-019-0188-3 view
Agarwal Sci Adv Semblance: An empirical similarity kernel on probability spaces. 2019-12-01 10.1126/sciadv.aau9630 1 view
Raredon Sci Adv Single-cell connectomic analysis of adult mammalian lungs. 2019-12-01 10.1126/sciadv.aaw3851 8 view
Close Clin. Exp. Immunol. Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma. 2019-11-30 10.1111/cei.13403 3 view
Sachs Cancer Res. Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia. 2019-11-29 10.1158/0008-5472.CAN-18-2932 view
Subramanian Nat Commun Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation. 2019-11-29 10.1038/s41467-019-13382-0 5 view
Xue J. Dermatol. Sci. Transcriptome landscape of myeloid cells in human skin reveals diversity, rare populations and putative DC progenitors. 2019-11-29 10.1016/j.jdermsci.2019.11.012 view
Nam Exp. Mol. Med. Graft immaturity and safety concerns in transplanted human kidney organoids. 2019-11-28 10.1038/s12276-019-0336-x 1 view
Huh Nucleic Acids Res. SAME-clustering: Single-cell Aggregated Clustering via Mixture Model Ensemble. 2019-11-28 10.1093/nar/gkz959 view
Su Bioinformatics CellBench: R/Bioconductor software for comparing single-cell RNA-seq analysis methods. 2019-11-28 10.1093/bioinformatics/btz889 4 view
Kobak Nat Commun The art of using t-SNE for single-cell transcriptomics. 2019-11-28 10.1038/s41467-019-13056-x view
Zander Immunity CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. 2019-11-27 10.1016/j.immuni.2019.10.009 view
Pan J Hematol Oncol Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer. 2019-11-27 10.1186/s13045-019-0822-6 view
Turco Development Development of the human placenta. 2019-11-27 10.1242/dev.163428 6 view
Farnsworth Dev. Biol. A single-cell transcriptome atlas for zebrafish development. 2019-11-26 10.1016/j.ydbio.2019.11.008 view
Svoboda Proc. Natl. Acad. Sci. U.S.A. Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain. 2019-11-26 10.1073/pnas.1913541116 11 view
Nagata Nat Commun Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes. 2019-11-26 10.1038/s41467-019-13001-y view
Kang Mucosal Immunol Commensal microbiota drive the functional diversification of colon macrophages. 2019-11-26 10.1038/s41385-019-0228-3 view
Pauly Cell Rep Cell-Type-Specific Complement Expression in the Healthy and Diseased Retina. 2019-11-26 10.1016/j.celrep.2019.10.084 view
Lam J. Clin. Invest. Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis. 2019-11-25 10.1172/JCI129833 2 view
Vickman Prostate Heterogeneity of human prostate carcinoma-associated fibroblasts implicates a role for subpopulations in myeloid cell recruitment. 2019-11-25 10.1002/pros.23929 view
Amses Bioinformatics SCGid, a consensus approach to contig filtering and genome prediction from single cell sequencing libraries of uncultured eukaryotes. 2019-11-25 10.1093/bioinformatics/btz866 view
Hillje Bioinformatics Cerebro: Interactive visualization of scRNA-seq data. 2019-11-25 10.1093/bioinformatics/btz877 3 view
Harvey Nat. Cell Biol. A Tppp3+Pdgfra+ tendon stem cell population contributes to regeneration and reveals a shared role for PDGF signalling in regeneration and fibrosis. 2019-11-25 10.1038/s41556-019-0417-z view
Ku Philos. Trans. R. Soc. Lond., B, Biol. Sci. Using single-cell transcriptomics to understand functional states and interactions in microbial eukaryotes. 2019-11-25 10.1098/rstb.2019.0098 1 view
Florenza Philos. Trans. R. Soc. Lond., B, Biol. Sci. Uncovering microbial inter-domain interactions in complex communities. 2019-11-25 10.1098/rstb.2019.0087 2 view
Rich-Griffin Trends Plant Sci. Single-Cell Transcriptomics: A High-Resolution Avenue for Plant Functional Genomics. 2019-11-25 10.1016/j.tplants.2019.10.008 2 view
Ansaloni BMC Bioinformatics Exploratory analysis of transposable elements expression in the C. elegans early embryo. 2019-11-22 10.1186/s12859-019-3088-7 view
Koay Sci Immunol A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. 2019-11-22 10.1126/sciimmunol.aay6039 view
Jang Radiother Oncol Tumor mutation burden, immune checkpoint crosstalk and radiosensitivity in single-cell RNA sequencing data of breast cancer. 2019-11-22 10.1016/j.radonc.2019.11.003 view
Hilton PLoS Biol. Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity. 2019-11-21 10.1371/journal.pbio.3000528 view
Wang J. Exp. Med. Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine. 2019-11-21 10.1084/jem.20191130 2 view
Kimmel Genome Res. Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging. 2019-11-21 10.1101/gr.253880.119 view
Mistry Proc. Natl. Acad. Sci. U.S.A. Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus. 2019-11-21 10.1073/pnas.1908576116 view
Guan J. Hepatol. The Phosphatidylethanolamine Biosynthesis Pathway Provides a New Target for Cancer Chemotherapy. 2019-11-21 10.1016/j.jhep.2019.11.007 3 view
Tran Neuron Single-Cell Profiles of Retinal Ganglion Cells Differing in Resilience to Injury Reveal Neuroprotective Genes. 2019-11-20 10.1016/j.neuron.2019.11.006 view
Zhang Aging (Albany NY) Development and validation of a metastasis-associated prognostic signature based on single-cell RNA-seq in clear cell renal cell carcinoma. 2019-11-20 10.18632/aging.102434 view
Thompson Nature Genetic predisposition to mosaic Y chromosome loss in blood. 2019-11-20 10.1038/s41586-019-1765-3 view
Liu Genome Biol. Systematic comparative analysis of single-nucleotide variant detection methods from single-cell RNA sequencing data. 2019-11-19 10.1186/s13059-019-1863-4 view
Li Gut Genomic and transcriptomic profiling of carcinogenesis in patients with familial adenomatous polyposis. 2019-11-19 10.1136/gutjnl-2019-319438 view
Ellender Nat Commun Embryonic progenitor pools generate diversity in fine-scale excitatory cortical subnetworks. 2019-11-19 10.1038/s41467-019-13206-1 1 view
Fowler Wiley Interdiscip Rev Dev Biol A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids. 2019-11-19 10.1002/wdev.368 1 view
Zhou Immunity Building a Human Thymus: A Pointillist View. 2019-11-19 10.1016/j.immuni.2019.10.003 view
Sharma Cell Rep Non-Genetic Intra-Tumor Heterogeneity Is a Major Predictor of Phenotypic Heterogeneity and Ongoing Evolutionary Dynamics in Lung Tumors. 2019-11-19 10.1016/j.celrep.2019.10.045 view
Zhang IEEE Trans Cybern Nature-Inspired Compressed Sensing for Transcriptomic Profiling From Random Composite Measurements. 2019-11-19 10.1109/TCYB.2019.2951402 view
N Holding Biochim Biophys Acta Gene Regul Mech Data generation and network reconstruction strategies for single cell transcriptomic profiles of CRISPR-mediated gene perturbations. 2019-11-19 10.1016/j.bbagrm.2019.194441 view
Singh Cell Mol Gastroenterol Hepatol Enteroendocrine progenitor cell enriched miR-7 regulates intestinal epithelial proliferation in an Xiap-dependent manner. 2019-11-19 10.1016/j.jcmgh.2019.11.001 view
Winkler J Neuroinflammation Neuronal maturation reduces the type I IFN response to orthobunyavirus infection and leads to increased apoptosis of human neurons. 2019-11-18 10.1186/s12974-019-1614-1 1 view
Chen Genome Biol. Assessment of computational methods for the analysis of single-cell ATAC-seq data. 2019-11-18 10.1186/s13059-019-1854-5 view
Zhao Development Single cell transcriptome dynamics from pluripotency to FLK1+ mesoderm. 2019-11-18 10.1242/dev.182097 view
Sankowski Nat. Neurosci. Mapping microglia states in the human brain through the integration of high-dimensional techniques. 2019-11-18 10.1038/s41593-019-0532-y view
Qian Nat. Methods Probabilistic cell typing enables fine mapping of closely related cell types in situ. 2019-11-18 10.1038/s41592-019-0631-4 25 view
Korsunsky Nat. Methods Fast, sensitive and accurate integration of single-cell data with Harmony. 2019-11-18 10.1038/s41592-019-0619-0 18 view
Kyrochristos Cancers (Basel) Bulk and Single-Cell Next-Generation Sequencing: Individualizing Treatment for Colorectal Cancer. 2019-11-18 10.3390/cancers11111809 view
Bolander Stem Cells Transl Med Single-cell characterization and metabolic profiling of in vitro cultured human skeletal progenitors with enhanced in vivo bone forming capacity. 2019-11-18 10.1002/sctm.19-0151 view
Gille Int J Mol Sci Contribution of Single-Cell Transcriptomics to the Characterization of Human Spermatogonial Stem Cells: Toward an Application in Male Fertility Regenerative Medicine? 2019-11-16 10.3390/ijms20225773 view
Wang Nat Commun Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice. 2019-11-15 10.1038/s41467-019-13193-3 view
Choi Nat Commun A Bayesian mixture model for the analysis of allelic expression in single cells. 2019-11-15 10.1038/s41467-019-13099-0 view
Eggesbø Mucosal Immunol Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease. 2019-11-14 10.1038/s41385-019-0222-9 3 view
Bai Cell Genetic Identification of Vagal Sensory Neurons That Control Feeding. 2019-11-14 10.1016/j.cell.2019.10.031 29 view
Hollern Cell B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer. 2019-11-14 10.1016/j.cell.2019.10.028 3 view
Shi PLoS Comput. Biol. Quantifying pluripotency landscape of cell differentiation from scRNA-seq data by continuous birth-death process. 2019-11-13 10.1371/journal.pcbi.1007488 1 view
Ruan BMC Biol. Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment. 2019-11-13 10.1186/s12915-019-0709-6 3 view
Zou J. Pineal Res. Melatonin promotes the development of immature oocytes from the COH cycle into healthy offspring by protecting mitochondrial function. 2019-11-12 10.1111/jpi.12621 view
Evren Immunology Origin and Ontogeny of Lung Macrophages: From Mice to Humans. 2019-11-12 10.1111/imm.13154 1 view
Davis BMC Bioinformatics SCOPIT: sample size calculations for single-cell sequencing experiments. 2019-11-12 10.1186/s12859-019-3167-9 6 view
Liu BMC Immunol. Subsets of mononuclear phagocytes are enriched in the inflamed colons of patients with IBD. 2019-11-12 10.1186/s12865-019-0322-z view
Hashimoto Proc. Natl. Acad. Sci. U.S.A. Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians. 2019-11-12 10.1073/pnas.1907883116 view
Dobie Cell Rep Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis. 2019-11-12 10.1016/j.celrep.2019.10.024 29 view
Smith Elife Single-cell transcriptomic evidence for dense intracortical neuropeptide networks. 2019-11-11 10.7554/eLife.47889 1 view
Chen Analyst Single-cell RNA-sequencing of migratory breast cancer cells: discovering genes associated with cancer metastasis. 2019-11-11 10.1039/c9an01358j 3 view
Co Cereb. Cortex Cortical Foxp2 Supports Behavioral Flexibility and Developmental Dopamine D1 Receptor Expression. 2019-11-11 10.1093/cercor/bhz209 1 view
Voigt Proc. Natl. Acad. Sci. U.S.A. Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration. 2019-11-11 10.1073/pnas.1914143116 3 view
Cleuren Proc. Natl. Acad. Sci. U.S.A. The in vivo endothelial cell translatome is highly heterogeneous across vascular beds. 2019-11-11 10.1073/pnas.1912409116 4 view
Hummel Mucosal Immunol Single-cell RNA-sequencing identifies the developmental trajectory of C-Myc-dependent NK1.1- T-bet+ intraepithelial lymphocyte precursors. 2019-11-11 10.1038/s41385-019-0220-y view
Wang Nucleic Acids Res. CancerTracer: a curated database for intrapatient tumor heterogeneity. 2019-11-08 10.1093/nar/gkz1061 1 view
Lourenco Cancer Res. Differential contributions of pre- and post- EMT tumor cells in breast cancer metastasis. 2019-11-08 10.1158/0008-5472.CAN-19-1427 view
Oota Methods Somatic mutations ---Evolution within the individual. 2019-11-08 10.1016/j.ymeth.2019.11.002 view
Ravichandran Bioinformatics SigHotSpotter: scRNA-seq-based computational tool to control cell subpopulation phenotypes for cellular rejuvenation strategies. 2019-11-07 10.1093/bioinformatics/btz827 view
Cai Bioinformatics scGEAToolbox: a Matlab toolbox for single-cell RNA sequencing data analysis. 2019-11-07 10.1093/bioinformatics/btz830 1 view
Zucha Clin. Chem. Performance Comparison of Reverse Transcriptases for Single-Cell Studies. 2019-11-07 10.1373/clinchem.2019.307835 view
Dominguez Cancer Discov Single-cell RNA sequencing reveals stromal evolution into LRRC15+ myofibroblasts as a determinant of patient response to cancer immunotherapy. 2019-11-07 10.1158/2159-8290.CD-19-0644 view
Zhang J. Biol. Chem. Photic generation of 11-cis-retinal in bovine retinal pigment epithelium. 2019-11-06 10.1074/jbc.RA119.011169 view
Sinha Bioinformatics Improved dropClust R package with integrative analysis support for scRNA-seq data. 2019-11-06 10.1093/bioinformatics/btz823 view
DePasquale Cell Rep DoubletDecon: Deconvoluting Doublets from Single-Cell RNA-Sequencing Data. 2019-11-05 10.1016/j.celrep.2019.09.082 view
Kurmangaliyev Elife Modular transcriptional programs separately define axon and dendrite connectivity. 2019-11-05 10.7554/eLife.50822 4 view
Zhang Analyst Improving single-cell transcriptome sequencing efficiency with a microfluidic phase-switch device. 2019-11-05 10.1039/c9an00823c view
Bourillot Exp. Cell Res. GP130 signaling and the control of naïve pluripotency in humans, monkeys, and pigs. 2019-11-04 10.1016/j.yexcr.2019.111712 view
Jansen PLoS Comput. Biol. Building gene regulatory networks from scATAC-seq and scRNA-seq using Linked Self Organizing Maps. 2019-11-04 10.1371/journal.pcbi.1006555 view
Pratama J. Exp. Med. Developmental and cellular age direct conversion of CD4+ T cells into RORγ+ or Helios+ colon Treg cells. 2019-11-04 10.1084/jem.20190428 view
Xu Cancer Immunol. Immunother. Preclinical development of T-cell receptor-engineered T-cell therapy targeting the 5T4 tumor antigen on renal cell carcinoma. 2019-11-04 10.1007/s00262-019-02419-4 2 view
Ransick Dev. Cell Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. 2019-11-04 10.1016/j.devcel.2019.10.005 view
He J. Cell. Biochem. Differential expression of α6 and β1 integrins reveals epidermal heterogeneity at single-cell resolution. 2019-11-03 10.1002/jcb.29487 view
Qi Oral Oncol. Single-cell sequencing and its applications in head and neck cancer. 2019-11-02 10.1016/j.oraloncology.2019.104441 view
Ren Adv. Immunol. Understanding tumor-infiltrating lymphocytes by single cell RNA sequencing. 2019-11-01 10.1016/ view
Kanaya Commun Biol Single-cell RNA-sequencing analysis of estrogen- and endocrine-disrupting chemical-induced reorganization of mouse mammary gland. 2019-11-01 10.1038/s42003-019-0618-9 view
Wen J. Allergy Clin. Immunol. Cell-by-cell deciphering of T cells in allergic inflammation. 2019-11-01 10.1016/j.jaci.2019.10.001 view
Lee Nat Metab IDOL regulates systemic energy balance through control of neuronal VLDLR expression. 2019-11-01 10.1038/s42255-019-0127-7 view
Torroja Front Genet Digitaldlsorter: Deep-Learning on scRNA-Seq to Deconvolute Gene Expression Data. 2019-11-01 10.3389/fgene.2019.00978 view
Hayashi Adv. Exp. Med. Biol. Heterogeneity of Oligodendrocytes and Their Precursor Cells. 2019-11-01 10.1007/978-981-32-9636-7_5 view
Deaton Adv Biosyst Mini-Metagenomics and Nucleotide Composition Aid the Identification and Host Association of Novel Bacteriophage Sequences. 2019-11-01 10.1002/adbi.201900108 view
Billing Mol Metab Single cell transcriptomic profiling of large intestinal enteroendocrine cells in mice - Identification of selective stimuli for insulin-like peptide-5 and glucagon-like peptide-1 co-expressing cells. 2019-11-01 10.1016/j.molmet.2019.09.001 view
Wilson Hemasphere Single-Cell Sequencing in Normal and Malignant Hematopoiesis. 2019-11-01 10.1097/HS9.0000000000000034 7 view
Pallares G3 (Bethesda) TM3'seq: A Tagmentation-Mediated 3' Sequencing Approach for Improving Scalability of RNAseq Experiments. 2019-11-01 10.1534/g3.119.400821 view
Borrell F1000Res Recent advances in understanding neocortical development. 2019-11-01 10.12688/f1000research.20332.1 view
Barkley Trends Cancer Plasticity and Clonality of Cancer Cell States. 2019-11-01 10.1016/j.trecan.2019.09.002 2 view
Ma Front Microbiol Single-Cell RNA Sequencing of Plant-Associated Bacterial Communities. 2019-11-01 10.3389/fmicb.2019.02452 view
Zhang J Cancer The transcriptome difference between colorectal tumor and normal tissues revealed by single-cell sequencing. 2019-11-01 10.7150/jca.32267 3 view
Fuchs Front Immunol Gene Expression-Based Identification of Antigen-Responsive CD8+ T Cells on a Single-Cell Level. 2019-11-01 10.3389/fimmu.2019.02568 view
Zhang Front Oncol The Tumor Suppressor Role of Zinc Finger Protein 671 (ZNF671) in Multiple Tumors Based on Cancer Single-Cell Sequencing. 2019-11-01 10.3389/fonc.2019.01214 view
Zhang Cell Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma. 2019-10-31 10.1016/j.cell.2019.10.003 view
Niu Science Dissecting primate early post-implantation development using long-term in vitro embryo culture. 2019-10-31 10.1126/science.aaw5754 10 view
Ma Science In vitro culture of cynomolgus monkey embryos beyond early gastrulation. 2019-10-31 10.1126/science.aax7890 view
Raghunathan J. Mol. Cell. Cardiol. Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. 2019-10-31 10.1016/j.yjmcc.2019.09.015 2 view
Finno iScience Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency. 2019-10-31 10.1016/j.isci.2019.10.064 view
Martini Circulation Single Cell Sequencing of Mouse Heart Immune Infiltrate in Pressure Overload-Driven Heart Failure Reveals Extent of Immune Activation. 2019-10-30 10.1161/CIRCULATIONAHA.119.041694 9 view
Herting Brain Tumour-associated macrophage-derived interleukin-1 mediates glioblastoma-associated cerebral oedema. 2019-10-30 10.1093/brain/awz331 view
Cordes Bioinformatics ImSpectR - R package to quantify immune repertoire diversity in spectratype and repertoire sequencing data. 2019-10-30 10.1093/bioinformatics/btz804 1 view
Papatheodorou Nucleic Acids Res. Expression Atlas update: from tissues to single cells. 2019-10-30 10.1093/nar/gkz947 12 view
Fitzgerald Proc. Natl. Acad. Sci. U.S.A. Self-renewing endometrial epithelial organoids of the human uterus. 2019-10-30 10.1073/pnas.1915389116 2 view
Mongia J. Comput. Biol. deepMc: Deep Matrix Completion for Imputation of Single-Cell RNA-seq Data. 2019-10-29 10.1089/cmb.2019.0278 6 view
Vgontzas Cephalalgia Migraine-associated gene expression in cell types of the central and peripheral nervous system. 2019-10-29 10.1177/0333102419877834 view
Oakes Cancer Res. Metastatic conditioning of myeloid cells at a subcutaneous synthetic niche reflects disease progression and predicts therapeutic outcomes. 2019-10-29 10.1158/0008-5472.CAN-19-1932 view
Cai Elife A chemical probe of CARM1 alters epigenetic plasticity against breast cancer cell invasion. 2019-10-28 10.7554/eLife.47110 2 view
Wang PLoS Comput. Biol. SCMarker: Ab initio marker selection for single cell transcriptome profiling. 2019-10-28 10.1371/journal.pcbi.1007445 view
Andreyev Trends Biotechnol. Integration of Flow Cytometry and Single Cell Sequencing. 2019-10-28 10.1016/j.tibtech.2019.09.002 view
Zhang World J Stem Cells Applications of single cell RNA sequencing to research of stem cells. 2019-10-26 10.4252/wjsc.v11.i10.722 1 view
Milliron Circ. Res. Isolation of Cardiomyocytes Undergoing Mitosis with Complete Cytokinesis. 2019-10-25 10.1161/CIRCRESAHA.119.314908 1 view
Lam Genes Cells Single cell study of neural stem cells derived from human iPSCs reveal distinct progenitor populations with neurogenic and gliogenic potential. 2019-10-25 10.1111/gtc.12731 view
Menon Nat Commun Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration. 2019-10-25 10.1038/s41467-019-12780-8 6 view
Wyler Nat Commun Single-cell RNA-sequencing of herpes simplex virus 1-infected cells connects NRF2 activation to an antiviral program. 2019-10-25 10.1038/s41467-019-12894-z view
Ding Nat Commun Biological process activity transformation of single cell gene expression for cross-species alignment. 2019-10-25 10.1038/s41467-019-12924-w view
Dobie Curr Opin Pharmacol Unravelling fibrosis using single-cell transcriptomics. 2019-10-25 10.1016/j.coph.2019.09.004 2 view
Li Blood Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia. 2019-10-24 10.1182/blood.2019002220 11 view
Ren Elife Single-cell transcriptomes and whole-brain projections of serotonin neurons in the mouse dorsal and median raphe nuclei. 2019-10-24 10.7554/eLife.49424 9 view
Wang Bioinformatics SINC: a scale-invariant deep-neural-network classifier for bulk and single-cell RNA-seq data. 2019-10-24 10.1093/bioinformatics/btz801 view
Castillo-Lara Bioinformatics PlanExp: intuitive integration of complex RNA-seq datasets with planarian omics resources. 2019-10-24 10.1093/bioinformatics/btz802 view
Shi Genome Res. Single-pollen-cell sequencing for gamete-based phased diploid genome assembly in plants. 2019-10-24 10.1101/gr.251033.119 3 view
Jewell Am. J. Pathol. Single cell RNA sequencing identifies YAP1-dependent hepatic mesothelial progenitors in fibrolamellar carcinoma. 2019-10-24 10.1016/j.ajpath.2019.09.018 view
Sekiguchi J. Dent. Res. Single-Cell RNA-seq Identifies Cell Diversity in Embryonic Salivary Glands. 2019-10-23 10.1177/0022034519883888 view
Yang FASEB J. Inhibiting repressive epigenetic modification promotes telomere rejuvenation in somatic cell reprogramming. 2019-10-23 10.1096/fj.201901486RR view
Eling Cell Syst Correcting the Mean-Variance Dependency for Differential Variability Testing Using Single-Cell RNA Sequencing Data. 2019-10-23 10.1016/j.cels.2019.08.003 view
Zhao Brief. Bioinformatics Evaluation of single-cell classifiers for single-cell RNA sequencing data sets. 2019-10-23 10.1093/bib/bbz096 2 view
Wulf J. Biol. Chem. Non-templated addition and template switching by MMLV-based reverse transcriptases co-occur and compete with each other. 2019-10-22 10.1074/jbc.RA119.010676 view
Kondratova Nat Commun A multiscale signalling network map of innate immune response in cancer reveals cell heterogeneity signatures. 2019-10-22 10.1038/s41467-019-12270-x view
Singh Blood Adv Generation and function of progenitor T cells from StemRegenin-1-expanded CD34+ human hematopoietic progenitor cells. 2019-10-22 10.1182/bloodadvances.2018026575 view
Mironova Curr. Opin. Plant Biol. A single-cell view of tissue regeneration in plants. 2019-10-22 10.1016/j.pbi.2019.09.003 1 view
Carter Cell Syst Bayesian Inference of Allelic Inclusion Rates in the Human T Cell Receptor Repertoire. 2019-10-22 10.1016/j.cels.2019.09.006 view
Villani Stem Cells Transl Med SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester. 2019-10-21 10.1002/sctm.19-0231 view
House Clin. Cancer Res. Macrophage derived CXCL9 and CXCL10 are required for anti-tumor immune responses following immune checkpoint blockade. 2019-10-21 10.1158/1078-0432.CCR-19-1868 1 view
West Proc. Natl. Acad. Sci. U.S.A. Dynamics of trophoblast differentiation in peri-implantation-stage human embryos. 2019-10-21 10.1073/pnas.1911362116 view
Gonzales Proc. Natl. Acad. Sci. U.S.A. Subregion-specific rules govern the distribution of neuronal immediate-early gene induction. 2019-10-21 10.1073/pnas.1913658116 2 view
Gomes Trends Immunol. Immunology Driven by Large-Scale Single-Cell Sequencing. 2019-10-20 10.1016/ 18 view
Liu Cytogenet. Genome Res. Single-Cell Sequencing Reveals the Relationship between Phenotypes and Genotypes of Klinefelter Syndrome. 2019-10-19 10.1159/000503737 view
Mazzone Mol. Neurobiol. Transcriptional Profiling of Individual Airway Projecting Vagal Sensory Neurons. 2019-10-19 10.1007/s12035-019-01782-8 4 view
Xu J. Pathol. Clarin-1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome. 2019-10-18 10.1002/path.5360 view
Arisdakessian Genome Biol. DeepImpute: an accurate, fast, and scalable deep neural network method to impute single-cell RNA-seq data. 2019-10-18 10.1186/s13059-019-1837-6 14 view
Malikic Genome Res. PhISCS: a combinatorial approach for subperfect tumor phylogeny reconstruction via integrative use of single-cell and bulk sequencing data. 2019-10-18 10.1101/gr.234435.118 14 view
Alisjahbana Biochem. Pharmacol. Human Macrophages and Innate Lymphoid Cells: Tissue-resident Innate Immunity in Humanized Mice. 2019-10-18 10.1016/j.bcp.2019.113672 4 view
Kalvala J Clin Med Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS. 2019-10-18 10.3390/jcm8101726 2 view
Genovese J. Physiol. (Lond.) TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels. 2019-10-17 10.1113/JP278784 6 view
Oyelakin J. Dent. Res. Transcriptomic and Single-Cell Analysis of the Murine Parotid Gland. 2019-10-17 10.1177/0022034519882355 view
O'Flanagan Genome Biol. Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses. 2019-10-17 10.1186/s13059-019-1830-0 view
Szabo Nat Commun Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease. 2019-10-17 10.1038/s41467-019-12464-3 4 view
Kim Cell Multimodal Analysis of Cell Types in a Hypothalamic Node Controlling Social Behavior. 2019-10-17 10.1016/j.cell.2019.09.020 17 view
Saurty-Seerunghen Acta Neuropathol Commun Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells. 2019-10-16 10.1186/s40478-019-0819-y 1 view
Danopoulos Eur. Respir. J. Transcriptional Characterisation of Human Lung Cells Identifies Novel Mesenchymal Lineage Markers. 2019-10-16 10.1183/13993003.00746-2019 4 view
Arendt Trends Genet. Many Ways to Build a Polyp. 2019-10-16 10.1016/j.tig.2019.09.003 view
Wang Adv Sci (Weinh) The CRISPR-Cas13a Gene-Editing System Induces Collateral Cleavage of RNA in Glioma Cells. 2019-10-16 10.1002/advs.201901299 8 view
Lobentanzer Cell Rep Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder. 2019-10-15 10.1016/j.celrep.2019.09.017 1 view
Xu Immunity Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. 2019-10-15 10.1016/j.immuni.2019.09.004 1 view
Zhou Cell Syst Single-Cell Analysis Reveals Regulatory Gene Expression Dynamics Leading to Lineage Commitment in Early T Cell Development. 2019-10-15 10.1016/j.cels.2019.09.008 4 view
Hsu Br. J. Haematol. Molecular heterogeneity unravelled by single-cell transcriptomics in patients with essential thrombocythaemia. 2019-10-14 10.1111/bjh.16225 view
Chen Nat. Biotechnol. High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell. 2019-10-14 10.1038/s41587-019-0290-0 23 view
Chew Genes (Basel) Transcriptional Networks of Microglia in Alzheimer's Disease and Insights into Pathogenesis. 2019-10-12 10.3390/genes10100798 view
Kim Bioinformatics Cancer classification of single cell gene expression data by neural network. 2019-10-11 10.1093/bioinformatics/btz772 1 view
Ordoñez-Rueda Cytometry A Apoptotic Cell Exclusion and Bias-Free Single-Cell Selection Are Important Quality Control Requirements for Successful Single-Cell Sequencing Applications. 2019-10-11 10.1002/cyto.a.23898 1 view
Baran Genome Biol. MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions. 2019-10-11 10.1186/s13059-019-1812-2 view
Sommerfeld Sci Immunol Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis. 2019-10-11 10.1126/sciimmunol.aax4783 1 view
Perciani Sci Immunol Lifting the veil on macrophage diversity in tissue regeneration and fibrosis. 2019-10-11 10.1126/sciimmunol.aaz0749 1 view
Vieth Nat Commun A systematic evaluation of single cell RNA-seq analysis pipelines. 2019-10-11 10.1038/s41467-019-12266-7 12 view
Miklas Nat Commun TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes. 2019-10-11 10.1038/s41467-019-12482-1 view
Der Nat. Immunol. Author Correction: Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. 2019-10-11 10.1038/s41590-019-0529-4 view
Zhang Cancer Lett. Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases. 2019-10-11 10.1016/j.canlet.2019.10.016 view
Joshi Eur. Respir. J. A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signaling in monocyte-derived alveolar macrophages. 2019-10-10 10.1183/13993003.00646-2019 view
Zeng Nat Commun DC3 is a method for deconvolution and coupled clustering from bulk and single-cell genomics data. 2019-10-10 10.1038/s41467-019-12547-1 13 view
Arvanitis Nat. Rev. Cancer The blood-brain barrier and blood-tumour barrier in brain tumours and metastases. 2019-10-10 10.1038/s41568-019-0205-x 11 view
Lv PLoS Biol. Single-cell RNA sequencing reveals regulatory mechanism for trophoblast cell-fate divergence in human peri-implantation conceptuses. 2019-10-09 10.1371/journal.pbio.3000187 6 view
Baruzzo Bioinformatics SPARSim Single Cell: a count data simulator for scRNA-seq data. 2019-10-09 10.1093/bioinformatics/btz752 1 view
Nguyen Elife Stereotyped transcriptomic transformation of somatosensory neurons in response to injury. 2019-10-08 10.7554/eLife.49679 view
Behura Pharmacol. Res. The Brain-Placental Axis: Therapeutic and Pharmacological Relevancy to Pregnancy. 2019-10-07 10.1016/j.phrs.2019.104468 view
Liao IEEE/ACM Trans Comput Biol Bioinform EPGA-SC : A framework for de novo assembly of single-cell sequencing reads. 2019-10-07 10.1109/TCBB.2019.2945761 view
Chen Immunity TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. 2019-10-07 10.1016/j.immuni.2019.09.013 view
Cerniauskas Neuron Chronic Stress Induces Activity, Synaptic, and Transcriptional Remodeling of the Lateral Habenula Associated with Deficits in Motivated Behaviors. 2019-10-07 10.1016/j.neuron.2019.09.005 5 view
Suryawanshi Cardiovasc. Res. Cell atlas of the fetal human heart and implications for autoimmune-mediated congenital heart block. 2019-10-07 10.1093/cvr/cvz257 3 view
Bolognini Bioinformatics VISOR: a versatile haplotype-aware structural variant simulator for short and long read sequencing. 2019-10-07 10.1093/bioinformatics/btz719 view
Radermecker Nat. Immunol. Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps. 2019-10-07 10.1038/s41590-019-0496-9 view
Penaloza Biochem. Biophys. Res. Commun. Single-cell RNA-seq analysis of Mesp1-induced skeletal myogenic development. 2019-10-05 10.1016/j.bbrc.2019.09.140 1 view
Tang Bioinformatics bayNorm: Bayesian gene expression recovery, imputation and normalisation for single cell RNA-sequencing data. 2019-10-04 10.1093/bioinformatics/btz726 4 view
Maruggi Cancer Res. Absence of HIF1A leads to glycogen accumulation and an inflammatory response that enables pancreatic tumor growth. 2019-10-04 10.1158/0008-5472.CAN-18-2994 view
Lu Neurosci. Lett. Electrophysiological characterization of acutely isolated spiral ganglion neurons in neonatal and mature sonic hedgehog knock-in mice. 2019-10-04 10.1016/j.neulet.2019.134536 view
Zeng Immunity Single-Cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos. 2019-10-03 10.1016/j.immuni.2019.09.008 view
Abbas Hum. Reprod. Tissue stiffness at the human maternal-fetal interface. 2019-10-03 10.1093/humrep/dez139 view
Travnickova Cancer Res. Zebrafish MITF-low melanoma subtype models reveal transcriptional subclusters and MITF-independent residual disease. 2019-10-03 10.1158/0008-5472.CAN-19-0037 3 view
Singh Development CDK2 kinase activity is a regulator of male germ cell fate. 2019-10-03 10.1242/dev.180273 view
Baron Cell Cell Type Purification by Single-Cell Transcriptome-Trained Sorting. 2019-10-03 10.1016/j.cell.2019.08.006 2 view
Walker Dev. Biol. Alveolar progenitor cells in the mammary gland are dependent on the β4 integrin. 2019-10-03 10.1016/j.ydbio.2019.10.001 1 view
Mu Genomics Proteomics Bioinformatics Deciphering Brain Complexity Using Single-cell Sequencing. 2019-10-03 10.1016/j.gpb.2018.07.007 view
Zwarycz Cell Mol Gastroenterol Hepatol IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model. 2019-10-01 10.1016/j.jcmgh.2018.06.008 10 view
Mahmoudi Nature Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. 2019-10-01 10.1038/s41586-019-1658-5 view
Nazzicari Front Genet MTGO-SC, A Tool to Explore Gene Modules in Single-Cell RNA Sequencing Data. 2019-10-01 10.3389/fgene.2019.00953 view
Cheng Front Genet Microbiome Big-Data Mining and Applications Using Single-Cell Technologies and Metagenomics Approaches Toward Precision Medicine. 2019-10-01 10.3389/fgene.2019.00972 view
Delaney Mol. Syst. Biol. Combinatorial prediction of marker panels from single-cell transcriptomic data. 2019-10-01 10.15252/msb.20199005 view
Taguchi Front Genet Tensor Decomposition-Based Unsupervised Feature Extraction Applied to Single-Cell Gene Expression Analysis. 2019-10-01 10.3389/fgene.2019.00864 2 view
Wang Front Genet SCDevDB: A Database for Insights Into Single-Cell Gene Expression Profiles During Human Developmental Processes. 2019-10-01 10.3389/fgene.2019.00903 view
Coon Front Endocrinol (Lausanne) Single Cell Sequencing of the Pineal Gland: The Next Chapter. 2019-10-01 10.3389/fendo.2019.00590 view
Li Anal. Chem. A Centrifugal-Driven Droplet Generation Method with Minimal Waste for Single-Cell Whole Genome Amplification. 2019-10-01 10.1021/acs.analchem.9b02786 view
Dick Front Immunol Using High-Dimensional Approaches to Probe Monocytes and Macrophages in Cardiovascular Disease. 2019-10-01 10.3389/fimmu.2019.02146 view
Vishvanath J. Clin. Invest. Contribution of adipogenesis to healthy adipose tissue expansion in obesity. 2019-10-01 10.1172/JCI129191 32 view
Kanton Nature Organoid single-cell genomic atlas uncovers human-specific features of brain development. 2019-10-01 10.1038/s41586-019-1654-9 30 view
Reichhardt Front Immunol Complement in Human Pre-implantation Embryos: Attack and Defense. 2019-10-01 10.3389/fimmu.2019.02234 view
Lombard-Banek Meth. Enzymol. Single-cell proteomics in complex tissues using microprobe capillary electrophoresis mass spectrometry. 2019-10-01 10.1016/bs.mie.2019.07.001 view
Song J. Clin. Invest. Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue. 2019-10-01 10.1172/JCI129167 8 view
Chen Gigascience IKAP-Identifying K mAjor cell Population groups in single-cell RNA-sequencing analysis. 2019-10-01 10.1093/gigascience/giz121 view
Gruber Cancer Discov Single-Cell RNA Sequencing Reveals a Developmental Hierarchy in Langerhans Cell Histiocytosis. 2019-10-01 10.1158/2159-8290.CD-19-0820 view
Xie Oncogene Proteasome inhibitor induced SIRT1 deacetylates GLI2 to enhance hedgehog signaling activity and drug resistance in multiple myeloma. 2019-10-01 10.1038/s41388-019-1037-6 1 view
Wang IEEE J Biomed Health Inform Pathway-based Single-Cell RNA-Seq Classification, Clustering, and Construction of Gene-Gene Interactions Networks Using Random Forests. 2019-10-01 10.1109/JBHI.2019.2944865 view
Larsson Nat. Struct. Mol. Biol. X-chromosome upregulation is driven by increased burst frequency. 2019-10-01 10.1038/s41594-019-0306-y view
Günther Front Immunol Mind the Map: Technology Shapes the Myeloid Cell Space. 2019-10-01 10.3389/fimmu.2019.02287 view
Chen Fa Yi Xue Za Zhi Advancements in Single-cell Sequencing and the Prospect of Its Forensic Application. 2019-10-01 10.12116/j.issn.1004-5619.2019.05.017 view
Cheng Nucleic Acids Res. Latent cellular analysis robustly reveals subtle diversity in large-scale single-cell RNA-seq data. 2019-09-30 10.1093/nar/gkz826 1 view
Genovese Elife Coopted temporal patterning governs cellular hierarchy, heterogeneity and metabolism in Drosophila neuroblast tumors. 2019-09-30 10.7554/eLife.50375 view
Beltrán J. Clin. Invest. Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis. 2019-09-30 10.1172/JCI128475 1 view
Im J. Biol. Chem. Mass cytometry-based single-cell analysis of human stem cell reprogramming uncovers differential regulation of specific pluripotency markers. 2019-09-30 10.1074/jbc.RA119.009061 view
Redwood J. Allergy Clin. Immunol. Single cell transcriptomics reveal polyclonal memory T cell responses in abacavir patch test positive skin. 2019-09-28 10.1016/j.jaci.2019.09.013 view
Geng FEBS Lett. Single-cell RNA sequencing reveals chemokine self-feeding of myeloma cells promotes extramedullary metastasis. 2019-09-27 10.1002/1873-3468.13623 view
Santos Nat Commun Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity. 2019-09-27 10.1038/s41467-019-12307-1 view
Stewart Science Spatiotemporal immune zonation of the human kidney. 2019-09-27 10.1126/science.aat5031 view
Bhetraratana Arch. Biochem. Biophys. Diesel exhaust particles dysregulate multiple immunological pathways in murine macrophages: Lessons from microarray and scRNA-seq technologies. 2019-09-27 10.1016/ view
Tellechea J. Invest. Dermatol. Topical Application Of A Mast Cell Stabilizer Improves Impaired Diabetic Wound Healing. 2019-09-27 10.1016/j.jid.2019.08.449 view
Sun Cells An Efficient and Flexible Method for Deconvoluting Bulk RNA-Seq Data with Single-Cell RNA-Seq Data. 2019-09-27 10.3390/cells8101161 1 view
Ruiz García Development Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures. 2019-09-26 10.1242/dev.177428 view
Ryu Clin. Cancer Res. Alterations in the transcriptional programs of myeloma cells and the microenvironment during extramedullary progression affect proliferation and immune evasion. 2019-09-26 10.1158/1078-0432.CCR-19-0694 2 view
Xiao Genes Dev. Hippo pathway deletion in adult resting cardiac fibroblasts initiates a cell state transition with spontaneous and self-sustaining fibrosis. 2019-09-26 10.1101/gad.329763.119 view
DeTomaso Nat Commun Functional interpretation of single cell similarity maps. 2019-09-26 10.1038/s41467-019-12235-0 9 view
Cadwell Neuron Development and Arealization of the Cerebral Cortex. 2019-09-25 10.1016/j.neuron.2019.07.009 8 view
Upadhye Circ. Res. Diversification and CXCR4-Dependent Establishment of the Bone Marrow B-1a Cell Pool Governs Atheroprotective IgM Production Linked To Human Coronary Atherosclerosis. 2019-09-24 10.1161/CIRCRESAHA.119.315786 2 view
Ribeiro Int J Mol Sci Cytogenetics and Cytogenomics Evaluation in Cancer. 2019-09-23 10.3390/ijms20194711 view
Little Proc. Natl. Acad. Sci. U.S.A. Transcriptional control of lung alveolar type 1 cell development and maintenance by NK homeobox 2-1. 2019-09-23 10.1073/pnas.1906663116 view
Mameishvili Proc. Natl. Acad. Sci. U.S.A. Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer. 2019-09-23 10.1073/pnas.1901075116 1 view
Ye Nat. Biotechnol. In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma. 2019-09-23 10.1038/s41587-019-0246-4 view
Hrvatin Elife A scalable platform for the development of cell-type-specific viral drivers. 2019-09-23 10.7554/eLife.48089 3 view
Verhulst Cells Meta-Analysis of Human and Mouse Biliary Epithelial Cell Gene Profiles. 2019-09-20 10.3390/cells8101117 2 view
Wen Mol. Cell Human Germline Cell Development: from the Perspective of Single-Cell Sequencing. 2019-09-20 10.1016/j.molcel.2019.08.025 2 view
Fang Nat Commun Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development. 2019-09-20 10.1038/s41467-019-12325-z view
Majka Compr Physiol Mesenchymal Regulation of the Microvascular Niche in Chronic Lung Diseases. 2019-09-19 10.1002/cphy.c180043 view
Wang Aging (Albany NY) Single-cell RNA-seq reveals RAD51AP1 as a potent mediator of EGFRvIII in human glioblastomas. 2019-09-18 10.18632/aging.102282 view
Schoonen Mol Oncol Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling and cytotoxicity in BRCA2-deficient cancer cells. 2019-09-17 10.1002/1878-0261.12573 1 view
Kanev Proc. Natl. Acad. Sci. U.S.A. Proliferation-competent Tcf1+ CD8 T cells in dysfunctional populations are CD4 T cell help independent. 2019-09-17 10.1073/pnas.1902701116 view
Yu Bioinformatics SCSsim: an integrated tool for simulating single-cell genome sequencing data. 2019-09-17 10.1093/bioinformatics/btz713 view
Tarashansky Elife Self-assembling manifolds in single-cell RNA sequencing data. 2019-09-16 10.7554/eLife.48994 6 view
Sun PLoS Genet. Chromosome-wide co-fluctuation of stochastic gene expression in mammalian cells. 2019-09-16 10.1371/journal.pgen.1008389 view
Harold Proc. Natl. Acad. Sci. U.S.A. Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition. 2019-09-16 10.1073/pnas.1907154116 4 view
DePasquale Nucleic Acids Res. cellHarmony: cell-level matching and holistic comparison of single-cell transcriptomes. 2019-09-16 10.1093/nar/gkz789 5 view
Stevenson J. Biomol. Struct. Dyn. Single-cell RNA-Seq: a next generation sequencing tool for a high-resolution view of the individual cell. 2019-09-15 10.1080/07391102.2019.1659859 view
Bhattacherjee Nat Commun Cell type-specific transcriptional programs in mouse prefrontal cortex during adolescence and addiction. 2019-09-13 10.1038/s41467-019-12054-3 view
Tsankov Development Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression. 2019-09-12 10.1242/dev.174722 view
Finotello Nat. Rev. Genet. Next-generation computational tools for interrogating cancer immunity. 2019-09-12 10.1038/s41576-019-0166-7 15 view
Turnquist Expert Rev Anticancer Ther Tumour heterogeneity: does it matter? 2019-09-11 10.1080/14737140.2019.1667236 view
Chang Cells Single-Cell Transcriptomes Reveal Characteristic Features of Mouse Hepatocytes with Liver Cholestatic Injury. 2019-09-11 10.3390/cells8091069 view
Blauwendraat Lancet Neurol The genetic architecture of Parkinson's disease. 2019-09-11 10.1016/S1474-4422(19)30287-X view
Mao Stem Cell Reports Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. 2019-09-11 10.1016/j.stemcr.2019.08.012 view
John Bioinformatics Spectrum: Fast density-aware spectral clustering for single and multi-omic data. 2019-09-10 10.1093/bioinformatics/btz704 3 view
Shulman Nucleic Acids Res. Cell-type-specific analysis of alternative polyadenylation using single-cell transcriptomics data. 2019-09-10 10.1093/nar/gkz781 4 view
Bais Bioinformatics scds: Computational Annotation of Doublets in Single-Cell RNA Sequencing Data. 2019-09-10 10.1093/bioinformatics/btz698 view
Xie Bioinformatics QUBIC2: A novel and robust biclustering algorithm for analyses and interpretation of large-scale RNA-Seq data. 2019-09-10 10.1093/bioinformatics/btz692 view
Zhang J. Clin. Invest. Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice. 2019-09-10 10.1172/JCI130239 12 view
Abdelaal Genome Biol. A comparison of automatic cell identification methods for single-cell RNA sequencing data. 2019-09-09 10.1186/s13059-019-1795-z 26 view
Li Genome Biol. scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data. 2019-09-09 10.1186/s13059-019-1806-0 2 view
Zeng Cell Res. Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing. 2019-09-09 10.1038/s41422-019-0228-6 7 view
Zhang Nat. Methods Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling. 2019-09-09 10.1038/s41592-019-0529-1 17 view
Haremaki Nat. Biotechnol. Self-organizing neuruloids model developmental aspects of Huntington's disease in the ectodermal compartment. 2019-09-09 10.1038/s41587-019-0237-5 view
Yap Toxicon Expansion of Hydra actinoporin-like toxin (HALT) gene family: Expression divergence and functional convergence evolved through gene duplication. 2019-09-09 10.1016/j.toxicon.2019.09.007 view
Hamey Exp. Hematol. Machine learning predicts putative haematopoietic stem cells within large single-cell transcriptomics datasets. 2019-09-09 10.1016/j.exphem.2019.08.009 view
Vafaizadeh J Mammary Gland Biol Neoplasia The Eleventh ENBDC Workshop: Advances in Technology Help to Unveil Mechanisms of Mammary Gland Development and Cancerogenesis. 2019-09-07 10.1007/s10911-019-09436-0 view
Michaelis Brain Behav. Immun. Persistent Toll-like receptor 7 stimulation induces behavioral and molecular innate immune tolerance. 2019-09-06 10.1016/j.bbi.2019.09.004 view
Ye Bioinformatics scDAPA: detection and visualization of dynamic alternative polyadenylation from single cell RNA-seq data. 2019-09-06 10.1093/bioinformatics/btz701 1 view
Zhang Cell Syst Valid Post-clustering Differential Analysis for Single-Cell RNA-Seq. 2019-09-06 10.1016/j.cels.2019.07.012 5 view
Pang Mol Oncol Single-cell RNA-seq reveals the invasive trajectory and molecular cascades underlying glioblastoma progression. 2019-09-05 10.1002/1878-0261.12569 2 view
Moutaoufik iScience Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis. 2019-09-04 10.1016/j.isci.2019.08.057 2 view
Bockerstett Gut Single-cell transcriptional analyses of spasmolytic polypeptide-expressing metaplasia arising from acute drug injury and chronic inflammation in the stomach. 2019-09-03 10.1136/gutjnl-2019-318930 2 view
Schyns Nat Commun Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung. 2019-09-03 10.1038/s41467-019-11843-0 25 view
Hong Nat Commun Single-cell transcriptomics reveals multi-step adaptations to endocrine therapy. 2019-09-02 10.1038/s41467-019-11721-9 view
Yang Nat Commun Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome. 2019-09-02 10.1038/s41467-019-11947-7 4 view
Alessandrì Gigascience rCASC: reproducible classification analysis of single-cell sequencing data. 2019-09-01 10.1093/gigascience/giz105 view
Tao Cancer Manag Res Postoperative metastasis prediction based on portal vein circulating tumor cells detected by flow cytometry in periampullary or pancreatic cancer. 2019-09-01 10.2147/CMAR.S210332 1 view
Dominguez-Gutierrez Mol Metab Heterogeneity of human pancreatic β-cells. 2019-09-01 10.1016/j.molmet.2019.06.015 3 view
Finnegan Front Genet Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators. 2019-09-01 10.3389/fgene.2019.00775 4 view
Shafer Front Cell Dev Biol Cross-Species Analysis of Single-Cell Transcriptomic Data. 2019-09-01 10.3389/fcell.2019.00175 3 view
He Evodevo Cnidofest 2018: the future is bright for cnidarian research. 2019-09-01 10.1186/s13227-019-0134-5 view
Hajkarim J Lipid Atheroscler Single Cell RNA-Sequencing for the Study of Atherosclerosis. 2019-09-01 10.12997/jla.2019.8.2.152 view
Cool Mol. Biol. Cell Spatial and temporal tools for building a human cell atlas. 2019-09-01 10.1091/mbc.E18-10-0667 1 view
Mair Methods Mol. Biol. High-Dimensional Immunophenotyping with Fluorescence-Based Cytometry: A Practical Guidebook. 2019-09-01 10.1007/978-1-4939-9650-6_1 view
Ziqing Methods Mol. Biol. Strategies and Techniques for NK Cell Phenotyping. 2019-09-01 10.1007/978-1-4939-9650-6_6 view
Wang Nat. Methods Data denoising with transfer learning in single-cell transcriptomics. 2019-09-01 10.1038/s41592-019-0537-1 view
Lin Gigascience Evaluating stably expressed genes in single cells. 2019-09-01 10.1093/gigascience/giz106 7 view
McFaline-Figueroa Nat. Genet. A pooled single-cell genetic screen identifies regulatory checkpoints in the continuum of the epithelial-to-mesenchymal transition. 2019-09-01 10.1038/s41588-019-0489-5 3 view
Ben-Moshe Nat Metab Spatial sorting enables comprehensive characterization of liver zonation. 2019-09-01 10.1038/s42255-019-0109-9 7 view
Sharir Nat. Cell Biol. A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage. 2019-09-01 10.1038/s41556-019-0378-2 4 view
Yang F1000Res Scavenger: A pipeline for recovery of unaligned reads utilising similarity with aligned reads. 2019-09-01 10.12688/f1000research.19426.1 view
Hu PLoS Comput. Biol. PanoView: An iterative clustering method for single-cell RNA sequencing data. 2019-08-30 10.1371/journal.pcbi.1007040 view
Tan Autophagy Dissecting dynamic expression of autophagy-related genes during human fetal digestive tract development via single-cell RNA sequencing. 2019-08-30 10.1080/15548627.2019.1656956 view
Dion-Côté Elife A hotspot for new genes. 2019-08-29 10.7554/eLife.50136 view
Lv Biol. Res. Light-induced injury in mouse embryos revealed by single-cell RNA sequencing. 2019-08-29 10.1186/s40659-019-0256-1 2 view
Yin Mol. Cell High-Throughput Single-Cell Sequencing with Linear Amplification. 2019-08-28 10.1016/j.molcel.2019.08.002 5 view
Wang Biomater Sci Cardiomyocyte dedifferentiation and remodeling in 3D scaffolds to generate the cellular diversity of engineering cardiac tissues. 2019-08-28 10.1039/c9bm01003c view
Laurentino Clin Epigenetics High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting. 2019-08-28 10.1186/s13148-019-0720-3 3 view
Yu J. Am. Soc. Nephrol. Single-Cell Transcriptomic Map of the Human and Mouse Bladders. 2019-08-28 10.1681/ASN.2019040335 view
Aldinger Am. J. Hum. Genet. Redefining the Etiologic Landscape of Cerebellar Malformations. 2019-08-28 10.1016/j.ajhg.2019.07.019 1 view
Schnepp Hum. Mol. Genet. SNV identification from single-cell RNA sequencing data. 2019-08-27 10.1093/hmg/ddz207 3 view
Feng BMC Genomics Single Cell Explorer, collaboration-driven tools to leverage large-scale single cell RNA-seq data. 2019-08-27 10.1186/s12864-019-6053-y 2 view
Namchaiw Stem Cell Res Ther Temporal and partial inhibition of GLI1 in neural stem cells (NSCs) results in the early maturation of NSC derived oligodendrocytes in vitro. 2019-08-27 10.1186/s13287-019-1374-y 1 view
He Gastroenterology Interleukin 1 beta and Matrix Metallopeptidase 3 Contribute to Development of EGFR-dependent Serrated Polyps in Mouse Cecum. 2019-08-27 10.1053/j.gastro.2019.08.025 view
Chen Bioinformatics Tissue-specific deconvolution of immune cell composition by integrating bulk and single-cell transcriptomes. 2019-08-26 10.1093/bioinformatics/btz672 view
Yu Elife Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish. 2019-08-23 10.7554/eLife.48660 view
Zheng IEEE Trans Biomed Eng scRCMF: Identification of cell subpopulations and transition states from single cell transcriptomes. 2019-08-23 10.1109/TBME.2019.2937228 view
de Couto Arterioscler. Thromb. Vasc. Biol. Mechanism of Enhanced MerTK-Dependent Macrophage Efferocytosis by Extracellular Vesicles. 2019-08-22 10.1161/ATVBAHA.119.313115 view
Lukowski EMBO J. A single-cell transcriptome atlas of the adult human retina. 2019-08-22 10.15252/embj.2018100811 33 view
Torang BMC Bioinformatics An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets. 2019-08-22 10.1186/s12859-019-2994-z view
Li Nat Commun B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis. 2019-08-22 10.1038/s41467-019-11746-0 1 view
Desanti De Oliveira Nat Rev Nephrol Molecular nephrology: types of acute tubular injury. 2019-08-22 10.1038/s41581-019-0184-x view
Zhang Am. J. Physiol. Lung Cell Mol. Physiol. GDF15 is an epithelial-derived biomarker of idiopathic pulmonary fibrosis. 2019-08-21 10.1152/ajplung.00062.2019 6 view
Ding Am. J. Physiol. Lung Cell Mol. Physiol. Integrating multi-omics longitudinal data to reconstruct networks underlying lung development. 2019-08-21 10.1152/ajplung.00554.2018 view
Hemmers J. Exp. Med. IL-2 production by self-reactive CD4 thymocytes scales regulatory T cell generation in the thymus. 2019-08-21 10.1084/jem.20190993 view
Hodge Nature Conserved cell types with divergent features in human versus mouse cortex. 2019-08-21 10.1038/s41586-019-1506-7 207 view
Lau Gastroenterology Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on single-cell Transcriptome Analyses. 2019-08-20 10.1053/j.gastro.2019.08.019 view
Zhou Nucleic Acids Res. Global prediction of chromatin accessibility using small-cell-number and single-cell RNA-seq. 2019-08-20 10.1093/nar/gkz716 view
Parra Nucleic Acids Res. Reconstructing complex lineage trees from scRNA-seq data using MERLoT. 2019-08-20 10.1093/nar/gkz706 7 view
Legoux Nat. Immunol. Molecular mechanisms of lineage decisions in metabolite-specific T cells. 2019-08-20 10.1038/s41590-019-0465-3 6 view
Adriaenssens Cell Metab. Glucose-Dependent Insulinotropic Polypeptide Receptor-Expressing Cells in the Hypothalamus Regulate Food Intake. 2019-08-19 10.1016/j.cmet.2019.07.013 view
Winterer Eur. J. Neurosci. Single-cell RNA-Seq characterization of anatomically identified OLM interneurons in different transgenic mouse lines. 2019-08-17 10.1111/ejn.14549 1 view
Kannan Circ. Res. Large Particle Fluorescence-Activated Cell Sorting Enables High-Quality Single-Cell RNA Sequencing and Functional Analysis of Adult Cardiomyocytes. 2019-08-16 10.1161/CIRCRESAHA.119.315493 view
Witt Elife Testis single-cell RNA-seq reveals the dynamics of de novo gene transcription and germline mutational bias in Drosophila. 2019-08-16 10.7554/eLife.47138 view
Min Proc. Natl. Acad. Sci. U.S.A. Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells. 2019-08-16 10.1073/pnas.1906512116 11 view
Huisman Nat Commun Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators. 2019-08-16 10.1038/s41467-019-11667-y view
Köhler J. Invest. Dermatol. DNA Methylation in Epidermal Differentiation, Aging, and Cancer. 2019-08-16 10.1016/j.jid.2019.05.011 4 view
Suner Stat Appl Genet Mol Biol Clustering methods for single-cell RNA-sequencing expression data: performance evaluation with varying sample sizes and cell compositions. 2019-08-14 10.1515/sagmb-2019-0004 view
Huang Elife Molecular and anatomical organization of the dorsal raphe nucleus. 2019-08-14 10.7554/eLife.46464 9 view
Johansen Genome Biol. scAlign: a tool for alignment, integration, and rare cell identification from scRNA-seq data. 2019-08-14 10.1186/s13059-019-1766-4 view
Soares Proc. Natl. Acad. Sci. U.S.A. Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome. 2019-08-14 10.1073/pnas.1908180116 1 view
Petti Nat Commun A general approach for detecting expressed mutations in AML cells using single cell RNA-sequencing. 2019-08-14 10.1038/s41467-019-11591-1 12 view
Waickman Nat Commun Dissecting the heterogeneity of DENV vaccine-elicited cellular immunity using single-cell RNA sequencing and metabolic profiling. 2019-08-14 10.1038/s41467-019-11634-7 view
Zhang Cancer Cell Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse. 2019-08-14 10.1016/j.ccell.2019.07.009 view
Egerod Trends Neurosci. The Molecular Diversity of Vagal Afferents Revealed. 2019-08-14 10.1016/j.tins.2019.08.002 view
Durand Oncotarget ALK mutation dynamics and clonal evolution in a neuroblastoma model exhibiting two ALK mutations. 2019-08-13 10.18632/oncotarget.27119 1 view
Peng Cell Res. Author Correction: Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma. 2019-08-13 10.1038/s41422-019-0212-1 view
Cheng Cell Rep m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. 2019-08-13 10.1016/j.celrep.2019.07.032 3 view
Mallik Genes (Basel) Multi-Objective Optimized Fuzzy Clustering for Detecting Cell Clusters from Single-Cell Expression Profiles. 2019-08-13 10.3390/genes10080611 8 view
Devitt Virology Single-cell RNA sequencing reveals cell type-specific HPV expression in hyperplastic skin lesions. 2019-08-13 10.1016/j.virol.2019.08.007 view
Wang Genome Biol. BERMUDA: a novel deep transfer learning method for single-cell RNA sequencing batch correction reveals hidden high-resolution cellular subtypes. 2019-08-12 10.1186/s13059-019-1764-6 11 view
Valenzi Ann. Rheum. Dis. Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung disease. 2019-08-12 10.1136/annrheumdis-2018-214865 9 view
Bagadia Nat. Immunol. An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. 2019-08-12 10.1038/s41590-019-0449-3 19 view
Lin Cancers (Basel) Biological Significance of Tumor Heterogeneity in Esophageal Squamous Cell Carcinoma. 2019-08-12 10.3390/cancers11081156 1 view
Wang Bioinformatics Using multiple measurements of tissue to estimate subject- and cell-type-specific gene expression. 2019-08-10 10.1093/bioinformatics/btz619 7 view
Polański Bioinformatics BBKNN: Fast Batch Alignment of Single Cell Transcriptomes. 2019-08-10 10.1093/bioinformatics/btz625 29 view
Deng Bioinformatics Alternating EM algorithm for a bilinear model in isoform quantification from RNA-seq data. 2019-08-10 10.1093/bioinformatics/btz640 view
Yekelchyk Basic Res. Cardiol. Mono- and multi-nucleated ventricular cardiomyocytes constitute a transcriptionally homogenous cell population. 2019-08-09 10.1007/s00395-019-0744-z 3 view
Xiong Mol. Cell Landscape of Intercellular Crosstalk in Healthy and NASH Liver Revealed by Single-Cell Secretome Gene Analysis. 2019-08-08 10.1016/j.molcel.2019.07.028 45 view
Han Cell Stem Cell Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells. 2019-08-08 10.1016/j.stem.2019.07.008 6 view
Lee JCI Insight High-dimensional analysis reveals a pathogenic role of inflammatory monocytes in experimental diffuse alveolar hemorrhage. 2019-08-08 10.1172/jci.insight.129703 2 view
Ye Bioinformatics scHinter: Imputing dropout events for single-cell RNA-seq data with limited sample size. 2019-08-08 10.1093/bioinformatics/btz627 view
Norman Science Exploring genetic interaction manifolds constructed from rich single-cell phenotypes. 2019-08-08 10.1126/science.aax4438 8 view
Keener Nat. Med. Single-cell sequencing edges into clinical trials. 2019-08-07 10.1038/d41591-019-00017-6 view
Culemann Nature Locally renewing resident synovial macrophages provide a protective barrier for the joint. 2019-08-07 10.1038/s41586-019-1471-1 74 view
Liu J Am Heart Assoc Spatiotemporal Gene Coexpression and Regulation in Mouse Cardiomyocytes of Early Cardiac Morphogenesis. 2019-08-06 10.1161/JAHA.119.012941 1 view
Bucsan Pathog Dis The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease. 2019-08-05 10.1093/femspd/ftz037 1 view
O'Byrne Blood Discovery of a CD10 negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs. 2019-08-05 10.1182/blood.2019001289 view
Nishinakamura Nat Rev Nephrol Human kidney organoids: progress and remaining challenges. 2019-08-05 10.1038/s41581-019-0176-x 5 view
Payne Cancers (Basel) Circulating Tumour Cell Biomarkers in Head and Neck Cancer: Current Progress and Future Prospects. 2019-08-05 10.3390/cancers11081115 view
Qiu Circ. Res. Endothelial Cell Development and Its Application to Regenerative Medicine. 2019-08-02 10.1161/CIRCRESAHA.119.311405 view
Zhu Nucleic Acids Res. Nonparametric expression analysis using inferential replicate counts. 2019-08-02 10.1093/nar/gkz622 2 view
Wan Nucleic Acids Res. LTMG: a novel statistical modeling of transcriptional expression states in single-cell RNA-Seq data. 2019-08-02 10.1093/nar/gkz655 2 view
Liu Bioinformatics scRNABatchQC: Multi-samples quality control for single cell RNA-seq data. 2019-08-02 10.1093/bioinformatics/btz601 1 view
Kim Bioinformatics VirtualCytometry: a webserver for evaluating immune cell differentiation using single-cell RNA sequencing data. 2019-08-02 10.1093/bioinformatics/btz610 1 view
Rashidian Proc. Natl. Acad. Sci. U.S.A. Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade. 2019-08-02 10.1073/pnas.1905005116 3 view
Van Der Byl Methods Mol. Biol. Single-Cell Transcriptome Analysis of T Cells. 2019-08-01 10.1007/978-1-4939-9728-2_16 view
Gambardella Front Genet A Tool for Visualization and Analysis of Single-Cell RNA-Seq Data Based on Text Mining. 2019-08-01 10.3389/fgene.2019.00734 2 view
Highton Wellcome Open Res Single-cell transcriptome analysis of CD8 + T-cell memory inflation. 2019-08-01 10.12688/wellcomeopenres.15115.1 view
Takeda Immunity Single-Cell Survey of Human Lymphatics Unveils Marked Endothelial Cell Heterogeneity and Mechanisms of Homing for Neutrophils. 2019-08-01 10.1016/j.immuni.2019.06.027 2 view
Afik Life Sci Alliance Reconstructing B-cell receptor sequences from short-read single-cell RNA sequencing with BRAPeS. 2019-08-01 10.26508/lsa.201900371 3 view
Senabouth Gigascience ascend: R package for analysis of single-cell RNA-seq data. 2019-08-01 10.1093/gigascience/giz087 11 view
Elyahu Sci Adv Aging promotes reorganization of the CD4 T cell landscape toward extreme regulatory and effector phenotypes. 2019-08-01 10.1126/sciadv.aaw8330 view
Zhang PLoS ONE Transcriptomic profile of early zebrafish PGCs by single cell sequencing. 2019-08-01 10.1371/journal.pone.0220364 view
Bageritz Nat. Methods Gene expression atlas of a developing tissue by single cell expression correlation analysis. 2019-08-01 10.1038/s41592-019-0492-x 13 view
Carter Front Immunol Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity. 2019-08-01 10.3389/fimmu.2019.01516 5 view
Zhou Cancer Cell Int. Characteristics of a novel cell line ZJU-0430 established from human gallbladder carcinoma. 2019-08-01 10.1186/s12935-019-0911-1 view
Kaplan Invest. Ophthalmol. Vis. Sci. Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population. 2019-08-01 10.1167/iovs.19-27656 view
Belle Cancer Discov A Single-Cell Window into Pancreas Cancer Fibroblast Heterogeneity. 2019-08-01 10.1158/2159-8290.CD-19-0576 view
Woo Life Sci Alliance De novo prediction of cell-type complexity in single-cell RNA-seq and tumor microenvironments. 2019-08-01 10.26508/lsa.201900443 1 view
Sharma Immunometabolism Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity. 2019-08-01 10.20900/immunometab20190010 5 view
Chen Commun Biol Single-cell landscape in mammary epithelium reveals bipotent-like cells associated with breast cancer risk and outcome. 2019-08-01 10.1038/s42003-019-0554-8 4 view
Zhang Curr Opin Toxicol Embracing Systems Toxicology at Single-Cell Resolution. 2019-08-01 10.1016/j.cotox.2019.04.003 view
Mercatelli Front Genet Pan-Cancer and Single-Cell Modeling of Genomic Alterations Through Gene Expression. 2019-08-01 10.3389/fgene.2019.00671 view
Dai Medicine (Baltimore) Single-cell transcriptional profiling reveals the heterogenicity in colorectal cancer. 2019-08-01 10.1097/MD.0000000000016916 2 view
Tang Cell Biosci The single-cell sequencing: new developments and medical applications. 2019-08-01 10.1186/s13578-019-0314-y 15 view
Li Front Endocrinol (Lausanne) Growth Hormone Promotes in vitro Maturation of Human Oocytes. 2019-08-01 10.3389/fendo.2019.00485 view
Weinstock Immunometabolism Single-Cell RNA Sequencing of Visceral Adipose Tissue Leukocytes Reveals that Caloric Restriction Following Obesity Promotes the Accumulation of a Distinct Macrophage Population with Features of Phagocytic Cells. 2019-08-01 10.20900/immunometab20190008 10 view
Oliverio Front Pediatr Evolving Clinical Applications of Tissue Transcriptomics in Kidney Disease. 2019-08-01 10.3389/fped.2019.00306 view
von Maydell J. Neurophysiol. The interplay between microglial states and major risk factors in Alzheimer's disease through the eyes of single-cell RNA-sequencing: beyond black and white. 2019-07-31 10.1152/jn.00395.2019 view
Liu Cell Rep Single-Cell RNA-Seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells. 2019-07-30 10.1016/j.celrep.2019.06.092 11 view
Gawel Genome Med A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases. 2019-07-30 10.1186/s13073-019-0657-3 view
Wirka Nat. Med. Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. 2019-07-29 10.1038/s41591-019-0512-5 2 view
Ma Bioinformatics ACTINN: Automated Identification of Cell Types in Single Cell RNA Sequencing. 2019-07-29 10.1093/bioinformatics/btz592 1 view
Xu IEEE/ACM Trans Comput Biol Bioinform A Gene Rank Based Approach for Single Cell Similarity Assessment and Clustering. 2019-07-29 10.1109/TCBB.2019.2931582 2 view
Van Kuijk Cardiovasc. Res. Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single cell sequencing. 2019-07-27 10.1093/cvr/cvz185 view
Segal Nat Commun Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors. 2019-07-26 10.1038/s41467-019-11266-x 25 view
Gu Arterioscler. Thromb. Vasc. Biol. Single-Cell RNA-Sequencing and Metabolomics Analyses Reveal the Contribution of Perivascular Adipose Tissue Stem Cells to Vascular Remodeling. 2019-07-25 10.1161/ATVBAHA.119.312732 8 view
Liu Arterioscler. Thromb. Vasc. Biol. Smooth Muscle Cell Phenotypic Diversity. 2019-07-25 10.1161/ATVBAHA.119.312131 9 view
Yang BMC Genomics Single-cell RNA-seq of esophageal squamous cell carcinoma cell line with fractionated irradiation reveals radioresistant gene expression patterns. 2019-07-25 10.1186/s12864-019-5970-0 view
Halbritter Cancer Discov Epigenomics and Single-cell Sequencing Define a Developmental Hierarchy in Langerhans Cell Histiocytosis. 2019-07-25 10.1158/2159-8290.CD-19-0138 view
Maroni Int J Mol Sci The Role of Prep1 in the Regulation of Mesenchymal Stromal Cells. 2019-07-25 10.3390/ijms20153639 view
Nash Dis Model Mech Genome-wide analysis of androgen receptor binding and transcriptomic analysis in mesenchymal subsets during prostate development. 2019-07-25 10.1242/dmm.039297 view
Cembrowski J. Neurosci. Methods Single-cell transcriptomics as a framework and roadmap for understanding the brain. 2019-07-25 10.1016/j.jneumeth.2019.108353 5 view
Zhang Sci Data Deep single-cell RNA sequencing data of individual T cells from treatment-naïve colorectal cancer patients. 2019-07-24 10.1038/s41597-019-0131-5 2 view
de Soysa Nature Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects. 2019-07-24 10.1038/s41586-019-1414-x view
Hovestadt Nature Resolving medulloblastoma cellular architecture by single-cell genomics. 2019-07-24 10.1038/s41586-019-1434-6 38 view
Hosein JCI Insight Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution. 2019-07-23 10.1172/jci.insight.129212 11 view
Davis-Marcisak Cancer Res. Differential variation analysis enables detection of tumor heterogeneity using single-cell RNA-sequencing data. 2019-07-23 10.1158/0008-5472.CAN-18-3882 view
Wohnhaas Sci Rep DMSO cryopreservation is the method of choice to preserve cells for droplet-based single-cell RNA sequencing. 2019-07-23 10.1038/s41598-019-46932-z 4 view
Bossel Ben-Moshe Nat Commun Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells. 2019-07-22 10.1038/s41467-019-11257-y view
Kim Brain Res. Non-Cell Autonomous Mechanism of Parkinson's Disease Pathology Caused by G2019S LRRK2 Mutation in Ashkenazi Jewish Patient: Single Cell Analysis. 2019-07-19 10.1016/j.brainres.2019.146342 view
Yu BMC Cancer Estimation of immune cell content in tumor using single-cell RNA-seq reference data. 2019-07-19 10.1186/s12885-019-5927-3 3 view
Watanabe Nat Commun Genetic mapping of cell type specificity for complex traits. 2019-07-19 10.1038/s41467-019-11181-1 view
Andriani Sci Rep A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses. 2019-07-19 10.1038/s41598-019-46606-w view
Xin J Vis Exp Single-cell RNA Sequencing and Analysis of Human Pancreatic Islets. 2019-07-18 10.3791/59866 view
Li Development Nkx2-5 defines a subpopulation of pacemaker cells and is essential for the physiological function of the sinoatrial node in mice. 2019-07-18 10.1242/dev.178145 view
Fan Nat Commun Single-cell reconstruction of follicular remodeling in the human adult ovary. 2019-07-18 10.1038/s41467-019-11036-9 8 view
Camargo DNA Res. Uncovering the mouse olfactory long non-coding transcriptome with a novel machine-learning model. 2019-07-18 10.1093/dnares/dsz015 view
Zhang Epigenetics An in vitro attempt at precision toxicology reveals the involvement of DNA methylation alteration in ochratoxin A-induced G0/G1 phase arrest. 2019-07-17 10.1080/15592294.2019.1644878 1 view
Wegmann Genome Biol. CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data. 2019-07-17 10.1186/s13059-019-1739-7 2 view
Hendriks Nat Commun NASC-seq monitors RNA synthesis in single cells. 2019-07-17 10.1038/s41467-019-11028-9 9 view
Tan Cell Syst SingleCellNet: A Computational Tool to Classify Single Cell RNA-Seq Data Across Platforms and Across Species. 2019-07-17 10.1016/j.cels.2019.06.004 6 view
Lv Sci China Life Sci Single-cell RNA sequencing profiling of the effects of aging on alveolar stem cells. 2019-07-17 10.1007/s11427-019-9583-9 view
Kallionpää Diabetes Early Detection of Peripheral Blood Cell Signature in Children Developing Beta-Cell Autoimmunity at a Young Age. 2019-07-16 10.2337/db19-0287 view
Davizon-Castillo Blood TNF-alpha driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. 2019-07-16 10.1182/blood.2019000200 view
Singh Nat Commun High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes. 2019-07-16 10.1038/s41467-019-11049-4 view
Sarkar Bioinformatics Minnow: a principled framework for rapid simulation of dscRNA-seq data at the read level. 2019-07-15 10.1093/bioinformatics/btz351 2 view
Li Bioinformatics A statistical simulator scDesign for rational scRNA-seq experimental design. 2019-07-15 10.1093/bioinformatics/btz321 view
Sturm Bioinformatics Comprehensive evaluation of transcriptome-based cell-type quantification methods for immuno-oncology. 2019-07-15 10.1093/bioinformatics/btz363 view
Climente-González Bioinformatics Block HSIC Lasso: model-free biomarker detection for ultra-high dimensional data. 2019-07-15 10.1093/bioinformatics/btz333 2 view
Stražar Bioinformatics scOrange-a tool for hands-on training of concepts from single-cell data analytics. 2019-07-15 10.1093/bioinformatics/btz348 2 view
Skums Bioinformatics Inference of clonal selection in cancer populations using single-cell sequencing data. 2019-07-15 10.1093/bioinformatics/btz392 view
Barkas Nat. Methods Joint analysis of heterogeneous single-cell RNA-seq dataset collections. 2019-07-15 10.1038/s41592-019-0466-z view
Kovács Int J Mol Sci Unravelling the Role of Trophoblastic-Derived Extracellular Vesicles in Regulatory T Cell Differentiation. 2019-07-14 10.3390/ijms20143457 2 view
Zhang Genes (Basel) SCINA: A Semi-Supervised Subtyping Algorithm of Single Cells and Bulk Samples. 2019-07-12 10.3390/genes10070531 3 view
Tracy BMC Bioinformatics RESCUE: imputing dropout events in single-cell RNA-sequencing data. 2019-07-12 10.1186/s12859-019-2977-0 5 view
Hwang Leuk. Res. Targeted sequencing aids in identifying clonality in chronic myelomonocytic leukemia. 2019-07-12 10.1016/j.leukres.2019.106190 1 view
Pont Nucleic Acids Res. Single-Cell Signature Explorer for comprehensive visualization of single cell signatures across scRNA-seq datasets. 2019-07-11 10.1093/nar/gkz601 18 view
Suvà Mol. Cell Single-Cell RNA Sequencing in Cancer: Lessons Learned and Emerging Challenges. 2019-07-11 10.1016/j.molcel.2019.05.003 39 view
Lam Exp. Cell Res. Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality. 2019-07-11 10.1016/j.yexcr.2019.06.014 6 view
Zhang Circ. Res. Generation of Quiescent Cardiac Fibroblasts from Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis. 2019-07-10 10.1161/CIRCRESAHA.119.315491 2 view
Aizarani Nature A human liver cell atlas reveals heterogeneity and epithelial progenitors. 2019-07-10 10.1038/s41586-019-1373-2 4 view
Erhard Nature scSLAM-seq reveals core features of transcription dynamics in single cells. 2019-07-10 10.1038/s41586-019-1369-y 5 view
Goodyer Circ. Res. Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. 2019-07-09 10.1161/CIRCRESAHA.118.314578 8 view
Wolock Cell Rep Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths. 2019-07-09 10.1016/j.celrep.2019.06.031 11 view
Tang Chest Metabolic Changes in Lymphangioleiomyomatosis Patients Treated with Sirolimus and Hydroxychloroquine. 2019-07-09 10.1016/j.chest.2019.05.038 view
Neftel Cell An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. 2019-07-09 10.1016/j.cell.2019.06.024 79 view
Kotliar Elife Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq. 2019-07-08 10.7554/eLife.43803 20 view
Kinalis BMC Bioinformatics Deconvolution of autoencoders to learn biological regulatory modules from single cell mRNA sequencing data. 2019-07-08 10.1186/s12859-019-2952-9 3 view
Tsoucas Nat Commun Accurate estimation of cell-type composition from gene expression data. 2019-07-05 10.1038/s41467-019-10802-z 5 view
Singh Sci Rep Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis. 2019-07-05 10.1038/s41598-019-45841-5 view
Qi Brief. Bioinformatics Clustering and classification methods for single-cell RNA-sequencing data. 2019-07-04 10.1093/bib/bbz062 view
Herrmann BMC Cancer Infliximab therapy together with tyrosine kinase inhibition targets leukemic stem cells in chronic myeloid leukemia. 2019-07-04 10.1186/s12885-019-5871-2 view
Han Development The lncRNA Hand2os1/Uph locus orchestrates heart development through regulation of precise expression of Hand2. 2019-07-04 10.1242/dev.176198 12 view
Osorio Sci Data Single-cell RNA sequencing of a European and an African lymphoblastoid cell line. 2019-07-04 10.1038/s41597-019-0116-4 1 view
Peng Cell Res. Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma. 2019-07-04 10.1038/s41422-019-0195-y 29 view
Hu PLoS Biol. Dissecting the transcriptome landscape of the human fetal neural retina and retinal pigment epithelium by single-cell RNA-seq analysis. 2019-07-03 10.1371/journal.pbio.3000365 23 view
de Vries Gut High-dimensional cytometric analysis of colorectal cancer reveals novel mediators of antitumour immunity. 2019-07-03 10.1136/gutjnl-2019-318672 view
Darnet Proc. Natl. Acad. Sci. U.S.A. Deep evolutionary origin of limb and fin regeneration. 2019-07-03 10.1073/pnas.1900475116 4 view
Waise Sci Rep An optimised tissue disaggregation and data processing pipeline for characterising fibroblast phenotypes using single-cell RNA sequencing. 2019-07-03 10.1038/s41598-019-45842-4 3 view
Dulken Nature Single-cell analysis reveals T cell infiltration in old neurogenic niches. 2019-07-03 10.1038/s41586-019-1362-5 36 view
Nam Nature Somatic mutations and cell identity linked by Genotyping of Transcriptomes. 2019-07-03 10.1038/s41586-019-1367-0 7 view
Low Cell Stem Cell Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network. 2019-07-02 10.1016/j.stem.2019.06.009 21 view
Brandt Nat Commun Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium. 2019-07-02 10.1038/s41467-019-10954-y 6 view
Fasterius Sci Rep Single-cell RNA-seq variant analysis for exploration of genetic heterogeneity in cancer. 2019-07-02 10.1038/s41598-019-45934-1 2 view
Theil Front Immunol Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys. 2019-07-01 10.3389/fimmu.2019.01340 view
Li Theranostics Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner. 2019-07-01 10.7150/thno.32734 6 view
Greenblatt J. Bone Miner. Res. The Unmixing Problem: A Guide to Applying Single-Cell RNA Sequencing to Bone. 2019-07-01 10.1002/jbmr.3802 view
Zeng Front Genet Single-Cell RNA Sequencing-Based Computational Analysis to Describe Disease Heterogeneity. 2019-07-01 10.3389/fgene.2019.00629 view
Buenaventura Invest. Ophthalmol. Vis. Sci. Identification of Genes With Enriched Expression in Early Developing Mouse Cone Photoreceptors. 2019-07-01 10.1167/iovs.19-26951 1 view
Zhang Stem Cells CD166 engagement augments mouse and human hematopoietic progenitor function via activation of stemness and cell cycle pathways. 2019-07-01 10.1002/stem.3053 view
Domanskyi BMC Bioinformatics Polled Digital Cell Sorter (p-DCS): Automatic identification of hematological cell types from single cell RNA-sequencing clusters. 2019-07-01 10.1186/s12859-019-2951-x view
Zhang Cancer Immunol Res Recharacterizing Tumor-Infiltrating Lymphocytes by Single-Cell RNA Sequencing. 2019-07-01 10.1158/2326-6066.CIR-18-0658 6 view
Janiszewska Nat. Cell Biol. Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments. 2019-07-01 10.1038/s41556-019-0346-x 14 view
Pinto Eur. Heart J. Mapping human pluripotent stem cell-endothelial cell differentiation using scRNA-seq: a step towards therapeutic angiogenesis. 2019-07-01 10.1093/eurheartj/ehz464 view
Tran Dev. Cell In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. 2019-07-01 10.1016/j.devcel.2019.06.001 view
Federico Front Genet Pipeliner: A Nextflow-Based Framework for the Definition of Sequencing Data Processing Pipelines. 2019-07-01 10.3389/fgene.2019.00614 4 view
Mawla Diabetes Navigating the Depths and Avoiding the Shallows of Pancreatic Islet Cell Transcriptomes. 2019-07-01 10.2337/dbi18-0019 view
Chkhaidze PLoS Comput. Biol. Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data. 2019-07-01 10.1371/journal.pcbi.1007243 14 view
Rossi Science Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding. 2019-06-28 10.1126/science.aax1184 6 view
Fang Anal. Chem. Nondestructive identification and accurate isolation of single cells through a chip with Raman optical tweezers. 2019-06-28 10.1021/acs.analchem.9b01604 view
Ma BMC Mol Cell Biol Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose. 2019-06-28 10.1186/s12860-019-0199-y 3 view
Chen J. Am. Soc. Nephrol. Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing Studies. 2019-06-28 10.1681/ASN.2019040415 7 view
Petegrosso Brief. Bioinformatics Machine learning and statistical methods for clustering single-cell RNA-sequencing data. 2019-06-27 10.1093/bib/bbz063 3 view
Tritschler Development Concepts and limitations for learning developmental trajectories from single cell genomics. 2019-06-27 10.1242/dev.170506 6 view
Fang Dev. Biol. Proteomics and single-cell RNA analysis of Akap4-knockout mice model confirm indispensable role of Akap4 in spermatogenesis. 2019-06-27 10.1016/j.ydbio.2019.06.017 10 view
McCracken Eur. Heart J. Transcriptional dynamics of pluripotent stem cell-derived endothelial cell differentiation revealed by single-cell RNA sequencing. 2019-06-26 10.1093/eurheartj/ehz351 view
Law Nat Commun Developmental kinetics and transcriptome dynamics of stem cell specification in the spermatogenic lineage. 2019-06-26 10.1038/s41467-019-10596-0 1 view
Lukacsovich Cell Rep Single-Cell RNA-Seq Reveals Developmental Origins and Ontogenetic Stability of Neurexin Alternative Splicing Profiles. 2019-06-25 10.1016/j.celrep.2019.05.090 view
Campbell Exp. Neurol. Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation. 2019-06-25 10.1016/j.expneurol.2019.112984 3 view
Ren Am. J. Respir. Crit. Care Med. Postnatal Alveologenesis Depends on FOXF1 Signaling in c-KIT+ Endothelial Progenitor Cells. 2019-06-24 10.1164/rccm.201812-2312OC view
Tu Math Biosci Eng Single-cell data-driven mathematical model reveals possible molecular mechanisms of embryonic stem-cell differentiation. 2019-06-24 10.3934/mbe.2019294 view
Patil J. Neuroendocrinol. Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent. 2019-06-24 10.1111/jne.12759 view
Saatcioglu Elife Single-cell sequencing of neonatal uterus reveals an endometrial progenitor indispensable for fertility. 2019-06-24 10.7554/eLife.46349 view
Ponzetta Cell Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors. 2019-06-22 10.1016/j.cell.2019.05.047 15 view
Xiong Circ. Res. Single-Cell Transcriptomics Reveals Chemotaxis Mediated Intra-Organ Crosstalk During Cardiogenesis. 2019-06-21 10.1161/CIRCRESAHA.119.315243 2 view
de Kanter Nucleic Acids Res. CHETAH: a selective, hierarchical cell type identification method for single-cell RNA sequencing. 2019-06-21 10.1093/nar/gkz543 view
Malikic Nat Commun Integrative inference of subclonal tumour evolution from single-cell and bulk sequencing data. 2019-06-21 10.1038/s41467-019-10737-5 15 view
Wang Genes Dev. Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3. 2019-06-20 10.1101/gad.325100.119 view
Morse Eur. Respir. J. Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis. 2019-06-20 10.1183/13993003.02441-2018 3 view
Bell Nat Commun Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia. 2019-06-20 10.1038/s41467-019-10652-9 10 view
Gerovska Sci Rep Computational analysis of single-cell transcriptomics data elucidates the stabilization of Oct4 expression in the E3.25 mouse preimplantation embryo. 2019-06-20 10.1038/s41598-019-45438-y view
Verboom Nucleic Acids Res. SMARTer single cell total RNA sequencing. 2019-06-19 10.1093/nar/gkz535 9 view
Luecken Mol. Syst. Biol. Current best practices in single-cell RNA-seq analysis: a tutorial. 2019-06-19 10.15252/msb.20188746 83 view
Zepp Nat. Rev. Mol. Cell Biol. Cellular crosstalk in the development and regeneration of the respiratory system. 2019-06-19 10.1038/s41580-019-0141-3 view
Joyce J. Clin. Invest. TGFβ signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond Syndrome. 2019-06-18 10.1172/JCI125375 view
Ferrero Hum. Reprod. Single-cell RNA sequencing of oocytes from ovarian endometriosis patients reveals a differential transcriptomic profile associated with lower quality. 2019-06-18 10.1093/humrep/dez053 1 view
Kubli Nat Commun Fcmr regulates mononuclear phagocyte control of anti-tumor immunity. 2019-06-18 10.1038/s41467-019-10619-w view
Tan Cell Rep Single-Cell Transcriptomics Identifies the Adaptation of Scart1+ Vγ6+ T Cells to Skin Residency as Activated Effector Cells. 2019-06-18 10.1016/j.celrep.2019.05.064 view
Vazquez Am. J. Reprod. Immunol. Single-cell technologies in reproductive immunology. 2019-06-17 10.1111/aji.13157 view
Su Proc. Natl. Acad. Sci. U.S.A. α2-Chimaerin is essential for neural stem cell homeostasis in mouse adult neurogenesis. 2019-06-17 10.1073/pnas.1903891116 view
Li Sci Data Multiplex RNA single molecule FISH of inducible mRNAs in single yeast cells. 2019-06-17 10.1038/s41597-019-0106-6 3 view
Fu Nat. Cell Biol. Myc and Dnmt1 impede the pluripotent to totipotent state transition in embryonic stem cells. 2019-06-17 10.1038/s41556-019-0343-0 9 view
Vieira Braga Nat. Med. A cellular census of human lungs identifies novel cell states in health and in asthma. 2019-06-17 10.1038/s41591-019-0468-5 view
Gunner Nat. Neurosci. Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling. 2019-06-17 10.1038/s41593-019-0419-y 3 view
McGinnis Nat. Methods MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices. 2019-06-17 10.1038/s41592-019-0433-8 29 view
Yao Nat. Immunol. Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection. 2019-06-17 10.1038/s41590-019-0403-4 view
Arazi Nat. Immunol. The immune cell landscape in kidneys of patients with lupus nephritis. 2019-06-17 10.1038/s41590-019-0398-x 56 view
Gallegos Dev. Biol. Fibroblast growth factor signaling mediates progenitor cell aggregation and nephron regeneration in the adult zebrafish kidney. 2019-06-17 10.1016/j.ydbio.2019.06.011 2 view
Ye Bioinformatics DECENT: Differential Expression with Capture Efficiency adjustmeNT for single-cell RNA-seq data. 2019-06-14 10.1093/bioinformatics/btz453 12 view
Foster Mol. Reprod. Dev. Single cell RNA-seq in the sea urchin embryo show marked cell-type specificity in the Delta/Notch pathway. 2019-06-14 10.1002/mrd.23181 view
Wang Genome Res. Single-molecule long-read sequencing reveals the chromatin basis of gene expression. 2019-06-14 10.1101/gr.251116.119 5 view
Tibbitt Immunity Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells. 2019-06-14 10.1016/j.immuni.2019.05.014 15 view
Elyada Cancer Discov Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts. 2019-06-13 10.1158/2159-8290.CD-19-0094 43 view
Zhang Nat Commun Simulating multiple faceted variability in single cell RNA sequencing. 2019-06-13 10.1038/s41467-019-10500-w 10 view
Adey Cell Integration of Single-Cell Genomics Datasets. 2019-06-13 10.1016/j.cell.2019.05.034 6 view
Nakamura-Ishizu Cell Beginning of a New Era: Mapping the Bone Marrow Niche. 2019-06-13 10.1016/j.cell.2019.05.042 view
Ren Genomics Proteomics Bioinformatics SSCC: A Novel Computational Framework for Rapid and Accurate Clustering Large-scale Single Cell RNA-seq Data. 2019-06-13 10.1016/j.gpb.2018.10.003 3 view
Rao Compr Physiol Physiology of Electrolyte Transport in the Gut: Implications for Disease. 2019-06-12 10.1002/cphy.c180011 view
Liu Anal. Chem. Bacterial Single Cell Whole Transcriptome Amplification in Microfluidic Platform Shows Putative Gene Expression Heterogeneity. 2019-06-12 10.1021/acs.analchem.8b04773 view
Zhou Cell Stem Cell Single-Cell Transcriptomic Analyses of Cell Fate Transitions during Human Cardiac Reprogramming. 2019-06-12 10.1016/j.stem.2019.05.020 10 view
Ranzoni Essays Biochem. Application of single-cell RNA sequencing methodologies in understanding haematopoiesis and immunology. 2019-06-11 10.1042/EBC20180072 2 view
Lu Nat Rev Cardiol RNA-based diagnostic and therapeutic strategies for cardiovascular disease. 2019-06-11 10.1038/s41569-019-0218-x 22 view
Li Anal. Chem. Detachable Acoustophoretic System for Fluorescence Activated Sorting at Single Droplet Level. 2019-06-10 10.1021/acs.analchem.9b01708 view
Peng BMC Bioinformatics Combining gene ontology with deep neural networks to enhance the clustering of single cell RNA-Seq data. 2019-06-10 10.1186/s12859-019-2769-6 18 view
Ho Cancer Lett. Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer. 2019-06-10 10.1016/j.canlet.2019.06.002 1 view
Seiler Cell Mol Gastroenterol Hepatol Single-Cell Analysis Reveals Regional Reprogramming during Adaptation to Massive Small Bowel Resection in Mice. 2019-06-10 10.1016/j.jcmgh.2019.06.001 4 view
Zhang Nucleic Acids Res. Learning common and specific patterns from data of multiple interrelated biological scenarios with matrix factorization. 2019-06-08 10.1093/nar/gkz488 1 view
Zhang J Ovarian Res Mitochondrial dysfunction and endoplasmic reticulum stress involved in oocyte aging: an analysis using single-cell RNA-sequencing of mouse oocytes. 2019-06-08 10.1186/s13048-019-0529-x 2 view
Hung J. Immunol. Cell-Intrinsic Wnt4 Influences Conventional Dendritic Cell Fate Determination to Suppress Type 2 Immunity. 2019-06-07 10.4049/jimmunol.1900363 3 view
Deyell Semin. Cell Dev. Biol. Large scale control and programming of gene expression using CRISPR. 2019-06-07 10.1016/j.semcdb.2019.05.013 1 view
Abrams BMC Bioinformatics A computational method to aid the design and analysis of single cell RNA-seq experiments for cell type identification. 2019-06-06 10.1186/s12859-019-2817-2 2 view
Todd J Neuroinflammation Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina. 2019-06-06 10.1186/s12974-019-1505-5 2 view
Kolter Immunity A Subset of Skin Macrophages Contributes to the Surveillance and Regeneration of Local Nerves. 2019-06-05 10.1016/j.immuni.2019.05.009 7 view
Velasco Nature Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. 2019-06-05 10.1038/s41586-019-1289-x 21 view
Iacono Genome Biol. Single-cell transcriptomics unveils gene regulatory network plasticity. 2019-06-04 10.1186/s13059-019-1713-4 28 view
Welch Cell Single-Cell Multi-omic Integration Compares and Contrasts Features of Brain Cell Identity. 2019-06-03 10.1016/j.cell.2019.05.006 71 view
Bastidas-Ponce Development Massive single-cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis. 2019-06-03 10.1242/dev.173849 view
Liu Cell Death Dis Dissecting cell diversity and connectivity in skeletal muscle for myogenesis. 2019-06-03 10.1038/s41419-019-1647-5 1 view
Pellin Nat Commun A comprehensive single cell transcriptional landscape of human hematopoietic progenitors. 2019-06-03 10.1038/s41467-019-10291-0 3 view
Yoshimura Kidney Int. Podocyte development, disease, and stem cell research. 2019-06-03 10.1016/j.kint.2019.04.044 1 view
Ji Curr Protoc Mol Biol Single-Cell RNA-seq: Introduction to Bioinformatics Analysis. 2019-06-01 10.1002/cpmb.92 view
Lee Methods Mol. Biol. Cancer Stem Cells: Concepts, Challenges, and Opportunities for Cancer Therapy. 2019-06-01 10.1007/978-1-4939-9524-0_4 view
Diaz-Mejia F1000Res Evaluation of methods to assign cell type labels to cell clusters from single-cell RNA-sequencing data. 2019-06-01 10.12688/f1000research.18490.3 view
El Amrani PeerJ Detection of condition-specific marker genes from RNA-seq data with MGFR. 2019-06-01 10.7717/peerj.6970 view
Der Lupus Sci Med Single-cell RNA sequencing for the study of lupus nephritis. 2019-06-01 10.1136/lupus-2019-000329 2 view
Rhodes Front Immunol Human Dendritic Cell Subsets, Ontogeny, and Impact on HIV Infection. 2019-06-01 10.3389/fimmu.2019.01088 view
Jonasson Front Genet Identification of Breast Cancer Stem Cell Related Genes Using Functional Cellular Assays Combined With Single-Cell RNA Sequencing in MDA-MB-231 Cells. 2019-06-01 10.3389/fgene.2019.00500 view
Guillot Hepatol Commun Liver Macrophages: Old Dogmas and New Insights. 2019-06-01 10.1002/hep4.1356 32 view
Wang Medicine (Baltimore) Single-cell RNA sequencing reveals novel gene expression signatures of trastuzumab treatment in HER2+ breast cancer: A pilot study. 2019-06-01 10.1097/MD.0000000000015872 view
Zhang Endocrinology Regulation of Feeding-Related Behaviors by Arcuate Neuropeptide Y Neurons. 2019-06-01 10.1210/en.2019-00056 4 view
Gao J Zhejiang Univ Sci B Novel insights into cell cycle regulation of cell fate determination. 2019-06-01 10.1631/jzus.B1900197 1 view
Wiedmeier Cancer Treat. Res. Single-Cell Sequencing in Precision Medicine. 2019-06-01 10.1007/978-3-030-16391-4_9 view
Gu Arterioscler. Thromb. Vasc. Biol. Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing. 2019-06-01 10.1161/ATVBAHA.119.312399 23 view
Kalluri Circulation Single Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations. 2019-05-31 10.1161/CIRCULATIONAHA.118.038362 35 view
Addo Eur. J. Immunol. Single-cell transcriptomes of murine bone marrow stromal cells Reveal niche-associated heterogeneity. 2019-05-31 10.1002/eji.201848053 4 view
Sharma Elife Identification of EOMES-expressing spermatogonial stem cells and their regulation by PLZF. 2019-05-31 10.7554/eLife.43352 6 view
Zhao BMC Med Genomics Single-cell RNA sequencing reveals the impact of chromosomal instability on glioblastoma cancer stem cells. 2019-05-31 10.1186/s12920-019-0532-5 1 view
Stuart Cell Comprehensive Integration of Single-Cell Data. 2019-05-30 10.1016/j.cell.2019.05.031 441 view
Du Bioinformatics deconvSeq: Deconvolution of Cell Mixture Distribution in Sequencing Data. 2019-05-30 10.1093/bioinformatics/btz444 3 view
Shainer Curr. Biol. Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System. 2019-05-29 10.1016/j.cub.2019.05.021 2 view
Prior Development Lgr5+ stem/progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool. 2019-05-29 10.1242/dev.174557 view
Li Development Single cell expression analysis reveals anatomical and cell cycle-dependent transcriptional shifts during heart development. 2019-05-29 10.1242/dev.173476 7 view
Tang Stem Cell Reports Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids. 2019-05-29 10.1016/j.stemcr.2019.05.014 view
Baek Cell Rep Molecular Logic of Spinocerebellar Tract Neuron Diversity and Connectivity. 2019-05-28 10.1016/j.celrep.2019.04.113 3 view
Lukowski Cell Rep Single-Cell Transcriptional Profiling of Aortic Endothelium Identifies a Hierarchy from Endovascular Progenitors to Differentiated Cells. 2019-05-28 10.1016/j.celrep.2019.04.102 16 view
Uniken Venema Gastroenterology Reply to: Letter to the Editor: Single-cell RNA Sequencing of T Cells in Crohn's Disease (GASTRO-D-18-02454). 2019-05-28 10.1053/j.gastro.2019.05.045 view
Tian Nat. Methods Benchmarking single cell RNA-sequencing analysis pipelines using mixture control experiments. 2019-05-27 10.1038/s41592-019-0425-8 33 view
Bhardwaj Bioinformatics snakePipes: facilitating flexible, scalable and integrative epigenomic analysis. 2019-05-27 10.1093/bioinformatics/btz436 1 view
Hie Cell Syst Geometric Sketching Compactly Summarizes the Single-Cell Transcriptomic Landscape. 2019-05-27 10.1016/j.cels.2019.05.003 11 view
Zhu Sci Rep Exploratory Gene Ontology Analysis with Interactive Visualization. 2019-05-24 10.1038/s41598-019-42178-x view
Del Fresno Trends Immunol. cDC1s: New Orchestrators of Tissue Innate Immunity. 2019-05-24 10.1016/ view
Krenkel Cells Single Cell RNA Sequencing Identifies Subsets of Hepatic Stellate Cells and Myofibroblasts in Liver Fibrosis. 2019-05-24 10.3390/cells8050503 23 view
Zhang Bioinformatics EnImpute: imputing dropout events in single cell RNA sequencing data via ensemble learning. 2019-05-24 10.1093/bioinformatics/btz435 view
Farber Genome Med Dissecting lung development and fibrosis at single-cell resolution. 2019-05-24 10.1186/s13073-019-0645-7 3 view
Stopka J. Theor. Biol. A stochastic model of adult neurogenesis coupling cell cycle progression and differentiation. 2019-05-22 10.1016/j.jtbi.2019.05.014 view
Wang Neuron Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area. 2019-05-22 10.1016/j.neuron.2019.04.035 1 view
Tang Nucleic Acids Res. GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis. 2019-05-22 10.1093/nar/gkz430 43 view
Bai Bioinformatics Statistical test of structured continuous trees based on discordance matrix. 2019-05-22 10.1093/bioinformatics/btz425 view
Feregrino BMC Genomics A single-cell transcriptomic atlas of the developing chicken limb. 2019-05-22 10.1186/s12864-019-5802-2 4 view
Yuan Cell Commun. Signal Systematic expression analysis of ligand-receptor pairs reveals important cell-to-cell interactions inside glioma. 2019-05-22 10.1186/s12964-019-0363-1 view
Li Development The molecular anatomy of mammalian upper lip and primary palate fusion at single cell resolution. 2019-05-22 10.1242/dev.174888 5 view
Pizzolato Proc. Natl. Acad. Sci. U.S.A. Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes. 2019-05-22 10.1073/pnas.1818488116 2 view
Stein-O'Brien Cell Syst Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species. 2019-05-22 10.1016/j.cels.2019.04.004 view
Su Clin. Cancer Res. Inferring the Evolution and Progression of Small-Cell Lung Cancer by Single-Cell Sequencing of Circulating Tumor Cells. 2019-05-21 10.1158/1078-0432.CCR-18-3571 8 view
Sharon Cell Rep Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. 2019-05-21 10.1016/j.celrep.2019.04.083 25 view
Kupari Cell Rep An Atlas of Vagal Sensory Neurons and Their Molecular Specialization. 2019-05-21 10.1016/j.celrep.2019.04.096 48 view
Duan Nat Commun Model-based understanding of single-cell CRISPR screening. 2019-05-20 10.1038/s41467-019-10216-x 1 view
Der Nat. Immunol. Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. 2019-05-20 10.1038/s41590-019-0386-1 35 view
Aztekin Science Identification of a regeneration-organizing cell in the Xenopus tail. 2019-05-17 10.1126/science.aav9996 25 view
Zhou Am J Sports Med Single-Cell Profiles and Clinically Useful Properties of Human Mesenchymal Stem Cells of Adipose and Bone Marrow Origin. 2019-05-17 10.1177/0363546519848678 view
Keren-Shaul Nat Protoc MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing. 2019-05-17 10.1038/s41596-019-0164-4 view
Tawil Semin. Thromb. Hemost. Oncogenes and Clotting Factors: The Emerging Role of Tumor Cell Genome and Epigenome in Cancer-Associated Thrombosis. 2019-05-16 10.1055/s-0039-1687891 view
Drayman Elife HSV-1 single cell analysis reveals anti-viral and developmental programs activation in distinct sub-populations. 2019-05-15 10.7554/eLife.46339 view
Cheng Nat Commun Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells. 2019-05-15 10.1038/s41467-019-10122-2 37 view
Ellis Nature Distinct modes of cell competition shape mammalian tissue morphogenesis. 2019-05-15 10.1038/s41586-019-1199-y view
Ayturk Curr Osteoporos Rep RNA-seq in Skeletal Biology. 2019-05-15 10.1007/s11914-019-00517-x 2 view
Zhou Mol. Reprod. Dev. Single-cell RNA-seq reveals distinct dynamic behavior of sex chromosomes during early human embryogenesis. 2019-05-15 10.1002/mrd.23162 4 view
Russo Neurobiol. Dis. Transcriptase analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils. 2019-05-15 10.1016/j.nbd.2019.05.012 view
Pan Aging Cell Perivascular adipose tissue-derived stromal cells contribute to vascular remodeling during aging. 2019-05-14 10.1111/acel.12969 3 view
Shulse Cell Rep High-Throughput Single-Cell Transcriptome Profiling of Plant Cell Types. 2019-05-14 10.1016/j.celrep.2019.04.054 37 view
Adelman Cancer Discov Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia. 2019-05-13 10.1158/2159-8290.CD-18-1474 18 view
Kudo Proc. Natl. Acad. Sci. U.S.A. Low ambient humidity impairs barrier function and innate resistance against influenza infection. 2019-05-13 10.1073/pnas.1902840116 10 view
Chan Nature Molecular recording of mammalian embryogenesis. 2019-05-13 10.1038/s41586-019-1184-5 15 view
Suzuki Biol. Reprod. What has single-cell RNA-seq taught us about mammalian spermatogenesis? 2019-05-11 10.1093/biolre/ioz088 4 view
Telley Science Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. 2019-05-10 10.1126/science.aav2522 view
Krenkel Gut Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis. 2019-05-10 10.1136/gutjnl-2019-318382 9 view
Moreno-Villanueva Int J Mol Sci Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation Exposure. 2019-05-10 10.3390/ijms20092316 view
Baryawno Cell A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia. 2019-05-09 10.1016/j.cell.2019.04.040 19 view
Karlsen Cartilage Single-Cell RNA Sequencing of In Vitro Expanded Chondrocytes: MSC-Like Cells With No Evidence of Distinct Subsets. 2019-05-09 10.1177/1947603519847746 view
Kim Proc. Natl. Acad. Sci. U.S.A. Generation, transcriptome profiling, and functional validation of cone-rich human retinal organoids. 2019-05-09 10.1073/pnas.1901572116 5 view
Melsted Bioinformatics The Barcode, UMI, Set format and BUStools. 2019-05-09 10.1093/bioinformatics/btz279 11 view
Clark Neuron Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification. 2019-05-08 10.1016/j.neuron.2019.04.010 view
Ye BMC Genomics scNPF: an integrative framework assisted by network propagation and network fusion for preprocessing of single-cell RNA-seq data. 2019-05-08 10.1186/s12864-019-5747-5 1 view
Russell J. Virol. Single-cell virus sequencing of influenza infections that trigger innate immunity. 2019-05-08 10.1128/JVI.00500-19 24 view
Kuo Sci Transl Med HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness. 2019-05-08 10.1126/scitranslmed.aau8587 view
Ma Proc. Natl. Acad. Sci. U.S.A. Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells. 2019-05-08 10.1073/pnas.1903550116 view
Zhang Cell Rep Dissecting the Single-Cell Transcriptome Network Underlying Gastric Premalignant Lesions and Early Gastric Cancer. 2019-05-07 10.1016/j.celrep.2019.04.052 22 view
Voigt Exp. Eye Res. Molecular characterization of foveal versus peripheral human retina by single-cell RNA sequencing. 2019-05-07 10.1016/j.exer.2019.05.001 25 view
Planas-Paz Cell Stem Cell YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury. 2019-05-07 10.1016/j.stem.2019.04.005 24 view
Rodriguez-Villalon Curr. Opin. Plant Biol. Single cell RNA sequencing and its promise in reconstructing plant vascular cell lineages. 2019-05-06 10.1016/j.pbi.2019.04.002 view
Peng Genome Biol. SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data. 2019-05-06 10.1186/s13059-019-1681-8 15 view
Newman Nat. Biotechnol. Determining cell type abundance and expression from bulk tissues with digital cytometry. 2019-05-06 10.1038/s41587-019-0114-2 55 view
Hie Nat. Biotechnol. Efficient integration of heterogeneous single-cell transcriptomes using Scanorama. 2019-05-06 10.1038/s41587-019-0113-3 47 view
Van Hove Nat. Neurosci. A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. 2019-05-06 10.1038/s41593-019-0393-4 view
Zhang Nat. Immunol. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. 2019-05-06 10.1038/s41590-019-0378-1 66 view
Chen Adv Sci (Weinh) Multiplexed, Sequential Secretion Analysis of the Same Single Cells Reveals Distinct Effector Response Dynamics Dependent on the Initial Basal State. 2019-05-03 10.1002/advs.201801361 view
Poon Oncotarget Differential microglia and macrophage profiles in human IDH-mutant and -wild type glioblastoma. 2019-05-03 10.18632/oncotarget.26863 10 view
Spallanzani Sci Immunol Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors. 2019-05-03 10.1126/sciimmunol.aaw3658 view
Wong Arterioscler. Thromb. Vasc. Biol. Genetic Insights Into Smooth Muscle Cell Contributions to Coronary Artery Disease. 2019-05-02 10.1161/ATVBAHA.119.312141 view
Wang BMC Bioinformatics scruff: an R/Bioconductor package for preprocessing single-cell RNA-sequencing data. 2019-05-02 10.1186/s12859-019-2797-2 2 view
Bonaguidi Cell Stem Cell Evaluation of Weng et al.: Leveraging Cell Type Correlations and Single-Cell Bioinformatics to Identify Progenitor Diversity and Lineage. 2019-05-02 10.1016/j.stem.2019.04.011 view
Lamarche Can J Kidney Health Dis Infectious Disease Risk in Dialysis Patients: A Transdisciplinary Approach. 2019-05-01 10.1177/2054358119839080 view
Sharma Mol Cell Oncol Tracking tumor evolution one-cell-at-a-time. 2019-05-01 10.1080/23723556.2019.1590089 3 view
Want Oncoimmunology Neoantigens retention in patient derived xenograft models mediates autologous T cells activation in ovarian cancer. 2019-05-01 10.1080/2162402X.2019.1586042 2 view
Penter Oncoimmunology Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer. 2019-05-01 10.1080/2162402X.2019.1586409 2 view
Curato Front Immunol DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node. 2019-05-01 10.3389/fimmu.2019.00863 view
Wang BMC Bioinformatics Generalized gene co-expression analysis via subspace clustering using low-rank representation. 2019-05-01 10.1186/s12859-019-2733-5 1 view
Chen BMC Bioinformatics VPAC: Variational projection for accurate clustering of single-cell transcriptomic data. 2019-05-01 10.1186/s12859-019-2742-4 1 view
Liu Biomicrofluidics Whole genome amplification of single epithelial cells dissociated from snap-frozen tissue samples in microfluidic platform. 2019-05-01 10.1063/1.5090235 view
Pepe-Mooney Cell Stem Cell Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. 2019-05-01 10.1016/j.stem.2019.04.004 43 view
Luo Mediators Inflamm. Epigenetic Regulation of IL-17-Induced Chemokines in Lung Epithelial Cells. 2019-05-01 10.1155/2019/9050965 1 view
Tang Front Genet High-Order Correlation Integration for Single-Cell or Bulk RNA-seq Data Analysis. 2019-05-01 10.3389/fgene.2019.00371 3 view
Fang J. Clin. Endocrinol. Metab. Insights Into Local Orbital Immunity: Evidence for the Involvement of the Th17 Cell Pathway in Thyroid-Associated Ophthalmopathy. 2019-05-01 10.1210/jc.2018-01626 3 view
Vladoiu Nature Childhood cerebellar tumours mirror conserved fetal transcriptional programs. 2019-05-01 10.1038/s41586-019-1158-7 view
Gogolewski J. Comput. Biol. Truncated Robust Principal Component Analysis and Noise Reduction for Single Cell RNA Sequencing Data. 2019-05-01 10.1089/cmb.2018.0255 1 view
Kim PLoS ONE Alternative polyadenylation of single cells delineates cell types and serves as a prognostic marker in early stage breast cancer. 2019-05-01 10.1371/journal.pone.0217196 view
Zhao Gigascience Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood. 2019-05-01 10.1093/gigascience/giz047 view
Anstine J Cancer Metastasis Treat A new view of the mammary epithelial hierarchy and its implications for breast cancer initiation and metastasis. 2019-05-01 10.20517/2394-4722.2019.24 view
Shin Sci Adv Multiplexed single-cell RNA-seq via transient barcoding for simultaneous expression profiling of various drug perturbations. 2019-05-01 10.1126/sciadv.aav2249 3 view
Salomonis Methods Mol. Biol. Investigating Cell Fate Decisions with ICGS Analysis of Single Cells. 2019-05-01 10.1007/978-1-4939-9224-9_12 view
Sagar Methods Mol. Biol. Lineage Inference and Stem Cell Identity Prediction Using Single-Cell RNA-Sequencing Data. 2019-05-01 10.1007/978-1-4939-9224-9_13 view
Wu Front Genet NormExpression: An R Package to Normalize Gene Expression Data Using Evaluated Methods. 2019-05-01 10.3389/fgene.2019.00400 2 view
Lin Bioinformatics Continuous State HMMs for Modeling Time Series Single Cell RNA-Seq Data. 2019-04-30 10.1093/bioinformatics/btz296 6 view
Johnson Bioinformatics LAmbDA: Label Ambiguous Domain Adaptation Dataset Integration Reduces Batch Effects and Improves Subtype Detection. 2019-04-30 10.1093/bioinformatics/btz295 3 view
Lossos Cancer Discov Mechanisms of lymphoma clearance induced by high-dose alkylating agents. 2019-04-30 10.1158/2159-8290.CD-18-1393 7 view
Xue Cell Rep A 3D Atlas of Hematopoietic Stem and Progenitor Cell Expansion by Multi-dimensional RNA-Seq Analysis. 2019-04-30 10.1016/j.celrep.2019.04.030 2 view
Song Cancer Med Dissecting intratumoral myeloid cell plasticity by single cell RNA-seq. 2019-04-29 10.1002/cam4.2113 3 view
Lin Proc. Natl. Acad. Sci. U.S.A. scMerge leverages factor analysis, stable expression, and pseudoreplication to merge multiple single-cell RNA-seq datasets. 2019-04-26 10.1073/pnas.1820006116 view
Neri Nat Commun Human pre-valvular endocardial cells derived from pluripotent stem cells recapitulate cardiac pathophysiological valvulogenesis. 2019-04-26 10.1038/s41467-019-09459-5 10 view
Hou Bioinformatics scMatch: a single-cell gene expression profile annotation tool using reference datasets. 2019-04-26 10.1093/bioinformatics/btz292 19 view
Vu Bioinformatics Cell-level somatic mutation detection from single-cell RNA-sequencing. 2019-04-26 10.1093/bioinformatics/btz288 2 view
Merrick Science Identification of a mesenchymal progenitor cell hierarchy in adipose tissue. 2019-04-26 10.1126/science.aav2501 9 view
Sarntivijai BMC Bioinformatics Cells in ExperimentaL Life Sciences (CELLS-2018): capturing the knowledge of normal and diseased cells with ontologies. 2019-04-25 10.1186/s12859-019-2721-9 view
Ramazzotti BMC Bioinformatics Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data. 2019-04-25 10.1186/s12859-019-2795-4 view
Liu J Transl Med Journal of Translational Medicine advances in Translational Genomics and Genetics Era. 2019-04-25 10.1186/s12967-019-1874-7 view
Ludwig Eur. J. Immunol. High-throughput single-cell sequencing of paired TCRα and TCRβ genes for the direct expression-cloning and functional analysis of murine T cell receptors. 2019-04-24 10.1002/eji.201848030 view
Ayyaz Nature Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell. 2019-04-24 10.1038/s41586-019-1154-y 10 view
Cole Cell Syst Performance Assessment and Selection of Normalization Procedures for Single-Cell RNA-Seq. 2019-04-24 10.1016/j.cels.2019.03.010 32 view
Cosacak Cell Rep Single-Cell Transcriptomics Analyses of Neural Stem Cell Heterogeneity and Contextual Plasticity in a Zebrafish Brain Model of Amyloid Toxicity. 2019-04-23 10.1016/j.celrep.2019.03.090 6 view
Miao Cell Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells. 2019-04-22 10.1016/j.cell.2019.03.025 33 view
Sekula Biometrics Detection of differentially expressed genes in discrete single-cell RNA sequencing data using a hurdle model with correlated random effects. 2019-04-22 10.1111/biom.13074 3 view
Gaydosik Clin. Cancer Res. Single-cell lymphocyte heterogeneity in advanced Cutaneous T-Cell Lymphoma skin tumors. 2019-04-22 10.1158/1078-0432.CCR-19-0148 view
Lu Int J Mol Sci ChimeraMiner: An Improved Chimeric Read Detection Pipeline and Its Application in Single Cell Sequencing. 2019-04-21 10.3390/ijms20081953 view
Zhang Brief. Bioinformatics Single-cell transcriptome-based multilayer network biomarker for predicting prognosis and therapeutic response of gliomas. 2019-04-18 10.1093/bib/bbz040 5 view
Salomon Lab Chip Droplet-based single cell RNAseq tools: a practical guide. 2019-04-18 10.1039/c8lc01239c 2 view
Zhang Mol Plant A Single-Cell RNA Sequencing Profiles the Developmental Landscape of Arabidopsis Root. 2019-04-17 10.1016/j.molp.2019.04.004 view
Brioschi Trends Neurosci. Fifty Shades of Microglia. 2019-04-17 10.1016/j.tins.2019.03.010 view
Wester Neuron Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner. 2019-04-16 10.1016/j.neuron.2019.03.036 9 view
Li JCI Insight Single cell transcriptomics based-MacSpectrum reveals novel macrophage activation signatures in diseases. 2019-04-16 10.1172/jci.insight.126453 view
Huang Proc. Natl. Acad. Sci. U.S.A. Select sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansion. 2019-04-16 10.1073/pnas.1902649116 view
Genga Cell Rep Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. 2019-04-16 10.1016/j.celrep.2019.03.076 22 view
Heng Proc. Natl. Acad. Sci. U.S.A. Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution. 2019-04-15 10.1073/pnas.1821122116 8 view
Makino Sci Rep Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression. 2019-04-15 10.1038/s41598-019-42578-z 2 view
Salamanca Glia MIC-MAC: An automated pipeline for high-throughput characterization and classification of three-dimensional microglia morphologies in mouse and human postmortem brain samples. 2019-04-14 10.1002/glia.23623 3 view
Zhou Am. J. Respir. Cell Mol. Biol. Beyond Fibroblast Heterogeneity: What Single-Cell RNA-Seq Tells Us. 2019-04-12 10.1165/rcmb.2019-0120ED view
Dell'Orso Development Single cell analysis of adult mouse skeletal muscle stem cells in homeostatic and regenerative conditions. 2019-04-11 10.1242/dev.174177 view
Miermont Development The fate of cells undergoing spontaneous DNA damage during development. 2019-04-11 10.1242/dev.174268 3 view
Du Gastroenterology Single-cell RNA Sequencing of T Cells in Crohn's Disease. 2019-04-11 10.1053/j.gastro.2018.12.049 view
Kulkarni Curr. Opin. Biotechnol. Beyond bulk: a review of single cell transcriptomics methodologies and applications. 2019-04-09 10.1016/j.copbio.2019.03.001 1 view
Natarajan Genome Biol. Comparative analysis of sequencing technologies for single-cell transcriptomics. 2019-04-09 10.1186/s13059-019-1676-5 view
Sun Nat Commun A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies. 2019-04-09 10.1038/s41467-019-09639-3 9 view
Yue Aging Cell Cell-type-specific role of lamin-B1 in thymus development and its inflammation-driven reduction in thymus aging. 2019-04-09 10.1111/acel.12952 5 view
Sekiguchi Curr Protoc Cell Biol Preparation of Cells from Embryonic Organs for Single-Cell RNA Sequencing. 2019-04-08 10.1002/cpcb.86 1 view
Wen J. Clin. Invest. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. 2019-04-08 10.1172/JCI125917 14 view
Eckalbar J. Clin. Invest. Singling out Th2 cells in eosinophilic esophagitis. 2019-04-08 10.1172/JCI128479 1 view
Skinnider Nat. Methods Evaluating measures of association for single-cell transcriptomics. 2019-04-08 10.1038/s41592-019-0372-4 17 view
Zilionis Immunity Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species. 2019-04-05 10.1016/j.immuni.2019.03.009 89 view
Nelms Science Defining the developmental program leading to meiosis in maize. 2019-04-05 10.1126/science.aav6428 20 view
Kania Nat Rev Rheumatol Involvement of the myeloid cell compartment in fibrogenesis and systemic sclerosis. 2019-04-05 10.1038/s41584-019-0212-z view
Sun BMC Syst Biol A fast and efficient count-based matrix factorization method for detecting cell types from single-cell RNAseq data. 2019-04-05 10.1186/s12918-019-0699-6 5 view
Zimmerman J. Am. Soc. Nephrol. Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species. 2019-04-04 10.1681/ASN.2018090931 3 view
Clatworthy J. Am. Soc. Nephrol. How to Find a Resident Kidney Macrophage: the Single-Cell Sequencing Solution. 2019-04-04 10.1681/ASN.2019030245 view
Liu Bioinformatics scRNAss: a single-cell RNA-seq assembler via imputing dropouts and combing junctions. 2019-04-04 10.1093/bioinformatics/btz240 view
An BMC Genomics TSEE: an elastic embedding method to visualize the dynamic gene expression patterns of time series single-cell RNA sequencing data. 2019-04-04 10.1186/s12864-019-5477-8 view
Hinterndorfer Curr. Opin. Genet. Dev. Functional-genetic approaches to understanding drug response and resistance. 2019-04-02 10.1016/j.gde.2019.03.003 view
Mamanova Methods Mol. Biol. Setting Up a Single-Cell Genomic Laboratory. 2019-04-01 10.1007/978-1-4939-9240-9_1 view
Vieira Braga Methods Mol. Biol. Tissue Handling and Dissociation for Single-Cell RNA-Seq. 2019-04-01 10.1007/978-1-4939-9240-9_2 view
Picelli Methods Mol. Biol. Full-Length Single-Cell RNA Sequencing with Smart-seq2. 2019-04-01 10.1007/978-1-4939-9240-9_3 view
Yanai Methods Mol. Biol. CEL-Seq2-Single-Cell RNA Sequencing by Multiplexed Linear Amplification. 2019-04-01 10.1007/978-1-4939-9240-9_4 1 view
Sheng Methods Mol. Biol. Single-Cell RNA-Seq by Multiple Annealing and Tailing-Based Quantitative Single-Cell RNA-Seq (MATQ-Seq). 2019-04-01 10.1007/978-1-4939-9240-9_5 1 view
Bageritz Methods Mol. Biol. Single-Cell RNA Sequencing with Drop-Seq. 2019-04-01 10.1007/978-1-4939-9240-9_6 2 view
Aicher Methods Mol. Biol. Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing. 2019-04-01 10.1007/978-1-4939-9240-9_8 4 view
Natarajan Methods Mol. Biol. Single-Cell Tagged Reverse Transcription (STRT-Seq). 2019-04-01 10.1007/978-1-4939-9240-9_9 view
Khan Methods Mol. Biol. Single-Cell RNA-Sequencing of Peripheral Blood Mononuclear Cells with ddSEQ. 2019-04-01 10.1007/978-1-4939-9240-9_10 3 view
Li Methods Mol. Biol. Targeted TCR Amplification from Single-Cell cDNA Libraries. 2019-04-01 10.1007/978-1-4939-9240-9_13 view
Henriksson Methods Mol. Biol. CRISPR Screening in Single Cells. 2019-04-01 10.1007/978-1-4939-9240-9_23 view
Alessandrì Methods Mol. Biol. Differential Expression Analysis in Single-Cell Transcriptomics. 2019-04-01 10.1007/978-1-4939-9240-9_25 view
Baßler Methods Mol. Biol. A Bioinformatic Toolkit for Single-Cell mRNA Analysis. 2019-04-01 10.1007/978-1-4939-9240-9_26 view
Huss Front Cell Dev Biol Avian Primordial Germ Cells Contribute to and Interact With the Extracellular Matrix During Early Migration. 2019-04-01 10.3389/fcell.2019.00035 view
Hamanaka Hum. Mol. Genet. MYRF haploinsufficiency causes 46,XY and 46,XX disorders of sex development: bioinformatics consideration. 2019-04-01 10.1093/hmg/ddz066 view
Wang Chin. J. Cancer Res. Extensive exploration of T cell heterogeneity in cancers by single cell sequencing. 2019-04-01 10.21147/j.issn.1000-9604.2019.02.15 view
Ben-Moshe Nat Rev Gastroenterol Hepatol Spatial heterogeneity in the mammalian liver. 2019-04-01 10.1038/s41575-019-0134-x 18 view
Fischer Nat. Biotechnol. Inferring population dynamics from single-cell RNA-sequencing time series data. 2019-04-01 10.1038/s41587-019-0088-0 13 view
Ferrall-Fairbanks JCO Clin Cancer Inform Leveraging Single-Cell RNA Sequencing Experiments to Model Intratumor Heterogeneity. 2019-04-01 10.1200/CCI.18.00074 view
Yoo Front Neurosci Tanycyte-Independent Control of Hypothalamic Leptin Signaling. 2019-04-01 10.3389/fnins.2019.00240 view
Rodriguez-Zhurbenko Front Immunol Human B-1 Cells and B-1 Cell Antibodies Change With Advancing Age. 2019-04-01 10.3389/fimmu.2019.00483 5 view
Oulhen Methods Cell Biol. Identifying gene expression from single cells to single genes. 2019-04-01 10.1016/bs.mcb.2018.11.018 1 view
Sarkar PLoS Genet. Discovery and characterization of variance QTLs in human induced pluripotent stem cells. 2019-04-01 10.1371/journal.pgen.1008045 16 view
Rinschen Kidney Int. A knowledge-guided kidney cell census-reconciling bulk omics with cellular heterogeneity? 2019-04-01 10.1016/j.kint.2018.12.016 view
Wick Epilepsy Curr Seizing Sequencing Data to Consider Cell and Circuit Complexity. 2019-04-01 10.1177/1535759719835658 1 view
Birbrair Adv. Exp. Med. Biol. Stem Cells Heterogeneity. 2019-04-01 10.1007/978-3-030-11096-3_1 4 view
Sasagawa Adv. Exp. Med. Biol. Strategies for Converting RNA to Amplifiable cDNA for Single-Cell RNA Sequencing Methods. 2019-04-01 10.1007/978-981-13-6037-4_1 1 view
Kashima Adv. Exp. Med. Biol. An Informative Approach to Single-Cell Sequencing Analysis. 2019-04-01 10.1007/978-981-13-6037-4_6 view
Peters PLoS ONE Single cell RNA sequencing reveals regional heterogeneity of hepatobiliary innate lymphoid cells in a tissue-enriched fashion. 2019-04-01 10.1371/journal.pone.0215481 2 view
Kong PLoS ONE Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data. 2019-04-01 10.1371/journal.pone.0215987 1 view
Malone Transplantation Single Cell Transcriptomics and Solid Organ Transplantation. 2019-04-01 10.1097/TP.0000000000002725 2 view
Chen Front Genet Single-Cell RNA-Seq Technologies and Related Computational Data Analysis. 2019-04-01 10.3389/fgene.2019.00317 60 view
Rodriques Science Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution. 2019-03-29 10.1126/science.aaw1219 view
Wang Nucleic Acids Res. Cell lineage and communication network inference via optimization for single-cell transcriptomics. 2019-03-29 10.1093/nar/gkz204 7 view
Jean-Baptiste Plant Cell Dynamics of gene expression in single root cells of A. thaliana. 2019-03-28 10.1105/tpc.18.00785 view
Everman J. Allergy Clin. Immunol. Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations. 2019-03-28 10.1016/j.jaci.2019.01.052 5 view
Wolock Cell Syst Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data. 2019-03-28 10.1016/j.cels.2018.11.005 view
Biočanin Lab Chip Simplified Drop-seq workflow with minimized bead loss using a bead capture and processing microfluidic chip. 2019-03-28 10.1039/c9lc00014c 3 view
Wang Cell Stem Cell A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth. 2019-03-27 10.1016/j.stem.2019.01.011 view
Srivastava Genome Biol. Alevin efficiently estimates accurate gene abundances from dscRNA-seq data. 2019-03-27 10.1186/s13059-019-1670-y 9 view
Thyme Cell Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. 2019-03-26 10.1016/j.cell.2019.01.048 21 view
Farbehi Elife Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury. 2019-03-26 10.7554/eLife.43882 14 view
Riemondy JCI Insight Single cell RNA sequencing identifies TGFβ as a key regenerative cue following LPS-induced lung injury. 2019-03-26 10.1172/jci.insight.123637 view
McGinnis Cell Syst DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors. 2019-03-26 10.1016/j.cels.2019.03.003 71 view
Arck J. Reprod. Immunol. When 3 Rs meet a forth R: Replacement, reduction and refinement of animals in research on reproduction. 2019-03-25 10.1016/j.jri.2019.03.004 5 view
Li IEEE/ACM Trans Comput Biol Bioinform Single-Cell RNA Sequencing Data Interpretation by Evolutionary Multiobjective Clustering. 2019-03-25 10.1109/TCBB.2019.2906601 2 view
Denyer Dev. Cell Spatiotemporal Developmental Trajectories in the Arabidopsis Root Revealed Using High-Throughput Single-Cell RNA Sequencing. 2019-03-25 10.1016/j.devcel.2019.02.022 49 view
Weng Cell Stem Cell Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis. 2019-03-23 10.1016/j.stem.2019.03.006 view
Giordani Mol. Cell High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations. 2019-03-22 10.1016/j.molcel.2019.02.026 35 view
Lun Genome Biol. EmptyDrops: distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data. 2019-03-22 10.1186/s13059-019-1662-y 11 view
Ottersbach Biochem. Soc. Trans. Endothelial-to-haematopoietic transition: an update on the process of making blood. 2019-03-22 10.1042/BST20180320 2 view
Setty Nat. Biotechnol. Characterization of cell fate probabilities in single-cell data with Palantir. 2019-03-21 10.1038/s41587-019-0068-4 25 view
Biendarra-Tiegs Stem Cells Dev. Single-cell RNA-seq and optical electrophysiology of human induced pluripotent stem cell-derived cardiomyocytes reveal discordance between cardiac subtype-associated gene expression patterns and electrophysiological phenotypes. 2019-03-20 10.1089/scd.2019.0030 view
Grive PLoS Genet. Dynamic transcriptome profiles within spermatogonial and spermatocyte populations during postnatal testis maturation revealed by single-cell sequencing. 2019-03-20 10.1371/journal.pgen.1007810 16 view
Singh Sci Rep In situ 10-cell RNA sequencing in tissue and tumor biopsy samples. 2019-03-20 10.1038/s41598-019-41235-9 2 view
Mizuhashi J. Bone Miner. Res. Growth plate borderline chondrocytes behave as transient mesenchymal precursor cells. 2019-03-19 10.1002/jbmr.3719 8 view
Wolf Genome Biol. PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells. 2019-03-19 10.1186/s13059-019-1663-x 87 view
Antolović Development Transition state dynamics during a stochastic fate choice. 2019-03-19 10.1242/dev.173740 8 view
Ernst Nat Commun Staged developmental mapping and X chromosome transcriptional dynamics during mouse spermatogenesis. 2019-03-19 10.1038/s41467-019-09182-1 20 view
Ronning Sci Rep Molecular profiling of resident and infiltrating mononuclear phagocytes during rapid adult retinal degeneration using single-cell RNA sequencing. 2019-03-19 10.1038/s41598-019-41141-0 4 view
Yap Cell Rep In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors. 2019-03-19 10.1016/j.celrep.2019.02.083 5 view
Stévant Cell Rep Dissecting Cell Lineage Specification and Sex Fate Determination in Gonadal Somatic Cells Using Single-Cell Transcriptomics. 2019-03-19 10.1016/j.celrep.2019.02.069 view
Giandomenico Nat. Neurosci. Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output. 2019-03-18 10.1038/s41593-019-0350-2 29 view
Frishberg Nat. Methods Cell composition analysis of bulk genomics using single-cell data. 2019-03-18 10.1038/s41592-019-0355-5 24 view
Deng Nat. Methods Scalable analysis of cell-type composition from single-cell transcriptomics using deep recurrent learning. 2019-03-18 10.1038/s41592-019-0353-7 13 view
Okada Biochem. Biophys. Res. Commun. Transcriptionally distinct mesenchymal stem/stromal cells circulate in fetus. 2019-03-16 10.1016/j.bbrc.2019.03.033 view
Kubo Nucleic Acids Res. Single-cell transcriptome analysis of Physcomitrella leaf cells during reprogramming using microcapillary manipulation. 2019-03-15 10.1093/nar/gkz181 7 view
Shin Clin Lymphoma Myeloma Leuk Characteristics of Waldenström Macroglobulinemia in Korean Patients According to Mutational Status of MYD88 and CXCR4: Analysis Using Ultra-Deep Sequencing. 2019-03-15 10.1016/j.clml.2019.03.009 2 view
Guo Development Defining developmental diversification of diencephalon neurons through single-cell gene expression profiling. 2019-03-14 10.1242/dev.174284 view
Paolillo Clin. Chem. Single-Cell Genomics. 2019-03-14 10.1373/clinchem.2017.283895 6 view
Chen Sci Rep Single-cell transcriptome analysis identifies distinct cell types and niche signaling in a primary gastric organoid model. 2019-03-14 10.1038/s41598-019-40809-x 5 view
Mucenski Sci Rep Single cell RNA-seq study of wild type and Hox9,10,11 mutant developing uterus. 2019-03-14 10.1038/s41598-019-40923-w 6 view
Dai Nucleic Acids Res. Cell-specific network constructed by single-cell RNA sequencing data. 2019-03-13 10.1093/nar/gkz172 view
Durif Bioinformatics Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis. 2019-03-13 10.1093/bioinformatics/btz177 12 view
O'Sullivan J. Am. Soc. Nephrol. Complementary Roles for Single-Nucleus and Single-Cell RNA Sequencing in Kidney Disease Research. 2019-03-13 10.1681/ASN.2019020112 view
Zachs Nat Commun Noninvasive ultrasound stimulation of the spleen to treat inflammatory arthritis. 2019-03-12 10.1038/s41467-019-08721-0 view
Veerman Cell Rep Single-Cell Analysis Reveals Heterogeneity of High Endothelial Venules and Different Regulation of Genes Controlling Lymphocyte Entry to Lymph Nodes. 2019-03-12 10.1016/j.celrep.2019.02.042 9 view
Ranum Cell Rep Insights into the Biology of Hearing and Deafness Revealed by Single-Cell RNA Sequencing. 2019-03-12 10.1016/j.celrep.2019.02.053 view
Wainer Katsir BMC Genomics Human genes escaping X-inactivation revealed by single cell expression data. 2019-03-12 10.1186/s12864-019-5507-6 view
Francesconi Elife Single cell RNA-seq identifies the origins of heterogeneity in efficient cell transdifferentiation and reprogramming. 2019-03-12 10.7554/eLife.41627 9 view
McCann J. Clin. Invest. Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β-induced Serpine1. 2019-03-11 10.1172/JCI123106 11 view
Mickelsen Nat. Neurosci. Single-cell transcriptomic analysis of the lateral hypothalamic area reveals molecularly distinct populations of inhibitory and excitatory neurons. 2019-03-11 10.1038/s41593-019-0349-8 30 view
Klaus Nat. Med. Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia. 2019-03-11 10.1038/s41591-019-0371-0 14 view
Peyser Am. J. Respir. Cell Mol. Biol. Defining the Activated Fibroblast Population in Lung Fibrosis Using Single Cell Sequencing. 2019-03-08 10.1165/rcmb.2018-0313OC 12 view
Song Analyst Single cell transcriptomics: moving towards multi-omics. 2019-03-08 10.1039/c8an01852a view
Delile Development Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord. 2019-03-07 10.1242/dev.173807 32 view
Fu J. Am. Soc. Nephrol. Single-Cell RNA Profiling of Glomerular Cells Shows Dynamic Changes in Experimental Diabetic Kidney Disease. 2019-03-07 10.1681/ASN.2018090896 6 view
Treutlein Cell Stem Cell Evaluation of Wu et al.: Strengthening Single-Cell Bioinformatic Comparisons for Improving Organoid Differentiation. 2019-03-07 10.1016/j.stem.2019.02.010 view
Tian Curr. Opin. Nephrol. Hypertens. The myriad possibility of kidney organoids. 2019-03-06 10.1097/MNH.0000000000000498 view
Miyoshi Dev. Dyn. Kidney Organoids in Translational Medicine: Disease Modeling and Regenerative Medicine. 2019-03-06 10.1002/dvdy.22 6 view
Cheng Cell Rep Single-Cell RNA-Seq Reveals Cellular Heterogeneity of Pluripotency Transition and X Chromosome Dynamics during Early Mouse Development. 2019-03-05 10.1016/j.celrep.2019.02.031 5 view
Kwon iScience Functional Heterogeneity of Mouse Prostate Stromal Cells Revealed by Single-Cell RNA-Seq. 2019-03-02 10.1016/j.isci.2019.02.032 3 view
See Front Immunol Corrigendum: A Single-Cell Sequencing Guide for Immunologists. 2019-03-01 10.3389/fimmu.2019.00278 view
Pandit Front Immunol Stochastic Inheritance of Division and Death Times Determines the Size and Phenotype of CD8+ T Cell Families. 2019-03-01 10.3389/fimmu.2019.00436 view
Randolph Regen Eng Transl Med Human beta cells generated from pluripotent stem cells or cellular reprogramming for curing diabetes. 2019-03-01 10.1007/s40883-018-0082-y view
Untereiner FASEB J. GABA promotes β-cell proliferation, but does not overcome impaired glucose homeostasis associated with diet-induced obesity. 2019-03-01 10.1096/fj.201801397R 18 view
Yu FASEB J. Data driven mathematical modeling reveals the dynamic mechanism of MSC-induced neovascularization. 2019-03-01 10.1096/fj.201801652R 1 view
Goldman Front Genet The Impact of Heterogeneity on Single-Cell Sequencing. 2019-03-01 10.3389/fgene.2019.00008 3 view
Okawa Nucleic Acids Res. A general computational approach to predicting synergistic transcriptional cores that determine cell subpopulation identities. 2019-03-01 10.1093/nar/gkz147 view
Ding Nucleic Acids Res. Cell lineage inference from SNP and scRNA-Seq data. 2019-03-01 10.1093/nar/gkz146 4 view
Cho Genomics Inform Identification of ERBB Pathway-Activated Cells in Triple-Negative Breast Cancer. 2019-03-01 10.5808/GI.2019.17.1.e3 1 view
Marques Methods Mol. Biol. Single-Cell RNA Sequencing of Oligodendrocyte Lineage Cells from the Mouse Central Nervous System. 2019-03-01 10.1007/978-1-4939-9072-6_1 view
Zheng Bioinformatics SinNLRR: a robust subspace clustering method for cell type detection by nonnegative and low rank representation. 2019-03-01 10.1093/bioinformatics/btz139 view
Urrutia Bioinformatics Destin: toolkit for single-cell analysis of chromatin accessibility. 2019-03-01 10.1093/bioinformatics/btz141 5 view
Vickman Mol. Cancer Res. Cholesterol Sulfotransferase SULT2B1b Modulates Sensitivity to Death Receptor Ligand TNF alpha in Castration Resistant Prostate Cancer. 2019-03-01 10.1158/1541-7786.MCR-18-1054 view
Liao Development Revealing cellular and molecular transitions in neonatal germ cell differentiation using Single-cell RNA sequencing. 2019-03-01 10.1242/dev.174953 4 view
Long Cell Death Differ. Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation. 2019-03-01 10.1038/s41418-019-0310-0 4 view
Cardozo Front Genet webCEMiTool: Co-expression Modular Analysis Made Easy. 2019-03-01 10.3389/fgene.2019.00146 view
Torroja Front Genet Corrigendum: Digitaldlsorter: Deep-Learning on scRNA-Seq to Deconvolute Gene Expression Data. 2019-03-01 10.3389/fgene.2019.01373 view
Theorell PLoS ONE Determination of essential phenotypic elements of clusters in high-dimensional entities-DEPECHE. 2019-03-01 10.1371/journal.pone.0203247 3 view
Maj Front Mol Neurosci 20 Years of Secretagogin: Exocytosis and Beyond. 2019-03-01 10.3389/fnmol.2019.00029 2 view
Sarma Lab Chip A diffusion-based microfluidic device for single-cell RNA-seq. 2019-02-28 10.1039/c8lc00967h 3 view
Damiani PLoS Comput. Biol. Integration of single-cell RNA-seq data into population models to characterize cancer metabolism. 2019-02-28 10.1371/journal.pcbi.1006733 9 view
Zheng Proc. Natl. Acad. Sci. U.S.A. COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis. 2019-02-28 10.1073/pnas.1819303116 4 view
Arendt Curr. Opin. Neurobiol. Evolution of neuronal types and families. 2019-02-28 10.1016/j.conb.2019.01.022 9 view
Apóstolo Curr. Opin. Neurobiol. Compartmentalized distributions of neuronal and glial cell-surface proteins pattern the synaptic network. 2019-02-28 10.1016/j.conb.2019.01.025 4 view
Bakouny Eur Urol Focus State of the Future: Translational Approaches in Renal Cell Carcinoma in the Immunotherapy Era. 2019-02-28 10.1016/j.euf.2019.02.014 1 view
Ye RNA Biol Role of alternative polyadenylation dynamics in acute myeloid leukemia at single-cell resolution. 2019-02-27 10.1080/15476286.2019.1586139 view
Angelidis Nat Commun An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics. 2019-02-27 10.1038/s41467-019-08831-9 66 view
Liu Sci Data Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells. 2019-02-26 10.1038/sdata.2019.31 view
Yuan FASEB J. Conserved pathway activation following xenogeneic, heterotypic fusion. 2019-02-26 10.1096/fj.201801700R view
O'Koren Immunity Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration. 2019-02-26 10.1016/j.immuni.2019.02.007 view
Xie Nucleic Acids Res. SuperCT: a supervised-learning framework for enhanced characterization of single-cell transcriptomic profiles. 2019-02-25 10.1093/nar/gkz116 12 view
Bai Genomics Screen technical noise in single cell RNA sequencing data. 2019-02-22 10.1016/j.ygeno.2019.02.014 1 view
Kalamakis Cell Quiescence Modulates Stem Cell Maintenance and Regenerative Capacity in the Aging Brain. 2019-02-22 10.1016/j.cell.2019.01.040 15 view
van Galen Cell Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. 2019-02-22 10.1016/j.cell.2019.01.031 view
Kurotaki Blood Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice. 2019-02-22 10.1182/blood-2018-06-857789 8 view
Levitin Mol. Syst. Biol. De novo gene signature identification from single-cell RNA-seq with hierarchical Poisson factorization. 2019-02-22 10.15252/msb.20188557 18 view
Chen Cell. Mol. Immunol. Revolutionizing immunology with single-cell RNA sequencing. 2019-02-22 10.1038/s41423-019-0214-4 11 view
Ma JCI Insight Single-cell RNA sequencing of lung adenocarcinoma reveals heterogeneity of immune response-related genes. 2019-02-21 10.1172/jci.insight.121387 view
Lin JCI Insight Single-cell analysis of fate-mapped macrophages reveals heterogeneity, including stem-like properties, during atherosclerosis progression and regression. 2019-02-21 10.1172/jci.insight.124574 40 view
Huang Curr. Opin. Nephrol. Hypertens. The kidney transcriptome, from single cells to whole organs and back. 2019-02-21 10.1097/MNH.0000000000000495 view
Hochane PLoS Biol. Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development. 2019-02-21 10.1371/journal.pbio.3000152 view
Jadhav Cell Dissecting Cell Lineages: From Microscope to Kaleidoscope. 2019-02-21 10.1016/j.cell.2019.01.054 view
Moussa J. Comput. Biol. Locality Sensitive Imputation for Single Cell RNA-Seq Data. 2019-02-20 10.1089/cmb.2018.0236 view
Peng PLoS Comput. Biol. A component overlapping attribute clustering (COAC) algorithm for single-cell RNA sequencing data analysis and potential pathobiological implications. 2019-02-19 10.1371/journal.pcbi.1006772 3 view
Frank Proc. Natl. Acad. Sci. U.S.A. Early lineage specification defines alveolar epithelial ontogeny in the murine lung. 2019-02-19 10.1073/pnas.1813952116 15 view
Mentis Cell. Mol. Life Sci. Helicobacter pylori infection and gastric cancer biology: tempering a double-edged sword. 2019-02-19 10.1007/s00018-019-03044-1 4 view
Schultze Immunity Emerging Principles in Myelopoiesis at Homeostasis and during Infection and Inflammation. 2019-02-19 10.1016/j.immuni.2019.01.019 8 view
Arranz Lancet Neurol The role of astroglia in Alzheimer's disease: pathophysiology and clinical implications. 2019-02-19 10.1016/S1474-4422(18)30490-3 view
Li Dev. Cell Rate of Progression through a Continuum of Transit-Amplifying Progenitor Cell States Regulates Blood Cell Production. 2019-02-18 10.1016/j.devcel.2019.01.026 6 view
Wang Pediatr. Res. A novel in vitro model of primary human pediatric lung epithelial cells. 2019-02-18 10.1038/s41390-019-0340-9 13 view
Rashid Bioinformatics Dhaka: Variational Autoencoder for Unmasking Tumor Heterogeneity from Single Cell Genomic Data. 2019-02-15 10.1093/bioinformatics/btz095 4 view
Xiang Cell Stem Cell hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids. 2019-02-14 10.1016/j.stem.2018.12.015 view
Nowinski Environ. Microbiol. Microdiversity and Temporal Dynamics of Marine Bacterial Dimethylsulfoniopropionate Genes. 2019-02-14 10.1111/1462-2920.14560 3 view
Zhao Hepatology Tissue repair in the mouse liver following acute carbon tetrachloride depends on injury-induced Wnt/β-catenin signaling. 2019-02-14 10.1002/hep.30563 view
Monier PLoS Comput. Biol. IRIS-EDA: An integrated RNA-Seq interpretation system for gene expression data analysis. 2019-02-14 10.1371/journal.pcbi.1006792 8 view
Haage Acta Neuropathol Commun Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma. 2019-02-14 10.1186/s40478-019-0665-y 28 view
Dangi Cell. Mol. Immunol. Emerging approaches and technologies in transplantation: the potential game changers. 2019-02-13 10.1038/s41423-019-0207-3 2 view
Wu Mol. Cells Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging. 2019-02-13 10.14348/molcells.2019.0006 5 view
Guo Mol. Cell Resolving Cell Fate Decisions during Somatic Cell Reprogramming by Single-Cell RNA-Seq. 2019-02-13 10.1016/j.molcel.2019.01.042 7 view
Cui Cell Rep Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart. 2019-02-12 10.1016/j.celrep.2019.01.079 73 view
Tyler Cell Rep PyMINEr Finds Gene and Autocrine-Paracrine Networks from Human Islet scRNA-Seq. 2019-02-12 10.1016/j.celrep.2019.01.063 3 view
Choi Mol. Cells Dissecting Cellular Heterogeneity Using Single-Cell RNA Sequencing. 2019-02-12 10.14348/molcells.2019.2446 5 view
Linderman Nat. Methods Fast interpolation-based t-SNE for improved visualization of single-cell RNA-seq data. 2019-02-11 10.1038/s41592-018-0308-4 58 view
Sato Genome Biol. CellFishing.jl: an ultrafast and scalable cell search method for single-cell RNA sequencing. 2019-02-11 10.1186/s13059-019-1639-x view
Kim Immunol. Cell Biol. Macrophages in wound healing: activation and plasticity. 2019-02-11 10.1111/imcb.12236 14 view
Rodriguez-Meira Mol. Cell Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing. 2019-02-11 10.1016/j.molcel.2019.01.009 25 view
Guo Stem Cell Reports Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development. 2019-02-11 10.1016/j.stemcr.2019.01.022 10 view
Yu EMBO J. Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution. 2019-02-08 10.15252/embj.2018100164 7 view
Guerrero-Juarez Nat Commun Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds. 2019-02-08 10.1038/s41467-018-08247-x 19 view
Gutierrez-Arcelus Nat Commun Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions. 2019-02-08 10.1038/s41467-019-08604-4 22 view
Koelwyn Trends Immunol. Defining Macrophages in the Heart One Cell at a Time. 2019-02-08 10.1016/ view
Wizeman Elife Specification of diverse cell types during early neurogenesis of the mouse cerebellum. 2019-02-08 10.7554/eLife.42388 4 view
Carr Cell Stem Cell Mesenchymal Precursor Cells in Adult Nerves Contribute to Mammalian Tissue Repair and Regeneration. 2019-02-07 10.1016/j.stem.2018.10.024 11 view
Tan Cell Stem Cell Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass. 2019-02-07 10.1016/j.stem.2019.01.010 5 view
Mayer Neuron Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex. 2019-02-07 10.1016/j.neuron.2019.01.027 10 view
Watcham Blood New Insights into Haematopoietic Differentiation Landscapes from scRNA-seq. 2019-02-06 10.1182/blood-2018-08-835355 view
Szczerba Nature Neutrophils escort circulating tumour cells to enable cell cycle progression. 2019-02-06 10.1038/s41586-019-0915-y 130 view
Schreurs Immunity Human Fetal TNF-α-Cytokine-Producing CD4+ Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life. 2019-02-05 10.1016/j.immuni.2018.12.010 view
Ekiz JCI Insight MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers. 2019-02-05 10.1172/jci.insight.126543 6 view
Mould JCI Insight Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets. 2019-02-05 10.1172/jci.insight.126556 31 view
Sohni Cell Rep The Neonatal and Adult Human Testis Defined at the Single-Cell Level. 2019-02-05 10.1016/j.celrep.2019.01.045 36 view
Poczobutt Am. J. Respir. Crit. Care Med. Defining the Cell Types That Drive IPF Using Single Cell RNA Sequencing. 2019-02-04 10.1164/rccm.201901-0197ED view
Ryu Plant Physiol. Single-cell RNA sequencing resolves molecular relationships among individual plant cells. 2019-02-04 10.1104/pp.18.01482 71 view
Borcherding Clin. Cancer Res. Single-cell profiling of cutaneous T-cell lymphoma reveals underlying heterogeneity associated with disease progression. 2019-02-04 10.1158/1078-0432.CCR-18-3309 10 view
Risso Nat Commun Publisher Correction: A general and flexible method for signal extraction from single-cell RNA-seq data. 2019-02-04 10.1038/s41467-019-08614-2 1 view
Tiklová Nat Commun Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development. 2019-02-04 10.1038/s41467-019-08453-1 47 view
Saint Nat Microbiol Single-cell imaging and RNA sequencing reveal patterns of gene expression heterogeneity during fission yeast growth and adaptation. 2019-02-04 10.1038/s41564-018-0330-4 10 view
Nadal-Ribelles Nat Microbiol Sensitive high-throughput single-cell RNA-seq reveals within-clonal transcript correlations in yeast populations. 2019-02-04 10.1038/s41564-018-0346-9 1 view
Potter Methods Mol. Biol. Dissociation of Tissues for Single-Cell Analysis. 2019-02-01 10.1007/978-1-4939-9021-4_5 3 view
Brazovskaja Curr. Opin. Biotechnol. High-throughput single-cell transcriptomics on organoids. 2019-02-01 10.1016/j.copbio.2018.11.002 5 view
Jiang Methods Mol. Biol. Quality Control of Single-Cell RNA-seq. 2019-02-01 10.1007/978-1-4939-9057-3_1 20 view
Bacher Methods Mol. Biol. Normalization for Single-Cell RNA-Seq Data Analysis. 2019-02-01 10.1007/978-1-4939-9057-3_2 view
Kim Methods Mol. Biol. Analysis of Technical and Biological Variability in Single-Cell RNA Sequencing. 2019-02-01 10.1007/978-1-4939-9057-3_3 view
Shekhar Methods Mol. Biol. Identification of Cell Types from Single-Cell Transcriptomic Data. 2019-02-01 10.1007/978-1-4939-9057-3_4 2 view
Sun Methods Mol. Biol. scMCA: A Tool to Define Mouse Cell Types Based on Single-Cell Digital Expression. 2019-02-01 10.1007/978-1-4939-9057-3_6 1 view
Fan Methods Mol. Biol. Differential Pathway Analysis. 2019-02-01 10.1007/978-1-4939-9057-3_7 view
Ji Methods Mol. Biol. Pseudotime Reconstruction Using TSCAN. 2019-02-01 10.1007/978-1-4939-9057-3_8 view
Chen Methods Mol. Biol. Estimating Differentiation Potency of Single Cells Using Single-Cell Entropy (SCENT). 2019-02-01 10.1007/978-1-4939-9057-3_9 3 view
Lamere Methods Mol. Biol. Inference of Gene Co-expression Networks from Single-Cell RNA-Sequencing Data. 2019-02-01 10.1007/978-1-4939-9057-3_10 view
Dong Methods Mol. Biol. Single-Cell Allele-Specific Gene Expression Analysis. 2019-02-01 10.1007/978-1-4939-9057-3_11 5 view
Huang Methods Mol. Biol. Using BRIE to Detect and Analyze Splicing Isoforms in scRNA-Seq Data. 2019-02-01 10.1007/978-1-4939-9057-3_12 view
Lindeman Methods Mol. Biol. Antigen Receptor Sequence Reconstruction and Clonality Inference from scRNA-Seq Data. 2019-02-01 10.1007/978-1-4939-9057-3_15 2 view
Mongia Front Genet McImpute: Matrix Completion Based Imputation for Single Cell RNA-seq Data. 2019-02-01 10.3389/fgene.2019.00009 7 view
Winterhoff Curr. Opin. Obstet. Gynecol. Single-cell sequencing in ovarian cancer: a new frontier in precision medicine. 2019-02-01 10.1097/GCO.0000000000000516 3 view
Yang Front Genet Editorial: Bioinformatics Analysis of Single Cell Sequencing Data and Applications in Precision Medicine. 2019-02-01 10.3389/fgene.2019.01358 view
Gallivan Front Genet Analysis of Single-Cell Gene Pair Coexpression Landscapes by Stochastic Kinetic Modeling Reveals Gene-Pair Interactions in Development. 2019-02-01 10.3389/fgene.2019.01387 view
Blecher-Gonen Cell Syst Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity. 2019-02-01 10.1016/j.cels.2019.01.001 7 view
Papadopoulos Bioinformatics PROSSTT: probabilistic simulation of single-cell RNA-seq data for complex differentiation processes. 2019-02-01 10.1093/bioinformatics/btz078 6 view
Yu Methods Mol. Biol. Usage of Single-Cell RNA Sequencing to Unveil Immune Lymphoid Cell Precursors. 2019-02-01 10.1007/978-1-4939-8885-3_5 view
Wardemann Methods Mol. Biol. Expression Cloning of Antibodies from Single Human B Cells. 2019-02-01 10.1007/978-1-4939-9151-8_5 view
Bagnoli Methods Mol. Biol. Studying Cancer Heterogeneity by Single-Cell RNA Sequencing. 2019-02-01 10.1007/978-1-4939-9151-8_14 view
Mou Front Genet Reproducibility of Methods to Detect Differentially Expressed Genes from Single-Cell RNA Sequencing. 2019-02-01 10.3389/fgene.2019.01331 view
Zhou Stem Cells Int Stem Cells and Cellular Origins of Mammary Gland: Updates in Rationale, Controversies, and Cancer Relevance. 2019-02-01 10.1155/2019/4247168 4 view
Penaranda ACS Infect Dis Single-Cell RNA Sequencing to Understand Host-Pathogen Interactions. 2019-01-31 10.1021/acsinfecdis.8b00369 4 view
Stuart Nat. Rev. Genet. Integrative single-cell analysis. 2019-01-29 10.1038/s41576-019-0093-7 129 view
Zhu Genes (Basel) A Hybrid Clustering Algorithm for Identifying Cell Types from Single-Cell RNA-Seq Data. 2019-01-29 10.3390/genes10020098 4 view
Rosenzweig Nat Commun PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. 2019-01-28 10.1038/s41467-019-08352-5 13 view
Schiebinger Cell Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming. 2019-01-28 10.1016/j.cell.2019.01.006 39 view
Peng Cell Molecular Classification and Comparative Taxonomics of Foveal and Peripheral Cells in Primate Retina. 2019-01-28 10.1016/j.cell.2019.01.004 71 view
Lush Elife scRNA-Seq reveals distinct stem cell populations that drive hair cell regeneration after loss of Fgf and Notch signaling. 2019-01-25 10.7554/eLife.44431 view
Collin Stem Cells CRX expression in pluripotent stem cell derived photoreceptors marks a transplantable subpopulation of early cones. 2019-01-25 10.1002/stem.2974 1 view
Daughtry Genome Res. Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion. 2019-01-25 10.1101/gr.239830.118 10 view
Lawlor Elife Nephron progenitor commitment is a stochastic process influenced by cell migration. 2019-01-24 10.7554/eLife.41156 14 view
Williams Curr. Opin. Neurobiol. Neuronal cell types in the annelid Platynereis dumerilii. 2019-01-24 10.1016/j.conb.2018.12.008 2 view
Maehara Int J Oral Maxillofac Surg Clinical features and mechanistic insights regarding IgG4-related dacryoadenitis and sialoadenitis: a review. 2019-01-24 10.1016/j.ijom.2019.01.006 view
Sahara Dev. Cell Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract. 2019-01-24 10.1016/j.devcel.2019.01.005 5 view
Ba Funct. Integr. Genomics Single-cell transcriptome provides novel insights into antler stem cells, a cell type capable of mammalian organ regeneration. 2019-01-23 10.1007/s10142-019-00659-2 view
Hamza Proc. Natl. Acad. Sci. U.S.A. Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. 2019-01-23 10.1073/pnas.1814102116 10 view
Eraslan Nat Commun Single-cell RNA-seq denoising using a deep count autoencoder. 2019-01-23 10.1038/s41467-018-07931-2 50 view
Miragaia Immunity Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation. 2019-01-23 10.1016/j.immuni.2019.01.001 62 view
Messmer Cell Rep Transcriptional Heterogeneity in Naive and Primed Human Pluripotent Stem Cells at Single-Cell Resolution. 2019-01-22 10.1016/j.celrep.2018.12.099 view
Darde Bioinformatics The ReproGenomics Viewer: a multi-omics and cross-species resource compatible with single-cell studies for the reproductive science community. 2019-01-22 10.1093/bioinformatics/btz047 9 view
Huss Hum. Hered. Comparison of SureSelect and Nextera Exome Capture Performance in Single-Cell Sequencing. 2019-01-22 10.1159/000490506 1 view
Yang BMC Syst Biol Correction to: MISC: missing imputation for single-cell RNA sequencing data. 2019-01-22 10.1186/s12918-019-0681-3 view
Wang Nat Commun Bulk tissue cell type deconvolution with multi-subject single-cell expression reference. 2019-01-22 10.1038/s41467-018-08023-x 51 view
Chapuy Mucosal Immunol Two distinct colonic CD14+ subsets characterized by single-cell RNA profiling in Crohn's disease. 2019-01-22 10.1038/s41385-018-0126-0 view
Kiselev Nat. Rev. Genet. Publisher Correction: Challenges in unsupervised clustering of single-cell RNA-seq data. 2019-01-22 10.1038/s41576-019-0095-5 5 view
Li Nat. Immunol. Memory CD4+ T cells are generated in the human fetal intestine. 2019-01-21 10.1038/s41590-018-0294-9 view
Ntranos Nat. Methods A discriminative learning approach to differential expression analysis for single-cell RNA-seq. 2019-01-21 10.1038/s41592-018-0303-9 22 view
Wang BMC Bioinformatics Comparative analysis of differential gene expression analysis tools for single-cell RNA sequencing data. 2019-01-18 10.1186/s12859-019-2599-6 view
Castro Dias Sci Rep Claudin-3-deficient C57BL/6J mice display intact brain barriers. 2019-01-18 10.1038/s41598-018-36731-3 view
Tambe BMC Bioinformatics Barcode identification for single cell genomics. 2019-01-17 10.1186/s12859-019-2612-0 1 view
Bassler Annu. Rev. Immunol. The Myeloid Cell Compartment-Cell by Cell. 2019-01-16 10.1146/annurev-immunol-042718-041728 22 view
Chowdhury IEEE/ACM Trans Comput Biol Bioinform (Differential) Co-Expression Analysis of Gene Expression: A Survey of Best Practices. 2019-01-16 10.1109/TCBB.2019.2893170 3 view
Adorjan J. Anat. Neuroserpin expression during human brain development and in adult brain revealed by immunohistochemistry and single cell RNA sequencing. 2019-01-15 10.1111/joa.12931 3 view
Kiser FASEB J. Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones. 2019-01-15 10.1096/fj.201802493R 5 view
Xu Elife Hedgehog signaling patterns the oral-aboral axis of the mandibular arch. 2019-01-14 10.7554/eLife.40315 8 view
Hernandez-Barco Clin. Cancer Res. No Cell Left Unturned: Intraductal Papillary Mucinous Neoplasm Heterogeneity. 2019-01-14 10.1158/1078-0432.CCR-18-3877 2 view
Aran Nat. Immunol. Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage. 2019-01-14 10.1038/s41590-018-0276-y 128 view
Gao Bioinformatics ClusterMap: Compare multiple Single Cell RNA-Seq datasets across different experimental conditions. 2019-01-14 10.1093/bioinformatics/btz024 3 view
Rentzsch Curr. Opin. Neurobiol. Modern genomic tools reveal the structural and cellular diversity of cnidarian nervous systems. 2019-01-14 10.1016/j.conb.2018.12.004 1 view
Asante Environ Microbiol Rep Understanding antimicrobial discovery and resistance from a metagenomic and metatranscriptomic perspective: Advances and applications. 2019-01-13 10.1111/1758-2229.12735 15 view
Liu J Transl Med Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture. 2019-01-11 10.1186/s12967-018-1766-2 4 view
Loo Nat Commun Single-cell transcriptomic analysis of mouse neocortical development. 2019-01-11 10.1038/s41467-018-08079-9 30 view
Stratton J Vis Exp Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues. 2019-01-10 10.3791/58709 view
Davis Mol. Phylogenet. Evol. Genome-scale phylogenetics reveals a monophyletic Zoopagales (Zoopagomycota, Fungi). 2019-01-10 10.1016/j.ympev.2019.01.006 3 view
Schmidt ILAR J Rational Design and In Vivo Characterization of Vaccine Adjuvants. 2019-01-09 10.1093/ilar/ily018 1 view
O'Neal J. Virol. West Nile virus-inclusive single-cell RNA sequencing reveals heterogeneity in the type I interferon response within single cells. 2019-01-09 10.1128/JVI.01778-18 view
Takahashi Proc. Natl. Acad. Sci. U.S.A. Autocrine regulation of mesenchymal progenitor cell fates orchestrates tooth eruption. 2019-01-08 10.1073/pnas.1810200115 14 view
Mizrak Cell Rep Single-Cell Analysis of Regional Differences in Adult V-SVZ Neural Stem Cell Lineages. 2019-01-08 10.1016/j.celrep.2018.12.044 18 view
Manipur Int. J. Biochem. Cell Biol. Exploiting single-cell RNA sequencing data to link alternative splicing and cancer heterogeneity: a computational approach. 2019-01-08 10.1016/j.biocel.2018.12.015 view
Ciucci Immunity The Emergence and Functional Fitness of Memory CD4+ T Cells Require the Transcription Factor Thpok. 2019-01-08 10.1016/j.immuni.2018.12.019 view
Anaparthy Cold Spring Harb Perspect Med Single-Cell Applications of Next-Generation Sequencing. 2019-01-07 10.1101/cshperspect.a026898 2 view
Kiselev Nat. Rev. Genet. Challenges in unsupervised clustering of single-cell RNA-seq data. 2019-01-07 10.1038/s41576-018-0088-9 view
Liu Dev. Cell Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. 2019-01-07 10.1016/j.devcel.2018.11.048 5 view
Crow Curr. Opin. Neurobiol. Single cell RNA-sequencing: replicability of cell types. 2019-01-06 10.1016/j.conb.2018.12.002 view
Wilson Pediatr. Nephrol. Kidney and organoid single-cell transcriptomics: the end of the beginning. 2019-01-04 10.1007/s00467-018-4177-y 4 view
Jang Blood Cancer J Molecular signatures of multiple myeloma progression through single cell RNA-Seq. 2019-01-03 10.1038/s41408-018-0160-x 11 view
Lang Cell Stem Cell Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. 2019-01-03 10.1016/j.stem.2018.10.023 21 view
Satoh J. Mol. Cell. Cardiol. High-throughput single-molecule RNA imaging analysis reveals heterogeneous responses of cardiomyocytes to hemodynamic overload. 2019-01-03 10.1016/j.yjmcc.2018.12.018 1 view
Larsson Nature Genomic encoding of transcriptional burst kinetics. 2019-01-02 10.1038/s41586-018-0836-1 view
Prodromidou Front Cell Neurosci Species-Specific miRNAs in Human Brain Development and Disease. 2019-01-01 10.3389/fncel.2019.00559 view
Krzak Front Genet Benchmark and Parameter Sensitivity Analysis of Single-Cell RNA Sequencing Clustering Methods. 2019-01-01 10.3389/fgene.2019.01253 view
Zhang Front Genet Revealing Dynamic Mechanisms of Cell Fate Decisions From Single-Cell Transcriptomic Data. 2019-01-01 10.3389/fgene.2019.01280 2 view
Chaudhry Front Cardiovasc Med Single-Cell RNA Sequencing of the Cardiovascular System: New Looks for Old Diseases. 2019-01-01 10.3389/fcvm.2019.00173 view
McCurdy PLoS ONE Deterministic column subset selection for single-cell RNA-Seq. 2019-01-01 10.1371/journal.pone.0210571 view
Torres Neurosurg. Clin. N. Am. Alterations in the Brain Microenvironment in Diffusely Infiltrating Low-Grade Glioma. 2019-01-01 10.1016/ 2 view
Franzén Database (Oxford) PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data. 2019-01-01 10.1093/database/baz046 view
Jansen Epilepsy Curr The Space-Time Continuum of Cortical Dysplasia. 2019-01-01 10.1177/1535759718822039 view
Kim Methods Mol. Biol. Single-Cell Library Preparation of iPSC-Derived Neural Stem Cells. 2019-01-01 10.1007/978-1-4939-9007-8_10 view
Kim Methods Mol. Biol. Bioinformatics Analysis of Single-Cell RNA-Seq Raw Data from iPSC-Derived Neural Stem Cells. 2019-01-01 10.1007/978-1-4939-9007-8_11 view
Dick Nat. Immunol. Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction. 2019-01-01 10.1038/s41590-018-0272-2 134 view
Whitsett Physiol. Rev. Building and Regenerating the Lung Cell by Cell. 2019-01-01 10.1152/physrev.00001.2018 22 view
Ma BMC Bioinformatics Single-cell gene expression analysis reveals β-cell dysfunction and deficit mechanisms in type 2 diabetes. 2018-12-31 10.1186/s12859-018-2519-1 5 view
Gan BMC Med Genomics Identification of cancer subtypes from single-cell RNA-seq data using a consensus clustering method. 2018-12-31 10.1186/s12920-018-0433-z view
Saito Neuron Differential NOVA2-Mediated Splicing in Excitatory and Inhibitory Neurons Regulates Cortical Development and Cerebellar Function. 2018-12-28 10.1016/j.neuron.2018.12.019 15 view
Field Stem Cell Reports Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes. 2018-12-28 10.1016/j.stemcr.2018.12.006 view
Li Bioinformatics Single-cell RNA-seq Interpretations using Evolutionary Multiobjective Ensemble Pruning. 2018-12-28 10.1093/bioinformatics/bty1056 9 view
Andor Blood Single-cell RNA-Seq of lymphoma cancers reveals malignant B cell types and co-expression of T cell immune checkpoints. 2018-12-27 10.1182/blood-2018-08-862292 1 view
Li Neuron Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing. 2018-12-27 10.1016/j.neuron.2018.12.006 106 view
Romagnoli BMC Genomics ddSeeker: a tool for processing Bio-Rad ddSEQ single cell RNA-seq data. 2018-12-24 10.1186/s12864-018-5249-x 1 view
Higdon J. Immunol. Methods Optimization of single-cell plate sorting for high throughput sequencing applications. 2018-12-24 10.1016/j.jim.2018.12.006 1 view
Yuan Genome Biol. SCOPE-Seq: a scalable technology for linking live cell imaging and single-cell RNA sequencing. 2018-12-24 10.1186/s13059-018-1607-x 8 view
Gasperini Cell A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. 2018-12-22 10.1016/j.cell.2018.11.029 71 view
Wang BMC Syst Biol The International Conference on Intelligent Biology and Medicine (ICIBM) 2018: systems biology on diverse data types. 2018-12-21 10.1186/s12918-018-0648-9 view
Chiu BMC Syst Biol scdNet: a computational tool for single-cell differential network analysis. 2018-12-21 10.1186/s12918-018-0652-0 4 view
Büttner Nat. Methods A test metric for assessing single-cell RNA-seq batch correction. 2018-12-20 10.1038/s41592-018-0254-1 28 view
Neirijnck Endocrinology The tumor suppressor PTEN regulates negatively Sertoli cell proliferation, testis size and sperm production in vivo. 2018-12-20 10.1210/en.2018-00892 view
Li Cell Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma. 2018-12-20 10.1016/j.cell.2018.11.043 105 view
Mok Dev. Cell Dermal Condensate Niche Fate Specification Occurs Prior to Formation and Is Placode Progenitor Dependent. 2018-12-20 10.1016/j.devcel.2018.11.034 11 view
van der Wijst Genome Med An integrative approach for building personalized gene regulatory networks for precision medicine. 2018-12-19 10.1186/s13073-018-0608-4 view
Stoeckius Genome Biol. Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics. 2018-12-19 10.1186/s13059-018-1603-1 33 view
Karmaus Nature Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. 2018-12-19 10.1038/s41586-018-0806-7 view
Gupta Dev. Cell Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. 2018-12-19 10.1016/j.devcel.2018.11.032 9 view
Egli Immunogenetics The genomic organization and expression pattern of the low-affinity Fc gamma receptors (FcγR) in the Göttingen minipig. 2018-12-18 10.1007/s00251-018-01099-1 1 view
Garieri Proc. Natl. Acad. Sci. U.S.A. Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts. 2018-12-18 10.1073/pnas.1806811115 18 view
Henry Cell Rep A Cellular Anatomy of the Normal Adult Human Prostate and Prostatic Urethra. 2018-12-18 10.1016/j.celrep.2018.11.086 31 view
Wang Genomics Proteomics Bioinformatics VASC: Dimension Reduction and Visualization of Single-cell RNA-seq Data by Deep Variational Autoencoder. 2018-12-18 10.1016/j.gpb.2018.08.003 16 view
Saikia Nat. Methods Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells. 2018-12-17 10.1038/s41592-018-0259-9 31 view
Shema Nat. Genet. Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution. 2018-12-17 10.1038/s41588-018-0290-x 31 view
Reyfman Am. J. Respir. Crit. Care Med. Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis. 2018-12-15 10.1164/rccm.201712-2410OC 138 view
Westerlund Biochem. Biophys. Res. Commun. EPAS1/HIF2α correlates with features of low-risk neuroblastoma and with adrenal chromaffin cell differentiation during sympathoadrenal development. 2018-12-15 10.1016/j.bbrc.2018.12.076 2 view
Croote Science High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes. 2018-12-14 10.1126/science.aau2599 36 view
Yang BMC Syst Biol MISC: missing imputation for single-cell RNA sequencing data. 2018-12-14 10.1186/s12918-018-0638-y 2 view
Yu Cytometry A An integrated enrichment system to facilitate isolation and molecular characterization of single cancer cells from whole blood. 2018-12-14 10.1002/cyto.a.23599 4 view
Schlenner Ann. Rheum. Dis. NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology. 2018-12-14 10.1136/annrheumdis-2018-213764 view
Freedman Nephron Better Being Single? Omics Improves Kidney Organoids. 2018-12-14 10.1159/000496009 4 view
Wang Cell Metab. Single-Cell RNA-Seq of the Pancreatic Islets--a Promise Not yet Fulfilled? 2018-12-14 10.1016/j.cmet.2018.11.016 16 view
Wu Haematologica Long noncoding RNAs of single hematopoietic stem and progenitor cells in healthy and dysplastic human bone marrow. 2018-12-13 10.3324/haematol.2018.208926 3 view
Collin Stem Cells Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina. 2018-12-12 10.1002/stem.2963 15 view
Thier Cell Stem Cell Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells. 2018-12-12 10.1016/j.stem.2018.11.015 view
Sa Int. J. Cancer Hypermutagenesis in untreated adult gliomas due to inherited mismatch mutations. 2018-12-11 10.1002/ijc.32054 4 view
Mann Cell Rep Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. 2018-12-11 10.1016/j.celrep.2018.11.056 26 view
Hao Bioinformatics Optimal Gene Filtering for Single-Cell data (OGFSC) - a gene filtering algorithm for single-cell RNA-seq data. 2018-12-10 10.1093/bioinformatics/bty1016 view
da Costa Urol. Oncol. Molecular tumor heterogeneity in muscle invasive bladder cancer: Biomarkers, subtypes, and implications for therapy. 2018-12-08 10.1016/j.urolonc.2018.11.015 view
Hochrein ACS Synth Biol Signal Transduction in Human Cell Lysate via Dynamic RNA Nanotechnology. 2018-12-07 10.1021/acssynbio.8b00424 4 view
Zanini Proc. Natl. Acad. Sci. U.S.A. Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengue. 2018-12-07 10.1073/pnas.1813819115 45 view
Chen Bioinformatics DensityPath: an algorithm to visualize and reconstruct cell state-transition path on density landscape for single-cell RNA sequencing data. 2018-12-07 10.1093/bioinformatics/bty1009 view
Kim Bioinformatics In silico error correction improves cfDNA mutation calling. 2018-12-06 10.1093/bioinformatics/bty1004 view
Oetjen JCI Insight Human bone marrow assessment by single-cell RNA sequencing, mass cytometry, and flow cytometry. 2018-12-06 10.1172/jci.insight.124928 view
Fujii Cell Stem Cell Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition. 2018-12-06 10.1016/j.stem.2018.11.016 26 view
Li BMC Cancer EGF/EGFR upregulates and cooperates with Netrin-4 to protect glioblastoma cells from DNA damage-induced senescence. 2018-12-04 10.1186/s12885-018-5056-4 2 view
Leigh Nat Commun Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution. 2018-12-04 10.1038/s41467-018-07604-0 25 view
Singer Nat Commun Single-cell mutation identification via phylogenetic inference. 2018-12-04 10.1038/s41467-018-07627-7 12 view
Bartoschek Nat Commun Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing. 2018-12-04 10.1038/s41467-018-07582-3 76 view
Tepe Cell Rep Single-Cell RNA-Seq of Mouse Olfactory Bulb Reveals Cellular Heterogeneity and Activity-Dependent Molecular Census of Adult-Born Neurons. 2018-12-04 10.1016/j.celrep.2018.11.034 15 view
Ren Genome Biol. Understanding tumor ecosystems by single-cell sequencing: promises and limitations. 2018-12-03 10.1186/s13059-018-1593-z 25 view
Chen Nat. Med. Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level. 2018-12-03 10.1038/s41591-018-0267-4 16 view
Wu J. Am. Soc. Nephrol. Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis. 2018-12-03 10.1681/ASN.2018090912 32 view
Becht Nat. Biotechnol. Dimensionality reduction for visualizing single-cell data using UMAP. 2018-12-03 10.1038/nbt.4314 362 view
Bonventre Kidney Int. Kidney organoids-a new tool for kidney therapeutic development. 2018-12-01 10.1016/j.kint.2018.07.029 1 view
McCracken Curr. Opin. Lipidol. Unravelling atherosclerotic heterogeneity by single cell RNA sequencing. 2018-12-01 10.1097/MOL.0000000000000559 view
Shih PLoS ONE Correction: Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq. 2018-12-01 10.1371/journal.pone.0208778 view
Yao PLoS ONE Exploiting antigen receptor information to quantify index switching in single-cell transcriptome sequencing experiments. 2018-12-01 10.1371/journal.pone.0208484 view
Huang Front Oncol Technical Advances in Single-Cell RNA Sequencing and Applications in Normal and Malignant Hematopoiesis. 2018-12-01 10.3389/fonc.2018.00582 2 view
Bakken PLoS ONE Single-nucleus and single-cell transcriptomes compared in matched cortical cell types. 2018-12-01 10.1371/journal.pone.0209648 21 view
Nikopoulou Biol. Chem. Ageing and sources of transcriptional heterogeneity. 2018-12-01 10.1515/hsz-2018-0449 1 view
Kim Dement Neurocogn Disord Genetics of Alzheimer's Disease. 2018-12-01 10.12779/dnd.2018.17.4.131 view
Sierant Genomics Inform Single-Cell Ssequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics Tools. 2018-12-01 10.5808/GI.2018.16.4.e17 view
Lopez Nat. Methods Deep generative modeling for single-cell transcriptomics. 2018-12-01 10.1038/s41592-018-0229-2 61 view
Ledergor Nat. Med. Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma. 2018-12-01 10.1038/s41591-018-0269-2 30 view
Massaia Front Cardiovasc Med Single Cell Gene Expression to Understand the Dynamic Architecture of the Heart. 2018-12-01 10.3389/fcvm.2018.00167 view
Peng Cell Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. 2018-11-29 10.1016/j.cell.2018.11.012 20 view
Riemondy Nucleic Acids Res. Recovery and analysis of transcriptome subsets from pooled single-cell RNA-seq libraries. 2018-11-29 10.1093/nar/gky1204 4 view
Barrett Stem Cells Dev. Human Wharton's Jelly Mesenchymal Stem Cells Show Unique Gene Expression Compared to Bone Marrow Mesenchymal Stem Cells Using Single-Cell RNA-Sequencing. 2018-11-28 10.1089/scd.2018.0132 view
Xin Nat Commun Single-cell RNA sequencing unveils an IL-10-producing helper subset that sustains humoral immunity during persistent infection. 2018-11-28 10.1038/s41467-018-07492-4 view
Wu Cell Syst Visualizing and Interpreting Single-Cell Gene Expression Datasets with Similarity Weighted Nonnegative Embedding. 2018-11-28 10.1016/j.cels.2018.10.015 22 view
Garris Immunity Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12. 2018-11-27 10.1016/j.immuni.2018.09.024 93 view
Hadi Nat Commun Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells. 2018-11-27 10.1038/s41467-018-07495-1 11 view
Ariss Nat Commun Single cell RNA-sequencing identifies a metabolic aspect of apoptosis in Rbf mutant. 2018-11-27 10.1038/s41467-018-07540-z 6 view
Kimmerling Genome Biol. Linking single-cell measurements of mass, growth rate, and gene expression. 2018-11-27 10.1186/s13059-018-1576-0 6 view
Zywitza Cell Rep Single-Cell Transcriptomics Characterizes Cell Types in the Subventricular Zone and Uncovers Molecular Defects Impairing Adult Neurogenesis. 2018-11-27 10.1016/j.celrep.2018.11.003 18 view
Bancells Nat Microbiol Revisiting the initial steps of sexual development in the malaria parasite Plasmodium falciparum. 2018-11-26 10.1038/s41564-018-0291-7 21 view
Zheng Mol. Immunol. A complex auxiliary: IL-17/Th17 signaling during type 1 diabetes progression. 2018-11-22 10.1016/j.molimm.2018.11.007 view
Sharma Nat Commun Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy. 2018-11-22 10.1038/s41467-018-07261-3 26 view
Alpár Curr. Opin. Neurobiol. Hypothalamic cell diversity: non-neuronal codes for long-distance volume transmission by neuropeptides. 2018-11-21 10.1016/j.conb.2018.10.012 4 view
Hammond Immunity Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes. 2018-11-21 10.1016/j.immuni.2018.11.004 115 view
Churko Nat Commun Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis. 2018-11-21 10.1038/s41467-018-07333-4 23 view
Singh Sci Rep Machine learning based classification of cells into chronological stages using single-cell transcriptomics. 2018-11-21 10.1038/s41598-018-35218-5 4 view
Poirion Nat Commun Using single nucleotide variations in single-cell RNA-seq to identify subpopulations and genotype-phenotype linkage. 2018-11-20 10.1038/s41467-018-07170-5 3 view
Seki DNA Res. Evaluation and application of RNA-Seq by MinION. 2018-11-20 10.1093/dnares/dsy038 1 view
Dura Nucleic Acids Res. scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3' mRNA profiling. 2018-11-20 10.1093/nar/gky1173 view
Czupalla Bio Protoc Collagenase-based Single Cell Isolation of Primary Murine Brain Endothelial Cells Using Flow Cytometry. 2018-11-20 10.21769/BioProtoc.3092 9 view
Lu Cell Rep The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification. 2018-11-20 10.1016/j.celrep.2018.10.084 8 view
Peng Immunity Seq-ing out the Killers of Mice and Men. 2018-11-20 10.1016/j.immuni.2018.11.007 view
Jia Nat Commun Single cell RNA-seq and ATAC-seq analysis of cardiac progenitor cell transition states and lineage settlement. 2018-11-19 10.1038/s41467-018-07307-6 16 view
Aulicino Nat Commun Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets. 2018-11-19 10.1038/s41467-018-07329-0 5 view
Lee Sci Rep Detection of correlated hidden factors from single cell transcriptomes using Iteratively Adjusted-SVA (IA-SVA). 2018-11-19 10.1038/s41598-018-35365-9 3 view
Nelson Nat Commun Publisher Correction: Single-cell RNA-seq reveals cell type-specific transcriptional signatures at the maternal-foetal interface during pregnancy. 2018-11-19 10.1038/ncomms16219 view
Heuvel Hum. Mol. Genet. Single-cell RNA-sequencing in facioscapulohumeral muscular dystrophy disease etiology and development. 2018-11-16 10.1093/hmg/ddy400 6 view
Chen Bioinformatics pyNVR: Investigating factors affecting feature selection from scRNA-seq data for lineage reconstruction. 2018-11-16 10.1093/bioinformatics/bty950 6 view
Hernández Sci Immunol Single-cell transcriptional analysis reveals ILC-like cells in zebrafish. 2018-11-16 10.1126/sciimmunol.aau5265 21 view
Lafzi Nat Protoc Tutorial: guidelines for the experimental design of single-cell RNA sequencing studies. 2018-11-16 10.1038/s41596-018-0073-y 22 view
Kimura Cancer Sci. Immunomodulatory activity of lenvatinib contributes to antitumor activity in the Hepa1-6 hepatocellular carcinoma model. 2018-11-16 10.1111/cas.13806 1 view
Zhang Mol. Cell Comparative Analysis of Droplet-Based Ultra-High-Throughput Single-Cell RNA-Seq Systems. 2018-11-16 10.1016/j.molcel.2018.10.020 73 view
Moerman Bioinformatics GRNBoost2 and Arboreto: efficient and scalable inference of gene regulatory networks. 2018-11-15 10.1093/bioinformatics/bty916 14 view
Hinohara Cancer Cell KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. 2018-11-14 10.1016/j.ccell.2018.10.014 17 view
Nilsson Allergy New insights into the origin of mast cells. 2018-11-14 10.1111/all.13668 2 view
Kuboki J. Pathol. Single-cell sequencing defines genetic heterogeneity in pancreatic cancer precursor lesions. 2018-11-14 10.1002/path.5194 17 view
Shifrut Cell Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function. 2018-11-13 10.1016/j.cell.2018.10.024 50 view
Alavi Nat Commun A web server for comparative analysis of single-cell RNA-seq data. 2018-11-13 10.1038/s41467-018-07165-2 13 view
Parekh Cell Syst Mapping Cellular Reprogramming via Pooled Overexpression Screens with Paired Fitness and Single-Cell RNA-Sequencing Readout. 2018-11-12 10.1016/j.cels.2018.10.008 view
Vuong PLoS Genet. Single-cell RNA-sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium. 2018-11-12 10.1371/journal.pgen.1007788 2 view
Chen Genome Biol. VIPER: variability-preserving imputation for accurate gene expression recovery in single-cell RNA sequencing studies. 2018-11-12 10.1186/s13059-018-1575-1 23 view
Behjati Ardakani Epigenetics Chromatin Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters. 2018-11-10 10.1186/s13072-018-0236-7 view
Balboa Elife Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes. 2018-11-09 10.7554/eLife.38519 21 view
Zhu Elife T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1. 2018-11-09 10.7554/eLife.38314 7 view
Khong Stem Cells Single-Cell Transcriptomics of Human Mesenchymal Stem Cells Reveal Age-Related Cellular Subpopulation Depletion and Impaired Regenerative Function. 2018-11-09 10.1002/stem.2934 13 view
Boroviak Development Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development. 2018-11-09 10.1242/dev.167833 38 view
Jindal Nat Commun Discovery of rare cells from voluminous single cell expression data. 2018-11-09 10.1038/s41467-018-07234-6 7 view
Lu J Mol Cell Biol Single-cell analyses identify distinct and intermediate states of zebrafish pancreatic islet development. 2018-11-08 10.1093/jmcb/mjy064 2 view
Jones Cell Stem Cell Quantitative Clonal Analysis and Single-Cell Transcriptomics Reveal Division Kinetics, Hierarchy, and Fate of Oral Epithelial Progenitor Cells. 2018-11-07 10.1016/j.stem.2018.10.015 15 view
Westoby Genome Biol. Simulation-based benchmarking of isoform quantification in single-cell RNA-seq. 2018-11-07 10.1186/s13059-018-1571-5 10 view
Yin J. Biol. Chem. Single-cell RNA-Seq analysis identifies a noncoding interleukin 4 (IL-4) RNA that post-transcriptionally up-regulates IL-4 production in T helper cells. 2018-11-07 10.1074/jbc.RA118.004111 view
Revinski Nat Commun CDC20B is required for deuterosome-mediated centriole production in multiciliated cells. 2018-11-07 10.1038/s41467-018-06768-z 17 view
Kumar Cell Rep Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics. 2018-11-06 10.1016/j.celrep.2018.10.047 47 view
Talwar Sci Rep AutoImpute: Autoencoder based imputation of single-cell RNA-seq data. 2018-11-05 10.1038/s41598-018-34688-x 37 view
Salzer Cell Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging. 2018-11-03 10.1016/j.cell.2018.10.012 51 view
Wang Sci Immunol Combination cancer immunotherapy targeting PD-1 and GITR can rescue CD8+ T cell dysfunction and maintain memory phenotype. 2018-11-02 10.1126/sciimmunol.aat7061 1 view
Bajpai Circ. Res. Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury. 2018-11-02 10.1161/CIRCRESAHA.118.314028 71 view
Wu Cell Stem Cell Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics. 2018-11-01 10.1016/j.stem.2018.10.010 91 view
Durruthy-Durruthy Front Genet Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the Chd7 Mutant Mouse Ear. 2018-11-01 10.3389/fgene.2018.00473 1 view
Jusino J Cancer Metastasis Treat Centrosome aberrations and chromosome instability contribute to tumorigenesis and intra-tumor heterogeneity. 2018-11-01 10.20517/2394-4722.2018.24 7 view
Tasic Nature Shared and distinct transcriptomic cell types across neocortical areas. 2018-11-01 10.1038/s41586-018-0654-5 169 view
Bhaduri Nature Single-cell sequencing paints diverse pictures of the brain. 2018-11-01 10.1038/d41586-018-07027-3 view
Shih PLoS ONE Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq. 2018-11-01 10.1371/journal.pone.0206785 8 view
Moffitt Science Molecular, spatial and functional single-cell profiling of the hypothalamic preoptic region. 2018-11-01 10.1126/science.aau5324 117 view
Bernard Clin. Cancer Res. Single Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression. 2018-11-01 10.1158/1078-0432.CCR-18-1955 34 view
Dobnikar Nat Commun Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels. 2018-11-01 10.1038/s41467-018-06891-x 1 view
Scott Cell Tissue Unit-ed: Lung Cells Team up to Drive Alveolar Macrophage Development. 2018-11-01 10.1016/j.cell.2018.10.031 1 view
Jerby-Arnon Cell A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade. 2018-11-01 10.1016/j.cell.2018.09.006 171 view
Wallrapp Immunol. Rev. Type 2 innate lymphoid cells in the induction and resolution of tissue inflammation. 2018-11-01 10.1111/imr.12702 6 view
Uniken Venema Gastroenterology Single-cell RNA Sequencing of Blood and Ileal T cells From Patients With Crohn's Disease Reveals Tissue-specific Characteristics and Drug Targets. 2018-11-01 10.1053/j.gastro.2018.10.046 view
Jiang Cell Discov Maintenance of human haematopoietic stem and progenitor cells in vitro using a chemical cocktail. 2018-11-01 10.1038/s41421-018-0059-5 4 view
Yang NPJ Breast Cancer An assessment of prognostic immunity markers in breast cancer. 2018-11-01 10.1038/s41523-018-0088-0 7 view
McTaggart BioTechniques Chromium sequencing: the doors open for genomics of obligate plant pathogens. 2018-11-01 10.2144/btn-2018-0019 4 view
Ye Kidney Dis (Basel) Understanding the Biology and Pathogenesis of the Kidney by Single-Cell Transcriptomic Analysis. 2018-11-01 10.1159/000492470 view
Lieberman PLoS ONE Correction: CaSTLe - Classification of single cells by transfer learning: Harnessing the power of publicly available single cell RNA sequencing experiments to annotate new experiments. 2018-11-01 10.1371/journal.pone.0208349 2 view
Valdes-Mora Front Immunol Single-Cell Transcriptomics in Cancer Immunobiology: The Future of Precision Oncology. 2018-11-01 10.3389/fimmu.2018.02582 24 view
See Front Immunol A Single-Cell Sequencing Guide for Immunologists. 2018-11-01 10.3389/fimmu.2018.02425 12 view
Wu PLoS ONE Characterization of sensory neuronal subtypes innervating mouse tongue. 2018-11-01 10.1371/journal.pone.0207069 2 view
Crinier Immunity High-Dimensional Single-Cell Analysis Identifies Organ-Specific Signatures and Conserved NK Cell Subsets in Humans and Mice. 2018-11-01 10.1016/j.immuni.2018.09.009 35 view
Ronen F1000Res netSmooth: Network-smoothing based imputation for single cell RNA-seq. 2018-11-01 10.12688/f1000research.13511.2 23 view
Bai PLoS ONE Evaluation of the capacities of mouse TCR profiling from short read RNA-seq data. 2018-11-01 10.1371/journal.pone.0207020 view
Bacon Front Immunol Single-Cell Analysis Identifies Thymic Maturation Delay in Growth-Restricted Neonatal Mice. 2018-11-01 10.3389/fimmu.2018.02523 view
Hosoya J. Immunol. High-Throughput Single-Cell Sequencing of both TCR-β Alleles. 2018-10-31 10.4049/jimmunol.1800774 view
Scimone Curr. Biol. foxF-1 Controls Specification of Non-body Wall Muscle and Phagocytic Cells in Planarians. 2018-10-31 10.1016/j.cub.2018.10.030 4 view
Ackers-Johnson Nat Commun Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease. 2018-10-30 10.1038/s41467-018-06894-8 8 view
Cembrowski Elife The subiculum is a patchwork of discrete subregions. 2018-10-30 10.7554/eLife.37701 view
Codeluppi Nat. Methods Spatial organization of the somatosensory cortex revealed by osmFISH. 2018-10-30 10.1038/s41592-018-0175-z 24 view
Dominguez Gutierrez Endocrinology Gene Signature of the Human Pancreatic ε-Cell. 2018-10-30 10.1210/en.2018-00833 view
Zhu Nat. Biotechnol. Identification of spatially associated subpopulations by combining scRNAseq and sequential fluorescence in situ hybridization data. 2018-10-29 10.1038/nbt.4260 1 view
Gerber Science Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. 2018-10-26 10.1126/science.aaq0681 30 view
Kim Circ. Res. Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models. 2018-10-26 10.1161/CIRCRESAHA.118.312804 59 view
Tanaka Cancer Med Single-cell RNA-seq analysis reveals the platinum resistance gene COX7B and the surrogate marker CD63. 2018-10-26 10.1002/cam4.1828 1 view
Biton Cell T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation. 2018-10-26 10.1016/j.cell.2018.10.008 67 view
Paul J Vis Exp Single-cell RNA Sequencing of Fluorescently Labeled Mouse Neurons Using Manual Sorting and Double In Vitro Transcription with Absolute Counts Sequencing (DIVA-Seq). 2018-10-26 10.3791/58690 1 view
Suber Respir. Res. FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells. 2018-10-25 10.1186/s12931-018-0910-0 1 view
Sommarin J Vis Exp A Combinatorial Single-cell Approach to Characterize the Molecular and Immunophenotypic Heterogeneity of Human Stem and Progenitor Populations. 2018-10-25 10.3791/57831 view
Fan J. Exp. Med. CD49b defines functionally mature Treg cells that survey skin and vascular tissues. 2018-10-24 10.1084/jem.20181442 10 view
Hagai Nature Gene expression variability across cells and species shapes innate immunity. 2018-10-24 10.1038/s41586-018-0657-2 39 view
Athar Nucleic Acids Res. ArrayExpress update - from bulk to single-cell expression data. 2018-10-24 10.1093/nar/gky964 53 view
Raj Nat Protoc Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT. 2018-10-23 10.1038/s41596-018-0058-x 15 view
Mok Cell Rep More Than the Sum of Its Parts: Single-Cell Transcriptomics Reveals Epidermal Cell States. 2018-10-23 10.1016/j.celrep.2018.10.041 1 view
Cheng Cell Rep Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution. 2018-10-23 10.1016/j.celrep.2018.09.006 42 view
Liu PLoS Biol. Quantitative assessment of cell population diversity in single-cell landscapes. 2018-10-22 10.1371/journal.pbio.2006687 1 view
MacParland Nat Commun Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations. 2018-10-22 10.1038/s41467-018-06318-7 127 view
Graham Nat. Med. Antigen discovery and specification of immunodominance hierarchies for MHCII-restricted epitopes. 2018-10-22 10.1038/s41591-018-0203-7 12 view
D'Gama Nat. Neurosci. Somatic mosaicism and neurodevelopmental disease. 2018-10-22 10.1038/s41593-018-0257-3 view
Yuan Nucleic Acids Res. CancerSEA: a cancer single-cell state atlas. 2018-10-17 10.1093/nar/gky939 18 view
Xiao Genome Biol. Holo-Seq: single-cell sequencing of holo-transcriptome. 2018-10-17 10.1186/s13059-018-1553-7 2 view
Müller Nature Genome organization and DNA accessibility control antigenic variation in trypanosomes. 2018-10-17 10.1038/s41586-018-0619-8 36 view
Cheung Endocrinology Single-cell RNA sequencing reveals novel markers of male pituitary stem cells and hormone-producing cell-types. 2018-10-17 10.1210/en.2018-00750 5 view
Joost Cell Rep Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing. 2018-10-16 10.1016/j.celrep.2018.09.059 2 view
Gubin Cell High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy. 2018-10-16 10.1016/j.cell.2018.09.030 62 view
Subramanian Parimalam Anal. Chem. Electrical Lysis and RNA Extraction from Single Cells Fixed by Dithiobis(succinimidyl propionate). 2018-10-16 10.1021/acs.analchem.8b02338 view
Liu Cancer Res. Circulating glioma cells exhibit stem cell-like properties. 2018-10-15 10.1158/0008-5472.CAN-18-0650 17 view
Marie Proc. Natl. Acad. Sci. U.S.A. Single-molecule DNA-mapping and whole-genome sequencing of individual cells. 2018-10-15 10.1073/pnas.1804194115 6 view
Owen Nat Commun Single cell RNA-seq reveals profound transcriptional similarity between Barrett's oesophagus and oesophageal submucosal glands. 2018-10-15 10.1038/s41467-018-06796-9 view
Matson J Vis Exp Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing. 2018-10-12 10.3791/58413 view
Guo Cell Res. The adult human testis transcriptional cell atlas. 2018-10-12 10.1038/s41422-018-0099-2 95 view
Molenaar Circ. Res. Single-Cell Sequencing of the Mammalian Heart. 2018-10-12 10.1161/CIRCRESAHA.118.313531 5 view
Ó hAinmhire Am. J. Physiol. Renal Physiol. A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition. 2018-10-10 10.1152/ajprenal.00460.2018 view
Gao Analyst Recent advances in single cell manipulation and biochemical analysis on microfluidics. 2018-10-09 10.1039/c8an01186a 25 view
Sharma Mol. Immunol. Using single cell analysis for translational studies in immune mediated diseases: Opportunities and challenges. 2018-10-06 10.1016/j.molimm.2018.09.020 3 view
Shi Brief. Bioinformatics Quantifying Waddington's epigenetic landscape: a comparison of single-cell potency measures. 2018-10-05 10.1093/bib/bby093 view
Zhang Nucleic Acids Res. CellMarker: a manually curated resource of cell markers in human and mouse. 2018-10-05 10.1093/nar/gky900 57 view
Manh Nguyen Appl. Environ. Microbiol. Effective soil extraction method for cultivating previously uncultured soil bacteria. 2018-10-05 10.1128/AEM.01145-18 view
Upadhaya J. Exp. Med. Kinetics of adult hematopoietic stem cell differentiation in vivo. 2018-10-05 10.1084/jem.20180136 16 view
Kilian J. Biol. Chem. Role of phospholipid synthesis in the development and differentiation of malaria parasites in the blood. 2018-10-04 10.1074/jbc.R118.003213 view
Svensson Mol. Cell RNA Velocity: Molecular Kinetics from Single-Cell RNA-Seq. 2018-10-04 10.1016/j.molcel.2018.09.026 8 view
Boulais Immunity The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors. 2018-10-04 10.1016/j.immuni.2018.08.019 7 view
Wurmus Gigascience PiGx: Reproducible genomics analysis pipelines with GNU Guix. 2018-10-02 10.1093/gigascience/giy123 11 view
Bradley Cell Rep Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. 2018-10-02 10.1016/j.celrep.2018.09.020 14 view
Qiu Nat. Med. Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease. 2018-10-01 10.1038/s41591-018-0194-4 7 view
Bresciani MethodsX An efficient dissociation protocol for generation of single cell suspension from zebrafish embryos and larvae. 2018-10-01 10.1016/j.mex.2018.10.009 8 view
Peng F1000Res Regulatory network characterization in development: challenges and opportunities. 2018-10-01 10.12688/f1000research.15271.1 view
Cho Lett Biomath Modelling acute myeloid leukaemia in a continuum of differentiation states. 2018-10-01 10.1080/23737867.2018.1472532 7 view
Schmidt Cardiovasc. Res. Single-cell transcriptomics in embryology: implications for cardiovascular science. 2018-10-01 10.1093/cvr/cvy193 view
Liang Comput Struct Biotechnol J A Review of Matched-pairs Feature Selection Methods for Gene Expression Data Analysis. 2018-10-01 10.1016/j.csbj.2018.02.005 13 view
Martinez Ramirez Ann. Oncol. Single-cell RNA sequencing of triple negative breast cancer patient-derived xenograft reveals distinct cellular populations spatially mapped to histological sections. 2018-10-01 10.1093/annonc/mdy304.002 view
Konstantinides Curr Opin Syst Biol Neuro-evo-devo in the single cell sequencing era. 2018-10-01 10.1016/j.coisb.2018.08.001 view
Guo Nat. Med. Publisher Correction: Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing. 2018-10-01 10.1038/s41591-018-0167-7 5 view
Mah F1000Res An accessible, interactive GenePattern Notebook for analysis and exploration of single-cell transcriptomic data. 2018-10-01 10.12688/f1000research.15830.1 view
Lieberman PLoS ONE CaSTLe - Classification of single cells by transfer learning: Harnessing the power of publicly available single cell RNA sequencing experiments to annotate new experiments. 2018-10-01 10.1371/journal.pone.0205499 19 view
Suryawanshi Sci Adv A single-cell survey of the human first-trimester placenta and decidua. 2018-10-01 10.1126/sciadv.aau4788 38 view
Apostolidis Front Immunol Single Cell RNA Sequencing Identifies HSPG2 and APLNR as Markers of Endothelial Cell Injury in Systemic Sclerosis Skin. 2018-10-01 10.3389/fimmu.2018.02191 4 view
Bryan Hum. Mol. Genet. Identifying core biological processes distinguishing human eye tissues with precise systems-level gene expression analyses and weighted correlation networks. 2018-10-01 10.1093/hmg/ddy239 6 view
Mays PLoS ONE Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression. 2018-10-01 10.1371/journal.pone.0205883 14 view
Tripathy Front Mol Neurosci Assessing Transcriptome Quality in Patch-Seq Datasets. 2018-10-01 10.3389/fnmol.2018.00363 view
Li J Vis Exp Single-cell Transcriptomic Analyses of Mouse Pancreatic Endocrine Cells. 2018-09-30 10.3791/58000 view
Chambers Respirology Transcriptomics and single-cell RNA-sequencing. 2018-09-28 10.1111/resp.13412 6 view
Hepler Elife Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. 2018-09-28 10.7554/eLife.39636 32 view
Nirmal Cancer Immunol Res Immune cell gene signatures for profiling the microenvironment of solid tumors. 2018-09-28 10.1158/2326-6066.CIR-18-0342 18 view
Meilhac Nat Rev Cardiol The deployment of cell lineages that form the mammalian heart. 2018-09-28 10.1038/s41569-018-0086-9 1 view
Biase iScience Rainbow-Seq: Combining Cell Lineage Tracing with Single-Cell RNA Sequencing in Preimplantation Embryos. 2018-09-28 10.1016/j.isci.2018.08.009 view
Daniszewski iScience Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media. 2018-09-28 10.1016/j.isci.2018.08.016 2 view
Cohen Cell Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting. 2018-09-28 10.1016/j.cell.2018.09.009 108 view
Ranu Nucleic Acids Res. Targeting individual cells by barcode in pooled sequence libraries. 2018-09-26 10.1093/nar/gky856 3