Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: Reside between the hepatocytes and small blood vessels in the liver. They are characterised by the presence of lipid droplets and thin protrusions extending around the blood vessels. Their activation in damaged liver leads to secretion of collagen and formation of scar tissue, leading to chronic fibrosis or cirrhosis.
Synonym(s): Perisinusoidal cells, Ito cells

Gene expression markers for Hepatic stellate cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
2
Mm Hs TIMP1 0.097 1 0 0.409 0 3 Hepatic stellate cells Endoderm Liver TIMP,CLGI TIMP metallopeptidase inhibitor 1 flag
2
Mm Hs IGFBP6 0.039 1 0 0.083 0.029 3 Hepatic stellate cells Endoderm Liver insulin like growth factor binding protein 6 flag
2
Mm Hs COL1A2 0.097 1 0.5 0.124 0.088 3 Hepatic stellate cells Endoderm Liver collagen type I alpha 2 chain Yflag
2
Mm Hs SPARC 0.307 1 0 0.23 0 5 Hepatic stellate cells Endoderm Liver ON secreted protein acidic and cysteine rich Yflag
2
Mm Hs TPM2 0.075 1 0 0.146 0 5 Hepatic stellate cells Endoderm Liver NEM4,AMCD1 tropomyosin 2 Yflag
1
Mm Hs COL3A1 0.086 1 0.5 0.099 0.081 4 Hepatic stellate cells Endoderm Liver EDS4A collagen type III alpha 1 chain Yflag
1
Mm Hs MYL9 0.081 1 0 0.16 0.063 7 Hepatic stellate cells Endoderm Liver MYRL2,MLC2,LC20,MRLC1 myosin light chain 9 flag
1
Mm Hs DCN 0.084 1 0.5 0.107 0.082 3 Hepatic stellate cells Endoderm Liver DSPG2,SLRR1B decorin Yflag
0
Mm Hs SYP 0.049 0 0 0.007 0 3 Hepatic stellate cells Endoderm Liver MRX96 synaptophysin Yflag
0
Mm Hs RELN 0.018 0 0 0.003 0 3 Hepatic stellate cells Endoderm Liver RL,PRO1598 reelin Yflag
0
Mm Hs VCL 0.018 0.5 0 0.067 0 1 Hepatic stellate cells Endoderm Liver vinculin Yflag
0
Mm Hs COL1A1 0.081 1 0.5 0.099 0.073 6 Hepatic stellate cells Endoderm Liver collagen type I alpha 1 chain Yflag
0
Mm Hs TAGLN 0.01 0 0 0.001 0 4 Hepatic stellate cells Endoderm Liver SM22,WS3-10,TAGLN1,DKFZp686P11128 transgelin flag
0
Mm Hs RBP1 0.114 0.5 0 0.164 0 1 Hepatic stellate cells Endoderm Liver CRBP1,CRBP,RBPC,CRBPI retinol binding protein 1 flag
0
Mm Hs MEG3 0.288 0.5 0 0.115 0.335 3 Hepatic stellate cells Endoderm Liver GTL2,NCRNA00023,LINC00023,onco-lncRNA-83 maternally expressed 3 flag
0
Mm Hs BGN 0.097 1 0.5 0.065 0.107 2 Hepatic stellate cells Endoderm Liver DSPG1,SLRR1A biglycan flag
0
Mm Hs IGFBP7 0.172 1 0.5 0.239 0.163 3 Hepatic stellate cells Endoderm Liver MAC25,IGFBP-7,FSTL2 insulin like growth factor binding protein 7 Yflag
0
Mm Hs IGFBP3 0.031 0.5 0.5 0.059 0.026 4 Hepatic stellate cells Endoderm Liver IBP3,BP-53 insulin like growth factor binding protein 3 flag
0
Mm Hs CYR61 0.125 1 0.5 0.135 0.124 1 Hepatic stellate cells Endoderm Liver IGFBP10 cysteine rich angiogenic inducer 61 flag
0
Mm Hs OLFML3 0.053 0.5 0 0.031 0.058 3 Hepatic stellate cells Endoderm Liver HNOEL-iso,OLF44 olfactomedin like 3 flag
0
Mm Hs CCL2 0.037 1 0.5 0.064 0.032 6 Hepatic stellate cells Endoderm Liver MCP1,MCP-1,MCAF,SMC-CF,GDCF-2,HC11,MGC9434,SCYA2 C-C motif chemokine ligand 2 Yflag
0
Mm Hs COLEC11 0.002 0.5 0 0.007 0.001 2 Hepatic stellate cells Endoderm Liver MGC3279,CL-K1 collectin subfamily member 11 Yflag
0
Mm Hs HGF 0.002 0 0 0.008 0.001 3 Hepatic stellate cells Endoderm Liver F-TCF,HGFB,HPTA,DFNB39 hepatocyte growth factor Yflag
0
Mm Hs PNPLA3 0 0 0 0 0 1 Hepatic stellate cells Endoderm Liver dJ796I17.1,FLJ22012,adiponutrin,iPLA2epsilon,C22orf20,ADPN patatin like phospholipase domain containing 3 flag
0
Mm Hs CYGB 0.038 0 0.5 0.022 0.043 3 Hepatic stellate cells Endoderm Liver HGB,STAP cytoglobin Yflag
0
Mm Hs PPARG 0.006 0.5 0 0.011 0.005 8 Hepatic stellate cells Endoderm Liver PPARG1,PPARG2,NR1C3,PPARgamma peroxisome proliferator activated receptor gamma Yflag
0
Mm Hs PDGFRA 0.044 0 0.5 0.048 0.044 6 Hepatic stellate cells Endoderm Liver CD140a,PDGFR2,GAS9 platelet derived growth factor receptor alpha Yflag
0
Mm Hs RGS5 0.043 NA NA NA NA 6 Hepatic stellate cells Endoderm Liver regulator of G protein signaling 5 Yflag
0
Mm Hs PPARA 0.001 0 0 0.003 0.001 3 Hepatic stellate cells Endoderm Liver hPPAR,NR1C1,PPAR peroxisome proliferator activated receptor alpha flag
0
Mm Hs FOXF1 0.008 0 0 0.008 0.008 4 Hepatic stellate cells Endoderm Liver FREAC1,FKHL5 forkhead box F1 Yflag
0
Mm Hs NR1H4 0.002 0 0 0.001 0.002 2 Hepatic stellate cells Endoderm Liver FXR,RIP14,HRR1,HRR-1 nuclear receptor subfamily 1 group H member 4 flag
0
Mm Hs CTGF 0.028 1 0.5 0.099 0.012 11 Hepatic stellate cells Endoderm Liver IGFBP8,CCN2 connective tissue growth factor flag
0
Mm Hs SEMA7A 0.006 0 0 0 0 2 Hepatic stellate cells Endoderm Liver H-Sema-L,CD108,SEMAL semaphorin 7A (John Milton Hagen blood group) Yflag
0
Hs AGTR1 0 0 0 0.002 0 1 Hepatic stellate cells Endoderm Liver AT2R1,AGTR1A,AT2R1A,HAT1R,AG2S,AT2R1B,AT1B,AGTR1B angiotensin II receptor type 1 Yflag
0
Mm Hs ADAMTS13 0 0 0 0 0 2 Hepatic stellate cells Endoderm Liver VWFCP,vWF-CP,FLJ42993,MGC118899,MGC118900,DKFZp434C2322,C9orf8 ADAM metallopeptidase with thrombospondin type 1 motif 13 Yflag
0
Mm Hs WT1 0.01 0 0 0.023 0 10 Hepatic stellate cells Endoderm Liver WIT-2,AWT1,NPHS4,GUD Wilms tumor 1 Yflag
0
Mm Hs FGF10 0.001 0 0 0.001 0.002 3 Hepatic stellate cells Endoderm Liver fibroblast growth factor 10 Yflag
0
Mm Hs GFAP 0.013 0 0.5 0.006 0.015 11 Hepatic stellate cells Endoderm Liver FLJ45472 glial fibrillary acidic protein Yflag
0
Mm Hs NGFR 0.007 0 0 0.002 0.007 6 Hepatic stellate cells Endoderm Liver TNFRSF16,CD271,p75NTR nerve growth factor receptor flag
0
Mm Hs VEGFA 0.021 0 0 0.025 0 10 Hepatic stellate cells Endoderm Liver VEGF-A,VPF,VEGF vascular endothelial growth factor A Yflag
0
Mm Hs ACTA2 0.035 0.5 0 0.019 0.039 9 Hepatic stellate cells Endoderm Liver ACTSA actin, alpha 2, smooth muscle, aorta Yflag
0
Mm Hs MYB 0.027 0 0 0.013 0.028 3 Hepatic stellate cells Endoderm Liver c-myb MYB proto-oncogene, transcription factor flag
0
Mm Hs FAP 0.006 0 0 0.003 0.007 4 Hepatic stellate cells Endoderm Liver fibroblast activation protein alpha flag
0
Mm Hs SLC8A1 0.002 0 0 0.006 0 2 Hepatic stellate cells Endoderm Liver NCX1 solute carrier family 8 member A1 flag
-1
Mm Hs ALB 0.008 0.5 0 0.028 0.004 4 Hepatic stellate cells Endoderm Liver albumin Yflag
-1
Mm Hs DES 0.021 0 0.5 0.009 0.023 11 Hepatic stellate cells Endoderm Liver CMD1I,CSM1,CSM2 desmin Yflag

Datasets with computationally identified Hepatic stellate cells

SRA SRS tissue cluster cell type p-value FDR View
SRA203368 SRS866906 Retina 18 Hepatic stellate cells 7.03E-5 6.43E-3 view data
SRA640325 SRS2769051 Lung proximal airway stromal cells 22 Hepatic stellate cells 2.90E-4 1.60E-2 view data
SRA628029 SRS3348009 Mesenteric lymph nodes 0 Hepatic stellate cells 4.12E-4 4.02E-2 view data
SRA716608 SRS3391630 Liver 12 Hepatic stellate cells 5.87E-5 5.19E-3 view data