Cell type gene expression markers


This is a list of gene expression markers are used to define cell types. Green rows indicate canonical markers (classical markers used to define the cell type).

Summary: 8286 associations (178 cell types, 4679 gene symbols, 29 tissues); Last updated: 27/03/2020 10:44:00 CET

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Description: A type of multipolar neuron found in areas of the brain including the cerebral cortex, the hippocampus, and the amygdala. Pyramidal neurons are the primary excitation units of the mammalian prefrontal cortex and the corticospinal tract.
Synonym(s): Pyramidal neurons

Gene expression markers for Pyramidal cells

Vote(s) Species Official gene symbol UI Sensitivity (human) Sensitivity (mouse) Specificity (human) Specificity (mouse) Marker count Cell type Germ layer Organ Aliases Product description Disease Action
4
Mm Hs NRGN 0.031 0 1 0.011 0.034 6 Pyramidal cells Ectoderm Brain neurogranin flag
0
Mm Hs DAB1 0.045 0 1 0.002 0.057 3 Pyramidal cells Ectoderm Brain DAB1, reelin adaptor protein flag
0
Mm Hs DLG4 0.022 0 0 0 0.028 3 Pyramidal cells Ectoderm Brain PSD-95,PSD95,SAP90,SAP-90 discs large MAGUK scaffold protein 4 flag
0
Mm Hs CCM2 0.052 0 0 0.044 0.051 2 Pyramidal cells Ectoderm Brain MGC4607,OSM,C7orf22 CCM2 scaffold protein Yflag
0
Mm Hs MAP2 0.179 0 1 0.027 0.216 1 Pyramidal cells Ectoderm Brain MAP2A,MAP2B,MAP2C microtubule associated protein 2 flag
0
Mm Hs CALB1 0.019 0 0 0.001 0.024 6 Pyramidal cells Ectoderm Brain CALB calbindin 1 flag
0
Mm Hs ADRB2 0.016 0 0 0.01 0.018 3 Pyramidal cells Ectoderm Brain ADRBR,B2AR,ADRB2R adrenoceptor beta 2 Yflag
0
Mm Hs RTN4 0.553 0 0 0.505 0 1 Pyramidal cells Ectoderm Brain NSP-CL,KIAA0886,NOGO,ASY reticulon 4 flag
0
Mm Hs PDE2A 0 0 0 0.001 0 1 Pyramidal cells Ectoderm Brain phosphodiesterase 2A flag
0
Mm Hs KCNB1 0.015 0 0 0 0.019 1 Pyramidal cells Ectoderm Brain Kv2.1 potassium voltage-gated channel subfamily B member 1 Yflag
0
Mm Hs KCNB2 0.007 0 0 0 0.008 1 Pyramidal cells Ectoderm Brain Kv2.2 potassium voltage-gated channel subfamily B member 2 flag
0
Mm Hs KCNQ2 0.014 0 0 0.023 0.013 1 Pyramidal cells Ectoderm Brain Kv7.2,ENB1,KCNA11,HNSPC potassium voltage-gated channel subfamily Q member 2 Yflag
0
Mm Hs KCNQ3 0.017 0 0 0.001 0.021 1 Pyramidal cells Ectoderm Brain Kv7.3,EBN2 potassium voltage-gated channel subfamily Q member 3 Yflag
0
Mm Hs SATB2 0.015 0 0 0.004 0 1 Pyramidal cells Ectoderm Brain KIAA1034,FLJ21474 SATB homeobox 2 Yflag
0
Mm Hs OXTR 0.001 0 0 0.001 0.002 1 Pyramidal cells Ectoderm Brain oxytocin receptor flag
0
Mm Hs CCK 0.033 0 0 0.003 0.039 7 Pyramidal cells Ectoderm Brain cholecystokinin flag
0
Mm Hs KCND2 0.009 0 0 0.001 0.011 1 Pyramidal cells Ectoderm Brain Kv4.2,RK5,KIAA1044 potassium voltage-gated channel subfamily D member 2 flag
0
Mm Hs KCND3 0.004 0 0 0.002 0.005 1 Pyramidal cells Ectoderm Brain Kv4.3,KSHIVB,SCA22,SCA19 potassium voltage-gated channel subfamily D member 3 Yflag
0
Mm Hs GRIA3 0.02 0 0 0.002 0.023 3 Pyramidal cells Ectoderm Brain GluA3,GLURC,MRX94,GLUR3 glutamate ionotropic receptor AMPA type subunit 3 Yflag
0
Mm Hs CD3E 0.041 0 0 0.1 0.03 4 Pyramidal cells Ectoderm Brain CD3e molecule Yflag
0
Mm Hs CAMK2A 0.026 0 1 0 0.032 3 Pyramidal cells Ectoderm Brain KIAA0968,CAMKA calcium/calmodulin dependent protein kinase II alpha flag
0
Mm Hs GRM1 0.004 0 0 0 0.005 2 Pyramidal cells Ectoderm Brain GPRC1A,mGlu1,MGLUR1,PPP1R85 glutamate metabotropic receptor 1 Yflag
0
Mm Hs GRM5 0.033 0 1 0 0.042 4 Pyramidal cells Ectoderm Brain MGLUR5,GPRC1E,mGlu5,PPP1R86 glutamate metabotropic receptor 5 flag
0
Mm Hs TBR1 0.018 0 0 0.001 0 3 Pyramidal cells Ectoderm Brain T-box, brain 1 flag
0
Mm Hs POU3F1 0.013 0 0 0 0.017 4 Pyramidal cells Ectoderm Brain OCT6,SCIP,OTF6 POU class 3 homeobox 1 flag
0
Mm Hs EMX1 0.023 0 0 0 0.029 2 Pyramidal cells Ectoderm Brain empty spiracles homeobox 1 flag
0
Mm Hs FEZF2 0.008 0 0 0.001 0.01 2 Pyramidal cells Ectoderm Brain FLJ10142,FKSG36,TOF,FEZL,Zfp312,ZNF312 FEZ family zinc finger 2 flag
0
Mm Hs KCNN4 0.027 0 0 0.01 0.029 3 Pyramidal cells Ectoderm Brain KCa3.1,hSK4,hKCa4,hIKCa1,IK potassium calcium-activated channel subfamily N member 4 Yflag
0
Mm Hs SPINK8 0.002 0 0 0.001 0 1 Pyramidal cells Ectoderm Brain serine peptidase inhibitor, Kazal type 8 (putative) flag
0
Mm Hs PCP4 0.083 0 1 0.019 0.097 3 Pyramidal cells Ectoderm Brain PEP-19 Purkinje cell protein 4 flag
0
Mm Hs SYNPR 0.022 0 0 0.001 0 5 Pyramidal cells Ectoderm Brain MGC26651 synaptoporin flag
0
Mm Hs NR4A2 0.033 0 0 0.078 0.026 4 Pyramidal cells Ectoderm Brain TINUR,NOT,RNR1,HZF-3,NURR1 nuclear receptor subfamily 4 group A member 2 Yflag
0
Mm Hs AGER 0.011 0 0 0.001 0.014 6 Pyramidal cells Ectoderm Brain SCARJ1 advanced glycosylation end-product specific receptor flag
0
Mm Hs GRIN2D 0.002 0 0 0 0.002 2 Pyramidal cells Ectoderm Brain GluN2D,EB11,NR2D,NMDAR2D glutamate ionotropic receptor NMDA type subunit 2D flag
-1
Mm Hs YWHAZ 0.497 0 0 0.519 0 1 Pyramidal cells Ectoderm Brain KCIP-1,14-3-3-zeta,YWHAD tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta flag

Datasets with computationally identified Pyramidal cells

SRA SRS tissue cluster cell type p-value FDR View
SRA675945 SRS3100154 Hippocampus 8 Pyramidal cells 7.15E-5 6.65E-3 view data